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DNA, která obsahuje gen kódující aspartokinézu III, mikroorganizmus Escherichia coli a způsob výroby L-threoninu fermentací
Abstract
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DNA, která obsahuje gen, který ko'duje aspartokinázu III původem z bakterie Escherichia a který má v ko'dovacíí oblasti mutaci, která uvolňuje zpětnovazebnou inhibici způsobenou lysinem na zmíněné aspartokináze III, rekombinované DNA, čímž je míněna DNA spojená s vektorem DNA schopným autonomní replikace v bakterii Escherichia, mikroorganismus patřící k rodu Escherichia, který byl transformován vnesením výše uvedené rekombinované DNA do jeho buňky a metoda pro produkci L-threoninu, která zahrnuje kultivaci mikroorganismu ve fermantačním prostředí, produkci a shromažďování L-thereoninu v kultivačním prostředí, a sběr L-threoninu ze zmíněného kultivačního prostředí. Byly získány geny AK III pocházející z bakterií Escherichia, které dostatečně uvolňují zpětnovazebnou inhibici způsobenou lysinem. Vnesení těchto genů do bakterií, které produkují threonin, způsobí vznik nových bakterií, které produkují threonin daleko lépe než předchozí bakterie. Použití těchto bakterií, které produkují threŕ
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CZ285453B6
Czechia
Patent specification
- Other languages
English - Inventor
Konosuke Sano Hiroyuki Kojima Yuri Ogawa
Worldwide applications
1993
DE
SK
WO
CZ
ES
DK
JP
RU
EP
US
AT
1994
CN
Application number: DE69330518T
Filing date: 1993-11-10
Legal status: Expired - Lifetime
Application number: SK819-94A
Filing date: 1993-11-10
Legal status: IP Right Cessation
Application number: PCT/JP1993/001640
Filing date: 1993-11-10
Legal status: IP Right Grant
Application number: CZ941658A
Filing date: 1993-11-10
Legal status: IP Right Cessation
Application number: ES93924805T
Filing date: 1993-11-10
Legal status: Expired - Lifetime
Application number: DK93924805T
Filing date: 1993-11-10
Legal status:
Application number: JP51192494A
Filing date: 1993-11-10
Legal status: Expired - Fee Related
Application number: RU94035744A
Filing date: 1993-11-10
Legal status: IP Right Cessation
Application number: EP93924805A
Filing date: 1993-11-10
Legal status: Expired - Lifetime
Application number: US08/256,136
Filing date: 1993-11-10
Legal status: Expired - Lifetime
Application number: AT93924805T
Filing date: 1993-11-10
Legal status: IP Right Cessation
Application number: CN94102007A
Filing date: 1994-02-15
Legal status: Expired - Fee Related
Application CZ941658A events
A timeline of key events for this patent application, including priority claims,
publications, legal status, reassignments, and litigation.
Google has not performed a legal analysis and makes no representation as to the accuracy or completeness of the events listed.
Google has not performed a legal analysis and makes no representation as to the accuracy or completeness of the events listed.
1993-11-10
1994-12-15
1999-08-11
Description
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Patent Citations (7)
Publication number
Priority date
Publication date
Assignee
Title
Family To Family Citations
* Cited by examiner, † Cited by third party
Cited By (113)
Publication number
Priority date
Publication date
Assignee
Title
Family To Family Citations
* Cited by examiner, † Cited by third party, ‡ Family to family citation
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Title
Priority And Related Applications
Applications Claiming Priority (3)
Application
Filing date
Title
JP30002192
1992-11-10
Legal Events
Date
Code
Title
Description
2000-06-30
IF00
In force as of 2000-06-30 in czech republic
2012-06-20
MM4A
Patent lapsed due to non-payment of fee
Effective date: 20111110
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