DE68927486D1 - Verfahren zur Integration eines bestimmten Gens ins bakterielle Chromosom und durch dieses Verfahren erhaltenes Bakterium - Google Patents
Verfahren zur Integration eines bestimmten Gens ins bakterielle Chromosom und durch dieses Verfahren erhaltenes BakteriumInfo
- Publication number
- DE68927486D1 DE68927486D1 DE68927486T DE68927486T DE68927486D1 DE 68927486 D1 DE68927486 D1 DE 68927486D1 DE 68927486 T DE68927486 T DE 68927486T DE 68927486 T DE68927486 T DE 68927486T DE 68927486 D1 DE68927486 D1 DE 68927486D1
- Authority
- DE
- Germany
- Prior art keywords
- integrating
- dna sequence
- specific gene
- bacterial chromosome
- transposon
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
- 108090000623 proteins and genes Proteins 0.000 title abstract 3
- 241000894006 Bacteria Species 0.000 title abstract 2
- 210000003578 bacterial chromosome Anatomy 0.000 title abstract 2
- 108091028043 Nucleic acid sequence Proteins 0.000 abstract 4
- 230000001580 bacterial effect Effects 0.000 abstract 1
- 210000000349 chromosome Anatomy 0.000 abstract 1
- 230000010354 integration Effects 0.000 abstract 1
Classifications
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/87—Introduction of foreign genetic material using processes not otherwise provided for, e.g. co-transformation
- C12N15/90—Stable introduction of foreign DNA into chromosome
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
- C12N15/52—Genes encoding for enzymes or proenzymes
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/67—General methods for enhancing the expression
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/70—Vectors or expression systems specially adapted for E. coli
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/74—Vectors or expression systems specially adapted for prokaryotic hosts other than E. coli, e.g. Lactobacillus, Micromonospora
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S435/00—Chemistry: molecular biology and microbiology
- Y10S435/8215—Microorganisms
- Y10S435/822—Microorganisms using bacteria or actinomycetales
- Y10S435/847—Erwinia
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S435/00—Chemistry: molecular biology and microbiology
- Y10S435/8215—Microorganisms
- Y10S435/822—Microorganisms using bacteria or actinomycetales
- Y10S435/848—Escherichia
- Y10S435/849—Escherichia coli
Landscapes
- Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Wood Science & Technology (AREA)
- Organic Chemistry (AREA)
- Biotechnology (AREA)
- General Engineering & Computer Science (AREA)
- Chemical & Material Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Zoology (AREA)
- Molecular Biology (AREA)
- Biophysics (AREA)
- Microbiology (AREA)
- Plant Pathology (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- Physics & Mathematics (AREA)
- Mycology (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Saccharide Compounds (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Immobilizing And Processing Of Enzymes And Microorganisms (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
FR8802078A FR2627508B1 (fr) | 1988-02-22 | 1988-02-22 | Procede pour l'integration d'un gene choisi sur le chromosome d'une bacterie et bacterie obtenue par ledit procede |
Publications (2)
Publication Number | Publication Date |
---|---|
DE68927486D1 true DE68927486D1 (de) | 1997-01-09 |
DE68927486T2 DE68927486T2 (de) | 1997-07-03 |
Family
ID=9363469
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE68927486T Expired - Lifetime DE68927486T2 (de) | 1988-02-22 | 1989-02-20 | Verfahren zur Integration eines bestimmten Gens ins bakterielle Chromosom und durch dieses Verfahren erhaltenes Bakterium |
Country Status (11)
Country | Link |
---|---|
US (1) | US5595889A (de) |
EP (1) | EP0332488B1 (de) |
JP (1) | JP2944094B2 (de) |
KR (1) | KR930007579B1 (de) |
AT (1) | ATE145668T1 (de) |
AU (1) | AU624353B2 (de) |
CA (1) | CA1341190C (de) |
DE (1) | DE68927486T2 (de) |
DK (1) | DK175477B1 (de) |
ES (1) | ES2097115T3 (de) |
FR (1) | FR2627508B1 (de) |
Families Citing this family (104)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP2944694B2 (ja) * | 1988-10-04 | 1999-09-06 | ディーエヌエー プラント テクノロジー コーポレイション | 検出可能な表現型のファージ形質導入による細菌の検出 |
CZ285453B6 (cs) | 1992-11-10 | 1999-08-11 | Ajinomoto Co.,Inc. | DNA, která obsahuje gen kódující aspartokinézu III, mikroorganizmus Escherichia coli a způsob výroby L-threoninu fermentací |
EP0644200B1 (de) * | 1993-01-13 | 1998-04-29 | Ajinomoto Co., Inc. | Zelloberflächenprotein aus brevibakterium lactofermentum |
JPH07155184A (ja) | 1993-12-08 | 1995-06-20 | Ajinomoto Co Inc | 発酵法によるl−リジンの製造法 |
DE69631118T2 (de) * | 1995-01-23 | 2004-07-01 | Novozymes A/S | Dna-integration durch transposition |
FR2736066B1 (fr) * | 1995-06-30 | 1998-11-20 | Ajinomoto Kk | Procede d'amplification d'un gene par transposon artificiel, bacterie coryneforme obtenue par ce procede et procede de production d'un acide amine a l'aide de cette bacterie |
WO1998040510A1 (en) * | 1997-03-11 | 1998-09-17 | Regents Of The University Of Minnesota | Dna-based transposon system for the introduction of nucleic acid into dna of a cell |
WO2000008198A1 (en) * | 1998-08-04 | 2000-02-17 | Metabolix, Inc. | Polyhydroxyalkanoate production from polyols |
AU753132B2 (en) * | 1998-08-18 | 2002-10-10 | Metabolix, Inc. | Transgenic microbial polyhydroxyalkanoate producers |
US7160682B2 (en) * | 1998-11-13 | 2007-01-09 | Regents Of The University Of Minnesota | Nucleic acid transfer vector for the introduction of nucleic acid into the DNA of a cell |
FR2791361B1 (fr) * | 1999-03-22 | 2002-12-06 | Aventis Cropscience Sa | Fragment d'acide nucleique comprenant un gene fonctionnel dans magnaporthe et un transposon impala |
EP1242457B1 (de) | 1999-12-28 | 2004-08-11 | Esbatech AG | Intrakörper mit definierter struktur ("framework"), die in einer reduzierenden umgebung stabil ist, und ihre verwendungen |
US20020094575A1 (en) * | 2000-09-14 | 2002-07-18 | Pioneer Hi-Bred International, Inc. | Compositions and methods for stable transformation using Mu bacteriophage cleaved donor complex |
EP1266966B1 (de) | 2001-06-12 | 2009-04-29 | Ajinomoto Co., Inc. | Verfahren zur Herstellung von L-Lysin oder L-Arginin unter Verwendung methanolassimilierender Bakterien |
US8227432B2 (en) * | 2002-04-22 | 2012-07-24 | Regents Of The University Of Minnesota | Transposon system and methods of use |
DE102004001674B4 (de) | 2003-01-29 | 2019-01-24 | Ajinomoto Co., Inc. | Verfahren zur Herstellung von L-Lysin unter Einsatz von Methanol verwertenden Bakterien |
FI20030561A0 (fi) * | 2003-04-14 | 2003-04-14 | Finnzymes Oy | Menetelmä nukleiinihappojen siirtämiseksi eukaryoottigenomeihin |
US20060026699A1 (en) * | 2004-06-04 | 2006-02-02 | Largaespada David A | Methods and compositions for identification of genomic sequences |
WO2006016705A1 (en) | 2004-08-10 | 2006-02-16 | Ajinomoto Co., Inc. | The use of phosphoketolase for producing useful metabolites |
KR101233739B1 (ko) | 2004-12-28 | 2013-02-18 | 아지노모토 가부시키가이샤 | L-글루탐산 생산 미생물 및 l-글루탐산의 제조방법 |
AU2006227634B2 (en) | 2005-03-16 | 2010-07-08 | Metabolix, Inc. | Chemically inducible expression of biosynthetic pathways |
JP5088136B2 (ja) | 2005-10-18 | 2012-12-05 | 味の素株式会社 | コハク酸の製造方法 |
JP2009089603A (ja) | 2006-02-02 | 2009-04-30 | Ajinomoto Co Inc | メタノール資化性細菌を用いたl−リジンの製造法 |
JP2009153382A (ja) | 2006-03-30 | 2009-07-16 | Ajinomoto Co Inc | メタノール資化性細菌を用いたカルボン酸の製造法 |
JP2009165355A (ja) | 2006-04-28 | 2009-07-30 | Ajinomoto Co Inc | L−アミノ酸を生産する微生物及びl−アミノ酸の製造法 |
EP2021458A1 (de) | 2006-05-23 | 2009-02-11 | Ajinomoto Co., Inc. | Verfahren zur herstellung einer l-aminosäure unter verwendng eines bakteriums der familie enterobacteriacea |
JP2010017082A (ja) | 2006-10-10 | 2010-01-28 | Ajinomoto Co Inc | L−アミノ酸の製造法 |
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EP3532610B1 (de) | 2016-10-27 | 2023-09-27 | Ajinomoto Co., Inc. | Verfahren zur herstellung von aldehyd |
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US10858676B2 (en) | 2017-05-22 | 2020-12-08 | Ajinomoto Co., Inc. | Method for producing objective substance |
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AU2019256065A1 (en) | 2018-04-20 | 2020-11-26 | Ajinomoto Co., Inc. | Method for secretory production of protein |
WO2020027251A1 (en) | 2018-08-03 | 2020-02-06 | Ajinomoto Co., Inc. | Method for producing objective substance |
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CN112930359A (zh) | 2018-10-25 | 2021-06-08 | 味之素株式会社 | 蛋白质的分泌生产方法 |
WO2020203885A1 (ja) | 2019-03-29 | 2020-10-08 | 味の素株式会社 | アロラクトースの製造法 |
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WO2021085405A1 (ja) | 2019-10-28 | 2021-05-06 | 味の素株式会社 | ベンズアルデヒドの製造方法 |
BR112022017430A2 (pt) | 2020-03-04 | 2022-10-18 | Ajinomoto Kk | Método e composição para produzir um alimento, transglutaminase mutante, gene, vetor, e, microrganismo |
WO2022071061A1 (ja) | 2020-09-29 | 2022-04-07 | 味の素株式会社 | 変異型トランスグルタミナーゼ |
CN116583605A (zh) | 2020-10-28 | 2023-08-11 | 味之素株式会社 | L-氨基酸的制造方法 |
CN117157394A (zh) | 2021-04-16 | 2023-12-01 | 因比奥斯公司 | 发酵生产 |
AU2022306337A1 (en) | 2021-07-07 | 2024-02-01 | Ajinomoto Co., Inc. | Method for secretory production of unnatural-amino-acid-containing protein |
Family Cites Families (10)
Publication number | Priority date | Publication date | Assignee | Title |
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JPS55156591A (en) * | 1979-05-23 | 1980-12-05 | Ajinomoto Co Inc | Method for stabilizing property of bacteria containing plasmid |
DE3380261D1 (en) * | 1982-02-17 | 1989-08-31 | Ici Plc | Vector system |
US4670388A (en) * | 1982-12-30 | 1987-06-02 | Carnegie Institution Of Washington | Method of incorporating DNA into genome of drosophila |
JPS59205983A (ja) * | 1983-04-28 | 1984-11-21 | ジエネツクス・コ−ポレイシヨン | 異種遺伝子を原核微生物で発現させる方法 |
FR2563533B1 (fr) * | 1984-04-27 | 1986-08-22 | Centre Nat Rech Scient | Procede d'amplification de l'expression d'un gene determine chez bacillus subtilis et souches obtenues |
EP0166659B1 (de) * | 1984-06-26 | 1989-08-30 | Institut National De La Recherche Agronomique (Inra) | Transformationsvektor für Hefe Yarrowia lipolytica, Transformationsverfahren und transformierte Hefe |
US4713337A (en) * | 1985-01-03 | 1987-12-15 | Massachusetts Institute Of Technology | Method for deletion of a gene from a bacteria |
FR2580233B1 (fr) * | 1985-04-12 | 1988-11-25 | Rhone Alpes Projets Plast | Procede pour rendre une matiere plastique sensible au rayon laser et permettre son marquage au laser et article obtenu notamment pour le marquage des animaux |
AU590558B2 (en) * | 1985-04-30 | 1989-11-09 | Monsanto Company | Plant-colonizing microorganisms containing the toxin gene of b. thuringiensis as a chromosomal insertion |
WO1988001646A1 (en) * | 1986-08-26 | 1988-03-10 | Allelix Inc. | Universal system for transposon mutagenesis |
-
1988
- 1988-02-22 FR FR8802078A patent/FR2627508B1/fr not_active Expired - Lifetime
-
1989
- 1989-02-20 DE DE68927486T patent/DE68927486T2/de not_active Expired - Lifetime
- 1989-02-20 EP EP89400468A patent/EP0332488B1/de not_active Expired - Lifetime
- 1989-02-20 ES ES89400468T patent/ES2097115T3/es not_active Expired - Lifetime
- 1989-02-20 AT AT89400468T patent/ATE145668T1/de not_active IP Right Cessation
- 1989-02-21 DK DK198900789A patent/DK175477B1/da not_active IP Right Cessation
- 1989-02-21 AU AU30154/89A patent/AU624353B2/en not_active Expired
- 1989-02-21 CA CA000591622A patent/CA1341190C/fr not_active Expired - Fee Related
- 1989-02-22 KR KR1019890002105A patent/KR930007579B1/ko not_active IP Right Cessation
- 1989-02-22 JP JP1042913A patent/JP2944094B2/ja not_active Expired - Lifetime
-
1994
- 1994-11-17 US US08/341,460 patent/US5595889A/en not_active Expired - Lifetime
Also Published As
Publication number | Publication date |
---|---|
US5595889A (en) | 1997-01-21 |
DE68927486T2 (de) | 1997-07-03 |
ES2097115T3 (es) | 1997-04-01 |
ATE145668T1 (de) | 1996-12-15 |
KR930007579B1 (ko) | 1993-08-13 |
AU3015489A (en) | 1989-08-24 |
DK78989A (da) | 1989-08-22 |
JP2944094B2 (ja) | 1999-08-30 |
EP0332488A1 (de) | 1989-09-13 |
DK78989D0 (da) | 1989-02-21 |
DK175477B1 (da) | 2004-11-08 |
FR2627508A1 (fr) | 1989-08-25 |
EP0332488B1 (de) | 1996-11-27 |
JPH02109985A (ja) | 1990-04-23 |
FR2627508B1 (fr) | 1990-10-05 |
AU624353B2 (en) | 1992-06-11 |
CA1341190C (fr) | 2001-02-27 |
KR890013183A (ko) | 1989-09-21 |
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