DK0627406T3 - 2-Amino-1,3-propandiolforbindelser og immunundertrykkende midler - Google Patents

2-Amino-1,3-propandiolforbindelser og immunundertrykkende midler

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Publication number
DK0627406T3
DK0627406T3 DK93923035T DK93923035T DK0627406T3 DK 0627406 T3 DK0627406 T3 DK 0627406T3 DK 93923035 T DK93923035 T DK 93923035T DK 93923035 T DK93923035 T DK 93923035T DK 0627406 T3 DK0627406 T3 DK 0627406T3
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Denmark
Prior art keywords
optionally substituted
amino
same
immunosuppressants
propanediol
Prior art date
Application number
DK93923035T
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Danish (da)
English (en)
Inventor
Tadashi Mishina
Kunitomo Adachi
Kenji Chiba
Tetsuro Fujita
Shigeo Sasaki
Masahiko Yoneta
Original Assignee
Taito Co
Yoshitomi Pharmaceutical
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First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=26499282&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DK0627406(T3) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Taito Co, Yoshitomi Pharmaceutical filed Critical Taito Co
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Publication of DK0627406T3 publication Critical patent/DK0627406T3/da

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    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/30—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
    • C07D207/32—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • C07D207/325—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms with substituted hydrocarbon radicals directly attached to the ring nitrogen atom
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    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
    • A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
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    • A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
    • A61K31/235—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids having an aromatic ring attached to a carboxyl group
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    • C07C215/34—Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being unsaturated and containing six-membered aromatic rings containing hydroxy groups and carbon atoms of six-membered aromatic rings bound to the same carbon atom of the carbon skeleton and at least one hydroxy group bound to another carbon atom of the carbon skeleton
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    • C07C215/48—Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups bound to carbon atoms of at least one six-membered aromatic ring and amino groups bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton with amino groups linked to the six-membered aromatic ring, or to the condensed ring system containing that ring, by carbon chains not further substituted by hydroxy groups
    • C07C215/54—Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups bound to carbon atoms of at least one six-membered aromatic ring and amino groups bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton with amino groups linked to the six-membered aromatic ring, or to the condensed ring system containing that ring, by carbon chains not further substituted by hydroxy groups linked by carbon chains having at least three carbon atoms between the amino groups and the six-membered aromatic ring or the condensed ring system containing that ring
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    • C07C215/56—Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups bound to carbon atoms of at least one six-membered aromatic ring and amino groups bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton with amino groups linked to the six-membered aromatic ring, or to the condensed ring system containing that ring, by carbon chains further substituted by hydroxy groups
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    • C07C217/04—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated
    • C07C217/28—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having one amino group and at least two singly-bound oxygen atoms, with at least one being part of an etherified hydroxy group, bound to the carbon skeleton, e.g. ethers of polyhydroxy amines
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DK93923035T 1992-10-21 1993-10-18 2-Amino-1,3-propandiolforbindelser og immunundertrykkende midler DK0627406T3 (da)

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US5948820A (en) * 1994-08-22 1999-09-07 Yoshitomi Pharmaceutical Industries, Ltd. Benzene compound and pharmaceutical use thereof
ES2171191T3 (es) * 1994-08-22 2002-09-01 Mitsubishi Pharma Corp Compuesto de benceno y uso medicinal del mismo.
AU705320B2 (en) * 1995-12-28 1999-05-20 Welfide Corporation 2-amino-2-(2-(4-octylphenyl)ethyl)propane-1,3-diol or a pharmaceutically acceptable acid addition salt thereof for use in the preparation of a non-oral medicament, and for treatment of diseases and disorders
US6476004B1 (en) 1996-07-18 2002-11-05 Mitsubishi Pharma Corporation Pharmaceutical composition
JP2002241272A (ja) * 1996-07-18 2002-08-28 Mitsubishi Pharma Corp 医薬処方組成物
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JP2868887B2 (ja) * 1990-11-06 1999-03-10 花王株式会社 薬用化粧料
JPH04224548A (ja) * 1990-12-26 1992-08-13 Kao Corp 脂肪酸アミドの製造方法
AU664178B2 (en) * 1991-03-19 1995-11-09 Vithal J. Rajadhyaksha Compositions and method comprising aminoalcohol derivatives as membrane penetration enhancers
JPH0578294A (ja) * 1991-09-19 1993-03-30 Kao Corp 分岐脂肪酸アミド並びにその製造方法及び製造中間体

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EP0627406A4 (en) 1995-04-12
LU91832I2 (fr) 2011-08-30
CA2126337C (en) 2003-06-24
HK1013281A1 (en) 1999-08-20
EP0627406A1 (en) 1994-12-07
CA2126337A1 (en) 1994-04-28
US5952316A (en) 1999-09-14
KR0155015B1 (ko) 1998-12-01
CY2215B1 (en) 2003-04-18
CY2011006I1 (el) 2016-12-14
CY2011006I2 (el) 2016-12-14
DE122011100012I1 (de) 2011-10-20
DE69321823D1 (de) 1998-12-03
ES2126658T3 (es) 1999-04-01
KR940703803A (ko) 1994-12-12
ATE172711T1 (de) 1998-11-15
US5604229A (en) 1997-02-18
DE69321823T2 (de) 1999-06-02
WO1994008943A1 (en) 1994-04-28
JP2579602B2 (ja) 1997-02-05
EP0627406B1 (en) 1998-10-28
US5719176A (en) 1998-02-17

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