DE69637061D1 - Neue formulierungen zur transdermalen verabreichung von pergolid - Google Patents

Neue formulierungen zur transdermalen verabreichung von pergolid

Info

Publication number
DE69637061D1
DE69637061D1 DE69637061T DE69637061T DE69637061D1 DE 69637061 D1 DE69637061 D1 DE 69637061D1 DE 69637061 T DE69637061 T DE 69637061T DE 69637061 T DE69637061 T DE 69637061T DE 69637061 D1 DE69637061 D1 DE 69637061D1
Authority
DE
Germany
Prior art keywords
pergolide
transdermal administration
composition
pergolid
new formulations
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69637061T
Other languages
English (en)
Other versions
DE69637061T2 (de
Inventor
Su Ii Yum
Melinda K Nelson
Patricia S Campbell
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Alza Corp
Original Assignee
Alza Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Alza Corp filed Critical Alza Corp
Publication of DE69637061D1 publication Critical patent/DE69637061D1/de
Application granted granted Critical
Publication of DE69637061T2 publication Critical patent/DE69637061T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • A61K9/7023—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
    • A61K9/703—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms characterised by shape or structure; Details concerning release liner or backing; Refillable patches; User-activated patches
    • A61K9/7038—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer
    • A61K9/7046—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds
    • A61K9/7053—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds obtained by reactions only involving carbon to carbon unsaturated bonds, e.g. polyvinyl, polyisobutylene, polystyrene
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47—Quinolines; Isoquinolines
    • A61K31/48—Ergoline derivatives, e.g. lysergic acid, ergotamine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0014—Skin, i.e. galenical aspects of topical compositions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • A61K9/7023—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
    • A61K9/703—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms characterised by shape or structure; Details concerning release liner or backing; Refillable patches; User-activated patches
    • A61K9/7084—Transdermal patches having a drug layer or reservoir, and one or more separate drug-free skin-adhesive layers, e.g. between drug reservoir and skin, or surrounding the drug reservoir; Liquid-filled reservoir patches
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A61P25/16—Anti-Parkinson drugs
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/14—Esters of carboxylic acids, e.g. fatty acid monoglycerides, medium-chain triglycerides, parabens or PEG fatty acid esters
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/16—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing nitrogen, e.g. nitro-, nitroso-, azo-compounds, nitriles, cyanates
    • A61K47/18—Amines; Amides; Ureas; Quaternary ammonium compounds; Amino acids; Oligopeptides having up to five amino acids

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Dermatology (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Chemical & Material Sciences (AREA)
  • Epidemiology (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Psychology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
DE69637061T 1995-06-07 1996-06-07 Zusammensetzung und Vorrichtung zur Verabreichung von Pergolid in einer therapeutisch wirksamen Rate Expired - Lifetime DE69637061T2 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US08/473,631 US6572879B1 (en) 1995-06-07 1995-06-07 Formulations for transdermal delivery of pergolide
PCT/US1996/009692 WO1996040139A1 (en) 1995-06-07 1996-06-07 Novel formulations for transdermal delivery of pergolide
US473631 1999-12-28

Publications (2)

Publication Number Publication Date
DE69637061D1 true DE69637061D1 (de) 2007-06-14
DE69637061T2 DE69637061T2 (de) 2008-01-10

Family

ID=23880356

Family Applications (2)

Application Number Title Priority Date Filing Date
DE19681435T Withdrawn DE19681435T1 (de) 1995-06-07 1996-06-07 Neue Formulierungen zur transdermalen Abgabe von Pergolid
DE69637061T Expired - Lifetime DE69637061T2 (de) 1995-06-07 1996-06-07 Zusammensetzung und Vorrichtung zur Verabreichung von Pergolid in einer therapeutisch wirksamen Rate

Family Applications Before (1)

Application Number Title Priority Date Filing Date
DE19681435T Withdrawn DE19681435T1 (de) 1995-06-07 1996-06-07 Neue Formulierungen zur transdermalen Abgabe von Pergolid

Country Status (12)

Country Link
US (3) US6572879B1 (de)
EP (2) EP0831827B1 (de)
JP (2) JPH11507361A (de)
AT (1) ATE361073T1 (de)
AU (1) AU6476496A (de)
CA (1) CA2221263A1 (de)
DE (2) DE19681435T1 (de)
DK (1) DK0831827T3 (de)
ES (1) ES2285704T3 (de)
GB (1) GB2316004B (de)
PT (1) PT831827E (de)
WO (1) WO1996040139A1 (de)

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Also Published As

Publication number Publication date
EP0831827A1 (de) 1998-04-01
EP0831827B1 (de) 2007-05-02
PT831827E (pt) 2007-07-20
JP2007238636A (ja) 2007-09-20
US6572879B1 (en) 2003-06-03
GB9724267D0 (en) 1998-01-14
GB2316004A (en) 1998-02-18
US6001390A (en) 1999-12-14
ES2285704T3 (es) 2007-11-16
MX9709872A (es) 1998-08-30
DK0831827T3 (da) 2007-09-10
WO1996040139A1 (en) 1996-12-19
AU6476496A (en) 1996-12-30
DE19681435T1 (de) 1998-07-23
US20040209909A1 (en) 2004-10-21
CA2221263A1 (en) 1996-12-19
EP1428527A1 (de) 2004-06-16
DE69637061T2 (de) 2008-01-10
JPH11507361A (ja) 1999-06-29
ATE361073T1 (de) 2007-05-15
GB2316004B (en) 1999-08-04

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