DE69737070T2 - Systeme zur präsentation von mhc-antigenen der klasse ii und verfahren zur aktivierung von cd4?+-t-lymphozyten - Google Patents
Systeme zur präsentation von mhc-antigenen der klasse ii und verfahren zur aktivierung von cd4?+-t-lymphozyten Download PDFInfo
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- DE69737070T2 DE69737070T2 DE69737070T DE69737070T DE69737070T2 DE 69737070 T2 DE69737070 T2 DE 69737070T2 DE 69737070 T DE69737070 T DE 69737070T DE 69737070 T DE69737070 T DE 69737070T DE 69737070 T2 DE69737070 T2 DE 69737070T2
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Landscapes
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Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US1817596P | 1996-05-23 | 1996-05-23 | |
| US18175P | 1996-05-23 | ||
| PCT/US1997/008697 WO1997046256A1 (en) | 1996-05-23 | 1997-05-22 | Mhc class ii antigen-presenting systems and methods for activating cd4+ t cells |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| DE69737070D1 DE69737070D1 (de) | 2007-01-18 |
| DE69737070T2 true DE69737070T2 (de) | 2007-06-21 |
Family
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Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DE69737070T Expired - Lifetime DE69737070T2 (de) | 1996-05-23 | 1997-05-22 | Systeme zur präsentation von mhc-antigenen der klasse ii und verfahren zur aktivierung von cd4?+-t-lymphozyten |
Country Status (12)
| Country | Link |
|---|---|
| US (4) | US6355479B1 (enExample) |
| EP (1) | EP0969865B1 (enExample) |
| JP (2) | JP5006998B2 (enExample) |
| AT (1) | ATE347588T1 (enExample) |
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| DE (1) | DE69737070T2 (enExample) |
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| ES (1) | ES2278390T3 (enExample) |
| IL (1) | IL126843A (enExample) |
| PT (1) | PT969865E (enExample) |
| WO (1) | WO1997046256A1 (enExample) |
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| ES2278390T3 (es) * | 1996-05-23 | 2007-08-01 | The Scripps Research Institute | Sistema de presentacion de antigenos de clase ii de cmh y procedimientos de activacion de linfocitos t cd4+. |
| US6291430B1 (en) * | 1997-09-12 | 2001-09-18 | Ludwig Institute For Cancer Research | Mage-3 peptides presented by HLA class II molecules |
| AU765085B2 (en) | 1998-05-11 | 2003-09-11 | Miltenyi Biotec Gmbh | Method of direct selection of antigen-specific T cells |
| US6230662B1 (en) | 1998-06-22 | 2001-05-15 | Theresa Miale | Animal lift and transport apparatus and method for using the same |
| EP1104456A1 (en) * | 1998-08-10 | 2001-06-06 | Chiron Corporation | Engineered antigen-presenting cells expressing an array of antigens and uses thereof |
| US7807377B2 (en) | 1998-10-20 | 2010-10-05 | Salvatore Albani | Method of isolating antigen-specific T cells employing artificial antigen presenting cells |
| ATE459339T1 (de) * | 1998-10-20 | 2010-03-15 | Androclus Technologies S R L I | Künstliche antigen-spezifischen zellen und zugehörige verfahren |
| US6225443B1 (en) * | 1999-05-19 | 2001-05-01 | Wisconsin Alumni Research Foundation | Cytotoxic T lymphocyte epitopes of the major outer membrane protein of chlamydia trachomatis |
| US7521202B2 (en) | 1999-12-17 | 2009-04-21 | The Board Of Regents Of The University Of Oklahoma | Method and apparatus for the production of soluble MHC antigens and uses thereof |
| DE10009341A1 (de) * | 2000-02-22 | 2001-09-06 | Florian Kern | Verfahren zur antigen-spezifischen Stimulation von T-Lymphozyten |
| US7541184B2 (en) | 2000-02-24 | 2009-06-02 | Invitrogen Corporation | Activation and expansion of cells |
| US7572631B2 (en) | 2000-02-24 | 2009-08-11 | Invitrogen Corporation | Activation and expansion of T cells |
| WO2001080833A1 (en) * | 2000-04-20 | 2001-11-01 | Salvatore Albani | Methods for isolation, quantification, characterization and modulation of antigen-specific t cells |
| CA2433194C (en) | 2000-10-10 | 2012-04-03 | The Board Of Regents Of The University Of Oklahoma | Comparative ligand mapping from mhc positive cells |
| US20070026433A1 (en) | 2001-03-09 | 2007-02-01 | Hildebrand William H | Epitope testing using soluble HLA |
| WO2002056908A2 (en) * | 2001-01-16 | 2002-07-25 | Hildebrand William H | Artificial antigen-presenting cells |
| WO2002079396A2 (en) * | 2001-02-13 | 2002-10-10 | Mosca Joseph D | Biological carriers for induction of immune responses |
| US20040071671A1 (en) * | 2001-02-20 | 2004-04-15 | Leturcq Didier J. | Cell therapy method for the treatment of tumors |
| HUP0402656A3 (en) * | 2001-02-20 | 2012-03-28 | Ortho Mcneil Pharm Inc | A cell therapy method for the treatment of tumors |
| FR2824567B1 (fr) * | 2001-05-11 | 2003-08-08 | Inst Nat Sante Rech Med | Procede d'obtention de lymphocytes tr1 regulateurs specifiques d'antigene |
| US7745140B2 (en) * | 2002-01-03 | 2010-06-29 | The Trustees Of The University Of Pennsylvania | Activation and expansion of T-cells using an engineered multivalent signaling platform as a research tool |
| US7638325B2 (en) * | 2002-01-03 | 2009-12-29 | The Trustees Of The University Of Pennsylvania | Activation and expansion of T-cells using an engineered multivalent signaling platform |
| US7638326B2 (en) | 2002-01-03 | 2009-12-29 | The Trustees Of The University Of Pennsylvania | Activation and expansion of T-cells using an engineered multivalent signaling platform |
| EP1408106B1 (en) * | 2002-10-11 | 2007-02-14 | Sentoclone Therapeutics AB | Cancer immuno-therapy |
| US20040072262A1 (en) * | 2002-10-11 | 2004-04-15 | Montero-Julian Felix A. | Methods and systems for detecting MHC class I binding peptides |
| US7435592B2 (en) | 2003-05-13 | 2008-10-14 | Immunovative Therapies, Ltd. | Compositions for allogeneic cell therapy |
| EP1692504A4 (en) * | 2003-11-03 | 2007-06-27 | Beckman Coulter Inc | METHODS BASED ON DETECTION SOLUTIONS OF PEPTIDES FIXING AT THE MHC |
| DK2573166T3 (da) | 2004-02-26 | 2016-07-04 | Immunovative Therapies Ltd | Fremgangsmåder til fremstilling af T-celler til celleterapi |
| US7592431B2 (en) | 2004-02-26 | 2009-09-22 | Immunovative Therapies, Ltd. | Biodegradable T-cell Activation device |
| JP2007536522A (ja) * | 2004-05-07 | 2007-12-13 | ベックマン コールター インコーポレーティッド | Ｃｔｌの媒介による抗原提示細胞の溶解を検出するためのｍｈｃ架橋系 |
| WO2005118788A2 (en) | 2004-05-27 | 2005-12-15 | The Trustees Of The University Of Pennsylvania | Novel artificial antigen presenting cells and uses therefor |
| WO2006009838A2 (en) * | 2004-06-17 | 2006-01-26 | Beckman Coulter, Inc. | Mycobacterium tuberculosis epitopes and methods of use thereof |
| EP1712615A1 (en) * | 2005-04-15 | 2006-10-18 | Txcell | In vitro production of a cell population using feeder cells |
| CN104436190A (zh) | 2005-06-08 | 2015-03-25 | 达纳-法伯癌症研究院公司 | 通过抑制程序性细胞死亡1(pd-1)途经治疗持续性感染和癌症的方法及组合物 |
| WO2006138449A2 (en) * | 2005-06-16 | 2006-12-28 | The Wistar Institute | Method for identifying a mhc class ii-dependent tumor-associated t helper cell antigen |
| WO2007071388A1 (en) | 2005-12-21 | 2007-06-28 | Sentoclone Ab | Improved method for expansion of tumour-reactive t-lymphocytes for immunotherapy of patients with cancer |
| JP5205275B2 (ja) | 2005-12-21 | 2013-06-05 | セントクローネ インターナショナル エービー | 散在性ガンの治療法 |
| US8101173B2 (en) | 2005-12-21 | 2012-01-24 | Sentoclone International Ab | Method for treating urinary bladder cancer |
| WO2007071390A1 (en) | 2005-12-21 | 2007-06-28 | Sentoclone Ab | Method for treating malignant melanoma |
| MX2008011302A (es) * | 2006-03-01 | 2008-11-04 | Janssen Pharmaceutica Nv | Tratamiento de cancer que combina agente de linfodeplecion con linfocitos t citotoxicos y citocinas. |
| EP2079830B1 (en) * | 2006-10-04 | 2016-08-17 | Janssen Pharmaceutica NV | Preparation of inactivated artificial antigen presenting cells and their use in cell therapies |
| CA2673870A1 (en) * | 2006-12-27 | 2008-07-10 | Emory University | Compositions and methods for the treatment of infections and tumors |
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| US5242687A (en) | 1989-03-15 | 1993-09-07 | Tkb Associates Limited Partnership | Method of reducing cellular immune response involving T-cells using CD8-bearing antigen presenting cells |
| US5395760A (en) | 1989-09-05 | 1995-03-07 | Immunex Corporation | DNA encoding tumor necrosis factor-α and -β receptors |
| JP2683461B2 (ja) * | 1991-07-05 | 1997-11-26 | 住友電気工業株式会社 | 光ファイバケーブルの製造方法 |
| US5583031A (en) * | 1992-02-06 | 1996-12-10 | President And Fellows Of Harvard College | Empty major histocompatibility class II heterodimers |
| US5314813A (en) | 1992-02-19 | 1994-05-24 | Scripps Research Institute | Drosophila cell lines expressing genes encoding MHC class I antigens and B2-microglobulin and capable of assembling empty complexes and methods of making said cell lines |
| WO1996012009A2 (en) * | 1994-10-14 | 1996-04-25 | Tykocinski Mark L | Methods for engineering antigen-presenting cells |
| ES2278390T3 (es) * | 1996-05-23 | 2007-08-01 | The Scripps Research Institute | Sistema de presentacion de antigenos de clase ii de cmh y procedimientos de activacion de linfocitos t cd4+. |
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- 1997-05-22 EP EP97927709A patent/EP0969865B1/en not_active Expired - Lifetime
- 1997-05-22 AU AU32103/97A patent/AU723355B2/en not_active Expired
- 1997-05-22 JP JP50061698A patent/JP5006998B2/ja not_active Expired - Lifetime
- 1997-05-22 CA CA002254975A patent/CA2254975C/en not_active Expired - Lifetime
- 1997-05-22 PT PT97927709T patent/PT969865E/pt unknown
- 1997-05-22 WO PCT/US1997/008697 patent/WO1997046256A1/en not_active Ceased
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- 2004-07-29 US US10/903,213 patent/US7402430B2/en not_active Expired - Fee Related
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| JP5006998B2 (ja) | 2012-08-22 |
| IL126843A0 (en) | 1999-09-22 |
| CA2254975A1 (en) | 1997-12-11 |
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| IL126843A (en) | 2007-06-17 |
| US20050054090A1 (en) | 2005-03-10 |
| AU3210397A (en) | 1998-01-05 |
| US7439335B2 (en) | 2008-10-21 |
| ES2278390T3 (es) | 2007-08-01 |
| JP2000511898A (ja) | 2000-09-12 |
| US20050059144A1 (en) | 2005-03-17 |
| ATE347588T1 (de) | 2006-12-15 |
| EP0969865A4 (en) | 2001-07-11 |
| WO1997046256A1 (en) | 1997-12-11 |
| PT969865E (pt) | 2007-02-28 |
| EP0969865B1 (en) | 2006-12-06 |
| DK0969865T3 (da) | 2007-03-19 |
| DE69737070D1 (de) | 2007-01-18 |
| CA2254975C (en) | 2008-12-16 |
| JP2012143245A (ja) | 2012-08-02 |
| US6355479B1 (en) | 2002-03-12 |
| US7402430B2 (en) | 2008-07-22 |
| EP0969865A1 (en) | 2000-01-12 |
| US7074617B1 (en) | 2006-07-11 |
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