ATE145668T1 - Verfahren zur integration eines bestimmten gens ins bakterielle chromosom und durch dieses verfahren erhaltenes bakterium - Google Patents

Verfahren zur integration eines bestimmten gens ins bakterielle chromosom und durch dieses verfahren erhaltenes bakterium

Info

Publication number
ATE145668T1
ATE145668T1 AT89400468T AT89400468T ATE145668T1 AT E145668 T1 ATE145668 T1 AT E145668T1 AT 89400468 T AT89400468 T AT 89400468T AT 89400468 T AT89400468 T AT 89400468T AT E145668 T1 ATE145668 T1 AT E145668T1
Authority
AT
Austria
Prior art keywords
dna sequence
integrating
bacterial chromosome
particular gene
transposon
Prior art date
Application number
AT89400468T
Other languages
English (en)
Inventor
Francois Richaud
Bruno Jarry
Koichi Takinami
Osamu Kurahashi
Anne Beyou
Original Assignee
Eurolysine
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Eurolysine filed Critical Eurolysine
Application granted granted Critical
Publication of ATE145668T1 publication Critical patent/ATE145668T1/de

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/87Introduction of foreign genetic material using processes not otherwise provided for, e.g. co-transformation
    • C12N15/90Stable introduction of foreign DNA into chromosome
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/11DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/52Genes encoding for enzymes or proenzymes
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/63Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/67General methods for enhancing the expression
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/63Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/70Vectors or expression systems specially adapted for E. coli
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/63Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/74Vectors or expression systems specially adapted for prokaryotic hosts other than E. coli, e.g. Lactobacillus, Micromonospora
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10STECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00Chemistry: molecular biology and microbiology
    • Y10S435/8215Microorganisms
    • Y10S435/822Microorganisms using bacteria or actinomycetales
    • Y10S435/847Erwinia
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10STECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00Chemistry: molecular biology and microbiology
    • Y10S435/8215Microorganisms
    • Y10S435/822Microorganisms using bacteria or actinomycetales
    • Y10S435/848Escherichia
    • Y10S435/849Escherichia coli

Landscapes

  • Genetics & Genomics (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Wood Science & Technology (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Molecular Biology (AREA)
  • General Health & Medical Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Plant Pathology (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Saccharide Compounds (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Immobilizing And Processing Of Enzymes And Microorganisms (AREA)
AT89400468T 1988-02-22 1989-02-20 Verfahren zur integration eines bestimmten gens ins bakterielle chromosom und durch dieses verfahren erhaltenes bakterium ATE145668T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR8802078A FR2627508B1 (fr) 1988-02-22 1988-02-22 Procede pour l'integration d'un gene choisi sur le chromosome d'une bacterie et bacterie obtenue par ledit procede

Publications (1)

Publication Number Publication Date
ATE145668T1 true ATE145668T1 (de) 1996-12-15

Family

ID=9363469

Family Applications (1)

Application Number Title Priority Date Filing Date
AT89400468T ATE145668T1 (de) 1988-02-22 1989-02-20 Verfahren zur integration eines bestimmten gens ins bakterielle chromosom und durch dieses verfahren erhaltenes bakterium

Country Status (11)

Country Link
US (1) US5595889A (de)
EP (1) EP0332488B1 (de)
JP (1) JP2944094B2 (de)
KR (1) KR930007579B1 (de)
AT (1) ATE145668T1 (de)
AU (1) AU624353B2 (de)
CA (1) CA1341190C (de)
DE (1) DE68927486T2 (de)
DK (1) DK175477B1 (de)
ES (1) ES2097115T3 (de)
FR (1) FR2627508B1 (de)

Families Citing this family (109)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1990004041A1 (en) * 1988-10-04 1990-04-19 Dna Plant Technology Corporation Bacterial detection by phage transduction of detectable phenotype
ATE203769T1 (de) 1992-11-10 2001-08-15 Ajinomoto Kk Dna, die aspartokinase iii-mutanten kodiert und ihre verwendung zur herstellung von l-threonin durch fermentation
EP0644200B1 (de) * 1993-01-13 1998-04-29 Ajinomoto Co., Inc. Zelloberflächenprotein aus brevibakterium lactofermentum
JPH07155184A (ja) 1993-12-08 1995-06-20 Ajinomoto Co Inc 発酵法によるl−リジンの製造法
AU4431196A (en) * 1995-01-23 1996-08-14 Novo Nordisk A/S Dna integration by transposition
FR2736066B1 (fr) * 1995-06-30 1998-11-20 Ajinomoto Kk Procede d'amplification d'un gene par transposon artificiel, bacterie coryneforme obtenue par ce procede et procede de production d'un acide amine a l'aide de cette bacterie
DE69841648D1 (de) * 1997-03-11 2010-06-17 Univ Minnesota Dns-basiertes transposon-system für die einführung von nucleinsäure in die dns einer zelle
EP1975236B1 (de) * 1998-08-04 2015-05-06 Metabolix, Inc. Herstellung von Polyhydroxyalkanoat aus Polyolen
EP1105499B1 (de) * 1998-08-18 2006-03-08 Metabolix, Inc. Transgene polyhydroxyalkanoat produzierende mikroben
US7160682B2 (en) * 1998-11-13 2007-01-09 Regents Of The University Of Minnesota Nucleic acid transfer vector for the introduction of nucleic acid into the DNA of a cell
FR2791361B1 (fr) * 1999-03-22 2002-12-06 Aventis Cropscience Sa Fragment d'acide nucleique comprenant un gene fonctionnel dans magnaporthe et un transposon impala
EP1242457B1 (de) 1999-12-28 2004-08-11 Esbatech AG Intrakörper mit definierter struktur ("framework"), die in einer reduzierenden umgebung stabil ist, und ihre verwendungen
US20020094575A1 (en) * 2000-09-14 2002-07-18 Pioneer Hi-Bred International, Inc. Compositions and methods for stable transformation using Mu bacteriophage cleaved donor complex
DE60232120D1 (de) 2001-06-12 2009-06-10 Ajinomoto Kk Verfahren zur Herstellung von L-Lysin oder L-Arginin unter Verwendung methanolassimilierender Bakterien
WO2003089618A2 (en) * 2002-04-22 2003-10-30 Regents Of The University Of Minnesota Transposon system and methods of use
DE102004001674B4 (de) 2003-01-29 2019-01-24 Ajinomoto Co., Inc. Verfahren zur Herstellung von L-Lysin unter Einsatz von Methanol verwertenden Bakterien
FI20030561A0 (fi) * 2003-04-14 2003-04-14 Finnzymes Oy Menetelmä nukleiinihappojen siirtämiseksi eukaryoottigenomeihin
US20060026699A1 (en) * 2004-06-04 2006-02-02 Largaespada David A Methods and compositions for identification of genomic sequences
ATE463564T1 (de) 2004-08-10 2010-04-15 Ajinomoto Kk Verwendung von phosphoketolase zur herstellung geeigneter metabolite
MY170930A (en) 2004-12-28 2019-09-19 Ajinomoto Kk L-glutamic acid-producing microorganism and a method for producing l-glutamic acid
JP2008532553A (ja) * 2005-03-16 2008-08-21 メタボリックス, インコーポレイテッド 生合成経路の化学的に誘導可能な発現
WO2007046389A1 (ja) 2005-10-18 2007-04-26 Ajinomoto Co., Inc. コハク酸の製造方法
JP2009089603A (ja) 2006-02-02 2009-04-30 Ajinomoto Co Inc メタノール資化性細菌を用いたl−リジンの製造法
JP2009153382A (ja) 2006-03-30 2009-07-16 Ajinomoto Co Inc メタノール資化性細菌を用いたカルボン酸の製造法
JP2009165355A (ja) 2006-04-28 2009-07-30 Ajinomoto Co Inc L−アミノ酸を生産する微生物及びl−アミノ酸の製造法
WO2007136133A1 (en) 2006-05-23 2007-11-29 Ajinomoto Co., Inc. A method for producing an l-amino acid using a bacterium of the enterobacteriaceae family
JP2010017082A (ja) 2006-10-10 2010-01-28 Ajinomoto Co Inc L−アミノ酸の製造法
ES2631360T3 (es) 2007-01-22 2017-08-30 Ajinomoto Co., Inc. Microorganismo que produce un L-aminoácido y procedimiento para producir un L-aminoácido
JP2010088301A (ja) 2007-02-01 2010-04-22 Ajinomoto Co Inc L−アミノ酸の製造法
JP2010110217A (ja) 2007-02-22 2010-05-20 Ajinomoto Co Inc L−アミノ酸生産菌及びl−アミノ酸の製造法
JP2010130899A (ja) 2007-03-14 2010-06-17 Ajinomoto Co Inc L−グルタミン酸系アミノ酸生産微生物及びアミノ酸の製造法
WO2008126896A1 (ja) 2007-04-10 2008-10-23 Ajinomoto Co., Inc. 有機酸の製造方法
JPWO2008133131A1 (ja) 2007-04-16 2010-07-22 味の素株式会社 有機酸の製造方法
WO2008133161A1 (ja) 2007-04-17 2008-11-06 Ajinomoto Co., Inc. カルボキシル基を有する酸性物質の製造法
BRPI0816429A2 (pt) 2007-09-04 2019-09-24 Ajinomoto Kk microorganismo, e, método para a produção de um l-aminoácido.
KR20090058077A (ko) * 2007-12-04 2009-06-09 충북대학교 산학협력단 생물체 정보의 염색체 내 표지 방법 및 그 정보가 표지된생물체
WO2009072562A1 (ja) 2007-12-06 2009-06-11 Ajinomoto Co., Inc. 有機酸の製造方法
JP2011067095A (ja) 2008-01-10 2011-04-07 Ajinomoto Co Inc 発酵法による目的物質の製造法
CN102348806A (zh) 2008-01-23 2012-02-08 味之素株式会社 L-氨基酸的生产方法
EP2246420B1 (de) 2008-02-21 2014-12-31 Ajinomoto Co., Inc. L-cystein-produzierendes bakterium und verfahren zur herstellung von l-cystein
EP2264144A4 (de) 2008-02-25 2012-11-07 Ajinomoto Kk Verfahren zur herstellung von 5'-guanylsäure
JP5332237B2 (ja) 2008-03-06 2013-11-06 味の素株式会社 L−システイン生産菌及びl−システインの製造法
WO2010027022A1 (ja) 2008-09-05 2010-03-11 味の素株式会社 L-アミノ酸生産菌及びl-アミノ酸の製造法
JP2012029565A (ja) 2008-11-27 2012-02-16 Ajinomoto Co Inc L−アミノ酸の製造法
MY183971A (en) 2008-12-12 2021-03-17 Metabolix Inc Green process and compositions for producing poly(5hv) and 5 carbon chemicals
JP2010142200A (ja) 2008-12-22 2010-07-01 Ajinomoto Co Inc L−リジンの製造法
WO2010084995A2 (en) 2009-01-23 2010-07-29 Ajinomoto Co.,Inc. A method for producing an l-amino acid
JP5359409B2 (ja) 2009-03-12 2013-12-04 味の素株式会社 L−システイン生産菌及びl−システインの製造法
BRPI1014661B1 (pt) 2009-07-29 2020-12-15 Ajinomoto Co., Inc. Método para produzir um l-aminoácido
JP2012196144A (ja) 2009-08-03 2012-10-18 Ajinomoto Co Inc ビブリオ属細菌を用いたl−リジンの製造法
JP5636648B2 (ja) 2009-08-10 2014-12-10 味の素株式会社 5’−グアニル酸の製造法
JP2012223091A (ja) 2009-08-25 2012-11-15 Ajinomoto Co Inc L−アミノ酸の製造法
RU2009136544A (ru) 2009-10-05 2011-04-10 Закрытое акционерное общество "Научно-исследовательский институт "Аджиномото-Генетика" (ЗАО АГРИ) (RU) Способ получения l-цистеина с использованием бактерии семейства enterobacteriaceae
JP5817529B2 (ja) 2009-11-30 2015-11-18 味の素株式会社 L−システイン生産菌及びl−システインの製造法
RU2460793C2 (ru) 2010-01-15 2012-09-10 Закрытое акционерное общество "Научно-исследовательский институт "Аджиномото-Генетика" (ЗАО АГРИ) Способ получения l-аминокислот с использованием бактерий семейства enterobacteriaceae
CN103097530B (zh) 2010-09-08 2016-11-09 绿色苯酚开发株式会社 棒状细菌转化体及使用该转化体的苯酚的制造方法
JP5803927B2 (ja) 2010-09-14 2015-11-04 味の素株式会社 含硫アミノ酸生産菌及び含硫アミノ酸の製造法
US9404115B2 (en) 2010-11-10 2016-08-02 Green Phenol Development Co., Ltd. Coryneform bacterium transformant and process for producing phenol using the same
JP2014036576A (ja) 2010-12-10 2014-02-27 Ajinomoto Co Inc L−アミノ酸の製造法
JP2014087259A (ja) 2011-02-22 2014-05-15 Ajinomoto Co Inc L−システイン生産菌及びl−システインの製造法
PT2684867T (pt) 2011-03-09 2019-02-07 Mitsui Chemicals Inc Di-isocianato de pentametileno, método para a produção de di-isocianato de pentametileno, composição de poliisocianato, resina de poliuretano e resina de poliureia
CN104160024A (zh) 2011-04-01 2014-11-19 味之素株式会社 用于生产l-半胱氨酸的方法
DE102011006716A1 (de) 2011-04-04 2012-10-04 Evonik Degussa Gmbh Mikroorganismus und Verfahren zur fermentativen Herstellung einer organisch-chemischen Verbindung
JP2014131487A (ja) 2011-04-18 2014-07-17 Ajinomoto Co Inc L−システインの製造法
CN103946372B (zh) 2011-11-02 2016-06-08 味之素株式会社 用于分泌产生蛋白质的方法
EP2778228B1 (de) 2011-11-11 2017-05-17 Ajinomoto Co., Inc. Verfahren zur herstellung von 2-ketoglutarsäure und derivate davon unter verwendung eines bakteriums der gattung pantoea oder der gattung corynebacterium
WO2014185430A1 (ja) 2013-05-13 2014-11-20 味の素株式会社 L-アミノ酸の製造法
JP2016165225A (ja) 2013-07-09 2016-09-15 味の素株式会社 有用物質の製造方法
JP2016192903A (ja) 2013-09-17 2016-11-17 味の素株式会社 海藻由来バイオマスからのl−アミノ酸の製造方法
JP6569530B2 (ja) 2013-10-02 2019-09-04 味の素株式会社 ヘパロサン生産細菌及びヘパロサンの製造法
RU2013146377A (ru) 2013-10-17 2015-04-27 Закрытое акционерное общество "Научно-исследовательский институт Аджиномото-Генетика" (ЗАО "АГРИ") СПОСОБ ПОЛУЧЕНИЯ ИЗОПРЕНА С ИСПОЛЬЗОВАНИЕМ БАКТЕРИИ РОДА Bacillus
EP2886651B1 (de) 2013-10-21 2018-08-22 Ajinomoto Co., Inc. Verfahren zur herstellung von l-aminosäure
WO2015060391A1 (ja) 2013-10-23 2015-04-30 味の素株式会社 目的物質の製造法
WO2015115612A1 (ja) 2014-01-31 2015-08-06 味の素株式会社 変異型グルタミン酸-システインリガーゼ、及び、γ-グルタミルバリルグリシンの製造法
JP2017216881A (ja) 2014-12-26 2017-12-14 味の素株式会社 ジカルボン酸の製造方法
CN108350412B (zh) 2015-10-27 2022-02-11 味之素株式会社 用于生产醛的方法
JP6623690B2 (ja) 2015-10-30 2019-12-25 味の素株式会社 グルタミン酸系l−アミノ酸の製造法
CN108463555A (zh) 2016-01-12 2018-08-28 味之素株式会社 生产苯甲醛的方法
CN109937258B (zh) 2016-10-21 2023-06-23 味之素株式会社 蛋白质的分泌产生方法
AU2017347016B2 (en) 2016-10-21 2021-09-23 Ajinomoto Co., Inc. Secretory production method for protein
JP7074133B2 (ja) 2016-10-26 2022-05-24 味の素株式会社 目的物質の製造方法
EP3532626B1 (de) 2016-10-26 2023-08-30 Ajinomoto Co., Inc. Verfahren zur herstellung von einer zielsubstanz
JP7188385B2 (ja) 2016-10-26 2022-12-13 味の素株式会社 L-メチオニンまたは合成にs-アデノシルメチオニンを要求する代謝物の製造方法
EP3532628B1 (de) 2016-10-26 2024-02-28 Ajinomoto Co., Inc. Verfahren zur herstellung einer zielsubstanz
JP2019531759A (ja) 2016-10-26 2019-11-07 味の素株式会社 目的物質の製造方法
EP3532610B1 (de) 2016-10-27 2023-09-27 Ajinomoto Co., Inc. Verfahren zur herstellung von aldehyd
JP7066977B2 (ja) 2017-04-03 2022-05-16 味の素株式会社 L-アミノ酸の製造法
US10858676B2 (en) 2017-05-22 2020-12-08 Ajinomoto Co., Inc. Method for producing objective substance
WO2019059404A1 (ja) 2017-09-25 2019-03-28 味の素株式会社 タンパク質の製造法および二糖の製造法
US11680279B2 (en) 2017-11-29 2023-06-20 Ajinomoto Co., Inc. Method for producing objective substance
JP7124338B2 (ja) 2018-02-27 2022-08-24 味の素株式会社 変異型グルタチオン合成酵素、及び、γ-グルタミルバリルグリシンの製造法
WO2019194279A1 (en) 2018-04-06 2019-10-10 Ajinomoto Co., Inc. AGRICULTURAL OR HORTICULTURAL COMPOSITION CONTAINING CULTURE BROTH OF Bacillus BACTERIUM
EP3783106A4 (de) 2018-04-20 2022-01-05 Ajinomoto Co., Inc. Verfahren zur sekretorischen herstellung eines proteins
WO2020027251A1 (en) 2018-08-03 2020-02-06 Ajinomoto Co., Inc. Method for producing objective substance
EP3861109A1 (de) 2018-10-05 2021-08-11 Ajinomoto Co., Inc. Verfahren zur herstellung einer zielsubstanz durch bakterielle fermentation
CN112930359A (zh) 2018-10-25 2021-06-08 味之素株式会社 蛋白质的分泌生产方法
EP3960870A4 (de) 2019-03-29 2023-06-07 Ajinomoto Co., Inc. Verfahren zur herstellung von allolactose
EP3967676A4 (de) 2019-05-08 2023-02-08 Ajinomoto Co., Inc. Verfahren zur herstellung von vanillin
WO2021085405A1 (ja) 2019-10-28 2021-05-06 味の素株式会社 ベンズアルデヒドの製造方法
EP4115740A4 (de) 2020-03-04 2024-04-03 Ajinomoto Co., Inc. Mutante transglutaminase
JPWO2022071061A1 (de) 2020-09-29 2022-04-07
KR20230092008A (ko) 2020-10-28 2023-06-23 아지노모토 가부시키가이샤 L-아미노산의 제조법
CN117157394A (zh) 2021-04-16 2023-12-01 因比奥斯公司 发酵生产
WO2023282315A1 (ja) 2021-07-07 2023-01-12 味の素株式会社 非天然アミノ酸含有タンパク質の分泌生産法
EP4509613A1 (de) 2022-04-15 2025-02-19 Ajinomoto Co., Inc. Verfahren zur herstellung von kultiviertem fleisch
US20240117393A1 (en) 2022-09-30 2024-04-11 Ajinomoto Co., Inc. Method for producing l-amino acid
WO2024172163A1 (ja) 2023-02-16 2024-08-22 味の素株式会社 タンパク質の分泌生産法
EP4692312A1 (de) 2023-12-28 2026-02-11 Ajinomoto Co., Inc. L-glutaminsäure produzierendes bakterium und verfahren zur herstellung von l-glutaminsäure
EP4692313A1 (de) 2023-12-28 2026-02-11 Ajinomoto Co., Inc. L-glutaminsäure produzierendes bakterium und verfahren zur herstellung von l-glutaminsäure

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS55156591A (en) * 1979-05-23 1980-12-05 Ajinomoto Co Inc Method for stabilizing property of bacteria containing plasmid
EP0091723B1 (de) * 1982-02-17 1989-07-26 Imperial Chemical Industries Plc Vektor system
US4670388A (en) * 1982-12-30 1987-06-02 Carnegie Institution Of Washington Method of incorporating DNA into genome of drosophila
JPS59205983A (ja) * 1983-04-28 1984-11-21 ジエネツクス・コ−ポレイシヨン 異種遺伝子を原核微生物で発現させる方法
FR2563533B1 (fr) * 1984-04-27 1986-08-22 Centre Nat Rech Scient Procede d'amplification de l'expression d'un gene determine chez bacillus subtilis et souches obtenues
DE3572688D1 (en) * 1984-06-26 1989-10-05 Agronomique Inst Nat Rech Transformation vector for yeast yarrowia lipolytica, transformation process and transformed yeast
US4713337A (en) * 1985-01-03 1987-12-15 Massachusetts Institute Of Technology Method for deletion of a gene from a bacteria
FR2580233B1 (fr) * 1985-04-12 1988-11-25 Rhone Alpes Projets Plast Procede pour rendre une matiere plastique sensible au rayon laser et permettre son marquage au laser et article obtenu notamment pour le marquage des animaux
AU590558B2 (en) * 1985-04-30 1989-11-09 Monsanto Company Plant-colonizing microorganisms containing the toxin gene of b. thuringiensis as a chromosomal insertion
WO1988001646A1 (en) * 1986-08-26 1988-03-10 Allelix Inc. Universal system for transposon mutagenesis

Also Published As

Publication number Publication date
DE68927486T2 (de) 1997-07-03
ES2097115T3 (es) 1997-04-01
JPH02109985A (ja) 1990-04-23
JP2944094B2 (ja) 1999-08-30
AU624353B2 (en) 1992-06-11
EP0332488B1 (de) 1996-11-27
EP0332488A1 (de) 1989-09-13
AU3015489A (en) 1989-08-24
DK78989A (da) 1989-08-22
FR2627508A1 (fr) 1989-08-25
CA1341190C (fr) 2001-02-27
US5595889A (en) 1997-01-21
KR930007579B1 (ko) 1993-08-13
DK175477B1 (da) 2004-11-08
DE68927486D1 (de) 1997-01-09
DK78989D0 (da) 1989-02-21
KR890013183A (ko) 1989-09-21
FR2627508B1 (fr) 1990-10-05

Similar Documents

Publication Publication Date Title
ATE145668T1 (de) Verfahren zur integration eines bestimmten gens ins bakterielle chromosom und durch dieses verfahren erhaltenes bakterium
BG42526A3 (bg) Метод за получаване на полипептид чрез експресия в бактерий на структурен ген
HUP9802666A2 (hu) Eljárás L-lizin termelésére
AU524856B2 (en) Method of making a selected protein
ATE219499T1 (de) Lipopeptid-derivate, verfahren zu ihrer herstellung und ihre verwendung
ATE130314T1 (de) Bazillus subtilis mutant und verfahren zur herstellung von surfactin durch verwendung dieses mutants.
HUP9904162A2 (hu) Mutáns G-penicillin-acilázok
IL133832A0 (en) Vector for expression of heterologous protein and methods for extracting recombinant protein and for purifying isolated recombinant insulin
HUP9901395A2 (hu) Robbanóanyagok kimutatása és biodegradálása
AU655797B2 (en) Process for the genetic manipulation of myxobacteria
EP0196223A3 (en) Dedicated ribosomes and their use in producing protein in cell culture
DE59209916D1 (de) Verfahren zur Zellisolierung, isolierte Zellen (dsm 6314 und dsm 6418) und Verwendung isolierter Zellen zur Polysaccharidherstellung
ATE186737T1 (de) Ein verbessertes verfahren für die herstellung von seitenketten-derivaten von cyclohexapeptidyl- lipopeptiden
DE59109155D1 (de) Verfahren zur herstellung von vakzinen und ihre verwendung
DE59606386D1 (de) Verfahren zur herstellung von optisch aktiven aminen
KR910014398A (ko) 항생제 데옥시물룬도칸딘, 이의 제조방법 및 약제로서의 이의 용도
FR2492403B1 (de)
SE9201544L (sv) Saett att framstaella glykosyltransferaser
DE3884741D1 (de) Mikrobiologisches Verfahren zur Herstellung von UK-61.689 und Mikroorganismen zur Verwendung darin.
ATE142254T1 (de) Mutanter stamm von xanthomonas campestris, verfahren zur herstellung von xanthan und nichtviskoser xanthan
ATE124285T1 (de) Verfahren zur biologischen abluftreinigung.
Straley et al. Regulation by Ca super (2+) in the Yersinia low-Ca super (2+) response.
DE69213680D1 (de) Neues Verfahren zur Herstellung von 20-Oxo, 17-Alpha, 21-Dihydroxy Derivaten von Pregnan und neue Zwischenprodukte dafür
ATE27281T1 (de) Verfahren zur herstellung von oxanosin.
ATE169908T1 (de) Verfahren zur herstellung von gegebenenfalls 2- substituierten 5-chlorimidazol-4-carbaldehyden

Legal Events

Date Code Title Description
RER Ceased as to paragraph 5 lit. 3 law introducing patent treaties