IL126843A - Mhc class ii antigen-presenting systems and methods for activating cd4+t cells in vitro - Google Patents
Mhc class ii antigen-presenting systems and methods for activating cd4+t cells in vitroInfo
- Publication number
- IL126843A IL126843A IL126843A IL12684397A IL126843A IL 126843 A IL126843 A IL 126843A IL 126843 A IL126843 A IL 126843A IL 12684397 A IL12684397 A IL 12684397A IL 126843 A IL126843 A IL 126843A
- Authority
- IL
- Israel
- Prior art keywords
- molecule
- matrix
- cells
- mhc class
- accessory
- Prior art date
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Landscapes
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Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US1817596P | 1996-05-23 | 1996-05-23 | |
| PCT/US1997/008697 WO1997046256A1 (en) | 1996-05-23 | 1997-05-22 | Mhc class ii antigen-presenting systems and methods for activating cd4+ t cells |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| IL126843A0 IL126843A0 (en) | 1999-09-22 |
| IL126843A true IL126843A (en) | 2007-06-17 |
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Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IL126843A IL126843A (en) | 1996-05-23 | 1997-05-22 | Mhc class ii antigen-presenting systems and methods for activating cd4+t cells in vitro |
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| JP (2) | JP5006998B2 (enExample) |
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| IL (1) | IL126843A (enExample) |
| PT (1) | PT969865E (enExample) |
| WO (1) | WO1997046256A1 (enExample) |
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| US7521202B2 (en) | 1999-12-17 | 2009-04-21 | The Board Of Regents Of The University Of Oklahoma | Method and apparatus for the production of soluble MHC antigens and uses thereof |
| DE10009341A1 (de) * | 2000-02-22 | 2001-09-06 | Florian Kern | Verfahren zur antigen-spezifischen Stimulation von T-Lymphozyten |
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| ES2899078T3 (es) | 2013-12-16 | 2022-03-10 | The Us Secretary Dept Of Health & Human Services Office Of Technology Transfer | Inmunoterapia contra el cáncer mediante el suministro de antígenos de MHC de clase II y una proteína de señal coestimuladora utilizando un replicón de partículas similares a un virus |
| EP3105335B1 (en) | 2014-02-14 | 2019-10-02 | Board Of Regents, The University Of Texas System | Chimeric antigen receptors and methods of making |
| US10857219B2 (en) | 2014-03-28 | 2020-12-08 | The Board Of Regents Of The University Of Oklahoma | Compositions comprising soluble HLA/M. tuberculosis-specific ligand complexes and methods of production and use thereof |
| CN106459924A (zh) | 2014-04-23 | 2017-02-22 | 得克萨斯州大学系统董事会 | 用于疗法中的嵌合抗原受体(car)及其制备方法 |
| AU2015249371B2 (en) | 2014-04-24 | 2020-04-30 | Board Of Regents, The University Of Texas System | Application of induced pluripotent stem cells to generate adoptive cell therapy products |
| EP3215535A2 (en) | 2014-11-05 | 2017-09-13 | Board of Regents, The University of Texas System | Gene modified immune effector cells and engineered cells for expansion of immune effector cells |
| US10570186B2 (en) | 2014-11-05 | 2020-02-25 | Board Of Regents, The University Of Texas System | Chimeric antigen receptors (CAR) to selectively target protein complexes |
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| EP3368075B1 (en) | 2015-10-27 | 2020-01-29 | Board of Regents, The University of Texas System | Chimeric antigen receptor molecules and uses thereof |
| IL321834A (en) | 2016-06-08 | 2025-08-01 | Precigen Inc | Cd33 specific chimeric antigen receptors |
| MA45784A (fr) | 2016-07-29 | 2019-06-05 | Juno Therapeutics Inc | Anticorps anti-idiotypes dirigés contre anti-cd19 anticorps |
| EP3538112A4 (en) | 2016-11-09 | 2020-09-02 | Musc Foundation for Research Development | CD38-NAD + REGULATED METABOLIC AXIS IN ANTITUMOR IMMUNOTHERAPY |
| AU2018207281B2 (en) | 2017-01-10 | 2024-08-01 | Precigen, Inc. | Modulating expression of polypeptides via new gene switch expression systems |
| US11285196B2 (en) | 2017-03-13 | 2022-03-29 | Eslam Abbas Baseuny | Multivalent biologic constructs for inducing a therapeutic modulation of cellular response and uses thereof |
| EP4083063A3 (en) | 2017-04-18 | 2023-01-04 | FUJIFILM Cellular Dynamics, Inc. | Antigen-specific immune effector cells |
| CA3065930A1 (en) | 2017-06-07 | 2018-12-13 | Intrexon Corporation | Expression of novel cell tags |
| CA3081336A1 (en) | 2017-10-12 | 2019-04-18 | Gregory LIZEE | T cell receptors for immunotherapy |
| US12473336B2 (en) | 2018-02-21 | 2025-11-18 | Board Of Regents, The University Of Texas System | Methods for activation and expansion of natural killer cells and uses thereof |
| WO2020113029A2 (en) | 2018-11-28 | 2020-06-04 | Board Of Regents, The University Of Texas System | Multiplex genome editing of immune cells to enhance functionality and resistance to suppressive environment |
| CN113316455A (zh) | 2018-11-29 | 2021-08-27 | 得克萨斯大学体系董事会 | 用于离体扩增自然杀伤细胞的方法及其用途 |
| JP2023500671A (ja) | 2019-11-06 | 2023-01-10 | ベイラー カレッジ オブ メディスン | がんのｔ細胞治療のための細胞傷害性エフェクターメモリーｔ細胞の産生方法 |
| US20230079539A1 (en) | 2020-02-10 | 2023-03-16 | Board Of Regents, The University Of Texas System | Methods for rapid cloning and expression of hla class i cells |
| IL298558A (en) | 2020-05-27 | 2023-01-01 | Antion Biosciences Sa | Adapter molecules redirect CAR T cells to the antigen of interest |
| US12275766B2 (en) | 2020-12-23 | 2025-04-15 | Janssen Biotech, Inc. | Neoantigen peptide mimics |
| WO2023211972A1 (en) | 2022-04-28 | 2023-11-02 | Medical University Of South Carolina | Chimeric antigen receptor modified regulatory t cells for treating cancer |
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| US5242687A (en) * | 1989-03-15 | 1993-09-07 | Tkb Associates Limited Partnership | Method of reducing cellular immune response involving T-cells using CD8-bearing antigen presenting cells |
| US5395760A (en) | 1989-09-05 | 1995-03-07 | Immunex Corporation | DNA encoding tumor necrosis factor-α and -β receptors |
| JP2683461B2 (ja) * | 1991-07-05 | 1997-11-26 | 住友電気工業株式会社 | 光ファイバケーブルの製造方法 |
| US5583031A (en) * | 1992-02-06 | 1996-12-10 | President And Fellows Of Harvard College | Empty major histocompatibility class II heterodimers |
| US5314813A (en) | 1992-02-19 | 1994-05-24 | Scripps Research Institute | Drosophila cell lines expressing genes encoding MHC class I antigens and B2-microglobulin and capable of assembling empty complexes and methods of making said cell lines |
| WO1996012009A2 (en) * | 1994-10-14 | 1996-04-25 | Tykocinski Mark L | Methods for engineering antigen-presenting cells |
| WO1997046256A1 (en) * | 1996-05-23 | 1997-12-11 | The Scripps Research Institute | Mhc class ii antigen-presenting systems and methods for activating cd4+ t cells |
-
1997
- 1997-05-22 WO PCT/US1997/008697 patent/WO1997046256A1/en not_active Ceased
- 1997-05-22 DE DE69737070T patent/DE69737070T2/de not_active Expired - Lifetime
- 1997-05-22 US US09/194,285 patent/US6355479B1/en not_active Expired - Lifetime
- 1997-05-22 JP JP50061698A patent/JP5006998B2/ja not_active Expired - Lifetime
- 1997-05-22 ES ES97927709T patent/ES2278390T3/es not_active Expired - Lifetime
- 1997-05-22 CA CA002254975A patent/CA2254975C/en not_active Expired - Lifetime
- 1997-05-22 PT PT97927709T patent/PT969865E/pt unknown
- 1997-05-22 DK DK97927709T patent/DK0969865T3/da active
- 1997-05-22 AT AT97927709T patent/ATE347588T1/de active
- 1997-05-22 EP EP97927709A patent/EP0969865B1/en not_active Expired - Lifetime
- 1997-05-22 IL IL126843A patent/IL126843A/en not_active IP Right Cessation
- 1997-05-22 AU AU32103/97A patent/AU723355B2/en not_active Expired
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Also Published As
| Publication number | Publication date |
|---|---|
| DE69737070T2 (de) | 2007-06-21 |
| US6355479B1 (en) | 2002-03-12 |
| AU723355B2 (en) | 2000-08-24 |
| EP0969865B1 (en) | 2006-12-06 |
| ATE347588T1 (de) | 2006-12-15 |
| US20050059144A1 (en) | 2005-03-17 |
| IL126843A0 (en) | 1999-09-22 |
| US7402430B2 (en) | 2008-07-22 |
| ES2278390T3 (es) | 2007-08-01 |
| US7074617B1 (en) | 2006-07-11 |
| CA2254975C (en) | 2008-12-16 |
| US20050054090A1 (en) | 2005-03-10 |
| PT969865E (pt) | 2007-02-28 |
| AU3210397A (en) | 1998-01-05 |
| US7439335B2 (en) | 2008-10-21 |
| EP0969865A4 (en) | 2001-07-11 |
| JP5006998B2 (ja) | 2012-08-22 |
| JP2000511898A (ja) | 2000-09-12 |
| WO1997046256A1 (en) | 1997-12-11 |
| JP2012143245A (ja) | 2012-08-02 |
| DK0969865T3 (da) | 2007-03-19 |
| CA2254975A1 (en) | 1997-12-11 |
| DE69737070D1 (de) | 2007-01-18 |
| EP0969865A1 (en) | 2000-01-12 |
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