DE69207799T2 - Pharmazeutische Zubereitung mit verzögerter Wirkstoffreigabe und Verfahren zur Herstellung derselben - Google Patents

Pharmazeutische Zubereitung mit verzögerter Wirkstoffreigabe und Verfahren zur Herstellung derselben

Info

Publication number
DE69207799T2
DE69207799T2 DE69207799T DE69207799T DE69207799T2 DE 69207799 T2 DE69207799 T2 DE 69207799T2 DE 69207799 T DE69207799 T DE 69207799T DE 69207799 T DE69207799 T DE 69207799T DE 69207799 T2 DE69207799 T2 DE 69207799T2
Authority
DE
Germany
Prior art keywords
release pharmaceutical
heat
effective ingredient
pharmaceutical formulation
medicinal compound
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE69207799T
Other languages
English (en)
Other versions
DE69207799D1 (de
Inventor
Kazuo Noda
Masao Kobayashi
Takashi Osawa
Toru Maejima
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Tanabe Seiyaku Co Ltd
Original Assignee
Tanabe Seiyaku Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Tanabe Seiyaku Co Ltd filed Critical Tanabe Seiyaku Co Ltd
Publication of DE69207799D1 publication Critical patent/DE69207799D1/de
Application granted granted Critical
Publication of DE69207799T2 publication Critical patent/DE69207799T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5073—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals having two or more different coatings optionally including drug-containing subcoatings
    • A61K9/5078—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals having two or more different coatings optionally including drug-containing subcoatings with drug-free core
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods

Landscapes

  • Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
DE69207799T 1991-04-08 1992-03-26 Pharmazeutische Zubereitung mit verzögerter Wirkstoffreigabe und Verfahren zur Herstellung derselben Expired - Fee Related DE69207799T2 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP3075335A JP2538134B2 (ja) 1991-04-08 1991-04-08 徐放性製剤およびその製造法

Publications (2)

Publication Number Publication Date
DE69207799D1 DE69207799D1 (de) 1996-03-07
DE69207799T2 true DE69207799T2 (de) 1996-05-30

Family

ID=13573284

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69207799T Expired - Fee Related DE69207799T2 (de) 1991-04-08 1992-03-26 Pharmazeutische Zubereitung mit verzögerter Wirkstoffreigabe und Verfahren zur Herstellung derselben

Country Status (13)

Country Link
US (1) US5389380A (de)
EP (1) EP0508653B1 (de)
JP (1) JP2538134B2 (de)
KR (1) KR0156943B1 (de)
AT (1) ATE133333T1 (de)
CA (1) CA2064150A1 (de)
DE (1) DE69207799T2 (de)
DK (1) DK0508653T3 (de)
ES (1) ES2082364T3 (de)
GR (1) GR3019505T3 (de)
HK (1) HK1003327A1 (de)
IE (1) IE71680B1 (de)
TW (1) TW223592B (de)

Families Citing this family (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5968551A (en) 1991-12-24 1999-10-19 Purdue Pharma L.P. Orally administrable opioid formulations having extended duration of effect
EP1442745A1 (de) * 1993-10-07 2004-08-04 Euro-Celtique Oral anzuwendende opioidhaltige Zusammensetzungen mit verlängerter Wirkung
DE29502547U1 (de) * 1995-02-16 1995-03-30 Roehm Gmbh Thermoplastisches Überzugs- und Bindemittel für Arzneiformen
JP5042447B2 (ja) * 1995-07-21 2012-10-03 第一三共株式会社 混合製剤
WO2000009133A1 (en) 1998-08-10 2000-02-24 Asahi Kasei Kogyo Kabushiki Kaisha Sustained release oral preparations of fasudil hydrochloride
JP2000128779A (ja) * 1998-10-20 2000-05-09 Mitsui Chemicals Inc 薬物放出制御型製剤
US6635281B2 (en) * 1998-12-23 2003-10-21 Alza Corporation Gastric retaining oral liquid dosage form
DE19933289A1 (de) * 1999-07-15 2001-01-18 Basf Ag Verfahren zur Herstellung eines Granulats aus einer Schmelze
US6254888B1 (en) 2000-01-28 2001-07-03 Boehringer Ingelheim Pharmaceuticals, Inc. Method for coating pharmaceutical dosage forms
DE10029201A1 (de) * 2000-06-19 2001-12-20 Basf Ag Verfahren zur Herstellung fester oraler Darreichungsformen mit retardierender Wirkstoffreisetzung
DK1484056T3 (da) * 2002-02-21 2013-09-08 Otsuka Pharma Co Ltd Sammensætninger med langsom frigivelse og fremgangsmåde til fremstilling af disse
PL1680089T3 (pl) 2003-10-22 2014-03-31 Lidds Ab Kompozycja zawierająca biodegradowalną ceramikę hydratującą do kontrolowanego dostarczania leków
US8188067B2 (en) 2004-04-01 2012-05-29 Teva Pharmaceutical Industries Ltd. Formulations of 6-mercaptopurine
JP2007530692A (ja) * 2004-04-01 2007-11-01 テバ ファーマシューティカル インダストリーズ リミティド ６−メルカプトプリンの改良された製剤
FR2881957B1 (fr) * 2005-02-16 2008-08-08 Solvay Comprimes comprenant une substance biologiquement active et un excipient
JP5124267B2 (ja) 2005-02-25 2013-01-23 武田薬品工業株式会社 顆粒の製造方法
US9693967B2 (en) * 2005-09-07 2017-07-04 Southwest Research Institute Biodegradable microparticle pharmaceutical formulations exhibiting improved released rates
US8110226B2 (en) * 2007-07-20 2012-02-07 Mylan Pharmaceuticals Inc. Drug formulations having inert sealed cores
US8486452B2 (en) 2007-07-20 2013-07-16 Mylan Pharmaceuticals Inc. Stabilized tolterodine tartrate formulations
US20090263482A1 (en) * 2008-04-18 2009-10-22 Vered Rosenberger Treatment of inflammatory bowel disease with 6-mercaptopurine
DE102010001620A1 (de) * 2010-02-05 2011-08-11 Siemens Aktiengesellschaft, 80333 Ständer einer permanenterregten rotierenden elektrischen Maschine
US9492395B2 (en) 2010-05-11 2016-11-15 Sensient Colors Llc Film coating composition and methods of making and using the same
WO2017066619A1 (en) 2015-10-16 2017-04-20 Teva Pharmaceutical Industries Ltd. Treatment of non-alcoholic fatty liver disease or non-alcoholic steatohepatitis with delayed-release 6-mercaptopurine
KR102000073B1 (ko) 2018-12-26 2019-07-16 주식회사 우드메탈 가구용 높낮이조절 받침장치

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS57171918A (en) 1981-04-17 1982-10-22 Eisai Co Ltd Theophyllin gradually releasing composition
JPS58214333A (ja) 1982-06-04 1983-12-13 Dai Ichi Seiyaku Co Ltd 粒状物
US4443428A (en) * 1982-06-21 1984-04-17 Euroceltique, S.A. Extended action controlled release compositions
JPS604120A (ja) * 1983-06-22 1985-01-10 Shionogi & Co Ltd 作用持続型ピナシジル製剤
US4684516A (en) * 1983-08-01 1987-08-04 Alra Laboratories, Inc. Sustained release tablets and method of making same
JPH066532B2 (ja) * 1983-09-29 1994-01-26 日産化学工業株式会社 親水性コロイドにより変性したワックス性微粉末
US4853249A (en) * 1985-11-15 1989-08-01 Taisho Pharmaceutical Co., Ltd. Method of preparing sustained-release pharmaceutical/preparation
JPH0764726B2 (ja) 1985-11-15 1995-07-12 大正製薬株式会社 持効性製剤の製造方法
JPH0647531B2 (ja) 1986-02-06 1994-06-22 第一製薬株式会社 徐放性粒状物の製造法
GB8613688D0 (en) * 1986-06-05 1986-07-09 Euro Celtique Sa Pharmaceutical composition
JPS6327424A (ja) 1986-07-17 1988-02-05 Shionogi & Co Ltd 徐放性製剤およびその製造法
GB8707740D0 (en) * 1987-04-01 1987-05-07 Strathclyde Minerals Ltd Composition
JP2668880B2 (ja) * 1987-06-23 1997-10-27 日本油脂株式会社 被覆アミノ酸類の製造方法
FI101344B (fi) * 1988-03-31 1998-06-15 Tanabe Seiyaku Co Menetelmä valmistaa valmiste, josta kontrolloidusti vapautuu farmaseut tisesti aktiivista ainetta

Also Published As

Publication number Publication date
ES2082364T3 (es) 1996-03-16
EP0508653A1 (de) 1992-10-14
KR920019339A (ko) 1992-11-19
IE71680B1 (en) 1997-02-26
JP2538134B2 (ja) 1996-09-25
DE69207799D1 (de) 1996-03-07
US5389380A (en) 1995-02-14
GR3019505T3 (en) 1996-07-31
EP0508653B1 (de) 1996-01-24
KR0156943B1 (ko) 1998-11-16
HK1003327A1 (en) 1998-10-23
JPH04312524A (ja) 1992-11-04
IE920954A1 (en) 1992-10-21
DK0508653T3 (da) 1996-06-10
ATE133333T1 (de) 1996-06-10
CA2064150A1 (en) 1992-10-09
TW223592B (de) 1994-05-11

Similar Documents

Publication Publication Date Title
DE69207799D1 (de) Pharmazeutische Zubereitung mit verzögerter Wirkstoffreigabe und Verfahren zur Herstellung derselben
ATE128863T1 (de) Arzneimittelformulierungen mit verzögerter wirkstoffabgabe.
DE69509671T2 (de) Pharmazeutische zusammensetzung mit einem schmelzbaren traegermaterial und verfahren zu seiner herstellung
HUP0004050A2 (hu) Javított oldódású itrakonazol, eljárás ennek előállítására és ezt tartalmazó orális gyógyszerkészítmény
HUT56267A (en) Process for producing pharmaceutical compositions having controlled release of active ingredient
DE59104271D1 (de) Lösungsmittelfreie, oral zu verabreichende pharmazeutische zubereitung mit verzögerter wirkstofffreisetzung und verfahren zu deren herstellung.
FI101344B1 (fi) Menetelmä valmistaa valmiste, josta kontrolloidusti vapautuu farmaseuttisesti aktiivista ainetta
ATE149826T1 (de) Verfahren zur herstellung von festen pharmazeutischen retardformen
FI914354A (fi) Menetelmä säädellysti lääkeainetta vapauttavan valmisteen valmistamiseksi
HUT64013A (en) Process for producing hiv-inhibiting phenylacetamide derivatives and pharmaceutical compositions comprising such compounds as active ingredient
ATE7228T1 (de) Imidazolinderivat, dessen salze, verfahren zur herstellung und dessen pharmazeutische zusammensetzungen.
DE69310968D1 (de) Verfahren zur Herstellung von pulverförmigem kristallinem Maltitol
ATE77052T1 (de) Verfahren zur herstellung von etofibrat oder aehnliche verbindungen enthaltende mikrogranula mit verzoegerter freisetzung sowie die auf diese weise erhaltenen produkte.
ATE110723T1 (de) Verbindungen mit magensäureinhibitorwirkung und verfahren zur herstellung.
DE3887068D1 (de) 2,2-Dimethylchromenderivate, Verfahren zur Herstellung und diese enthaltende pharmazeutische Zusammenstellungen.
DE69103922T2 (de) Verfahren zur Herstellung arzneistoffhaltiger Tabletten mit verzögerter Freigabe.
DE69614096D1 (de) Verfahren zur herstellung einer festen arzneimitteldosierungsform
ATE109137T1 (de) Pyridinderivate, verfahren zur herstellung und pharmazeutische zusammensetzungen.
DE69016592D1 (de) 4-Amidino-Chroman und 4-Amidino-Pyrano(3,2-c)pyridinderivate, Verfahren zur Herstellung und diese enthaltende pharmazeutische Zusammenstellungen.
DE69410042D1 (de) Esterverbindung, Wirkstoff zur Kontrolle von schädlichen Parasiten diese enthaltend als Wirksubstanz, Zwischenverbindung zur Herstellung der Esterverbindung, sowie Verfahren zur Herstellung der Zwischenverbindung
DE69108976D1 (de) Neue Polycarbophil enthaltende pharmazeutische Zusammensetzungen und Verfahren zu deren Herstellung.
NO179233C (no) Fremgangsmåte for fremstilling av et fast preparat for oral tilförsel omfattende en eller flere katekolforbindelser
HUT54660A (en) Process for producing new cyclic anthranilic acid-carboxylic acid derivatives and pharmaceutical compositions comprising such compounds as active ingredient
DE59500101D1 (de) Verfahren zur Herstellung von (1R,4S)-4-Hydroxy-1,2,2-trimethylcyclopentyl-methylketon sowie Derivaten und Steroisomeren dieser Verbindung
DE69313535D1 (de) N-Benzoylaminosäurederivate, diese enthaltende pharmazeutische Zusammensetzungen und Verfahren zur deren Herstellung

Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee