IL126843A - Mhc class ii antigen-presenting systems and methods for activating cd4+t cells in vitro - Google Patents
Mhc class ii antigen-presenting systems and methods for activating cd4+t cells in vitroInfo
- Publication number
- IL126843A IL126843A IL126843A IL12684397A IL126843A IL 126843 A IL126843 A IL 126843A IL 126843 A IL126843 A IL 126843A IL 12684397 A IL12684397 A IL 12684397A IL 126843 A IL126843 A IL 126843A
- Authority
- IL
- Israel
- Prior art keywords
- molecule
- matrix
- cells
- mhc class
- accessory
- Prior art date
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Landscapes
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Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US1817596P | 1996-05-23 | 1996-05-23 | |
| PCT/US1997/008697 WO1997046256A1 (en) | 1996-05-23 | 1997-05-22 | Mhc class ii antigen-presenting systems and methods for activating cd4+ t cells |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| IL126843A0 IL126843A0 (en) | 1999-09-22 |
| IL126843A true IL126843A (en) | 2007-06-17 |
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Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IL126843A IL126843A (en) | 1996-05-23 | 1997-05-22 | Mhc class ii antigen-presenting systems and methods for activating cd4+t cells in vitro |
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| IL (1) | IL126843A (enExample) |
| PT (1) | PT969865E (enExample) |
| WO (1) | WO1997046256A1 (enExample) |
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| US6225443B1 (en) * | 1999-05-19 | 2001-05-01 | Wisconsin Alumni Research Foundation | Cytotoxic T lymphocyte epitopes of the major outer membrane protein of chlamydia trachomatis |
| US7521202B2 (en) | 1999-12-17 | 2009-04-21 | The Board Of Regents Of The University Of Oklahoma | Method and apparatus for the production of soluble MHC antigens and uses thereof |
| DE10009341A1 (de) * | 2000-02-22 | 2001-09-06 | Florian Kern | Verfahren zur antigen-spezifischen Stimulation von T-Lymphozyten |
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| WO2005118788A2 (en) | 2004-05-27 | 2005-12-15 | The Trustees Of The University Of Pennsylvania | Novel artificial antigen presenting cells and uses therefor |
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| CN106414748B (zh) | 2014-02-14 | 2021-05-28 | 得克萨斯州大学系统董事会 | 嵌合抗原受体及制备方法 |
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| CN106459924A (zh) | 2014-04-23 | 2017-02-22 | 得克萨斯州大学系统董事会 | 用于疗法中的嵌合抗原受体(car)及其制备方法 |
| CA2945393C (en) | 2014-04-24 | 2021-03-23 | Board Of Regents, The University Of Texas System | Application of induced pluripotent stem cells to generate adoptive cell therapy products |
| US20170333480A1 (en) | 2014-11-05 | 2017-11-23 | Board Of Regents, The University Of Texas System | Gene modified immune effector cells and engineered cells for expansion of immune effector cells |
| US10570186B2 (en) | 2014-11-05 | 2020-02-25 | Board Of Regents, The University Of Texas System | Chimeric antigen receptors (CAR) to selectively target protein complexes |
| FR3031519B1 (fr) | 2015-01-14 | 2016-12-30 | Arkema France | Composition a base de terpolymere electroactif |
| KR102668219B1 (ko) * | 2015-03-16 | 2024-05-28 | 막스-델부뤽-센트럼 퓌어 몰레쿨라레 메디친 인 데어 헬름홀츠-게마인샤프트 | Mhc 세포 라이브러리를 이용하여 신규한 면역원성 t 세포 에피토프를 검출하고 신규한 항원-특이적 t 세포 수용체를 단리하는 방법 |
| EP3368075B1 (en) | 2015-10-27 | 2020-01-29 | Board of Regents, The University of Texas System | Chimeric antigen receptor molecules and uses thereof |
| JP7591342B2 (ja) | 2016-06-08 | 2024-11-28 | プレシゲン，インコーポレイテッド | Ｃｄ３３特異的キメラ抗原受容体 |
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| EP3538112B1 (en) | 2016-11-09 | 2026-02-25 | Musc Foundation for Research Development | Cd38-nad+ regulated metabolic axis in anti-tumor immunotherapy |
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| US11285196B2 (en) | 2017-03-13 | 2022-03-29 | Eslam Abbas Baseuny | Multivalent biologic constructs for inducing a therapeutic modulation of cellular response and uses thereof |
| ES2912383T3 (es) | 2017-04-18 | 2022-05-25 | Fujifilm Cellular Dynamics Inc | Células efectoras inmunitarias específicas de antígeno |
| CN110997920A (zh) | 2017-06-07 | 2020-04-10 | 英特拉克森公司 | 新型细胞标签的表达 |
| KR102823603B1 (ko) | 2017-10-12 | 2025-06-23 | 더 보드 오브 리젠츠 오브 더 유니버시티 오브 텍사스 시스템 | 면역요법을 위한 t 세포 수용체 |
| JP7273421B2 (ja) | 2018-02-21 | 2023-05-15 | ボード オブ リージェンツ，ザ ユニバーシティ オブ テキサス システム | ナチュラルキラー細胞の活性化および拡大のための方法ならびにその使用 |
| BR112021010297A2 (pt) | 2018-11-28 | 2021-08-24 | Board Of Regents, The University Of Texas System | Edição de genomas multiplexadores de células imunes para aumentar a funcionalidade e resistência ao ambiente supressivo |
| WO2020112493A1 (en) | 2018-11-29 | 2020-06-04 | Board Of Regents, The University Of Texas System | Methods for ex vivo expansion of natural killer cells and use thereof |
| CN120605327A (zh) | 2019-11-06 | 2025-09-09 | 贝勒医学院 | 用于产生细胞毒性效应子记忆t细胞以用于癌症的t细胞治疗的方法 |
| US20230079539A1 (en) | 2020-02-10 | 2023-03-16 | Board Of Regents, The University Of Texas System | Methods for rapid cloning and expression of hla class i cells |
| CN115715295A (zh) | 2020-05-27 | 2023-02-24 | 安逊生物科学股份有限公司 | 将car t细胞重新定向到感兴趣的抗原的衔接分子 |
| WO2022140759A2 (en) | 2020-12-23 | 2022-06-30 | Janssen Biotech, Inc. | Neoantigen peptide mimics |
| JP2025515324A (ja) | 2022-04-28 | 2025-05-14 | エムユーエスシー ファウンデーション フォー リサーチ ディベロップメント | がんを処置するためのキメラ抗原受容体改変調節性ｔ細胞 |
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| US5242687A (en) | 1989-03-15 | 1993-09-07 | Tkb Associates Limited Partnership | Method of reducing cellular immune response involving T-cells using CD8-bearing antigen presenting cells |
| US5395760A (en) | 1989-09-05 | 1995-03-07 | Immunex Corporation | DNA encoding tumor necrosis factor-α and -β receptors |
| JP2683461B2 (ja) * | 1991-07-05 | 1997-11-26 | 住友電気工業株式会社 | 光ファイバケーブルの製造方法 |
| US5583031A (en) * | 1992-02-06 | 1996-12-10 | President And Fellows Of Harvard College | Empty major histocompatibility class II heterodimers |
| US5314813A (en) | 1992-02-19 | 1994-05-24 | Scripps Research Institute | Drosophila cell lines expressing genes encoding MHC class I antigens and B2-microglobulin and capable of assembling empty complexes and methods of making said cell lines |
| WO1996012009A2 (en) * | 1994-10-14 | 1996-04-25 | Tykocinski Mark L | Methods for engineering antigen-presenting cells |
| ES2278390T3 (es) * | 1996-05-23 | 2007-08-01 | The Scripps Research Institute | Sistema de presentacion de antigenos de clase ii de cmh y procedimientos de activacion de linfocitos t cd4+. |
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1997
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- 1997-05-22 AT AT97927709T patent/ATE347588T1/de active
- 1997-05-22 IL IL126843A patent/IL126843A/en not_active IP Right Cessation
- 1997-05-22 EP EP97927709A patent/EP0969865B1/en not_active Expired - Lifetime
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- 1997-05-22 JP JP50061698A patent/JP5006998B2/ja not_active Expired - Lifetime
- 1997-05-22 CA CA002254975A patent/CA2254975C/en not_active Expired - Lifetime
- 1997-05-22 PT PT97927709T patent/PT969865E/pt unknown
- 1997-05-22 WO PCT/US1997/008697 patent/WO1997046256A1/en not_active Ceased
- 1997-05-22 US US09/194,285 patent/US6355479B1/en not_active Expired - Lifetime
- 1997-05-22 DE DE69737070T patent/DE69737070T2/de not_active Expired - Lifetime
- 1997-05-22 DK DK97927709T patent/DK0969865T3/da active
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Also Published As
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|---|---|
| JP5006998B2 (ja) | 2012-08-22 |
| IL126843A0 (en) | 1999-09-22 |
| CA2254975A1 (en) | 1997-12-11 |
| AU723355B2 (en) | 2000-08-24 |
| US20050054090A1 (en) | 2005-03-10 |
| AU3210397A (en) | 1998-01-05 |
| US7439335B2 (en) | 2008-10-21 |
| ES2278390T3 (es) | 2007-08-01 |
| DE69737070T2 (de) | 2007-06-21 |
| JP2000511898A (ja) | 2000-09-12 |
| US20050059144A1 (en) | 2005-03-17 |
| ATE347588T1 (de) | 2006-12-15 |
| EP0969865A4 (en) | 2001-07-11 |
| WO1997046256A1 (en) | 1997-12-11 |
| PT969865E (pt) | 2007-02-28 |
| EP0969865B1 (en) | 2006-12-06 |
| DK0969865T3 (da) | 2007-03-19 |
| DE69737070D1 (de) | 2007-01-18 |
| CA2254975C (en) | 2008-12-16 |
| JP2012143245A (ja) | 2012-08-02 |
| US6355479B1 (en) | 2002-03-12 |
| US7402430B2 (en) | 2008-07-22 |
| EP0969865A1 (en) | 2000-01-12 |
| US7074617B1 (en) | 2006-07-11 |
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