CA2254975C - Mhc class ii antigen-presenting systems and methods for activating cd4+ t cells - Google Patents
Mhc class ii antigen-presenting systems and methods for activating cd4+ t cells Download PDFInfo
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- CA2254975C CA2254975C CA002254975A CA2254975A CA2254975C CA 2254975 C CA2254975 C CA 2254975C CA 002254975 A CA002254975 A CA 002254975A CA 2254975 A CA2254975 A CA 2254975A CA 2254975 C CA2254975 C CA 2254975C
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- A61K38/00—Medicinal preparations containing peptides
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2510/00—Genetically modified cells
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S424/00—Drug, bio-affecting and body treating compositions
- Y10S424/81—Drug, bio-affecting and body treating compositions involving autoimmunity, allergy, immediate hypersensitivity, delayed hypersensitivity, immunosuppression, immunotolerance, or anergy
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Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US1817596P | 1996-05-23 | 1996-05-23 | |
| US60/018,175 | 1996-05-23 | ||
| PCT/US1997/008697 WO1997046256A1 (en) | 1996-05-23 | 1997-05-22 | Mhc class ii antigen-presenting systems and methods for activating cd4+ t cells |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CA2254975A1 CA2254975A1 (en) | 1997-12-11 |
| CA2254975C true CA2254975C (en) | 2008-12-16 |
Family
ID=21786645
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA002254975A Expired - Lifetime CA2254975C (en) | 1996-05-23 | 1997-05-22 | Mhc class ii antigen-presenting systems and methods for activating cd4+ t cells |
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| Country | Link |
|---|---|
| US (4) | US6355479B1 (enExample) |
| EP (1) | EP0969865B1 (enExample) |
| JP (2) | JP5006998B2 (enExample) |
| AT (1) | ATE347588T1 (enExample) |
| AU (1) | AU723355B2 (enExample) |
| CA (1) | CA2254975C (enExample) |
| DE (1) | DE69737070T2 (enExample) |
| DK (1) | DK0969865T3 (enExample) |
| ES (1) | ES2278390T3 (enExample) |
| IL (1) | IL126843A (enExample) |
| PT (1) | PT969865E (enExample) |
| WO (1) | WO1997046256A1 (enExample) |
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| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA2254975C (en) * | 1996-05-23 | 2008-12-16 | The Scripps Research Institute | Mhc class ii antigen-presenting systems and methods for activating cd4+ t cells |
| US6291430B1 (en) * | 1997-09-12 | 2001-09-18 | Ludwig Institute For Cancer Research | Mage-3 peptides presented by HLA class II molecules |
| DE69941150D1 (de) | 1998-05-11 | 2009-09-03 | Miltenyi Biotec Gmbh | Verfahren zur direkten auswahl von antigen-spezifischen t-zellen |
| US6230662B1 (en) | 1998-06-22 | 2001-05-15 | Theresa Miale | Animal lift and transport apparatus and method for using the same |
| EP1104456A1 (en) * | 1998-08-10 | 2001-06-06 | Chiron Corporation | Engineered antigen-presenting cells expressing an array of antigens and uses thereof |
| US7807377B2 (en) | 1998-10-20 | 2010-10-05 | Salvatore Albani | Method of isolating antigen-specific T cells employing artificial antigen presenting cells |
| JP2002527467A (ja) * | 1998-10-20 | 2002-08-27 | サルバトーレ・アルバーニ | 抗原特異的ｔ細胞の単離、定量、特徴づけおよび調節方法 |
| US6225443B1 (en) * | 1999-05-19 | 2001-05-01 | Wisconsin Alumni Research Foundation | Cytotoxic T lymphocyte epitopes of the major outer membrane protein of chlamydia trachomatis |
| US7521202B2 (en) | 1999-12-17 | 2009-04-21 | The Board Of Regents Of The University Of Oklahoma | Method and apparatus for the production of soluble MHC antigens and uses thereof |
| US7541429B2 (en) | 2000-10-10 | 2009-06-02 | The Board Of Regents Of The University Of Oklahoma | Comparative ligand mapping from MHC positive cells |
| DE10009341A1 (de) * | 2000-02-22 | 2001-09-06 | Florian Kern | Verfahren zur antigen-spezifischen Stimulation von T-Lymphozyten |
| US7572631B2 (en) | 2000-02-24 | 2009-08-11 | Invitrogen Corporation | Activation and expansion of T cells |
| US7541184B2 (en) | 2000-02-24 | 2009-06-02 | Invitrogen Corporation | Activation and expansion of cells |
| WO2001080833A1 (en) * | 2000-04-20 | 2001-11-01 | Salvatore Albani | Methods for isolation, quantification, characterization and modulation of antigen-specific t cells |
| US20070026433A1 (en) | 2001-03-09 | 2007-02-01 | Hildebrand William H | Epitope testing using soluble HLA |
| WO2002056908A2 (en) * | 2001-01-16 | 2002-07-25 | Hildebrand William H | Artificial antigen-presenting cells |
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| WO2003057171A2 (en) * | 2002-01-03 | 2003-07-17 | The Trustees Of The University Of Pennsylvania | Activation and expansion of t-cells using an engineered multivalent signaling platform |
| US7745140B2 (en) | 2002-01-03 | 2010-06-29 | The Trustees Of The University Of Pennsylvania | Activation and expansion of T-cells using an engineered multivalent signaling platform as a research tool |
| US7638326B2 (en) | 2002-01-03 | 2009-12-29 | The Trustees Of The University Of Pennsylvania | Activation and expansion of T-cells using an engineered multivalent signaling platform |
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| US20040072262A1 (en) * | 2002-10-11 | 2004-04-15 | Montero-Julian Felix A. | Methods and systems for detecting MHC class I binding peptides |
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| CN113648406A (zh) | 2013-12-16 | 2021-11-16 | 美利坚合众国, 由健康及人类服务部部长代表 | 通过使用vlp复制子投递ii类mhc抗原的癌症免疫疗法 |
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| KR20160145802A (ko) | 2014-04-23 | 2016-12-20 | 보드 오브 리전츠, 더 유니버시티 오브 텍사스 시스템 | 요법에 사용하기 위한 키메라 항원 수용체 (car) 및 이의 제조 방법 |
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| US20230079539A1 (en) | 2020-02-10 | 2023-03-16 | Board Of Regents, The University Of Texas System | Methods for rapid cloning and expression of hla class i cells |
| JP2023537558A (ja) | 2020-05-27 | 2023-09-04 | アンチオン バイオサイエンシーズ エスアー | 目的の抗原にｃａｒ ｔ細胞をリダイレクトするためのアダプター分子 |
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Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5242687A (en) | 1989-03-15 | 1993-09-07 | Tkb Associates Limited Partnership | Method of reducing cellular immune response involving T-cells using CD8-bearing antigen presenting cells |
| US5395760A (en) | 1989-09-05 | 1995-03-07 | Immunex Corporation | DNA encoding tumor necrosis factor-α and -β receptors |
| JP2683461B2 (ja) * | 1991-07-05 | 1997-11-26 | 住友電気工業株式会社 | 光ファイバケーブルの製造方法 |
| US5583031A (en) * | 1992-02-06 | 1996-12-10 | President And Fellows Of Harvard College | Empty major histocompatibility class II heterodimers |
| US5314813A (en) | 1992-02-19 | 1994-05-24 | Scripps Research Institute | Drosophila cell lines expressing genes encoding MHC class I antigens and B2-microglobulin and capable of assembling empty complexes and methods of making said cell lines |
| WO1996012009A2 (en) * | 1994-10-14 | 1996-04-25 | Tykocinski Mark L | Methods for engineering antigen-presenting cells |
| CA2254975C (en) * | 1996-05-23 | 2008-12-16 | The Scripps Research Institute | Mhc class ii antigen-presenting systems and methods for activating cd4+ t cells |
-
1997
- 1997-05-22 CA CA002254975A patent/CA2254975C/en not_active Expired - Lifetime
- 1997-05-22 ES ES97927709T patent/ES2278390T3/es not_active Expired - Lifetime
- 1997-05-22 AU AU32103/97A patent/AU723355B2/en not_active Expired
- 1997-05-22 IL IL126843A patent/IL126843A/en not_active IP Right Cessation
- 1997-05-22 JP JP50061698A patent/JP5006998B2/ja not_active Expired - Lifetime
- 1997-05-22 EP EP97927709A patent/EP0969865B1/en not_active Expired - Lifetime
- 1997-05-22 PT PT97927709T patent/PT969865E/pt unknown
- 1997-05-22 US US09/194,285 patent/US6355479B1/en not_active Expired - Lifetime
- 1997-05-22 DK DK97927709T patent/DK0969865T3/da active
- 1997-05-22 AT AT97927709T patent/ATE347588T1/de active
- 1997-05-22 WO PCT/US1997/008697 patent/WO1997046256A1/en not_active Ceased
- 1997-05-22 DE DE69737070T patent/DE69737070T2/de not_active Expired - Lifetime
-
2000
- 2000-11-17 US US09/715,891 patent/US7074617B1/en not_active Expired - Fee Related
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2004
- 2004-04-08 US US10/822,173 patent/US7439335B2/en not_active Expired - Fee Related
- 2004-07-29 US US10/903,213 patent/US7402430B2/en not_active Expired - Fee Related
-
2012
- 2012-03-29 JP JP2012077703A patent/JP2012143245A/ja not_active Withdrawn
Also Published As
| Publication number | Publication date |
|---|---|
| DK0969865T3 (da) | 2007-03-19 |
| CA2254975A1 (en) | 1997-12-11 |
| IL126843A (en) | 2007-06-17 |
| IL126843A0 (en) | 1999-09-22 |
| AU723355B2 (en) | 2000-08-24 |
| ES2278390T3 (es) | 2007-08-01 |
| EP0969865B1 (en) | 2006-12-06 |
| US20050054090A1 (en) | 2005-03-10 |
| US7402430B2 (en) | 2008-07-22 |
| US6355479B1 (en) | 2002-03-12 |
| JP2012143245A (ja) | 2012-08-02 |
| EP0969865A4 (en) | 2001-07-11 |
| EP0969865A1 (en) | 2000-01-12 |
| US7439335B2 (en) | 2008-10-21 |
| DE69737070T2 (de) | 2007-06-21 |
| DE69737070D1 (de) | 2007-01-18 |
| PT969865E (pt) | 2007-02-28 |
| AU3210397A (en) | 1998-01-05 |
| ATE347588T1 (de) | 2006-12-15 |
| JP5006998B2 (ja) | 2012-08-22 |
| US7074617B1 (en) | 2006-07-11 |
| US20050059144A1 (en) | 2005-03-17 |
| JP2000511898A (ja) | 2000-09-12 |
| WO1997046256A1 (en) | 1997-12-11 |
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