PT1885753E - Produção de proteína recombinante de ligação a il-18 - Google Patents

Produção de proteína recombinante de ligação a il-18 Download PDF

Info

Publication number
PT1885753E
PT1885753E PT06763472T PT06763472T PT1885753E PT 1885753 E PT1885753 E PT 1885753E PT 06763472 T PT06763472 T PT 06763472T PT 06763472 T PT06763472 T PT 06763472T PT 1885753 E PT1885753 E PT 1885753E
Authority
PT
Portugal
Prior art keywords
production
binding protein
recombinant
composition
relates
Prior art date
Application number
PT06763472T
Other languages
English (en)
Inventor
Thierry Ziegler
Urs Weber
Original Assignee
Ares Trading Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ares Trading Sa filed Critical Ares Trading Sa
Publication of PT1885753E publication Critical patent/PT1885753E/pt

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/16Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • A61P17/06Antipsoriatics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00Drugs for skeletal disorders
    • A61P19/02Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • A61P37/06Immunosuppressants, e.g. drugs for graft rejection
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/08Antiallergic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/10Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Immunology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Zoology (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Toxicology (AREA)
  • Rheumatology (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Vascular Medicine (AREA)
  • Diabetes (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Dermatology (AREA)
  • Communicable Diseases (AREA)
  • Pain & Pain Management (AREA)
  • Oncology (AREA)
  • Urology & Nephrology (AREA)
  • Hematology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Transplantation (AREA)
  • Pulmonology (AREA)
  • Epidemiology (AREA)
PT06763472T 2005-06-03 2006-06-01 Produção de proteína recombinante de ligação a il-18 PT1885753E (pt)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US68763105P 2005-06-03 2005-06-03
EP05104878 2005-06-03
EP05106429 2005-07-13

Publications (1)

Publication Number Publication Date
PT1885753E true PT1885753E (pt) 2011-10-06

Family

ID=44352415

Family Applications (2)

Application Number Title Priority Date Filing Date
PT06763472T PT1885753E (pt) 2005-06-03 2006-06-01 Produção de proteína recombinante de ligação a il-18
PT10184728T PT2267024E (pt) 2005-06-03 2006-06-01 Produção de proteína de ligação a il-18 recombinante

Family Applications After (1)

Application Number Title Priority Date Filing Date
PT10184728T PT2267024E (pt) 2005-06-03 2006-06-01 Produção de proteína de ligação a il-18 recombinante

Country Status (15)

Country Link
US (2) US7691611B2 (pt)
EP (2) EP2267024B1 (pt)
JP (2) JP5199073B2 (pt)
AT (2) ATE517917T1 (pt)
AU (1) AU2006254103B2 (pt)
CA (1) CA2609060C (pt)
CY (2) CY1111969T1 (pt)
DK (2) DK2267024T3 (pt)
ES (2) ES2370417T3 (pt)
IL (1) IL187838A (pt)
NO (1) NO342802B1 (pt)
PL (2) PL1885753T3 (pt)
PT (2) PT1885753E (pt)
SI (2) SI2267024T1 (pt)
WO (1) WO2006128908A1 (pt)

Families Citing this family (25)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR101111103B1 (ko) * 2000-02-10 2012-02-13 아보트 러보러터리즈 사람 인터류킨-18에 결합하는 항체 및 이를 제조하고 사용하는 방법
SI1601776T1 (sl) 2003-03-11 2008-10-31 Serono Lab Ekspresijski vektorji, ki vsebujejo mcmv ie2 promotor
CA2524403C (en) * 2003-05-13 2013-07-09 Applied Research Systems Ars Holding N.V. Active variants of the il-18 binding protein and medical uses thereof
WO2005040384A1 (en) 2003-10-21 2005-05-06 Applied Research Systems Ars Holding N.V. Minimal dna sequence acting as a chromatin insulator and its use in protein expression
PT1689777E (pt) 2003-11-05 2007-05-31 Ares Trading Sa Processo para a purificação da proteína de ligação a il-18
US7968684B2 (en) * 2003-11-12 2011-06-28 Abbott Laboratories IL-18 binding proteins
ES2292127T3 (es) 2004-03-01 2008-03-01 Ares Trading S.A. Uso de un medio de cultivo celular exento de suero para la produccion de il-18bp en celulas de mamiferos.
WO2006003134A1 (en) 2004-06-29 2006-01-12 Ares Trading S.A. Process for the purification of il-18 binding protein
PT1891088E (pt) 2005-06-10 2011-12-19 Ares Trading Sa Processo para a purificação da proteína de ligação il-18
US20160145589A1 (en) 2011-06-24 2016-05-26 Green Cross Corporation Composition and formulation comprising recombinant human iduronate-2-sulfatase and preparation method thereof
KR101857380B1 (ko) * 2011-07-01 2018-05-11 암젠 인크 포유동물 세포 배양
US20140004097A1 (en) * 2012-06-29 2014-01-02 Shire Human Genetic Therapies, Inc. Method of producing recombinant iduronate-2-sulfatase
KR101380740B1 (ko) 2012-06-29 2014-04-11 쉐어 휴먼 제네텍 세러피스, 인코포레이티드 이듀로네이트-2-설파타제의 정제
US9150841B2 (en) 2012-06-29 2015-10-06 Shire Human Genetic Therapies, Inc. Cells for producing recombinant iduronate-2-sulfatase
US9677105B2 (en) 2013-03-14 2017-06-13 Momenta Pharmaceuticals, Inc. Methods of cell culture
US9217168B2 (en) 2013-03-14 2015-12-22 Momenta Pharmaceuticals, Inc. Methods of cell culture
US8956830B2 (en) 2013-03-14 2015-02-17 Momenta Pharmaceuticals, Inc. Methods of cell culture
EP3391942A1 (en) 2013-03-26 2018-10-24 Coherus Biosciences, Inc. Protein production method
SG11201601717VA (en) * 2013-09-05 2016-04-28 Ab2 Bio Sa Il-18 binding protein (il-18bp) in inflammatory diseases
USD759075S1 (en) * 2014-04-11 2016-06-14 Nutonian, Inc. Display screen with graphical user interface
USD759076S1 (en) * 2014-04-18 2016-06-14 Nutonian, Inc. Display screen with graphical user interface
WO2016139297A1 (en) 2015-03-05 2016-09-09 Ab2 Bio Sa Il-18 binding protein (il-18bp) and antibodies in inflammatory diseases
KR101789509B1 (ko) * 2015-11-05 2017-10-26 주식회사 프로젠 재조합 인간 갑상선 자극 호르몬을 포함하는 조성물 및 상기 재조합 인간 갑상선 자극 호르몬의 생산 방법
CN118580925A (zh) 2017-10-16 2024-09-03 里珍纳龙药品有限公司 灌注生物反应器及相关使用方法
CA3099163A1 (en) 2018-05-01 2019-11-07 Amgen Inc. Antibodies with modulated glycan profiles

Family Cites Families (37)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4588585A (en) 1982-10-19 1986-05-13 Cetus Corporation Human recombinant cysteine depleted interferon-β muteins
US4737462A (en) 1982-10-19 1988-04-12 Cetus Corporation Structural genes, plasmids and transformed cells for producing cysteine depleted muteins of interferon-β
US4959314A (en) 1984-11-09 1990-09-25 Cetus Corporation Cysteine-depleted muteins of biologically active proteins
US5116943A (en) 1985-01-18 1992-05-26 Cetus Corporation Oxidation-resistant muteins of Il-2 and other protein
US5266476A (en) 1985-06-18 1993-11-30 Yeda Research & Development Co., Ltd. Fibrous matrix for in vitro cell cultivation
US5017691A (en) 1986-07-03 1991-05-21 Schering Corporation Mammalian interleukin-4
US4879111A (en) 1986-04-17 1989-11-07 Cetus Corporation Treatment of infections with lymphokines
US4965195A (en) 1987-10-26 1990-10-23 Immunex Corp. Interleukin-7
US4904584A (en) 1987-12-23 1990-02-27 Genetics Institute, Inc. Site-specific homogeneous modification of polypeptides
RU2166955C2 (ru) 1991-01-18 2001-05-20 Эмген Инк. Способ лечения и профилактики заболеваний, обусловленных повышением уровня фактора, вызывающего некроз опухолевых клеток
JP4306813B2 (ja) * 1995-09-19 2009-08-05 アスビオファーマ株式会社 動物細胞の新規培養方法
HUP9900619A3 (en) 1996-02-20 2001-11-28 Applied Research Systems Hybrid proteins which form heterodimers
IL127891A0 (en) 1996-07-12 1999-10-28 Genentech Inc Chimeric heteromultimeter adhesins
IL121860A0 (en) * 1997-08-14 1998-02-22 Yeda Res & Dev Interleukin-18 binding proteins their preparation and use
EP1194539A2 (en) 1999-06-25 2002-04-10 Universität Zürich Hetero-associating coiled-coil peptides and screening method therefor
AU782496B2 (en) 1999-07-13 2005-08-04 Bolder Biotechnology, Inc. Immunoglobulin fusion proteins
IL131047A0 (en) 1999-07-22 2001-01-28 Yeda Res & Dev Use of il-18 inhibitors
UA74557C2 (en) * 1999-09-03 2006-01-16 Applied Research Systems A method for producing a heterologous secreted protein from chinese hamster ovaries cells grown on microcarriers
KR20070057282A (ko) 2000-02-21 2007-06-04 어플라이드 리서치 시스템스 에이알에스 홀딩 엔.브이. Il-18 저해물질의 용도
EA005410B1 (ru) 2000-05-05 2005-02-24 Апплайд Резеч Системз Арс Холдинг Н.В. Применение ингибиторов il-18 для лечения и/или предотвращения атеросклероза
IL140110A0 (en) * 2000-12-05 2002-02-10 Applied Research Systems Improvement of homogeneity and secretion of recombinant proteins in mammalian systems
SK287620B6 (sk) 2001-01-29 2011-04-05 Laboratoires Serono Sa Použitie IL-18 inhibítorov
KR100862136B1 (ko) 2001-03-08 2008-10-09 아레스 트레이딩 에스.아. 인터루킨-18 변이체, 이들의 생산 및 용도
WO2002092008A2 (en) 2001-05-16 2002-11-21 Yeda Research And Development Co., Ltd. Use of il-18 inhibitors for the treatement or prevention of sepsis
EE05263B1 (et) 2001-05-25 2010-02-15 Ares Trading S.A. IL-18 inhibiitorite kasutamine keskn„rvissteemi kahjustuste raviks v?i ennetamiseks
UA78516C2 (en) 2001-08-10 2007-04-10 Applied Research Systems Use of inhibitors of il-18 for treatment and/or prevention of hypersensitivity disorders, and in particular of delayed-type hypersensitivity
KR20050004809A (ko) 2002-03-22 2005-01-12 어플라이드 리서치 시스템스 에이알에스 홀딩 엔.브이. 말초 맥관 질환 치료 및/또는 예방에 사용되는 il-18저해제
WO2004020639A2 (en) 2002-08-14 2004-03-11 Avidis Sa Production of multimeric fusion proteins using a c4bp scaffold
CA2501459A1 (en) 2002-10-11 2004-04-22 Zymogenetics, Inc. Production of homotrimeric fusion proteins
PL377731A1 (pl) * 2002-12-23 2006-02-06 Bristol-Myers Squibb Company Sposoby hodowli komórek ssaczych do wytwarzania białka
SI1601776T1 (sl) 2003-03-11 2008-10-31 Serono Lab Ekspresijski vektorji, ki vsebujejo mcmv ie2 promotor
CA2524403C (en) 2003-05-13 2013-07-09 Applied Research Systems Ars Holding N.V. Active variants of the il-18 binding protein and medical uses thereof
WO2005040384A1 (en) 2003-10-21 2005-05-06 Applied Research Systems Ars Holding N.V. Minimal dna sequence acting as a chromatin insulator and its use in protein expression
PT1689777E (pt) * 2003-11-05 2007-05-31 Ares Trading Sa Processo para a purificação da proteína de ligação a il-18
ES2292127T3 (es) 2004-03-01 2008-03-01 Ares Trading S.A. Uso de un medio de cultivo celular exento de suero para la produccion de il-18bp en celulas de mamiferos.
WO2006003134A1 (en) 2004-06-29 2006-01-12 Ares Trading S.A. Process for the purification of il-18 binding protein
PT1891088E (pt) 2005-06-10 2011-12-19 Ares Trading Sa Processo para a purificação da proteína de ligação il-18

Also Published As

Publication number Publication date
JP5199073B2 (ja) 2013-05-15
JP2013048633A (ja) 2013-03-14
AU2006254103A1 (en) 2006-12-07
JP5837476B2 (ja) 2015-12-24
US20080199913A1 (en) 2008-08-21
EP1885753B1 (en) 2011-07-27
EP2267024B1 (en) 2012-05-09
CY1113056T1 (el) 2016-04-13
CA2609060C (en) 2014-07-15
US20100137195A1 (en) 2010-06-03
NO342802B1 (no) 2018-08-06
EP1885753A1 (en) 2008-02-13
ES2385639T3 (es) 2012-07-27
CY1111969T1 (el) 2015-11-04
US7691611B2 (en) 2010-04-06
ES2370417T3 (es) 2011-12-15
SI1885753T1 (sl) 2011-12-30
ATE557038T1 (de) 2012-05-15
SI2267024T1 (sl) 2012-09-28
DK2267024T3 (da) 2012-06-25
CA2609060A1 (en) 2006-12-07
NO20076672L (no) 2008-02-22
IL187838A (en) 2011-07-31
PL2267024T3 (pl) 2012-10-31
PT2267024E (pt) 2012-06-01
DK1885753T3 (da) 2011-10-03
ATE517917T1 (de) 2011-08-15
PL1885753T3 (pl) 2011-12-30
AU2006254103B2 (en) 2012-09-06
EP2267024A1 (en) 2010-12-29
IL187838A0 (en) 2008-03-20
WO2006128908A1 (en) 2006-12-07
JP2008541748A (ja) 2008-11-27

Similar Documents

Publication Publication Date Title
SI2267024T1 (sl) Proizvodnja rekombinantnega IL-18 vezavnega proteina
HK1120052A1 (en) Process for the preparation of glycosylated interferon beta
IL183610A0 (en) Process for producing polypeptide mixtures using hydrogenolysis
HK1114878A1 (en) Methods for producing polypeptides by regulating polypeptide association
EP1873128A4 (en) FIRE-RESISTANT MATERIAL, MANUFACTURING METHOD AND RAW MATERIAL FOR FIRE-RESISTANT MATERIAL
EP1970399A4 (en) METHOD FOR PRODUCING A POLYGLYCOLIC ACID RESIN COMPOSITION
EP1811027A4 (en) POLYNUCLEOTIDE FOR THE PRODUCTION OF RECOMBINANT PROTEIN THROUGH SILICONS
IL187935A0 (en) Process for the purification of il-18 binding protein
EP1950191A4 (en) PROCESS FOR PRODUCING 3,3,3-TRIFLUOROPROPIONIC ACID
EP1748071A4 (en) PROCESS FOR PRODUCTION OF POLYPEPTIDE
EP1862079A4 (en) PROCESS FOR PRODUCING SOY PROTEIN
ZA200711011B (en) A recombinant method for production of an erythropoiesis stimulating protein
ZA200803138B (en) Bioleaching process control
ZA200801497B (en) Methionine producing recombinant microorganisms
EP2261243A3 (en) Hemopexin-like structure as polypeptide-scaffold
EP1930310A4 (en) PROCESS FOR PRODUCING 3,3,3-TRIFLUOROPROPIONALDEHYDE
GB0501253D0 (en) Process for the production of olefins
EP1852518A4 (en) METHOD FOR PRODUCING MULTIFUNCTIONAL MATERIAL
EP1935981A4 (en) PROCESS FOR PRODUCING RECOMBINANT PROTEIN
ZA200711006B (en) A process comprising codon optimization for the production of recombinant activated human protein c for the treatment of sepsis
EP1860207A4 (en) TARGET PROCESS
MD2572F1 (en) Process for obtaining tomato recombinant forms
ZA200805149B (en) Recombinant production of heparin binding proteins
WO2008098693A3 (en) Convergent synthesis of glp-1
AU2005904288A0 (en) Improved process for silica manufacture