AU723355B2 - MHC class II antigen presenting systems and methods for activating CD4+ T cells - Google Patents
MHC class II antigen presenting systems and methods for activating CD4+ T cells Download PDFInfo
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- AU723355B2 AU723355B2 AU32103/97A AU3210397A AU723355B2 AU 723355 B2 AU723355 B2 AU 723355B2 AU 32103/97 A AU32103/97 A AU 32103/97A AU 3210397 A AU3210397 A AU 3210397A AU 723355 B2 AU723355 B2 AU 723355B2
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- C12N2510/00—Genetically modified cells
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S424/00—Drug, bio-affecting and body treating compositions
- Y10S424/81—Drug, bio-affecting and body treating compositions involving autoimmunity, allergy, immediate hypersensitivity, delayed hypersensitivity, immunosuppression, immunotolerance, or anergy
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Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US1817596P | 1996-05-23 | 1996-05-23 | |
| US60018175 | 1996-05-23 | ||
| PCT/US1997/008697 WO1997046256A1 (en) | 1996-05-23 | 1997-05-22 | Mhc class ii antigen-presenting systems and methods for activating cd4+ t cells |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| AU3210397A AU3210397A (en) | 1998-01-05 |
| AU723355B2 true AU723355B2 (en) | 2000-08-24 |
Family
ID=21786645
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AU32103/97A Expired AU723355B2 (en) | 1996-05-23 | 1997-05-22 | MHC class II antigen presenting systems and methods for activating CD4+ T cells |
Country Status (12)
| Country | Link |
|---|---|
| US (4) | US6355479B1 (enExample) |
| EP (1) | EP0969865B1 (enExample) |
| JP (2) | JP5006998B2 (enExample) |
| AT (1) | ATE347588T1 (enExample) |
| AU (1) | AU723355B2 (enExample) |
| CA (1) | CA2254975C (enExample) |
| DE (1) | DE69737070T2 (enExample) |
| DK (1) | DK0969865T3 (enExample) |
| ES (1) | ES2278390T3 (enExample) |
| IL (1) | IL126843A (enExample) |
| PT (1) | PT969865E (enExample) |
| WO (1) | WO1997046256A1 (enExample) |
Families Citing this family (77)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO1997046256A1 (en) * | 1996-05-23 | 1997-12-11 | The Scripps Research Institute | Mhc class ii antigen-presenting systems and methods for activating cd4+ t cells |
| US6291430B1 (en) * | 1997-09-12 | 2001-09-18 | Ludwig Institute For Cancer Research | Mage-3 peptides presented by HLA class II molecules |
| US6576428B1 (en) | 1998-05-11 | 2003-06-10 | Miltenyi Biotech Gmbh | Direct selection of antigen-specific T cells, compositions obtained thereby and methods of use thereof |
| US6230662B1 (en) | 1998-06-22 | 2001-05-15 | Theresa Miale | Animal lift and transport apparatus and method for using the same |
| EP1104456A1 (en) * | 1998-08-10 | 2001-06-06 | Chiron Corporation | Engineered antigen-presenting cells expressing an array of antigens and uses thereof |
| US7807377B2 (en) | 1998-10-20 | 2010-10-05 | Salvatore Albani | Method of isolating antigen-specific T cells employing artificial antigen presenting cells |
| US7022483B1 (en) | 1998-10-20 | 2006-04-04 | Salvatore Albani | Methods for identifying and isolating antigen-specific T cells |
| US6225443B1 (en) * | 1999-05-19 | 2001-05-01 | Wisconsin Alumni Research Foundation | Cytotoxic T lymphocyte epitopes of the major outer membrane protein of chlamydia trachomatis |
| US7521202B2 (en) | 1999-12-17 | 2009-04-21 | The Board Of Regents Of The University Of Oklahoma | Method and apparatus for the production of soluble MHC antigens and uses thereof |
| DE10009341A1 (de) * | 2000-02-22 | 2001-09-06 | Florian Kern | Verfahren zur antigen-spezifischen Stimulation von T-Lymphozyten |
| US7541184B2 (en) * | 2000-02-24 | 2009-06-02 | Invitrogen Corporation | Activation and expansion of cells |
| US7572631B2 (en) | 2000-02-24 | 2009-08-11 | Invitrogen Corporation | Activation and expansion of T cells |
| AU2000243137A1 (en) * | 2000-04-20 | 2001-11-07 | Salvatore Albani | Methods for isolation, quantification, characterization and modulation of antigen-specific t cells |
| WO2002030964A2 (en) | 2000-10-10 | 2002-04-18 | The Board Of Regents Of The University Of Oklahoma | Comparative ligand mapping from mhc positive cells |
| US20070026433A1 (en) | 2001-03-09 | 2007-02-01 | Hildebrand William H | Epitope testing using soluble HLA |
| WO2002056908A2 (en) * | 2001-01-16 | 2002-07-25 | Hildebrand William H | Artificial antigen-presenting cells |
| AU2002255532A1 (en) * | 2001-02-13 | 2002-10-15 | Joseph D. Mosca | Biological carriers for induction of immune responses |
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| WO2003057171A2 (en) * | 2002-01-03 | 2003-07-17 | The Trustees Of The University Of Pennsylvania | Activation and expansion of t-cells using an engineered multivalent signaling platform |
| US7638326B2 (en) | 2002-01-03 | 2009-12-29 | The Trustees Of The University Of Pennsylvania | Activation and expansion of T-cells using an engineered multivalent signaling platform |
| US7745140B2 (en) * | 2002-01-03 | 2010-06-29 | The Trustees Of The University Of Pennsylvania | Activation and expansion of T-cells using an engineered multivalent signaling platform as a research tool |
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| DE60218173T2 (de) | 2002-10-11 | 2007-11-22 | Sentoclone Ab | Immuntherapie für Krebs |
| US7435592B2 (en) | 2003-05-13 | 2008-10-14 | Immunovative Therapies, Ltd. | Compositions for allogeneic cell therapy |
| US20050095655A1 (en) * | 2003-11-03 | 2005-05-05 | Montero-Julian Felix A. | Solution-based methods for detecting MHC-binding peptides |
| US7592431B2 (en) | 2004-02-26 | 2009-09-22 | Immunovative Therapies, Ltd. | Biodegradable T-cell Activation device |
| LT2573166T (lt) | 2004-02-26 | 2016-09-26 | Immunovative Therapies, Ltd. | T ląstelių paruošimo būdas ląstelių terapijai |
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| EP2295588B1 (en) | 2004-05-27 | 2018-03-07 | The Trustees Of The University Of Pennsylvania | Novel artificial antigen presenting cells and uses thefor |
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| EP1712615A1 (en) * | 2005-04-15 | 2006-10-18 | Txcell | In vitro production of a cell population using feeder cells |
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| US20100080792A1 (en) * | 2005-06-16 | 2010-04-01 | Dorothee Herlyn | Method for Identifying a MHC Class II-Dependent Tumor-Associated T Helper Cell Antigen |
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| JP5244610B2 (ja) | 2005-12-21 | 2013-07-24 | セントクローネ インターナショナル エービー | ガン患者の免疫療法用腫瘍反応性ｔリンパ球の改良拡大法 |
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| US8101173B2 (en) | 2005-12-21 | 2012-01-24 | Sentoclone International Ab | Method for treating urinary bladder cancer |
| MX2008011302A (es) | 2006-03-01 | 2008-11-04 | Janssen Pharmaceutica Nv | Tratamiento de cancer que combina agente de linfodeplecion con linfocitos t citotoxicos y citocinas. |
| WO2008045286A2 (en) | 2006-10-04 | 2008-04-17 | Janssen Pharmaceutica N.V. | Preparation of inactivated artificial antigen presenting cells and their use in cell therapies |
| HUE030139T2 (en) * | 2006-12-27 | 2017-04-28 | Univ Emory | Compositions and methods for the treatment of infections |
| US20120034155A1 (en) * | 2010-08-03 | 2012-02-09 | Searete Llc, A Limited Liability Corporation Of The State Of Delaware | Artificial cells |
| US9598491B2 (en) * | 2008-11-28 | 2017-03-21 | Emory University | Methods for the treatment of infections and tumors |
| US8075895B2 (en) | 2009-09-22 | 2011-12-13 | Janssen Pharmaceutica N.V. | Identification of antigenic peptides from multiple myeloma cells |
| EP2404618A1 (en) | 2010-07-07 | 2012-01-11 | Stichting Katholieke Universiteit meer in het bijzonder Radboud Universiteit Nijmegen | Immunomodulatory protein constructs with a helical polymeric backbone. |
| AU2011287108B2 (en) * | 2010-08-06 | 2014-08-28 | Canine-Lab.Inc. | Immunological function enhancing agent |
| DK2704741T3 (da) | 2011-05-03 | 2017-11-27 | Immunovative Therapies Ltd | Fremgangsmåder til håndtering af biologiske lægemidler indeholdende levende celler |
| EP2704732B1 (en) | 2011-05-03 | 2020-03-04 | Immunovative Therapies, Ltd. | Induction of il-12 using immunotherapy |
| US9260696B2 (en) | 2012-04-24 | 2016-02-16 | Dan S. Kaufman | Method for developing natural killer cells from stem cells |
| KR102452767B1 (ko) | 2013-05-14 | 2022-10-12 | 더 보드 오브 리젠츠 오브 더 유니버시티 오브 텍사스 시스템 | 가공된 키메라 항원 수용체 (ｃａｒ) ｔ-세포의 인간 적용 |
| ES2899078T3 (es) | 2013-12-16 | 2022-03-10 | The Us Secretary Dept Of Health & Human Services Office Of Technology Transfer | Inmunoterapia contra el cáncer mediante el suministro de antígenos de MHC de clase II y una proteína de señal coestimuladora utilizando un replicón de partículas similares a un virus |
| EP3105335B1 (en) | 2014-02-14 | 2019-10-02 | Board Of Regents, The University Of Texas System | Chimeric antigen receptors and methods of making |
| US10857219B2 (en) | 2014-03-28 | 2020-12-08 | The Board Of Regents Of The University Of Oklahoma | Compositions comprising soluble HLA/M. tuberculosis-specific ligand complexes and methods of production and use thereof |
| CN106459924A (zh) | 2014-04-23 | 2017-02-22 | 得克萨斯州大学系统董事会 | 用于疗法中的嵌合抗原受体(car)及其制备方法 |
| AU2015249371B2 (en) | 2014-04-24 | 2020-04-30 | Board Of Regents, The University Of Texas System | Application of induced pluripotent stem cells to generate adoptive cell therapy products |
| EP3215535A2 (en) | 2014-11-05 | 2017-09-13 | Board of Regents, The University of Texas System | Gene modified immune effector cells and engineered cells for expansion of immune effector cells |
| US10570186B2 (en) | 2014-11-05 | 2020-02-25 | Board Of Regents, The University Of Texas System | Chimeric antigen receptors (CAR) to selectively target protein complexes |
| FR3031519B1 (fr) | 2015-01-14 | 2016-12-30 | Arkema France | Composition a base de terpolymere electroactif |
| AU2016232280B2 (en) * | 2015-03-16 | 2018-05-31 | Helmholtz Zentrum München-Deutsches Forschungszentrum Für Gesundheit Und Umwelt (Gmbh) | Method of detecting new immunogenic T cell epitopes and isolating new antigen-specific T cell receptors by means of an MHC cell library |
| EP3368075B1 (en) | 2015-10-27 | 2020-01-29 | Board of Regents, The University of Texas System | Chimeric antigen receptor molecules and uses thereof |
| IL321834A (en) | 2016-06-08 | 2025-08-01 | Precigen Inc | Cd33 specific chimeric antigen receptors |
| MA45784A (fr) | 2016-07-29 | 2019-06-05 | Juno Therapeutics Inc | Anticorps anti-idiotypes dirigés contre anti-cd19 anticorps |
| EP3538112A4 (en) | 2016-11-09 | 2020-09-02 | Musc Foundation for Research Development | CD38-NAD + REGULATED METABOLIC AXIS IN ANTITUMOR IMMUNOTHERAPY |
| AU2018207281B2 (en) | 2017-01-10 | 2024-08-01 | Precigen, Inc. | Modulating expression of polypeptides via new gene switch expression systems |
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| EP4083063A3 (en) | 2017-04-18 | 2023-01-04 | FUJIFILM Cellular Dynamics, Inc. | Antigen-specific immune effector cells |
| CA3065930A1 (en) | 2017-06-07 | 2018-12-13 | Intrexon Corporation | Expression of novel cell tags |
| CA3081336A1 (en) | 2017-10-12 | 2019-04-18 | Gregory LIZEE | T cell receptors for immunotherapy |
| US12473336B2 (en) | 2018-02-21 | 2025-11-18 | Board Of Regents, The University Of Texas System | Methods for activation and expansion of natural killer cells and uses thereof |
| WO2020113029A2 (en) | 2018-11-28 | 2020-06-04 | Board Of Regents, The University Of Texas System | Multiplex genome editing of immune cells to enhance functionality and resistance to suppressive environment |
| CN113316455A (zh) | 2018-11-29 | 2021-08-27 | 得克萨斯大学体系董事会 | 用于离体扩增自然杀伤细胞的方法及其用途 |
| JP2023500671A (ja) | 2019-11-06 | 2023-01-10 | ベイラー カレッジ オブ メディスン | がんのｔ細胞治療のための細胞傷害性エフェクターメモリーｔ細胞の産生方法 |
| US20230079539A1 (en) | 2020-02-10 | 2023-03-16 | Board Of Regents, The University Of Texas System | Methods for rapid cloning and expression of hla class i cells |
| IL298558A (en) | 2020-05-27 | 2023-01-01 | Antion Biosciences Sa | Adapter molecules redirect CAR T cells to the antigen of interest |
| US12275766B2 (en) | 2020-12-23 | 2025-04-15 | Janssen Biotech, Inc. | Neoantigen peptide mimics |
| WO2023211972A1 (en) | 2022-04-28 | 2023-11-02 | Medical University Of South Carolina | Chimeric antigen receptor modified regulatory t cells for treating cancer |
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| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5242687A (en) * | 1989-03-15 | 1993-09-07 | Tkb Associates Limited Partnership | Method of reducing cellular immune response involving T-cells using CD8-bearing antigen presenting cells |
| US5395760A (en) | 1989-09-05 | 1995-03-07 | Immunex Corporation | DNA encoding tumor necrosis factor-α and -β receptors |
| JP2683461B2 (ja) * | 1991-07-05 | 1997-11-26 | 住友電気工業株式会社 | 光ファイバケーブルの製造方法 |
| US5583031A (en) * | 1992-02-06 | 1996-12-10 | President And Fellows Of Harvard College | Empty major histocompatibility class II heterodimers |
| US5314813A (en) | 1992-02-19 | 1994-05-24 | Scripps Research Institute | Drosophila cell lines expressing genes encoding MHC class I antigens and B2-microglobulin and capable of assembling empty complexes and methods of making said cell lines |
| WO1996012009A2 (en) * | 1994-10-14 | 1996-04-25 | Tykocinski Mark L | Methods for engineering antigen-presenting cells |
| WO1997046256A1 (en) * | 1996-05-23 | 1997-12-11 | The Scripps Research Institute | Mhc class ii antigen-presenting systems and methods for activating cd4+ t cells |
-
1997
- 1997-05-22 WO PCT/US1997/008697 patent/WO1997046256A1/en not_active Ceased
- 1997-05-22 DE DE69737070T patent/DE69737070T2/de not_active Expired - Lifetime
- 1997-05-22 US US09/194,285 patent/US6355479B1/en not_active Expired - Lifetime
- 1997-05-22 JP JP50061698A patent/JP5006998B2/ja not_active Expired - Lifetime
- 1997-05-22 ES ES97927709T patent/ES2278390T3/es not_active Expired - Lifetime
- 1997-05-22 CA CA002254975A patent/CA2254975C/en not_active Expired - Lifetime
- 1997-05-22 PT PT97927709T patent/PT969865E/pt unknown
- 1997-05-22 DK DK97927709T patent/DK0969865T3/da active
- 1997-05-22 AT AT97927709T patent/ATE347588T1/de active
- 1997-05-22 EP EP97927709A patent/EP0969865B1/en not_active Expired - Lifetime
- 1997-05-22 IL IL126843A patent/IL126843A/en not_active IP Right Cessation
- 1997-05-22 AU AU32103/97A patent/AU723355B2/en not_active Expired
-
2000
- 2000-11-17 US US09/715,891 patent/US7074617B1/en not_active Expired - Fee Related
-
2004
- 2004-04-08 US US10/822,173 patent/US7439335B2/en not_active Expired - Fee Related
- 2004-07-29 US US10/903,213 patent/US7402430B2/en not_active Expired - Fee Related
-
2012
- 2012-03-29 JP JP2012077703A patent/JP2012143245A/ja not_active Withdrawn
Also Published As
| Publication number | Publication date |
|---|---|
| DE69737070T2 (de) | 2007-06-21 |
| US6355479B1 (en) | 2002-03-12 |
| EP0969865B1 (en) | 2006-12-06 |
| ATE347588T1 (de) | 2006-12-15 |
| IL126843A (en) | 2007-06-17 |
| US20050059144A1 (en) | 2005-03-17 |
| IL126843A0 (en) | 1999-09-22 |
| US7402430B2 (en) | 2008-07-22 |
| ES2278390T3 (es) | 2007-08-01 |
| US7074617B1 (en) | 2006-07-11 |
| CA2254975C (en) | 2008-12-16 |
| US20050054090A1 (en) | 2005-03-10 |
| PT969865E (pt) | 2007-02-28 |
| AU3210397A (en) | 1998-01-05 |
| US7439335B2 (en) | 2008-10-21 |
| EP0969865A4 (en) | 2001-07-11 |
| JP5006998B2 (ja) | 2012-08-22 |
| JP2000511898A (ja) | 2000-09-12 |
| WO1997046256A1 (en) | 1997-12-11 |
| JP2012143245A (ja) | 2012-08-02 |
| DK0969865T3 (da) | 2007-03-19 |
| CA2254975A1 (en) | 1997-12-11 |
| DE69737070D1 (de) | 2007-01-18 |
| EP0969865A1 (en) | 2000-01-12 |
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