DE69615399T2 - Triacetin zur erhöhung der transdermalen penetration - Google Patents
Triacetin zur erhöhung der transdermalen penetrationInfo
- Publication number
- DE69615399T2 DE69615399T2 DE69615399T DE69615399T DE69615399T2 DE 69615399 T2 DE69615399 T2 DE 69615399T2 DE 69615399 T DE69615399 T DE 69615399T DE 69615399 T DE69615399 T DE 69615399T DE 69615399 T2 DE69615399 T2 DE 69615399T2
- Authority
- DE
- Germany
- Prior art keywords
- matrix
- drug
- adhesive
- triacetin
- skin
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
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Classifications
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- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
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- A61K9/7023—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
- A61K9/703—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms characterised by shape or structure; Details concerning release liner or backing; Refillable patches; User-activated patches
- A61K9/7038—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer
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- A61K9/7053—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds obtained by reactions only involving carbon to carbon unsaturated bonds, e.g. polyvinyl, polyisobutylene, polystyrene
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Landscapes
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical & Material Sciences (AREA)
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- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Dermatology (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Epidemiology (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Pain & Pain Management (AREA)
- Neurosurgery (AREA)
- Heart & Thoracic Surgery (AREA)
- Cardiology (AREA)
- Psychiatry (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Anesthesiology (AREA)
- Ophthalmology & Optometry (AREA)
- Urology & Nephrology (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Physical Education & Sports Medicine (AREA)
- Vascular Medicine (AREA)
- Medicinal Preparation (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US08/429,757 US5601839A (en) | 1995-04-26 | 1995-04-26 | Triacetin as a penetration enhancer for transdermal delivery of a basic drug |
| PCT/US1996/004845 WO1996033678A1 (en) | 1995-04-26 | 1996-04-08 | Triacetin as a transdermal penetration enhancer |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| DE69615399D1 DE69615399D1 (de) | 2001-10-25 |
| DE69615399T2 true DE69615399T2 (de) | 2003-01-30 |
Family
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| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DE69615399T Expired - Lifetime DE69615399T2 (de) | 1995-04-26 | 1996-04-08 | Triacetin zur erhöhung der transdermalen penetration |
| DE200512000013 Pending DE122005000013I1 (de) | 1995-04-26 | 1996-04-08 | Triacetin zur Erhöhung der transdermalen Penetration. |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DE200512000013 Pending DE122005000013I1 (de) | 1995-04-26 | 1996-04-08 | Triacetin zur Erhöhung der transdermalen Penetration. |
Country Status (18)
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|---|---|---|---|---|
| US5474783A (en) * | 1988-03-04 | 1995-12-12 | Noven Pharmaceuticals, Inc. | Solubility parameter based drug delivery system and method for altering drug saturation concentration |
| US5633000A (en) * | 1994-06-23 | 1997-05-27 | Axxia Technologies | Subcutaneous implant |
| US5785991A (en) * | 1995-06-07 | 1998-07-28 | Alza Corporation | Skin permeation enhancer compositions comprising glycerol monolaurate and lauryl acetate |
| US6512010B1 (en) | 1996-07-15 | 2003-01-28 | Alza Corporation | Formulations for the administration of fluoxetine |
| ATE322272T1 (de) * | 1996-07-15 | 2006-04-15 | Alza Corp | Neue formulierungen zur transdermale verabreichung von fluoxetin |
| US6290986B1 (en) | 1996-10-24 | 2001-09-18 | Pharmaceutical Applications Associates, Llc | Method and composition for transdermal administration of pharmacologic agents |
| US6572880B2 (en) | 1996-10-24 | 2003-06-03 | Pharmaceutical Applications Associates Llc | Methods and transdermal compositions for pain relief |
| US6479074B2 (en) | 1996-10-24 | 2002-11-12 | Pharmaceutical Applications Associates Llc | Methods and transdermal compositions for pain relief |
| AU718811B2 (en) * | 1996-10-30 | 2000-04-20 | Theratech, Inc. | Fatty acid esters of glycolic acid and its salts as permeation enhancers |
| US5980898A (en) | 1996-11-14 | 1999-11-09 | The United States Of America As Represented By The U.S. Army Medical Research & Material Command | Adjuvant for transcutaneous immunization |
| US6797276B1 (en) | 1996-11-14 | 2004-09-28 | The United States Of America As Represented By The Secretary Of The Army | Use of penetration enhancers and barrier disruption agents to enhance the transcutaneous immune response |
| US20060002949A1 (en) | 1996-11-14 | 2006-01-05 | Army Govt. Of The Usa, As Rep. By Secretary Of The Office Of The Command Judge Advocate, Hq Usamrmc. | Transcutaneous immunization without heterologous adjuvant |
| US6203817B1 (en) | 1997-02-19 | 2001-03-20 | Alza Corporation | Reduction of skin reactions caused by transdermal drug delivery |
| DE19706824C1 (de) * | 1997-02-21 | 1998-03-26 | Lohmann Therapie Syst Lts | Transdermales oder topisches Plastersystem mit Polyacrylatmatrix mit verbesserten physikalischen Eigenschaften |
| US5968547A (en) | 1997-02-24 | 1999-10-19 | Euro-Celtique, S.A. | Method of providing sustained analgesia with buprenorphine |
| US6319913B1 (en) | 1997-11-10 | 2001-11-20 | Cellegy Pharmaceuticals, Inc. | Penetration enhancing and irritation reducing systems |
| TW492882B (en) * | 1997-11-28 | 2002-07-01 | Caleb Pharmaceuticals Inc | Cholinergic antagonist plaster composition |
| US6210705B1 (en) * | 1997-12-15 | 2001-04-03 | Noven Pharmaceuticals, Nc. | Compositions and methods for treatment of attention deficit disorder and attention deficit/hyperactivity disorder with methylphenidate |
| EP1459741A1 (en) * | 1997-12-15 | 2004-09-22 | Noven Pharmaceuticals, Inc. | Compositions and methods for treatment of attention deficit disorder and attention deficit/hyperactivity disorder with menthylphenidate |
| US20020102291A1 (en) * | 1997-12-15 | 2002-08-01 | Noven Pharmaceuticals, Inc. | Compositions and method for treatment of attention deficit disorder and attention deficit/hyperactivity disorder with methylphenidate |
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- 1996-04-08 CN CNB2005100719966A patent/CN100374161C/zh not_active Expired - Lifetime
- 1996-04-08 CN CNB961934565A patent/CN1143688C/zh not_active Expired - Lifetime
- 1996-04-08 WO PCT/US1996/004845 patent/WO1996033678A1/en not_active Ceased
- 1996-04-08 DE DE69615399T patent/DE69615399T2/de not_active Expired - Lifetime
- 1996-04-08 PT PT96911647T patent/PT871420E/pt unknown
- 1996-04-08 JP JP53255096A patent/JP3228341B2/ja not_active Expired - Lifetime
- 1996-04-08 CA CA002217888A patent/CA2217888C/en not_active Expired - Lifetime
- 1996-04-08 CN CNA2004100392112A patent/CN1507918A/zh active Pending
- 1996-04-08 AU AU54467/96A patent/AU696777B2/en not_active Expired
- 1996-04-08 DK DK96911647T patent/DK0871420T3/da active
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- 1996-04-26 AR AR33630496A patent/AR001721A1/es active IP Right Grant
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