ATE322272T1 - Neue formulierungen zur transdermale verabreichung von fluoxetin - Google Patents
Neue formulierungen zur transdermale verabreichung von fluoxetinInfo
- Publication number
- ATE322272T1 ATE322272T1 AT03022248T AT03022248T ATE322272T1 AT E322272 T1 ATE322272 T1 AT E322272T1 AT 03022248 T AT03022248 T AT 03022248T AT 03022248 T AT03022248 T AT 03022248T AT E322272 T1 ATE322272 T1 AT E322272T1
- Authority
- AT
- Austria
- Prior art keywords
- fluoxetine
- transdermal administration
- composition
- enhancer
- new formulations
- Prior art date
Links
- 229960002464 fluoxetine Drugs 0.000 title abstract 10
- 239000000203 mixture Substances 0.000 title abstract 6
- RTHCYVBBDHJXIQ-UHFFFAOYSA-N N-methyl-3-phenyl-3-[4-(trifluoromethyl)phenoxy]propan-1-amine Chemical compound C=1C=CC=CC=1C(CCNC)OC1=CC=C(C(F)(F)F)C=C1 RTHCYVBBDHJXIQ-UHFFFAOYSA-N 0.000 title 1
- RTHCYVBBDHJXIQ-MRXNPFEDSA-N (R)-fluoxetine Chemical compound O([C@H](CCNC)C=1C=CC=CC=1)C1=CC=C(C(F)(F)F)C=C1 RTHCYVBBDHJXIQ-MRXNPFEDSA-N 0.000 abstract 9
- 239000003623 enhancer Substances 0.000 abstract 2
- JYGXADMDTFJGBT-VWUMJDOOSA-N hydrocortisone Chemical compound O=C1CC[C@]2(C)[C@H]3[C@@H](O)C[C@](C)([C@@](CC4)(O)C(=O)CO)[C@@H]4[C@@H]3CCC2=C1 JYGXADMDTFJGBT-VWUMJDOOSA-N 0.000 abstract 2
- 239000012528 membrane Substances 0.000 abstract 2
- QTBSBXVTEAMEQO-UHFFFAOYSA-M Acetate Chemical compound CC([O-])=O QTBSBXVTEAMEQO-UHFFFAOYSA-M 0.000 abstract 1
- 206010040880 Skin irritation Diseases 0.000 abstract 1
- 239000003246 corticosteroid Substances 0.000 abstract 1
- 238000012377 drug delivery Methods 0.000 abstract 1
- 229960000890 hydrocortisone Drugs 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 239000003961 penetration enhancing agent Substances 0.000 abstract 1
- 230000036556 skin irritation Effects 0.000 abstract 1
- 231100000475 skin irritation Toxicity 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
- A61K9/7023—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
- A61K9/703—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms characterised by shape or structure; Details concerning release liner or backing; Refillable patches; User-activated patches
- A61K9/7084—Transdermal patches having a drug layer or reservoir, and one or more separate drug-free skin-adhesive layers, e.g. between drug reservoir and skin, or surrounding the drug reservoir; Liquid-filled reservoir patches
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/13—Amines
- A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
- A61K31/138—Aryloxyalkylamines, e.g. propranolol, tamoxifen, phenoxybenzamine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
- A61K31/57—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Epidemiology (AREA)
- Animal Behavior & Ethology (AREA)
- Engineering & Computer Science (AREA)
- Public Health (AREA)
- Dermatology (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US2172796P | 1996-07-15 | 1996-07-15 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE322272T1 true ATE322272T1 (de) | 2006-04-15 |
Family
ID=32848735
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT97932610T ATE277620T1 (de) | 1996-07-15 | 1997-07-15 | Neue formulierungen zur transdermale verabreichung von fluoxetinacetat und fluoxetinmaleat |
| AT03022248T ATE322272T1 (de) | 1996-07-15 | 1997-07-15 | Neue formulierungen zur transdermale verabreichung von fluoxetin |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT97932610T ATE277620T1 (de) | 1996-07-15 | 1997-07-15 | Neue formulierungen zur transdermale verabreichung von fluoxetinacetat und fluoxetinmaleat |
Country Status (7)
| Country | Link |
|---|---|
| EP (1) | EP0946184B1 (de) |
| AT (2) | ATE277620T1 (de) |
| AU (1) | AU3601897A (de) |
| CY (1) | CY2503B1 (de) |
| DE (2) | DE69730988T2 (de) |
| ES (2) | ES2227707T3 (de) |
| WO (1) | WO1998002169A2 (de) |
Families Citing this family (21)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20030013740A1 (en) * | 1998-03-27 | 2003-01-16 | Martin P. Redmon | Stable dosage forms of fluoxetine and its enantiomers |
| EP1152749B1 (de) † | 1999-02-08 | 2006-04-12 | ALZA Corporation | Stabile nicht wässerige einphasige visköse vehikeln und formulierungen die diese vehikeln verwenden |
| US7258869B1 (en) | 1999-02-08 | 2007-08-21 | Alza Corporation | Stable non-aqueous single phase viscous vehicles and formulations utilizing such vehicle |
| US7005138B2 (en) * | 2001-12-21 | 2006-02-28 | Duramed Pharmaceuticals, Inc. | Method of systematically delivering SSRIs |
| EP1553955A4 (de) * | 2002-09-24 | 2008-11-05 | Combinatorx Inc | Verfahren und reagenzien zur behandlung von erkrankungen und störungen im zusammenhang mit erhöhten spiegeln von entzündungsfördernden zytokinen |
| US7731947B2 (en) | 2003-11-17 | 2010-06-08 | Intarcia Therapeutics, Inc. | Composition and dosage form comprising an interferon particle formulation and suspending vehicle |
| US11246913B2 (en) | 2005-02-03 | 2022-02-15 | Intarcia Therapeutics, Inc. | Suspension formulation comprising an insulinotropic peptide |
| WO2006083761A2 (en) | 2005-02-03 | 2006-08-10 | Alza Corporation | Solvent/polymer solutions as suspension vehicles |
| US20080044462A1 (en) * | 2006-04-06 | 2008-02-21 | Collegium Pharmaceutical, Inc. Delaware | Stabilized transdermal bupropion preparations |
| EP2020990B1 (de) | 2006-05-30 | 2010-09-22 | Intarcia Therapeutics, Inc | Zweiteiliger flussmodulator mit einem internen kanal für ein osmotisches ausgabesystem |
| PL2359808T3 (pl) | 2006-08-09 | 2013-10-31 | Intarcia Therapeutics Inc | Osmotyczne systemy dostawcze i zespoły tłokowe |
| EP2157967B1 (de) | 2007-04-23 | 2013-01-16 | Intarcia Therapeutics, Inc | Suspensionsformulierungen insulinotroper peptide und ihre verwendung |
| EP2240155B1 (de) | 2008-02-13 | 2012-06-06 | Intarcia Therapeutics, Inc | Vorrichtungen, formulierungen und verfahren zur freisetzung mehrerer wirkstoffe |
| EP3323423B1 (de) | 2009-09-28 | 2020-06-17 | Intarcia Therapeutics, Inc | Schnelle initiierung und/oder beendigung der verabreichung substantiell stabiler arzneimittel |
| US20120208755A1 (en) | 2011-02-16 | 2012-08-16 | Intarcia Therapeutics, Inc. | Compositions, Devices and Methods of Use Thereof for the Treatment of Cancers |
| US9889085B1 (en) | 2014-09-30 | 2018-02-13 | Intarcia Therapeutics, Inc. | Therapeutic methods for the treatment of diabetes and related conditions for patients with high baseline HbA1c |
| ES2968262T3 (es) | 2015-06-03 | 2024-05-08 | I2O Therapeutics Inc | Sistemas de colocación de implantes |
| KR20240037175A (ko) | 2016-05-16 | 2024-03-21 | 인타르시아 세라퓨틱스 인코포레이티드 | 글루카곤-수용체 선택적 폴리펩티드 및 이들의 이용 방법 |
| USD860451S1 (en) | 2016-06-02 | 2019-09-17 | Intarcia Therapeutics, Inc. | Implant removal tool |
| USD840030S1 (en) | 2016-06-02 | 2019-02-05 | Intarcia Therapeutics, Inc. | Implant placement guide |
| AU2018206539A1 (en) | 2017-01-03 | 2019-07-18 | Intarcia Therapeutics, Inc. | Methods comprising continuous administration of a GLP-1 receptor agonist and co-administration of a drug |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5411738A (en) * | 1989-03-17 | 1995-05-02 | Hind Health Care, Inc. | Method for treating nerve injury pain associated with shingles (herpes-zoster and post-herpetic neuralgia) by topical application of lidocaine |
| US5589511A (en) * | 1990-08-13 | 1996-12-31 | Sepracor Inc. | Method for treating migraine headaches using optically pure S(+) fluoxetine |
| HUT69390A (en) * | 1991-05-07 | 1995-09-28 | Dynagen Inc | Controlled, sustained release delivery system for smoking cessation |
| DE4301783C1 (de) * | 1993-01-23 | 1994-02-03 | Lohmann Therapie Syst Lts | Transdermales therapeutisches System mit Galanthamin als wirksamem Bestandteil |
| AU6410494A (en) * | 1993-03-17 | 1994-10-11 | Alza Corporation | Device for the transdermal administration of alprazolam |
| US5601839A (en) * | 1995-04-26 | 1997-02-11 | Theratech, Inc. | Triacetin as a penetration enhancer for transdermal delivery of a basic drug |
| WO1997010816A1 (en) * | 1995-09-22 | 1997-03-27 | Eli Lilly And Company | METHODS OF TREATING β-AMYLOID-ASSOCIATED CONDITIONS |
-
1997
- 1997-07-15 ES ES97932610T patent/ES2227707T3/es not_active Expired - Lifetime
- 1997-07-15 WO PCT/US1997/012335 patent/WO1998002169A2/en not_active Ceased
- 1997-07-15 AU AU36018/97A patent/AU3601897A/en not_active Abandoned
- 1997-07-15 AT AT97932610T patent/ATE277620T1/de not_active IP Right Cessation
- 1997-07-15 EP EP97932610A patent/EP0946184B1/de not_active Expired - Lifetime
- 1997-07-15 DE DE69730988T patent/DE69730988T2/de not_active Expired - Fee Related
- 1997-07-15 DE DE69735656T patent/DE69735656T2/de not_active Expired - Fee Related
- 1997-07-15 ES ES03022248T patent/ES2259746T3/es not_active Expired - Lifetime
- 1997-07-15 AT AT03022248T patent/ATE322272T1/de not_active IP Right Cessation
-
2005
- 2005-03-04 CY CY0500016A patent/CY2503B1/xx unknown
Also Published As
| Publication number | Publication date |
|---|---|
| WO1998002169A3 (en) | 1998-03-12 |
| WO1998002169A2 (en) | 1998-01-22 |
| EP0946184B1 (de) | 2004-09-29 |
| DE69735656D1 (de) | 2006-05-18 |
| HK1063148A1 (en) | 2004-12-17 |
| DE69735656T2 (de) | 2006-08-24 |
| DE69730988D1 (de) | 2004-11-04 |
| ES2259746T3 (es) | 2006-10-16 |
| DE69730988T2 (de) | 2006-02-23 |
| CY2503B1 (en) | 2005-09-02 |
| ES2227707T3 (es) | 2005-04-01 |
| ATE277620T1 (de) | 2004-10-15 |
| EP0946184A2 (de) | 1999-10-06 |
| AU3601897A (en) | 1998-02-09 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |