DE69123075T2 - Ueberzogene Zusammensetzung sowie Verfahren zu ihrer Herstellung - Google Patents

Ueberzogene Zusammensetzung sowie Verfahren zu ihrer Herstellung

Info

Publication number
DE69123075T2
DE69123075T2 DE69123075T DE69123075T DE69123075T2 DE 69123075 T2 DE69123075 T2 DE 69123075T2 DE 69123075 T DE69123075 T DE 69123075T DE 69123075 T DE69123075 T DE 69123075T DE 69123075 T2 DE69123075 T2 DE 69123075T2
Authority
DE
Germany
Prior art keywords
processes
preparation
well
coated composition
coated
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69123075T
Other languages
English (en)
Other versions
DE69123075D1 (de
Inventor
Norboru Nagafuzi
Takayuki Tsukada
Kazuhiro Shima
Yasushi Takagishi
Yusuke Suzuki
Yoshitaka Tomoda
Takashi Hayashi
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Shionogi and Co Ltd
Original Assignee
Shionogi and Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority to JP9666390 priority Critical
Application filed by Shionogi and Co Ltd filed Critical Shionogi and Co Ltd
Application granted granted Critical
Publication of DE69123075T2 publication Critical patent/DE69123075T2/de
Anticipated expiration legal-status Critical
Application status is Expired - Lifetime legal-status Critical

Links

Classifications

    • BPERFORMING OPERATIONS; TRANSPORTING
    • B82NANOTECHNOLOGY
    • B82YSPECIFIC USES OR APPLICATIONS OF NANOSTRUCTURES; MEASUREMENT OR ANALYSIS OF NANOSTRUCTURES; MANUFACTURE OR TREATMENT OF NANOSTRUCTURES
    • B82Y5/00Nanobiotechnology or nanomedicine, e.g. protein engineering or drug delivery
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/69Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit
    • A61K47/6949Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit inclusion complexes, e.g. clathrates, cavitates or fullerenes
    • A61K47/6951Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit inclusion complexes, e.g. clathrates, cavitates or fullerenes using cyclodextrin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/14Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605Excipients; Inactive ingredients
    • A61K9/1629Organic macromolecular compounds
    • A61K9/1641Organic macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, poloxamers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/48Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5073Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals having two or more different coatings optionally including drug-containing subcoatings
DE69123075T 1990-04-12 1991-04-12 Ueberzogene Zusammensetzung sowie Verfahren zu ihrer Herstellung Expired - Lifetime DE69123075T2 (de)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP9666390 1990-04-12

Publications (1)

Publication Number Publication Date
DE69123075T2 true DE69123075T2 (de) 1997-03-20

Family

ID=14171060

Family Applications (2)

Application Number Title Priority Date Filing Date
DE69123075A Expired - Fee Related DE69123075D1 (de) 1990-04-12 1991-04-12 Ueberzogene Zusammensetzung sowie Verfahren zu ihrer Herstellung
DE69123075T Expired - Lifetime DE69123075T2 (de) 1990-04-12 1991-04-12 Ueberzogene Zusammensetzung sowie Verfahren zu ihrer Herstellung

Family Applications Before (1)

Application Number Title Priority Date Filing Date
DE69123075A Expired - Fee Related DE69123075D1 (de) 1990-04-12 1991-04-12 Ueberzogene Zusammensetzung sowie Verfahren zu ihrer Herstellung

Country Status (8)

Country Link
EP (1) EP0452145B1 (de)
JP (1) JP3191948B2 (de)
KR (1) KR0168849B1 (de)
AT (1) AT145131T (de)
DE (2) DE69123075D1 (de)
DK (1) DK0452145T3 (de)
ES (1) ES2096624T3 (de)
GR (1) GR3021606T3 (de)

Families Citing this family (25)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7740881B1 (en) 1993-07-01 2010-06-22 Purdue Pharma Lp Method of treating humans with opioid formulations having extended controlled release
DE4217920C2 (de) * 1992-05-30 1996-05-09 Goldwell Gmbh Verfahren zur Herstellung von pulverförmigen Mitteln zum Blondieren von menschlichen Haaren
US5429825A (en) * 1992-06-26 1995-07-04 Mcneil-Ppc, Inc. Rotomelt granulation
US5891471A (en) 1993-11-23 1999-04-06 Euro-Celtique, S.A. Pharmaceutical multiparticulates
US5849240A (en) 1993-11-23 1998-12-15 Euro-Celtique, S.A. Method of preparing sustained release pharmaceutical compositions
IL109460A (en) 1993-05-10 1998-03-10 Euro Celtique Sa Controlled release formulation comprising tramadol
FR2705677B1 (fr) * 1993-05-28 1995-08-11 Roquette Freres Micro-granules obtenus par extrusion-sphéronisation contenant une cyclodextrine.
IL110014A (en) 1993-07-01 1999-11-30 Euro Celtique Sa Solid controlled-release oral dosage forms of opioid analgesics
US5879705A (en) * 1993-07-27 1999-03-09 Euro-Celtique S.A. Sustained release compositions of morphine and a method of preparing pharmaceutical compositions
US5843480A (en) 1994-03-14 1998-12-01 Euro-Celtique, S.A. Controlled release diamorphine formulation
GB9422154D0 (en) 1994-11-03 1994-12-21 Euro Celtique Sa Pharmaceutical compositions and method of producing the same
US5965161A (en) 1994-11-04 1999-10-12 Euro-Celtique, S.A. Extruded multi-particulates
US6806294B2 (en) 1998-10-15 2004-10-19 Euro-Celtique S.A. Opioid analgesic
EP1128817A1 (de) * 1998-10-27 2001-09-05 Biovail Technologies Ltd Mikropartikel enthaltend peg und/oder peg glycerylestern
AT407111B (de) 1998-12-22 2000-12-27 Gergely Dr & Co Zucker- und/oder zuckeralkoholhältiges matrixmaterial und verfahren zu seiner herstellung
DE19918325A1 (de) 1999-04-22 2000-10-26 Euro Celtique Sa Verfahren zur Herstellung von Arzneiformen mit regulierter Wirkstofffreisetzung mittels Extrusion
US10179130B2 (en) 1999-10-29 2019-01-15 Purdue Pharma L.P. Controlled release hydrocodone formulations
BR0015284B1 (pt) 1999-10-29 2014-08-05 Euro-Celtique, S/A Formulações de hidrocodona de liberação controlada
JP4658306B2 (ja) * 2000-10-18 2011-03-23 ナガセ医薬品株式会社 錠剤用医薬組成物
KR101167465B1 (ko) 2000-10-30 2012-07-27 유로-셀티크 소시에떼 아노뉨 서방성 하이드로코돈 제형
US20110104214A1 (en) 2004-04-15 2011-05-05 Purdue Pharma L.P. Once-a-day oxycodone formulations
KR20060028821A (ko) 2001-05-02 2006-04-03 유로-셀티크 소시에떼 아노뉨 1일 1회 투여용 옥시코돈 제제
JP2005506323A (ja) * 2001-09-05 2005-03-03 ベクトゥラ・リミテッド 経口送達用機能性散剤
JP2005298412A (ja) * 2004-04-13 2005-10-27 Minato Pharmaceutical Co Ltd 被覆粒子
WO2008136380A1 (ja) * 2007-04-26 2008-11-13 Eisai R & D Management Co., Ltd. 錠剤の製造方法

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS6412267B2 (de) * 1981-09-01 1989-02-28 Teikoku Hormone Mfg Co Ltd
US4797288A (en) * 1984-10-05 1989-01-10 Warner-Lambert Company Novel drug delivery system
JP2521504B2 (ja) * 1985-12-27 1996-08-07 昭和電工株式会社 酵素の造粒法
US5019302A (en) * 1986-03-12 1991-05-28 Washington University Technology Associates, Inc. Method for granulation
DE3721721C1 (de) * 1987-07-01 1988-06-09 Hoechst Ag Verfahren zur Umhuellung von Granulaten
NZ231281A (en) * 1988-11-08 1991-01-29 Takeda Chemical Industries Ltd Sustained release pharmaceutical preparations comprising the active agent dispersed in a solid matrix of a fatty acid ester of a polyglycerol

Also Published As

Publication number Publication date
EP0452145A3 (en) 1993-03-10
KR910018016A (ko) 1991-11-30
GR3021606T3 (en) 1997-02-28
KR0168849B1 (ko) 1999-01-15
EP0452145B1 (de) 1996-11-13
JP3191948B2 (ja) 2001-07-23
AT145131T (de) 1996-11-15
JPH04217913A (en) 1992-08-07
DK0452145T3 (da) 1996-12-02
EP0452145A2 (de) 1991-10-16
ES2096624T3 (es) 1997-03-16
DE69123075D1 (de) 1996-12-19

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