EP0401384B1
(en)
*
|
1988-12-22 |
1996-03-13 |
Kirin-Amgen, Inc. |
Chemically modified granulocyte colony stimulating factor
|
DE59010941D1
(de)
*
|
1989-04-21 |
2005-03-24 |
Amgen Inc |
TNF-Rezeptor, TNF bindende Proteine und dafür kodierende DNAs
|
US7264944B1
(en)
|
1989-04-21 |
2007-09-04 |
Amgen Inc. |
TNF receptors, TNF binding proteins and DNAs coding for them
|
US6143866A
(en)
*
|
1989-07-18 |
2000-11-07 |
Amgen, Inc. |
Tumor necrosis factor (TNF) inhibitor and method for obtaining the same
|
IL95031A
(en)
|
1989-07-18 |
2007-03-08 |
Amgen Inc |
A method of producing a recombinant human necrotic factor absorber
|
US6552170B1
(en)
*
|
1990-04-06 |
2003-04-22 |
Amgen Inc. |
PEGylation reagents and compounds formed therewith
|
US5595732A
(en)
*
|
1991-03-25 |
1997-01-21 |
Hoffmann-La Roche Inc. |
Polyethylene-protein conjugates
|
US5880131A
(en)
*
|
1993-10-20 |
1999-03-09 |
Enzon, Inc. |
High molecular weight polymer-based prodrugs
|
US5919455A
(en)
|
1993-10-27 |
1999-07-06 |
Enzon, Inc. |
Non-antigenic branched polymer conjugates
|
DK0730470T3
(da)
*
|
1993-11-10 |
2002-06-03 |
Enzon Inc |
Forbedrede interferonpolymerkonjugater
|
US5951974A
(en)
*
|
1993-11-10 |
1999-09-14 |
Enzon, Inc. |
Interferon polymer conjugates
|
WO1995021629A1
(en)
*
|
1994-02-08 |
1995-08-17 |
Amgen Inc. |
Oral delivery of chemically modified proteins
|
US5730990A
(en)
*
|
1994-06-24 |
1998-03-24 |
Enzon, Inc. |
Non-antigenic amine derived polymers and polymer conjugates
|
US20030053982A1
(en)
*
|
1994-09-26 |
2003-03-20 |
Kinstler Olaf B. |
N-terminally chemically modified protein compositions and methods
|
DE4435087A1
(de)
*
|
1994-09-30 |
1996-04-04 |
Deutsches Krebsforsch |
Konjugat zur Behandlung von Infektions-, Autoimmun- und Hauterkrankungen
|
US5824784A
(en)
*
|
1994-10-12 |
1998-10-20 |
Amgen Inc. |
N-terminally chemically modified protein compositions and methods
|
US5738846A
(en)
*
|
1994-11-10 |
1998-04-14 |
Enzon, Inc. |
Interferon polymer conjugates and process for preparing the same
|
TW426523B
(en)
*
|
1995-04-06 |
2001-03-21 |
Hoffmann La Roche |
Interferon solution
|
DE19514087A1
(de)
*
|
1995-04-13 |
1996-10-17 |
Deutsches Krebsforsch |
Konjugat aus einem Wirkstoff, einem Polyether und ggfs. einem nicht als körperfremd angesehenen, nativen Protein
|
US5908621A
(en)
|
1995-11-02 |
1999-06-01 |
Schering Corporation |
Polyethylene glycol modified interferon therapy
|
JP2000507917A
(ja)
|
1995-11-02 |
2000-06-27 |
シェーリング コーポレイション |
持続的低用量サイトカイン注入治療
|
TW517067B
(en)
*
|
1996-05-31 |
2003-01-11 |
Hoffmann La Roche |
Interferon conjugates
|
TW555765B
(en)
*
|
1996-07-09 |
2003-10-01 |
Amgen Inc |
Low molecular weight soluble tumor necrosis factor type-I and type-II proteins
|
US20080076706A1
(en)
|
1997-07-14 |
2008-03-27 |
Bolder Biotechnology, Inc. |
Derivatives of Growth Hormone and Related Proteins, and Methods of Use Thereof
|
US7270809B2
(en)
*
|
1997-07-14 |
2007-09-18 |
Bolder Biotechnology, Inc. |
Cysteine variants of alpha interferon-2
|
US6753165B1
(en)
*
|
1999-01-14 |
2004-06-22 |
Bolder Biotechnology, Inc. |
Methods for making proteins containing free cysteine residues
|
US7495087B2
(en)
|
1997-07-14 |
2009-02-24 |
Bolder Biotechnology, Inc. |
Cysteine muteins in the C-D loop of human interleukin-11
|
EP1881005B1
(en)
*
|
1997-07-14 |
2013-04-03 |
Bolder Biotechnology, Inc. |
Derivatives of G-CSF and related proteins
|
CN1276730A
(zh)
*
|
1997-09-18 |
2000-12-13 |
霍夫曼-拉罗奇有限公司 |
α-干扰素和金刚胺用于治疗慢性丙型肝炎的应用
|
US6180095B1
(en)
*
|
1997-12-17 |
2001-01-30 |
Enzon, Inc. |
Polymeric prodrugs of amino- and hydroxyl-containing bioactive agents
|
WO1999030727A1
(en)
|
1997-12-17 |
1999-06-24 |
Enzon, Inc. |
Polymeric prodrugs of amino- and hydroxyl-containing bioactive agents
|
US5985263A
(en)
*
|
1997-12-19 |
1999-11-16 |
Enzon, Inc. |
Substantially pure histidine-linked protein polymer conjugates
|
US5981709A
(en)
*
|
1997-12-19 |
1999-11-09 |
Enzon, Inc. |
α-interferon-polymer-conjugates having enhanced biological activity and methods of preparing the same
|
FR2774687B1
(fr)
*
|
1998-02-06 |
2002-03-22 |
Inst Nat Sante Rech Med |
Lipopeptides contenant un fragment de l'interferon gamma, et leur utilisation dans des compositions pharmaceutiques
|
EP1066059B1
(en)
*
|
1998-03-26 |
2005-06-15 |
Schering Corporation |
Formulations for protection of peg-interferon alpha conjugates
|
US6180096B1
(en)
|
1998-03-26 |
2001-01-30 |
Schering Corporation |
Formulations for protection of peg-interferon alpha conjugates
|
CN1187094C
(zh)
*
|
1998-04-28 |
2005-02-02 |
应用研究系统Ars股份公司 |
多元醇干扰素β偶联物
|
JP5281726B2
(ja)
|
1998-05-15 |
2013-09-04 |
メルク・シャープ・アンド・ドーム・コーポレーション |
慢性C型肝炎感染を有する、抗ウイルス処置を受けていない患者における、リバビリンおよびインターフェロンαを含む併用療法
|
CA2330611A1
(en)
*
|
1998-05-22 |
1999-12-02 |
The Board Of Trustees Of The Leland Stanford Junior University |
Bifunctional molecules and therapies based thereon
|
ITMI981148A1
(it)
*
|
1998-05-22 |
1999-11-22 |
Therapicon Srl |
Utilizzo di lisozima c modificato per preparare composizioni medicinali per il trattamento di alcune gravi malattie
|
TR200003635T2
(tr)
*
|
1998-06-08 |
2001-04-20 |
F.Hoffmann-La Roche Ag |
Peg-IFN-ALFA ve ribavirinin kronik hepatit C tedavisinde kullanılması.
|
MXPA00012586A
(es)
*
|
1998-06-16 |
2004-05-21 |
Univ Oklahoma |
Glicosulfopeptidos y metodos de sintesis y uso de los mismos.
|
US7223845B2
(en)
|
1998-06-16 |
2007-05-29 |
The Board Of Regents Of The University Of Oklahoma |
Synthetic glycosulfopeptides and methods of synthesis thereof
|
US20030143662A1
(en)
*
|
1998-06-16 |
2003-07-31 |
Cummings Richard D. |
Glycosulfopeptide inhibitors of leukocyte rolling and methods of use thereof
|
AU762616B2
(en)
|
1998-10-16 |
2003-07-03 |
Biogen Ma Inc. |
Polymer conjugates of interferon beta-1a and uses
|
PL200586B1
(pl)
*
|
1998-10-16 |
2009-01-30 |
Biogen Idec Inc |
Polipeptydy zawierające mutanty interferonu-beta-1a, kodujące je cząsteczki kwasów nukleinowych, komórki gospodarza transformowane tymi cząsteczkami, sposób wytwarzania polipeptydów, zawierające je kompozycje farmaceutyczne i zastosowania polipeptydów
|
US6660843B1
(en)
*
|
1998-10-23 |
2003-12-09 |
Amgen Inc. |
Modified peptides as therapeutic agents
|
BR122013003013B8
(pt)
|
1999-01-14 |
2021-07-06 |
Bolder Biotechnology Inc |
proteína isolada monopeguilada do hormônio do crescimento e método para sua obtenção
|
US8288126B2
(en)
|
1999-01-14 |
2012-10-16 |
Bolder Biotechnology, Inc. |
Methods for making proteins containing free cysteine residues
|
ATE246202T1
(de)
*
|
1999-01-29 |
2003-08-15 |
Hoffmann La Roche |
Gcsf konjugate
|
US6605273B2
(en)
|
1999-04-08 |
2003-08-12 |
Schering Corporation |
Renal cell carcinoma treatment
|
US6362162B1
(en)
|
1999-04-08 |
2002-03-26 |
Schering Corporation |
CML Therapy
|
US6923966B2
(en)
|
1999-04-08 |
2005-08-02 |
Schering Corporation |
Melanoma therapy
|
BR0009646A
(pt)
|
1999-04-08 |
2002-02-05 |
Schering Corp |
Terapia de melanoma
|
PE20010288A1
(es)
|
1999-07-02 |
2001-03-07 |
Hoffmann La Roche |
Derivados de eritropoyetina
|
ES2364086T3
(es)
|
1999-07-07 |
2011-08-24 |
Zymogenetics, Inc. |
Receptor de citoquina humana.
|
WO2001005819A1
(en)
*
|
1999-07-15 |
2001-01-25 |
Kuhnil Pharm. Co., Ltd. |
Novel water soluble-cyclosporine conjugated compounds
|
US7431921B2
(en)
*
|
2000-04-14 |
2008-10-07 |
Maxygen Aps |
Interferon beta-like molecules
|
US6531122B1
(en)
*
|
1999-08-27 |
2003-03-11 |
Maxygen Aps |
Interferon-β variants and conjugates
|
US7144574B2
(en)
*
|
1999-08-27 |
2006-12-05 |
Maxygen Aps |
Interferon β variants and conjugates
|
US6969524B1
(en)
|
1999-10-12 |
2005-11-29 |
Santen Pharamceutical Co., Ltd. |
Interferon complex and medicinal use thereof
|
CA2390292A1
(en)
|
1999-11-12 |
2001-05-25 |
Maxygen Holdings Ltd. |
Interferon gamma conjugates
|
CN1309423C
(zh)
|
1999-11-12 |
2007-04-11 |
马克西根控股公司 |
干扰素γ偶联物
|
US7220552B1
(en)
|
1999-11-19 |
2007-05-22 |
The Board Of Trustees Of The Leland Stanford Junior University |
Bifunctional molecules and their use in the disruption of protein-protein interactions
|
EP1229924A4
(en)
|
1999-11-19 |
2004-12-15 |
Univ Leland Stanford Junior |
TARGETED BIFUNCTIONAL MOLECULES AND THERAPIES THEREFORE
|
US6887842B1
(en)
*
|
1999-11-19 |
2005-05-03 |
The Board Of Trustees Of The Leland Stanford Junior University |
Modulating a pharmacokinetic property of a drug by administering a bifunctional molecule containing the drug
|
US6897292B2
(en)
|
1999-12-03 |
2005-05-24 |
Zymogenetics, Inc. |
Human cytokine receptor
|
CN1188172C
(zh)
|
2000-01-10 |
2005-02-09 |
马克西根控股公司 |
G-csf偶联物
|
US20020009428A1
(en)
*
|
2000-01-24 |
2002-01-24 |
Zaknoen Sara L. |
Combination therapy for cancer
|
EP1908477A3
(en)
*
|
2000-01-24 |
2008-06-11 |
Schering Corporation |
Combination of temozolomide and pegylated interferon-alpha for treating cancer
|
RU2278123C2
(ru)
|
2000-02-11 |
2006-06-20 |
Максиджен Холдингз Лтд. |
Молекулы, подобные фактору vii или viia
|
KR100353392B1
(ko)
*
|
2000-03-13 |
2002-09-18 |
선바이오(주) |
높은 생체 활성도를 갖는 생체 활성 단백질과 peg의결합체 제조방법
|
US6777387B2
(en)
|
2000-03-31 |
2004-08-17 |
Enzon Pharmaceuticals, Inc. |
Terminally-branched polymeric linkers containing extension moieties and polymeric conjugates containing the same
|
US6756037B2
(en)
|
2000-03-31 |
2004-06-29 |
Enzon, Inc. |
Polymer conjugates of biologically active agents and extension moieties for facilitating conjugation of biologically active agents to polymeric terminal groups
|
DE60137525D1
(de)
*
|
2000-10-16 |
2009-03-12 |
Chugai Pharmaceutical Co Ltd |
Peg-modifiziertes erythropoietin
|
US20020169290A1
(en)
*
|
2000-11-02 |
2002-11-14 |
Claus Bornaes |
New multimeric interferon beta polypeptides
|
US20030092164A1
(en)
|
2000-11-07 |
2003-05-15 |
Gross Jane A. |
Human tumor necrosis factor receptor
|
EP2301971A1
(en)
|
2001-02-20 |
2011-03-30 |
ZymoGenetics, L.L.C. |
Antibodies that bind both BCMA and TACI
|
MXPA03007392A
(es)
*
|
2001-02-20 |
2003-12-04 |
Enzon Inc |
Enlazantes polimericos ramificados terminalmente y conjugados polimericos que contienen los mismos.
|
MXPA03007619A
(es)
|
2001-02-27 |
2003-12-04 |
Maxygen Aps |
Nuevas moleculas similares a interferon beta.
|
CA2439636A1
(en)
|
2001-03-02 |
2002-09-12 |
Zymogenetics, Inc. |
Mouse cytokine receptor
|
US6958388B2
(en)
|
2001-04-06 |
2005-10-25 |
Maxygen, Aps |
Interferon gamma polypeptide variants
|
US7038015B2
(en)
*
|
2001-04-06 |
2006-05-02 |
Maxygen Holdings, Ltd. |
Interferon gamma polypeptide variants
|
WO2002083166A1
(fr)
*
|
2001-04-10 |
2002-10-24 |
Santen Pharmaceutical Co., Ltd. |
Complexes de polymeres d'interferons et leur utilisation medicinale
|
RS20120253A1
(en)
|
2001-05-24 |
2013-02-28 |
Zymogenetics Inc. |
TACI-IMUNOGLOBULINSKI PROTEIN FUNCTIONS
|
JP4142569B2
(ja)
*
|
2001-06-22 |
2008-09-03 |
協和醗酵工業株式会社 |
軟膏剤
|
MD2053C2
(ro)
*
|
2001-07-10 |
2003-07-31 |
Национальный Научно-Практический Центр Превентивной Медицины Министерства Здравоохранения Республики Молдова |
Remediu cu acţiune interferonogenă
|
DE60223047T2
(de)
|
2001-08-22 |
2008-07-24 |
Bioartificial Gel Technologies Inc., Montreal |
Verfahren zur herstellung von aktivierten polyethylenglykolen
|
US20050095224A1
(en)
*
|
2001-12-07 |
2005-05-05 |
Ramachandran Radhakrishnan |
Compositions and method for treating hepatitis virus infection
|
KR100888371B1
(ko)
|
2002-01-17 |
2009-03-13 |
동아제약주식회사 |
가지 달린 고분자 유도체와 인터페론 결합체를 포함하는 항바이러스제
|
GEP20074024B
(en)
|
2002-01-18 |
2007-01-10 |
Biogen Idec Inc |
Polyalkylene glycol comprising a radical for conjugation of biologically active compound
|
US8003089B2
(en)
*
|
2002-03-13 |
2011-08-23 |
Beijing Jiankai Technology Co., Ltd. |
Y shape branched hydrophilic polymer derivatives, their preparation methods, conjugates of the derivatives and drug molecules, and pharmaceutical compositions comprising the conjugates
|
EP1496925A4
(en)
*
|
2002-04-11 |
2007-05-30 |
Zymogenetics Inc |
USE OF INTERLEUKIN-24 FOR THE TREATMENT OF OVARIAL CARCINOMA
|
EP1497415B1
(en)
|
2002-04-19 |
2010-12-29 |
ZymoGenetics, L.L.C. |
Methods for detection or modulation of the interaction of a cytokine receptor with its ligand
|
AU2003240439B2
(en)
|
2002-06-21 |
2009-05-21 |
Novo Nordisk Health Care Ag |
Pegylated factor VII glycoforms
|
AU2003239774A1
(en)
*
|
2002-07-03 |
2004-01-23 |
Maxygen Holdings Ltd. |
Full-length interferon gamma polypeptide variants
|
KR100608415B1
(ko)
*
|
2002-07-24 |
2006-08-02 |
에프. 호프만-라 로슈 아게 |
폴리알킬렌 글리콜산 첨가제
|
JP2006508918A
(ja)
*
|
2002-09-05 |
2006-03-16 |
ザ ジェネラル ホスピタル コーポレーション |
修飾されたアシアロインターフェロンおよびその使用
|
AU2003268463A1
(en)
*
|
2002-09-05 |
2004-03-29 |
The General Hospital Corporation |
Asialo-interferons and the treatment of liver cancer
|
JP4237703B2
(ja)
*
|
2002-09-27 |
2009-03-11 |
エフ.ホフマン−ラ ロシュ アーゲー |
インスリン様成長因子結合タンパク質−4及びポリ(エチレングリコール)の接合体
|
US20040175359A1
(en)
*
|
2002-11-12 |
2004-09-09 |
Desjarlais John Rudolph |
Novel proteins with antiviral, antineoplastic, and/or immunomodulatory activity
|
US7314613B2
(en)
*
|
2002-11-18 |
2008-01-01 |
Maxygen, Inc. |
Interferon-alpha polypeptides and conjugates
|
RS20050501A
(en)
*
|
2002-12-26 |
2007-08-03 |
Mountain View Pharmaceuticals Inc., |
Polymer conjugates of cytokines,chemokines,growth factors, polypeptide hormones and antagonists thereof with preserved receptor-binding activity
|
WO2004060299A2
(en)
*
|
2002-12-26 |
2004-07-22 |
Mountain View Pharmaceuticals, Inc. |
Polymer conjugates of interferon-beta with enhanced biological potency
|
KR101090784B1
(ko)
*
|
2002-12-31 |
2011-12-08 |
넥타르 테라퓨틱스 |
케톤 또는 관련 관능기를 함유하는 중합체성 시약
|
CA2515612A1
(en)
*
|
2003-02-19 |
2004-09-02 |
Pharmacia Corporation |
Activated polyethylene glycol esters
|
JP2006519235A
(ja)
*
|
2003-02-26 |
2006-08-24 |
インターミューン インコーポレイティッド |
ポリエチレングリコール修飾インターフェロン組成物およびその使用方法
|
WO2004078127A2
(en)
*
|
2003-02-28 |
2004-09-16 |
Intermune, Inc. |
Continuous delivery methods for treating hepatitis virus infection
|
CA2458085A1
(en)
|
2003-03-21 |
2004-09-21 |
F. Hoffmann-La Roche Ag |
Transcriptional activity assay
|
US20070172446A1
(en)
|
2003-05-16 |
2007-07-26 |
Intermune, Inc. |
Synthetic chemokine receptor ligands and methods of use thereof
|
ATE388963T1
(de)
|
2003-08-07 |
2008-03-15 |
Zymogenetics Inc |
Homogene herstellungen von il-29
|
GB0320638D0
(en)
|
2003-09-03 |
2003-10-01 |
Novartis Ag |
Organic compounds
|
ATE481420T1
(de)
|
2003-10-10 |
2010-10-15 |
Novo Nordisk As |
Il-21-derivate
|
DK1680137T3
(da)
|
2003-10-14 |
2013-02-18 |
Hoffmann La Roche |
Makrocyklisk carboxylsyre- og acylsulfonamidforbindelse som inhibitor af HCV-replikation
|
ES2428358T3
(es)
|
2003-10-17 |
2013-11-07 |
Novo Nordisk A/S |
Terapia de combinación
|
US20050089952A1
(en)
*
|
2003-10-22 |
2005-04-28 |
Akzo Nobel N.V. |
Apparatuses and processes for increasing protein PEGylation reaction yields
|
US7407973B2
(en)
*
|
2003-10-24 |
2008-08-05 |
Intermune, Inc. |
Use of pirfenidone in therapeutic regimens
|
WO2005062949A2
(en)
*
|
2003-12-23 |
2005-07-14 |
Intermune, Inc. |
Method for treating hepatitis virus infection
|
GB0500020D0
(en)
|
2005-01-04 |
2005-02-09 |
Novartis Ag |
Organic compounds
|
AU2005211385B2
(en)
*
|
2004-02-02 |
2008-12-11 |
Ambrx, Inc. |
Modified human growth hormone polypeptides and their uses
|
US7351787B2
(en)
*
|
2004-03-05 |
2008-04-01 |
Bioartificial Gel Technologies, Inc. |
Process for the preparation of activated polyethylene glycols
|
MXPA06013412A
(es)
*
|
2004-05-19 |
2007-01-23 |
Maxygen Inc |
Polipeptidos de interferon-alfa y conjugados.
|
WO2005123113A2
(en)
*
|
2004-06-14 |
2005-12-29 |
Intermune, Inc. |
Interferon compositions and methods of use thereof
|
WO2006009901A2
(en)
*
|
2004-06-18 |
2006-01-26 |
Ambrx, Inc. |
Novel antigen-binding polypeptides and their uses
|
US7638299B2
(en)
*
|
2004-07-21 |
2009-12-29 |
Ambrx, Inc. |
Biosynthetic polypeptides utilizing non-naturally encoded amino acids
|
WO2006012644A2
(en)
|
2004-07-29 |
2006-02-02 |
Zymogenetics, Inc. |
Use of il-28 and il-29 to treat cancer
|
DE602005022895D1
(de)
|
2004-08-12 |
2010-09-23 |
Schering Corp |
Stabile pegylierte interferon-formulierung
|
ES2529451T3
(es)
|
2004-09-23 |
2015-02-20 |
Vasgene Therapeutics, Inc. |
Compuestos polipeptídicos para inhibir la angiogénesis y el crecimiento tumoral
|
MX2007007591A
(es)
*
|
2004-12-22 |
2007-07-25 |
Ambrx Inc |
Metodos para expresion y purificacion de hormona de crecimiento humano recombinante.
|
ATE542920T1
(de)
*
|
2004-12-22 |
2012-02-15 |
Ambrx Inc |
Modifiziertes menschliches wachstumshormon
|
US7816320B2
(en)
|
2004-12-22 |
2010-10-19 |
Ambrx, Inc. |
Formulations of human growth hormone comprising a non-naturally encoded amino acid at position 35
|
EP1836298B1
(en)
*
|
2004-12-22 |
2012-01-18 |
Ambrx, Inc. |
COMPOSITIONS OF AMINOACYL-tRNA SYNTHETASE AND USES THEREOF
|
EP2192132A3
(en)
|
2005-02-08 |
2010-08-18 |
ZymoGenetics, Inc. |
Anti-IL-20, anti-IL22 and anti-IL-22RA antibodies and binding partners and methods of using in inflammation
|
ES2772674T3
(es)
|
2005-05-12 |
2020-07-08 |
Zymogenetics Inc |
Composiciones y métodos para modular respuestas inmunitarias
|
JP2008545393A
(ja)
*
|
2005-05-18 |
2008-12-18 |
マキシジェン, インコーポレイテッド |
進歩したインターフェロンαポリペプチド
|
CN103030690A
(zh)
*
|
2005-06-03 |
2013-04-10 |
Ambrx公司 |
经改良人类干扰素分子和其用途
|
US20090042790A1
(en)
*
|
2005-06-13 |
2009-02-12 |
Nastech Pharmaceutical Company Inc. |
Transmucosal delivery of peptide derivatives
|
AU2006259348B2
(en)
|
2005-06-17 |
2010-07-22 |
Novartis Ag |
Use of sanglifehrin in HCV
|
WO2006134173A2
(en)
|
2005-06-17 |
2006-12-21 |
Novo Nordisk Health Care Ag |
Selective reduction and derivatization of engineered proteins comprising at least one non-native cysteine
|
EP1901777A2
(en)
*
|
2005-06-20 |
2008-03-26 |
Pepgen Corporation |
Low-toxicity, long-circulating chimeras of human interferon-alpha analogs and interferon tau
|
US7695710B2
(en)
|
2005-06-20 |
2010-04-13 |
Pepgen Corporation |
Antitumor and antiviral combination therapies using low-toxicity, long-circulating human interferon-alpha analogs
|
ES2435846T3
(es)
*
|
2005-06-29 |
2013-12-23 |
Yeda Research And Development Co. Ltd. |
Mutantes de Interferón alfa 2 (IFN alfa 2) recombinante
|
JP5249028B2
(ja)
|
2005-07-25 |
2013-07-31 |
インターミューン・インコーポレーテッド |
C型肝炎ウイルス複製の新規大環状阻害剤
|
KR101285904B1
(ko)
*
|
2005-08-18 |
2013-07-15 |
암브룩스, 인코포레이티드 |
tRNA 조성물 및 이의 용도
|
AU2006294511B2
(en)
|
2005-09-28 |
2011-11-17 |
Zymogenetics, Inc |
IL-17A and IL-17F antagonists and methods of using the same
|
DE602006019323D1
(de)
|
2005-10-11 |
2011-02-10 |
Intermune Inc |
Verbindungen und verfahren zur inhibierung der replikation des hepatitis-c-virus
|
US20080171696A1
(en)
*
|
2005-10-21 |
2008-07-17 |
Avigenics, Inc. |
Pharmacodynamically enhanced therapeutic proteins
|
CN101291684A
(zh)
*
|
2005-10-21 |
2008-10-22 |
阿维季尼克斯股份有限公司 |
甘醇化和糖基化的禽类来源的治疗性蛋白
|
CN101400646A
(zh)
*
|
2005-11-08 |
2009-04-01 |
Ambrx公司 |
用于修饰非天然氨基酸和非天然氨基酸多肽的促进剂
|
US20090018029A1
(en)
*
|
2005-11-16 |
2009-01-15 |
Ambrx, Inc. |
Methods and Compositions Comprising Non-Natural Amino Acids
|
CN105384807A
(zh)
*
|
2005-12-14 |
2016-03-09 |
Ambrx公司 |
含有非天然氨基酸和多肽的组合物、涉及非天然氨基酸和多肽的方法以及非天然氨基酸和多肽的用途
|
WO2007080942A1
(ja)
|
2006-01-12 |
2007-07-19 |
The Kitasato Institute |
インターフェロンαを含む口腔組成物
|
CN100475270C
(zh)
|
2006-01-20 |
2009-04-08 |
清华大学 |
一种治疗肿瘤的药物及其应用
|
CN101002945B
(zh)
|
2006-01-20 |
2012-09-05 |
清华大学 |
一种用于肿瘤治疗的新型复合物
|
ES2543840T3
(es)
|
2006-04-11 |
2015-08-24 |
Novartis Ag |
Inhibidores espirocíclicos del VHC/VIH y sus usos
|
EP2018437A2
(en)
*
|
2006-05-02 |
2009-01-28 |
Allozyne, Inc. |
Non-natural amino acid substituted polypeptides
|
US20080096819A1
(en)
*
|
2006-05-02 |
2008-04-24 |
Allozyne, Inc. |
Amino acid substituted molecules
|
CN104593348A
(zh)
|
2006-05-24 |
2015-05-06 |
诺沃—诺迪斯克保健股份有限公司 |
具有延长的体内半寿期的因子ix类似物
|
US7985734B2
(en)
|
2006-06-01 |
2011-07-26 |
Yun Cheng |
Peptides for preventing or treating liver damage
|
CN1911447B
(zh)
*
|
2006-06-30 |
2010-05-12 |
复旦大学 |
转铁蛋白-聚乙二醇-药物分子复合物及其制备药物的用途
|
EP1886685A1
(en)
|
2006-08-11 |
2008-02-13 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Methods, uses and compositions for modulating replication of hcv through the farnesoid x receptor (fxr) activation or inhibition
|
WO2008063727A2
(en)
*
|
2006-08-21 |
2008-05-29 |
United Therapeutics Corporation |
Combination therapy for treatment of viral infections
|
SG174781A1
(en)
*
|
2006-09-08 |
2011-10-28 |
Ambrx Inc |
Hybrid suppressor trna for vertebrate cells
|
JP5451390B2
(ja)
*
|
2006-09-08 |
2014-03-26 |
アンブルックス,インコーポレイテッド |
脊椎動物細胞内におけるサプレッサーtrnaの転写
|
AU2007292903B2
(en)
*
|
2006-09-08 |
2012-03-29 |
Ambrx, Inc. |
Modified human plasma polypeptide or Fc scaffolds and their uses
|
BRPI0719597A2
(pt)
|
2006-11-22 |
2013-12-17 |
Adnexus A Bristol Myers Squibb R & D Company |
Produtos terapêuticos objetivados baseados em proteínas manipuladas para receptores de quinases de tirosina, incluindo igf-ir
|
CN101219219B
(zh)
|
2007-01-10 |
2013-02-13 |
北京普罗吉生物科技发展有限公司 |
包含血管抑素或其片段的复合物、其制备方法及应用
|
US20100144599A1
(en)
|
2007-02-02 |
2010-06-10 |
Bristol-Myers Squibb Company |
Vegf pathway blockade
|
KR101476472B1
(ko)
*
|
2007-03-30 |
2015-01-05 |
암브룩스, 인코포레이티드 |
변형된 fgf-21 폴리펩티드 및 그 용도
|
CA2685596A1
(en)
*
|
2007-05-02 |
2008-11-13 |
Ambrx, Inc. |
Modified interferon beta polypeptides and their uses
|
CA2707840A1
(en)
|
2007-08-20 |
2009-02-26 |
Allozyne, Inc. |
Amino acid substituted molecules
|
ES2382124T3
(es)
|
2007-09-04 |
2012-06-05 |
Biosteed Gene Expression Tech. Co., Ltd. |
Interferón alfa 2b modificado con polietilenglicol y método de preparación y aplicaciones de este
|
DK2196475T3
(da)
*
|
2007-09-04 |
2012-09-17 |
Biosteed Gene Expression Tech Co Ltd |
Interferon alfa 2a, som er modificeret med polyethylenglycol, fremgangsmåde til syntese deraf samt anvendelse deraf
|
JP5496897B2
(ja)
|
2007-10-04 |
2014-05-21 |
ザイモジェネティクス, インコーポレイテッド |
B7ファミリーメンバーのzB7H6ならびに関連する組成物および方法
|
EP2212432A4
(en)
|
2007-10-22 |
2011-10-19 |
Schering Corp |
COMPLETELY HUMAN ANTI-VEGF ANTIBODIES AND USE PROCEDURES
|
NZ584825A
(en)
|
2007-11-20 |
2013-03-28 |
Ambrx Inc |
Modified insulin polypeptides and their uses
|
EP2796466B1
(en)
|
2007-12-07 |
2017-11-22 |
ZymoGenetics, Inc. |
Humanized antibody molecules specific for IL-31
|
JP5702150B2
(ja)
|
2008-02-08 |
2015-04-15 |
アンブルックス, インコーポレイテッドAmbrx, Inc. |
修飾されているレプチンポリペプチドおよびそれらの使用
|
MX2010010953A
(es)
|
2008-04-03 |
2011-04-21 |
Biosteed Gene Expression Tech Co Ltd |
Hormona de crecimiento modificada con glicol de polietileno de doble cadena, metodo de preparacion y aplicación del a misma.
|
JP2011520961A
(ja)
|
2008-05-22 |
2011-07-21 |
ブリストル−マイヤーズ スクイブ カンパニー |
多価フィブロネクチンをベースとする足場ドメインタンパク質
|
JP2011526154A
(ja)
|
2008-06-27 |
2011-10-06 |
ザイモジェネティクス, インコーポレイテッド |
可溶性ハイブリッドFcγレセプターおよび関連する方法
|
JP5680534B2
(ja)
|
2008-07-23 |
2015-03-04 |
イーライ リリー アンド カンパニー |
修飾されているウシg−csfポリペプチドおよびそれらの使用
|
PL2342223T3
(pl)
|
2008-09-26 |
2017-09-29 |
Ambrx, Inc. |
Zmodyfikowane polipeptydy zwierzęcej erytropoetyny i ich zastosowania
|
AU2009296267B2
(en)
|
2008-09-26 |
2013-10-31 |
Ambrx, Inc. |
Non-natural amino acid replication-dependent microorganisms and vaccines
|
EP3025727A1
(en)
|
2008-10-02 |
2016-06-01 |
The J. David Gladstone Institutes |
Methods of treating liver disease
|
EP2408449A4
(en)
|
2009-03-18 |
2012-08-08 |
Univ Leland Stanford Junior |
METHODS AND COMPOSITIONS FOR TREATING INFECTION WITH A FLAVIVIRIDAE FAMILY VIRUS
|
US8512690B2
(en)
|
2009-04-10 |
2013-08-20 |
Novartis Ag |
Derivatised proline containing peptide compounds as protease inhibitors
|
US20110182850A1
(en)
|
2009-04-10 |
2011-07-28 |
Trixi Brandl |
Organic compounds and their uses
|
PL2437785T3
(pl)
|
2009-06-04 |
2015-08-31 |
Novartis Ag |
Sposoby identyfikacji miejsc sprzęgania IgG
|
WO2011014882A1
(en)
|
2009-07-31 |
2011-02-03 |
Medtronic, Inc. |
CONTINUOUS SUBCUTANEOUS ADMINISTRATION OF INTERFERON-α TO HEPATITIS C INFECTED PATIENTS
|
KR20120106942A
(ko)
|
2009-10-30 |
2012-09-27 |
베링거 인겔하임 인터내셔날 게엠베하 |
Bi201335, 인터페론 알파 및 리바비린을 포함하는 hcv 병용 치료요법을 위한 투여 용법
|
CN107674121A
(zh)
|
2009-12-21 |
2018-02-09 |
Ambrx 公司 |
经过修饰的牛促生长素多肽和其用途
|
CN104017063A
(zh)
|
2009-12-21 |
2014-09-03 |
Ambrx公司 |
经过修饰的猪促生长素多肽和其用途
|
US20120135912A1
(en)
|
2010-05-10 |
2012-05-31 |
Perseid Therapeutics Llc |
Polypeptide inhibitors of vla4
|
US8362007B1
(en)
|
2010-05-11 |
2013-01-29 |
Demerx, Inc. |
Substituted noribogaine
|
US8765737B1
(en)
|
2010-05-11 |
2014-07-01 |
Demerx, Inc. |
Methods and compositions for preparing and purifying noribogaine
|
US9394294B2
(en)
|
2010-05-11 |
2016-07-19 |
Demerx, Inc. |
Methods and compositions for preparing and purifying noribogaine
|
US9562089B2
(en)
|
2010-05-26 |
2017-02-07 |
Bristol-Myers Squibb Company |
Fibronectin based scaffold proteins having improved stability
|
CN102711871A
(zh)
|
2010-06-16 |
2012-10-03 |
麦德托尼克公司 |
用于稳定药物递送装置中的药物的阻尼系统
|
US8802832B2
(en)
|
2010-06-22 |
2014-08-12 |
Demerx, Inc. |
Compositions comprising noribogaine and an excipient to facilitate transport across the blood brain barrier
|
US9586954B2
(en)
|
2010-06-22 |
2017-03-07 |
Demerx, Inc. |
N-substituted noribogaine prodrugs
|
US8637648B1
(en)
|
2010-06-22 |
2014-01-28 |
Demerx, Inc. |
Compositions comprising noribogaine and an excipient to facilitate transport across the blood brain barrier
|
US8741891B1
(en)
|
2010-06-22 |
2014-06-03 |
Demerx, Inc. |
N-substituted noribogaine prodrugs
|
EP2585065A1
(en)
|
2010-06-24 |
2013-05-01 |
Panmed Ltd. |
Treatment of hepatitis c virus related diseases using hydroxychloroquine or a combination of hydroxychloroquine and an anti-viral agent
|
WO2012012764A1
(en)
|
2010-07-23 |
2012-01-26 |
Demerx, Inc. |
Noribogaine compositions
|
MX346786B
(es)
|
2010-08-17 |
2017-03-31 |
Ambrx Inc |
Polipeptidos de relaxina modificados y sus usos.
|
US9567386B2
(en)
|
2010-08-17 |
2017-02-14 |
Ambrx, Inc. |
Therapeutic uses of modified relaxin polypeptides
|
AR083006A1
(es)
|
2010-09-23 |
2013-01-23 |
Lilly Co Eli |
Formulaciones para el factor estimulante de colonias de granulocitos (g-csf) bovino y variantes de las mismas
|
AU2011311706B2
(en)
|
2010-10-05 |
2015-11-12 |
Debiopharm S.A. |
New treatments of Hepatitis C virus infection
|
BR112013008510A2
(pt)
|
2010-10-08 |
2016-07-05 |
Novartis Ag |
vitamina e formulações de inibidores de sulfamida ns3
|
BR112013013166A2
(pt)
|
2010-11-30 |
2016-09-06 |
Novartis Ag |
tratamentos da infecção pelo vírus da hepatite c
|
EP2481740B1
(en)
|
2011-01-26 |
2015-11-04 |
DemeRx, Inc. |
Methods and compositions for preparing noribogaine from voacangine
|
WO2012107589A1
(en)
|
2011-02-11 |
2012-08-16 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Methods and pharmaceutical compositions for the treatment and prevention of hcv infections
|
BR112013025021A2
(pt)
|
2011-03-31 |
2017-03-01 |
Novartis Ag |
alisporivir para tratar infecções por vírus de hepatite c.
|
JP2014509630A
(ja)
|
2011-04-01 |
2014-04-21 |
ノバルティス アーゲー |
B型肝炎ウイルス単独の感染症またはデルタ肝炎ウイルスとの複合感染症および付随する肝疾患の治療
|
MX2013011941A
(es)
|
2011-04-13 |
2014-05-28 |
Debiopharm Int Sa |
Tratamiento de infeccion por el virus de hepatitis c con alisporivir.
|
EP2709669A1
(en)
|
2011-05-17 |
2014-03-26 |
Bristol-Myers Squibb Company |
Methods for maintaining pegylation of polypeptides
|
EP2709648A4
(en)
|
2011-05-19 |
2015-04-08 |
Geysen Hendrik M |
COMPOUNDS FOR BINDING TO THE ERYTHROPOIETIN RECEPTOR
|
MX2014000031A
(es)
|
2011-07-01 |
2014-07-09 |
Bayer Ip Gmbh |
Polipeptidos de fusion de relaxina y usos de los mismos.
|
WO2013011113A1
(en)
|
2011-07-20 |
2013-01-24 |
Inserm (Institut National De La Sante Et De La Recherche Medicale) |
Methods for determining treatment response in patients infected with hcv genotype 4
|
CA2846092A1
(en)
*
|
2011-08-25 |
2013-02-28 |
Nanogen Pharmaceutical Biotechnology |
Peg-interferon lambda 1 conjugates
|
US9617274B1
(en)
|
2011-08-26 |
2017-04-11 |
Demerx, Inc. |
Synthetic noribogaine
|
BR112014007247A2
(pt)
|
2011-09-27 |
2017-03-28 |
Novartis Ag |
alisporivir para o tratamento de infecção por vírus da hepatite c
|
US9522951B2
(en)
|
2011-10-31 |
2016-12-20 |
Bristol-Myers Squibb Company |
Fibronectin binding domains with reduced immunogenicity
|
MX349036B
(es)
|
2011-12-06 |
2017-07-07 |
Univ Leland Stanford Junior |
Metodos y composiciones para tratar enfermedades virales.
|
CA2855994A1
(en)
|
2011-12-09 |
2013-06-13 |
Demerx, Inc. |
Phosphate esters of noribogaine
|
CA2858820C
(en)
|
2012-01-25 |
2021-08-17 |
Demerx, Inc. |
Synthetic voacangine
|
US9150584B2
(en)
|
2012-01-25 |
2015-10-06 |
Demerx, Inc. |
Indole and benzofuran fused isoquinuclidene derivatives and processes for preparing them
|
US8454947B1
(en)
|
2012-03-01 |
2013-06-04 |
Nanogen Pharmaceutical Biotechnology |
PEG-interferon lambda 1 conjugates
|
WO2013137869A1
(en)
|
2012-03-14 |
2013-09-19 |
Boehringer Ingelheim International Gmbh |
Combination therapy for treating hcv infection in an hcv-hiv coinfected patient population
|
JP2015512900A
(ja)
|
2012-03-28 |
2015-04-30 |
ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング |
特別な患者の遺伝子亜型分集団のhcv感染症を治療するための併用療法
|
CN104411332B
(zh)
|
2012-03-30 |
2018-11-23 |
索伦托治疗有限公司 |
与vegfr2结合的全人抗体
|
WO2013177187A2
(en)
|
2012-05-22 |
2013-11-28 |
Massachusetts Institute Of Technology |
Synergistic tumor treatment with extended-pk il-2 and therapeutic agents
|
WO2013174988A1
(en)
|
2012-05-24 |
2013-11-28 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Methods for predicting and monitoring treatment response in hcv- and hcv/hiv-infected subjects
|
CN115093480A
(zh)
|
2012-05-31 |
2022-09-23 |
索伦托药业有限公司 |
与pd-l1结合的抗原结合蛋白
|
AU2013270684B2
(en)
|
2012-06-08 |
2018-04-19 |
Sutro Biopharma, Inc. |
Antibodies comprising site-specific non-natural amino acid residues, methods of their preparation and methods of their use
|
EP2863946A4
(en)
|
2012-06-21 |
2016-04-13 |
Sorrento Therapeutics Inc |
ANTIGEN-BINDING PROTEINS THAT BIND TO C-MET
|
US9315579B2
(en)
|
2012-06-22 |
2016-04-19 |
Sorrento Therapeutics, Inc. |
Antigen binding proteins that bind CCR2
|
DK2863955T3
(en)
|
2012-06-26 |
2017-01-23 |
Sutro Biopharma Inc |
MODIFIED FC PROTEINS, INCLUDING LOCATION-SPECIFIC NON-NATURAL AMINO ACID RESIDUES, CONJUGATES THEREOF, METHODS OF PRODUCING ITS AND PROCEDURES FOR USE THEREOF
|
EP4074728A1
(en)
|
2012-08-31 |
2022-10-19 |
Sutro Biopharma, Inc. |
Modified peptides comprising an azido group
|
US20140205566A1
(en)
|
2012-11-30 |
2014-07-24 |
Novartis Ag |
Cyclic nucleuoside derivatives and uses thereof
|
US9045481B2
(en)
|
2012-12-20 |
2015-06-02 |
Demerx, Inc. |
Substituted noribogaine
|
US8940728B2
(en)
|
2012-12-20 |
2015-01-27 |
Demerx, Inc. |
Substituted noribogaine
|
CA2896133A1
(en)
|
2012-12-20 |
2014-06-26 |
Demerx, Inc. |
Substituted noribogaine
|
US20150361159A1
(en)
|
2013-02-01 |
2015-12-17 |
Bristol-Myers Squibb Company |
Fibronectin based scaffold proteins
|
JP6563906B2
(ja)
|
2013-05-31 |
2019-08-21 |
ソレント・セラピューティクス・インコーポレイテッドSorrento Therapeutics, Inc. |
Pd−1に結合する抗原結合蛋白質
|
ES2865473T3
(es)
|
2013-07-10 |
2021-10-15 |
Sutro Biopharma Inc |
Anticuerpos que comprenden múltiples residuos de aminoácidos no naturales sitio-específicos, métodos para su preparación y métodos de uso
|
WO2015054658A1
(en)
|
2013-10-11 |
2015-04-16 |
Sutro Biopharma, Inc. |
Modified amino acids comprising tetrazine functional groups, methods of preparation, and methods of their use
|
US9388239B2
(en)
|
2014-05-01 |
2016-07-12 |
Consejo Nacional De Investigation Cientifica |
Anti-human VEGF antibodies with unusually strong binding affinity to human VEGF-A and cross reactivity to human VEGF-B
|
US11311519B2
(en)
|
2014-05-01 |
2022-04-26 |
Eiger Biopharmaceuticals, Inc. |
Treatment of hepatitis delta virus infection
|
US10076512B2
(en)
|
2014-05-01 |
2018-09-18 |
Eiger Biopharmaceuticals, Inc. |
Treatment of hepatitis delta virus infection
|
DK3137078T3
(da)
|
2014-05-01 |
2019-06-11 |
Eiger Biopharmaceuticals Inc |
Behandling af hepatitis delta-virusinfektion
|
CA2989550C
(en)
|
2014-06-18 |
2023-08-08 |
Demerx, Inc. |
Halogenated indole and benzofuran derivatives of isoquinuclidene and processes for preparing them
|
US20170216403A1
(en)
|
2014-08-12 |
2017-08-03 |
Massachusetts Institute Of Technology |
Synergistic tumor treatment with il-2, a therapeutic antibody, and an immune checkpoint blocker
|
DK3180018T3
(da)
|
2014-08-12 |
2019-10-28 |
Massachusetts Inst Technology |
Synergistisk tumorbehandling med IL-2 og integrinbindende Fc-fusionsprotein
|
EA201790437A1
(ru)
|
2014-08-22 |
2017-08-31 |
Сорренто Терапьютикс, Инк. |
Антигенсвязывающие белки, связывающиеся с cxcr3
|
US9987241B2
(en)
|
2014-09-25 |
2018-06-05 |
The Board Of Regents Of The University Of Oklahoma |
Enzyme conjugate and prodrug cancer therapy
|
KR102637699B1
(ko)
|
2014-10-24 |
2024-02-19 |
브리스톨-마이어스 스큅 컴퍼니 |
변형된 fgf-21 폴리펩티드 및 그의 용도
|
PL3215193T3
(pl)
*
|
2014-11-06 |
2024-03-18 |
Pharmaessentia Corporation |
Reżim podawania pegylowanego interferonu
|
US20180066229A1
(en)
*
|
2015-03-17 |
2018-03-08 |
Shinshu University |
Method for preparing dendritic cells via non-adhesive culture using ifn
|
KR102514971B1
(ko)
|
2015-04-21 |
2023-03-27 |
아이거 바이오파마슈티컬스 인코포레이티드 |
로나파르닙 및 리토나버를 포함하는 약제 조성물
|
JP6668468B2
(ja)
|
2015-11-03 |
2020-03-18 |
エフ.ホフマン−ラ ロシュ アーゲーF. Hoffmann−La Roche Aktiengesellschaft |
Hbvキャプシドアセンブリ阻害剤とインターフェロンの併用療法
|
DK3370723T3
(da)
|
2015-11-04 |
2021-01-25 |
Eiger Biopharmaceuticals Inc |
Behandling af hepatitis delta-virusinfektion
|
CN109715821B
(zh)
|
2016-01-29 |
2022-09-06 |
索伦托药业有限公司 |
与pd-l1结合的抗原结合蛋白
|
WO2018087345A1
(en)
|
2016-11-14 |
2018-05-17 |
F. Hoffmann-La Roche Ag |
COMBINATION THERAPY OF AN HBsAg INHIBITOR, A NUCLEOS(T)IDE ANALOGUE AND AN INTERFERON
|
AU2018207303A1
(en)
|
2017-01-10 |
2019-07-25 |
xCella Biosciences, Inc. |
Combination tumor treatment with an integrin-binding-Fc fusion protein and immune modulator
|
US10350266B2
(en)
|
2017-01-10 |
2019-07-16 |
Nodus Therapeutics, Inc. |
Method of treating cancer with a multiple integrin binding Fc fusion protein
|
US20190374611A1
(en)
|
2017-01-18 |
2019-12-12 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Methods and pharmaceutical compositions for the treatment patients suffering from myeloproliferative disorders
|
SG11201907209QA
(en)
|
2017-02-08 |
2019-09-27 |
Bristol Myers Squibb Co |
Modified relaxin polypeptides comprising a pharmacokinetic enhancer and uses thereof
|
EP3658173A1
(en)
|
2017-07-25 |
2020-06-03 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Methods and pharmaceutical compositions for modulating monocytopoiesis
|
WO2020032951A1
(en)
|
2018-08-09 |
2020-02-13 |
The Board Of Regents Of The University Of Oklahoma |
Antimalarial enzyme conjugates, kits containing same, and methods of producing and using same
|
US11485781B2
(en)
|
2017-08-17 |
2022-11-01 |
Massachusetts Institute Of Technology |
Multiple specificity binders of CXC chemokines
|
PL3849614T3
(pl)
|
2018-09-11 |
2024-04-22 |
Ambrx, Inc. |
Koniugaty polipeptydu interleukiny-2 i ich zastosowania
|
KR20210068478A
(ko)
|
2018-09-28 |
2021-06-09 |
메사추세츠 인스티튜트 오브 테크놀로지 |
콜라겐-국재화된 면역조정성 분자 및 그의 방법
|
CN113366015A
(zh)
|
2018-10-19 |
2021-09-07 |
Ambrx公司 |
白细胞介素-10多肽缀合物、其二聚体及其用途
|
WO2020154032A1
(en)
|
2019-01-23 |
2020-07-30 |
Massachusetts Institute Of Technology |
Combination immunotherapy dosing regimen for immune checkpoint blockade
|
EP3923991A1
(en)
|
2019-02-12 |
2021-12-22 |
Ambrx, Inc. |
Compositions containing, methods and uses of antibody-tlr agonist conjugates
|
AU2020312735A1
(en)
|
2019-07-18 |
2021-12-16 |
Enyo Pharma |
Method for decreasing adverse-effects of interferon
|
TW202146011A
(zh)
|
2020-03-05 |
2021-12-16 |
美商詹森藥物公司 |
治療b型肝炎病毒感染之組合療法
|
AU2021233909A1
(en)
|
2020-03-11 |
2022-09-29 |
Ambrx, Inc. |
Interleukin-2 polypeptide conjugates and methods of use thereof
|
WO2021228983A1
(en)
|
2020-05-13 |
2021-11-18 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
A pharmaceutical composition comprising an arsenic compound, an inductor of type-1 ifn and a protein kinase inhibitor for treating cancer
|
EP3912627B1
(en)
|
2020-05-20 |
2022-09-07 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Methods for the treatment of coronavirus infections
|
JP2023531682A
(ja)
|
2020-06-22 |
2023-07-25 |
ヤンセン ファーマシューティカルズ,インコーポレーテッド |
D型肝炎ウイルス感染の処置のための組成物および方法
|
KR20230073200A
(ko)
|
2020-08-20 |
2023-05-25 |
암브룩스, 인코포레이티드 |
항체-tlr 작용제 접합체, 그 방법 및 용도
|
WO2022043496A2
(en)
|
2020-08-28 |
2022-03-03 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Use of mait cells as biomarkers and biotargets in covid-19
|
WO2022079205A1
(en)
|
2020-10-15 |
2022-04-21 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Use of ifn-alpha polypeptides for the treatment of coronavirus infections
|
WO2022159414A1
(en)
|
2021-01-22 |
2022-07-28 |
University Of Rochester |
Erythropoietin for gastroinfestinal dysfunction
|
JP2024512775A
(ja)
|
2021-04-03 |
2024-03-19 |
アンブルックス,インコーポレイテッド |
抗her2抗体薬物コンジュゲート及びその使用
|