SG11201401330YA - Treatment of multiple sclerosis with combination of laquinimod and fingolimod - Google Patents
Treatment of multiple sclerosis with combination of laquinimod and fingolimodInfo
- Publication number
- SG11201401330YA SG11201401330YA SG11201401330YA SG11201401330YA SG11201401330YA SG 11201401330Y A SG11201401330Y A SG 11201401330YA SG 11201401330Y A SG11201401330Y A SG 11201401330YA SG 11201401330Y A SG11201401330Y A SG 11201401330YA SG 11201401330Y A SG11201401330Y A SG 11201401330YA
- Authority
- SG
- Singapore
- Prior art keywords
- laquinimod
- fingolimod
- treatment
- combination
- multiple sclerosis
- Prior art date
Links
Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/47—Quinolines; Isoquinolines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
- A61J1/00—Containers specially adapted for medical or pharmaceutical purposes
- A61J1/03—Containers specially adapted for medical or pharmaceutical purposes for pills or tablets
- A61J1/035—Blister-type containers
-
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/13—Amines
- A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
- A61K31/137—Arylalkylamines, e.g. amphetamine, epinephrine, salbutamol, ephedrine or methadone
-
- A—HUMAN NECESSITIES
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/47—Quinolines; Isoquinolines
- A61K31/4704—2-Quinolinones, e.g. carbostyril
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/02—Inorganic compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/26—Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
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- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
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- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
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- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
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- A—HUMAN NECESSITIES
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- A61P37/02—Immunomodulators
- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Medicinal Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Epidemiology (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Immunology (AREA)
- Neurology (AREA)
- Emergency Medicine (AREA)
- Biomedical Technology (AREA)
- Neurosurgery (AREA)
- Diabetes (AREA)
- Physical Education & Sports Medicine (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Rheumatology (AREA)
- Physiology (AREA)
- Biochemistry (AREA)
- Nutrition Science (AREA)
- Inorganic Chemistry (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Molecular Biology (AREA)
- Transplantation (AREA)
- Obesity (AREA)
- Dermatology (AREA)
- Endocrinology (AREA)
- Hematology (AREA)
- Psychiatry (AREA)
- Pain & Pain Management (AREA)
- Hospice & Palliative Care (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US201161546102P | 2011-10-12 | 2011-10-12 | |
PCT/US2012/059733 WO2013055907A1 (en) | 2011-10-12 | 2012-10-11 | Treatment of multiple sclerosis with combination of laquinimod and fingolimod |
Publications (1)
Publication Number | Publication Date |
---|---|
SG11201401330YA true SG11201401330YA (en) | 2014-05-29 |
Family
ID=48082429
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
SG11201401330YA SG11201401330YA (en) | 2011-10-12 | 2012-10-11 | Treatment of multiple sclerosis with combination of laquinimod and fingolimod |
Country Status (18)
Country | Link |
---|---|
US (4) | US8889627B2 (en) |
EP (1) | EP2766020A4 (en) |
JP (2) | JP2014530821A (en) |
KR (1) | KR20140101333A (en) |
CN (2) | CN103974704A (en) |
AR (1) | AR088458A1 (en) |
AU (2) | AU2012322706A1 (en) |
BR (1) | BR112014008731A2 (en) |
CA (1) | CA2851525A1 (en) |
EA (1) | EA201490748A1 (en) |
HK (1) | HK1199820A1 (en) |
IL (1) | IL231724A0 (en) |
MX (1) | MX2014004420A (en) |
SG (1) | SG11201401330YA (en) |
TW (1) | TW201321001A (en) |
UY (1) | UY34395A (en) |
WO (1) | WO2013055907A1 (en) |
ZA (1) | ZA201403378B (en) |
Families Citing this family (35)
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EP2234485B1 (en) | 2007-12-20 | 2013-11-13 | Teva Pharmaceutical Industries, Ltd. | Stable laquinimod preparations |
ES2586843T3 (en) * | 2009-08-10 | 2016-10-19 | Teva Pharmaceutical Industries Ltd. | Treatment of disorders related to BDNF using laquinimod |
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PL2498611T3 (en) | 2009-11-13 | 2018-07-31 | Celgene International Ii Sàrl | Sphingosine 1 phosphate receptor modulators and methods of chiral synthesis |
JP6129159B2 (en) | 2011-05-13 | 2017-05-17 | レセプトス エルエルシー | Selective heterocyclic sphingosine 1-phosphate receptor modulator |
MX2014004420A (en) * | 2011-10-12 | 2014-07-09 | Teva Pharma | Treatment of multiple sclerosis with combination of laquinimod and fingolimod. |
BR112014015940B1 (en) * | 2011-12-28 | 2022-08-09 | Galectin Therapeutics, Inc | PHARMACEUTICAL GRADE POLYSACCHARIDE, COMPOSITION, AND THEIR USES |
AR089862A1 (en) | 2012-02-03 | 2014-09-24 | Teva Pharma | USE OF LAQUINIMOD FOR THE TREATMENT OF PATIENTS WITH CROHN'S DISEASE IN THOSE WHO FAILS AN ANTI-FACTOR THUMOR NECROSIS THERAPY a (ANTI-TNFa) FIRST LINE |
JP6215238B2 (en) | 2012-02-16 | 2017-10-18 | テバ ファーマシューティカル インダストリーズ リミティド | N-ethyl-N-phenyl-1,2-dihydro-4,5-di-hydroxy-1-methyl-2-oxo-3-quinolinecarboxamide, its formulation and use |
TW201804997A (en) * | 2012-05-02 | 2018-02-16 | 以色列商泰瓦藥品工業有限公司 | Use of high dose LAQUINIMOD for treating multiple sclerosis |
TW201350467A (en) | 2012-05-08 | 2013-12-16 | Teva Pharma | N-ethyl-4-hydroxyl-1-methyl-5-(methyl(2,3,4,5,6-pentahydroxyhexyl)amino)-2-oxo-N-phenyl-1,2-dihydroquinoline-3-carboxamide |
TW201400117A (en) | 2012-06-05 | 2014-01-01 | Teva Pharma | Treatment of ocular inflammatory disease using laquinimod |
UY34896A (en) * | 2012-07-12 | 2014-02-28 | Teva Pharma | TREATMENT OF MULTIPLE SCLEROSIS WITH A COMBINATION OF LAQUINIMOD AND FAMPRIDINE |
TW201410244A (en) | 2012-08-13 | 2014-03-16 | Teva Pharma | Laquinimod for treatment of GABA mediated disorders |
AU2013329348A1 (en) * | 2012-10-12 | 2015-05-28 | Teva Pharmaceutical Industries Ltd. | Laquinimod for reducing thalamic damage in multiple sclerosis |
KR20150091077A (en) | 2012-11-07 | 2015-08-07 | 테바 파마슈티컬 인더스트리즈 리미티드 | Amine salts of laquinimod |
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JP2016527270A (en) * | 2013-07-31 | 2016-09-08 | テバ ファーマシューティカル インダストリーズ リミティド | Treatment of multiple sclerosis with a combination of laquinimod and flupirtine |
US20170165236A1 (en) * | 2013-11-01 | 2017-06-15 | Celgene International Ii Sàrl | Selective sphingosine 1 phosphate receptor modulators and combination therapy therewith |
AR098832A1 (en) * | 2013-12-20 | 2016-06-15 | Teva Pharma | USE OF LAQUINIMOD TO DELAY THE PROGRESSION OF HUNTINGTON'S DISEASE |
AR098924A1 (en) * | 2013-12-23 | 2016-06-22 | Teva Pharma | TREATMENT OF MULTIPLE SCLEROSIS WITH A COMBINATION OF LAQUINIMOD AND TERIFLUNOMIDE |
AU2015253330A1 (en) | 2014-04-29 | 2016-12-01 | Teva Pharmaceutical Industries Ltd. | Laquinimod for the treatment of relapsing-remitting multiple sclerosis (RRMS) patients with a high disability status |
EP3193870A4 (en) * | 2014-09-16 | 2018-04-25 | Teva Pharmaceutical Industries Ltd. | Treatment of neurodegenerative diseases with combination of laquinimod and fingolimod |
KR20170068480A (en) * | 2014-10-16 | 2017-06-19 | 노파르티스 아게 | Combinations comprising siponimod and laquinimod for the treatment of multiple sclerosis |
WO2016075543A1 (en) * | 2014-11-13 | 2016-05-19 | Teva Pharmaceutical Industries Ltd. | Treatment of multiple sclerosis with combination of laquinimod and a phosphodiesterase-4 (pde4) inhibitor |
EP3229786A4 (en) * | 2014-12-10 | 2018-07-04 | Teva Pharmaceutical Industries Ltd. | Treatment of multiple sclerosis with combination of laquinimod and a statin |
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WO2021158847A1 (en) * | 2020-02-07 | 2021-08-12 | Argentum Pharmaceuticals Llc | Treatment and dosing regimen for s1p receptor modulator |
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-
2012
- 2012-10-11 MX MX2014004420A patent/MX2014004420A/en unknown
- 2012-10-11 US US13/650,060 patent/US8889627B2/en not_active Expired - Fee Related
- 2012-10-11 EA EA201490748A patent/EA201490748A1/en unknown
- 2012-10-11 BR BR112014008731A patent/BR112014008731A2/en not_active IP Right Cessation
- 2012-10-11 EP EP12840715.2A patent/EP2766020A4/en not_active Withdrawn
- 2012-10-11 CN CN201280057918.9A patent/CN103974704A/en active Pending
- 2012-10-11 KR KR1020147012601A patent/KR20140101333A/en not_active Application Discontinuation
- 2012-10-11 AU AU2012322706A patent/AU2012322706A1/en not_active Abandoned
- 2012-10-11 SG SG11201401330YA patent/SG11201401330YA/en unknown
- 2012-10-11 WO PCT/US2012/059733 patent/WO2013055907A1/en active Application Filing
- 2012-10-11 CN CN201610629442.1A patent/CN106344576A/en active Pending
- 2012-10-11 JP JP2014535874A patent/JP2014530821A/en not_active Withdrawn
- 2012-10-11 CA CA2851525A patent/CA2851525A1/en not_active Abandoned
- 2012-10-12 UY UY0001034395A patent/UY34395A/en not_active Application Discontinuation
- 2012-10-12 TW TW101137835A patent/TW201321001A/en unknown
- 2012-10-12 AR ARP120103829A patent/AR088458A1/en unknown
-
2014
- 2014-03-26 IL IL231724A patent/IL231724A0/en unknown
- 2014-05-12 ZA ZA2014/03378A patent/ZA201403378B/en unknown
- 2014-10-21 US US14/520,145 patent/US20150037263A1/en not_active Abandoned
-
2015
- 2015-01-12 HK HK15100287.5A patent/HK1199820A1/en unknown
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2016
- 2016-06-10 US US15/179,800 patent/US20160279118A1/en not_active Abandoned
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2017
- 2017-01-18 JP JP2017006394A patent/JP2017137298A/en active Pending
- 2017-07-31 US US15/665,061 patent/US20170333418A1/en not_active Abandoned
- 2017-08-09 AU AU2017213497A patent/AU2017213497A1/en not_active Abandoned
Also Published As
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BR112014008731A2 (en) | 2017-04-25 |
HK1199820A1 (en) | 2015-07-24 |
EP2766020A1 (en) | 2014-08-20 |
CA2851525A1 (en) | 2013-04-18 |
IL231724A0 (en) | 2014-05-28 |
CN106344576A (en) | 2017-01-25 |
US20160279118A1 (en) | 2016-09-29 |
KR20140101333A (en) | 2014-08-19 |
AU2012322706A1 (en) | 2014-05-22 |
CN103974704A (en) | 2014-08-06 |
ZA201403378B (en) | 2015-07-29 |
TW201321001A (en) | 2013-06-01 |
EA201490748A1 (en) | 2014-12-30 |
AU2017213497A1 (en) | 2017-08-31 |
US20150037263A1 (en) | 2015-02-05 |
US8889627B2 (en) | 2014-11-18 |
JP2014530821A (en) | 2014-11-20 |
AR088458A1 (en) | 2014-06-11 |
UY34395A (en) | 2013-05-31 |
EP2766020A4 (en) | 2015-04-01 |
MX2014004420A (en) | 2014-07-09 |
US20130096158A1 (en) | 2013-04-18 |
WO2013055907A1 (en) | 2013-04-18 |
JP2017137298A (en) | 2017-08-10 |
US20170333418A1 (en) | 2017-11-23 |
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