DE68908111D1 - Spritzenfuehrung mit einstellung der einstichtiefe der nadel in die haut. - Google Patents

Spritzenfuehrung mit einstellung der einstichtiefe der nadel in die haut.

Info

Publication number
DE68908111D1
DE68908111D1 DE8989403027T DE68908111T DE68908111D1 DE 68908111 D1 DE68908111 D1 DE 68908111D1 DE 8989403027 T DE8989403027 T DE 8989403027T DE 68908111 T DE68908111 T DE 68908111T DE 68908111 D1 DE68908111 D1 DE 68908111D1
Authority
DE
Germany
Prior art keywords
needle
skin
adjusting
syringe guide
syringe
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE8989403027T
Other languages
English (en)
Inventor
Tino Dalto
Claude Laruelle
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Individual
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Application granted granted Critical
Publication of DE68908111D1 publication Critical patent/DE68908111D1/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/46—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests having means for controlling depth of insertion

Landscapes

  • Health & Medical Sciences (AREA)
  • Vascular Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Anesthesiology (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Hematology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Infusion, Injection, And Reservoir Apparatuses (AREA)
DE8989403027T 1988-11-03 1989-11-03 Spritzenfuehrung mit einstellung der einstichtiefe der nadel in die haut. Expired - Lifetime DE68908111D1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR8815375A FR2638359A1 (fr) 1988-11-03 1988-11-03 Guide de seringue avec reglage de la profondeur de penetration de l'aiguille dans la peau

Publications (1)

Publication Number Publication Date
DE68908111D1 true DE68908111D1 (de) 1993-09-09

Family

ID=9372222

Family Applications (1)

Application Number Title Priority Date Filing Date
DE8989403027T Expired - Lifetime DE68908111D1 (de) 1988-11-03 1989-11-03 Spritzenfuehrung mit einstellung der einstichtiefe der nadel in die haut.

Country Status (12)

Country Link
US (1) US5141496A (de)
EP (1) EP0371838B1 (de)
JP (1) JPH03503497A (de)
KR (1) KR900701340A (de)
AT (1) ATE92346T1 (de)
AU (1) AU627795B2 (de)
BR (1) BR8907144A (de)
CA (1) CA2002103A1 (de)
DE (1) DE68908111D1 (de)
FR (1) FR2638359A1 (de)
RU (1) RU1836110C (de)
WO (1) WO1990004988A1 (de)

Families Citing this family (450)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5282793A (en) * 1989-10-02 1994-02-01 Larson Eldon E Syringe holder and applicator
WO1993009723A1 (en) * 1991-11-12 1993-05-27 Ramel Urs A Lancet device
US6290683B1 (en) * 1992-04-29 2001-09-18 Mali-Tech Ltd. Skin piercing needle assembly
US6350274B1 (en) 1992-05-11 2002-02-26 Regen Biologics, Inc. Soft tissue closure systems
US5326350A (en) * 1992-05-11 1994-07-05 Li Shu Tung Soft tissue closure systems
TW404844B (en) * 1993-04-08 2000-09-11 Oxford Biosciences Ltd Needleless syringe
US5437645A (en) * 1993-10-08 1995-08-01 United States Surgical Corporation Surgical instrument positioning device
US5472427A (en) * 1993-10-22 1995-12-05 Rammler; David H. Trocar device
US5425718A (en) * 1993-10-22 1995-06-20 Tay; Sew-Wah Self-sticking needle assembly and method for insertion into an artery
US5899880A (en) * 1994-04-08 1999-05-04 Powderject Research Limited Needleless syringe using supersonic gas flow for particle delivery
US5540657A (en) * 1994-07-15 1996-07-30 Collagen Corporation Delivery device for injectable materials
US5478315A (en) * 1994-08-08 1995-12-26 Brothers Family Investments, L.C. Local anesthetic injection system
US5480389A (en) * 1994-08-09 1996-01-02 Becton, Dickinson And Company Method and apparatus for adjusting the length of a combined spinal-epidural needle
SE9502285D0 (sv) * 1995-06-22 1995-06-22 Pharmacia Ab Improvements related to injections
US5657718A (en) * 1995-08-23 1997-08-19 Elfstar, L.L.C. Method of feeding fish
US5836914A (en) * 1995-09-15 1998-11-17 Becton Dickinson And Company Method and apparatus for variably regulating the length of a combined spinal-epidural needle
US5632730A (en) * 1995-10-16 1997-05-27 Reinert; Charles B. Fluid injector
US5609577A (en) * 1996-01-29 1997-03-11 Haber; Terry M. Automatically locking hypodermic needle hiding shield for a dose metering syringe
US6629959B2 (en) 1996-02-27 2003-10-07 Injectimed, Inc. Needle tip guard for percutaneous entry needles
AU3335697A (en) * 1996-07-05 1998-02-02 Novo Nordisk A/S Automatic needle insertion mechanism
US5906594A (en) 1997-01-08 1999-05-25 Symbiosis Corporation Endoscopic infusion needle having dual distal stops
US6607509B2 (en) * 1997-12-31 2003-08-19 Medtronic Minimed, Inc. Insertion device for an insertion set and method of using the same
US20070142776A9 (en) * 1997-02-05 2007-06-21 Medtronic Minimed, Inc. Insertion device for an insertion set and method of using the same
US5851197A (en) * 1997-02-05 1998-12-22 Minimed Inc. Injector for a subcutaneous infusion set
US6093172A (en) * 1997-02-05 2000-07-25 Minimed Inc. Injector for a subcutaneous insertion set
US5931347A (en) * 1997-05-23 1999-08-03 Haubrich; Mark A. Dispenser unit for viscous substances
US6482176B1 (en) * 1997-11-27 2002-11-19 Disetronic Licensing Ag Method and device for controlling the introduction depth of an injection needle
CA2229522A1 (en) 1998-04-15 1999-10-15 Thomas Randall Inkpen Needle aid
US6263880B1 (en) * 1998-06-22 2001-07-24 Neovasys, Inc. Method of enhancing blood flow in tissue
JP2000287915A (ja) * 1999-04-08 2000-10-17 Machida Endscope Co Ltd 手術用案内管装置
WO2000061209A1 (en) * 1999-04-14 2000-10-19 Thomas Randall Inkpen Needle injection-facilitating device
US7192713B1 (en) 1999-05-18 2007-03-20 President And Fellows Of Harvard College Stabilized compounds having secondary structure motifs
US6569143B2 (en) 1999-10-14 2003-05-27 Becton, Dickinson And Company Method of intradermally injecting substances
US6569123B2 (en) 1999-10-14 2003-05-27 Becton, Dickinson And Company Prefillable intradermal injector
US7241275B2 (en) * 1999-10-14 2007-07-10 Becton, Dickinson And Company Intradermal needle
US20020193740A1 (en) 1999-10-14 2002-12-19 Alchas Paul G. Method of intradermally injecting substances
US6494865B1 (en) 1999-10-14 2002-12-17 Becton Dickinson And Company Intradermal delivery device including a needle assembly
US6776776B2 (en) * 1999-10-14 2004-08-17 Becton, Dickinson And Company Prefillable intradermal delivery device
US6843781B2 (en) * 1999-10-14 2005-01-18 Becton, Dickinson And Company Intradermal needle
GB0006263D0 (en) * 2000-03-15 2000-05-03 Powderject Res Ltd Apparatus and method for adjusting the characteristics of a needleless syringe
US20020104808A1 (en) * 2000-06-30 2002-08-08 Lou Blasetti Method and apparatus for producing platelet rich plasma and/or platelet concentrate
US7008433B2 (en) 2001-02-15 2006-03-07 Depuy Acromed, Inc. Vertebroplasty injection device
EP2269639B1 (de) * 2001-02-23 2018-11-28 GlaxoSmithKline Biologicals s.a. Influenza Vakzinzusammensetzungen zur intradermaler Verabreichung
GB0109297D0 (en) 2001-04-12 2001-05-30 Glaxosmithkline Biolog Sa Vaccine
US20100221284A1 (en) 2001-05-30 2010-09-02 Saech-Sisches Serumwerk Dresden Novel vaccine composition
MY134424A (en) 2001-05-30 2007-12-31 Saechsisches Serumwerk Stable influenza virus preparations with low or no amount of thiomersal
US20060018877A1 (en) * 2001-06-29 2006-01-26 Mikszta John A Intradermal delivery of vacccines and therapeutic agents
MXPA03011611A (es) * 2001-06-29 2004-07-01 Becton Dickinson Co Administracion intradermica de vacunas y agentes terapeuticos genicos a traves de microcanula.
US8061006B2 (en) * 2001-07-26 2011-11-22 Powderject Research Limited Particle cassette, method and kit therefor
US6830562B2 (en) 2001-09-27 2004-12-14 Unomedical A/S Injector device for placing a subcutaneous infusion set
ITTO20011228A1 (it) 2001-12-28 2003-06-28 Cane Srl Contenitore per ago monouso.
DE60304681T2 (de) 2002-02-12 2007-01-25 Unomedical A/S Infusionsvorrichtung mit nadelschutzhülse
US6912417B1 (en) 2002-04-05 2005-06-28 Ichor Medical Systmes, Inc. Method and apparatus for delivery of therapeutic agents
US20040051019A1 (en) 2002-09-02 2004-03-18 Mogensen Lasse Wesseltoft Apparatus for and a method of adjusting the length of an infusion tube
EP1554008B1 (de) 2002-09-02 2008-12-31 Unomedical A/S Vorrichtung zur subkutanen verabreichung eines medikaments an einen patienten
DE60317231T2 (de) 2002-09-02 2008-08-14 Unomedical A/S Vorrichtung und Verfahren zur Einstellung der Länge eines Infusionsschlauchs
US7115112B2 (en) 2002-09-02 2006-10-03 Unomedical A/S Device for subcutaneous administration of a medicament to a patient and tubing for same
DK200201823A (da) 2002-11-26 2004-05-27 Maersk Medical As Forbindelsesstykke for en slangeforbindelse
US8267890B2 (en) 2003-01-30 2012-09-18 Becton, Dickinson And Company Intradermal delivery device with contoured skin engaging surface geometry
WO2004069302A2 (en) * 2003-01-30 2004-08-19 Becton, Dickinson And Company Holder with safety shield for a drug delivery device
US20040158202A1 (en) 2003-02-12 2004-08-12 Soren Jensen Cover
AU2003214708A1 (en) 2003-03-14 2004-09-30 Roque Humberto Ferreyro Irigoyen Hydraulic device for the injection of bone cement in percutaneous vertebroplasty
US8066713B2 (en) 2003-03-31 2011-11-29 Depuy Spine, Inc. Remotely-activated vertebroplasty injection device
US7070580B2 (en) 2003-04-01 2006-07-04 Unomedical A/S Infusion device and an adhesive sheet material and a release liner
EP1664322B1 (de) 2003-05-22 2013-07-10 Fraunhofer USA, Inc. Rekombinantes trägermolekül zur expression, zuführung und reinigung von zielpolypeptiden
US8415407B2 (en) 2004-03-21 2013-04-09 Depuy Spine, Inc. Methods, materials, and apparatus for treating bone and other tissue
MXPA06002047A (es) 2003-08-28 2006-05-25 Becton Dickinson Co Dispositivo de inyeccion intradermico.
WO2005034949A1 (en) * 2003-09-09 2005-04-21 University Of Florida Desferrithiocin derivatives and their use as iron chelators
IL157981A (en) 2003-09-17 2014-01-30 Elcam Medical Agricultural Cooperative Ass Ltd Auto injector
US8579908B2 (en) 2003-09-26 2013-11-12 DePuy Synthes Products, LLC. Device for delivering viscous material
US8147426B2 (en) * 2003-12-31 2012-04-03 Nipro Diagnostics, Inc. Integrated diagnostic test system
EP3466483A1 (de) 2004-03-08 2019-04-10 Ichor Medical Systems Inc. Verbessertes gerät für die elektrisch vermittelte abgabe von therapeutika
IL160891A0 (en) 2004-03-16 2004-08-31 Auto-mix needle
US8221355B2 (en) 2004-03-26 2012-07-17 Unomedical A/S Injection device for infusion set
GB2414406B (en) * 2004-05-28 2009-03-18 Cilag Ag Int Injection device
GB2414401B (en) 2004-05-28 2009-06-17 Cilag Ag Int Injection device
GB2414400B (en) 2004-05-28 2009-01-14 Cilag Ag Int Injection device
GB2414403B (en) * 2004-05-28 2009-01-07 Cilag Ag Int Injection device
GB2414409B (en) 2004-05-28 2009-11-18 Cilag Ag Int Injection device
GB2414402B (en) 2004-05-28 2009-04-22 Cilag Ag Int Injection device
GB2414399B (en) 2004-05-28 2008-12-31 Cilag Ag Int Injection device
GB2414775B (en) 2004-05-28 2008-05-21 Cilag Ag Int Releasable coupling and injection device
EP1786343B1 (de) 2004-07-30 2012-05-02 Depuy Spine, Inc. Gerät zur behandlung von knochen und anderem gewebe
US8062250B2 (en) 2004-08-10 2011-11-22 Unomedical A/S Cannula device
KR100689516B1 (ko) * 2004-09-15 2007-03-02 삼성전자주식회사 멀티미디어 방송/멀티캐스트 서비스 시스템에서 선호주파수정보의 전달 방법 및 장치
WO2007001448A2 (en) 2004-11-04 2007-01-04 Massachusetts Institute Of Technology Coated controlled release polymer particles as efficient oral delivery vehicles for biopharmaceuticals
JP4964141B2 (ja) 2004-12-10 2012-06-27 ウノメディカル アクティーゼルスカブ 挿入具
US7985199B2 (en) 2005-03-17 2011-07-26 Unomedical A/S Gateway system
TW200722101A (en) 2005-03-23 2007-06-16 Glaxosmithkline Biolog Sa Novel composition
BRPI0610644B8 (pt) 2005-04-04 2021-05-25 Univ Florida composto e composição farmacêutica que compreende tal composto e um veículo ou diluente farmaceuticamente aceitável.
GB2424838B (en) 2005-04-06 2011-02-23 Cilag Ag Int Injection device (adaptable drive)
GB2424836B (en) 2005-04-06 2010-09-22 Cilag Ag Int Injection device (bayonet cap removal)
GB2424835B (en) 2005-04-06 2010-06-09 Cilag Ag Int Injection device (modified trigger)
GB2425062B (en) 2005-04-06 2010-07-21 Cilag Ag Int Injection device
GB2427826B (en) 2005-04-06 2010-08-25 Cilag Ag Int Injection device comprising a locking mechanism associated with integrally formed biasing means
DE102005025639B4 (de) * 2005-06-03 2011-04-07 Innovacell Biotechnologie Gmbh Injektionsvorrichtung
MX2007016062A (es) 2005-06-28 2008-03-10 Unomedical As Empaquetamiento para juego de infusion y metodo para aplicar un juego de infusion.
US9381024B2 (en) 2005-07-31 2016-07-05 DePuy Synthes Products, Inc. Marked tools
US9918767B2 (en) 2005-08-01 2018-03-20 DePuy Synthes Products, Inc. Temperature control system
AU2006341615A1 (en) * 2005-08-03 2007-10-18 Fraunhofer Usa, Inc. Compositions and methods for production of immunoglobulins
DK1759729T3 (da) 2005-08-30 2010-04-19 Cilag Gmbh Int Nåleindretning til en forfyldt sprøjte
DE602005023458D1 (de) 2005-09-12 2010-10-21 Unomedical As Einfürungssystem für ein Infusionsset mit einem ersten und zweiten Federeinheit
US20110098656A1 (en) 2005-09-27 2011-04-28 Burnell Rosie L Auto-injection device with needle protecting cap having outer and inner sleeves
US8360629B2 (en) 2005-11-22 2013-01-29 Depuy Spine, Inc. Mixing apparatus having central and planetary mixing elements
USD655807S1 (en) 2005-12-09 2012-03-13 Unomedical A/S Medical device
TWI457133B (zh) 2005-12-13 2014-10-21 Glaxosmithkline Biolog Sa 新穎組合物
US9267937B2 (en) 2005-12-15 2016-02-23 Massachusetts Institute Of Technology System for screening particles
ATE492309T1 (de) 2005-12-23 2011-01-15 Unomedical As Injektionsvorrichtung
US8277816B2 (en) * 2006-02-13 2012-10-02 Fraunhofer Usa, Inc. Bacillus anthracis antigens, vaccine compositions, and related methods
AU2007215080A1 (en) * 2006-02-13 2007-08-23 Fraunhofer Usa, Inc. Influenza antigens, vaccine compositions, and related methods
KR20080106434A (ko) * 2006-02-13 2008-12-05 프라운호퍼 유에스에이, 인코포레이티드 Ｈｐｖ 항원, 백신 조성물 및 관련된 방법
NZ570115A (en) 2006-02-28 2010-07-30 Unomedical As Inserter for infusion part and infusion part provided with needle protector
CA2644694C (en) * 2006-03-10 2014-05-13 Sangeeta N. Bhatia Triggered self-assembly conjugates and nanosystems
US7666912B2 (en) 2006-03-23 2010-02-23 Massachusetts Eye And Ear Infirmary Compositions and methods for reducing body fat
CA2648099C (en) 2006-03-31 2012-05-29 The Brigham And Women's Hospital, Inc System for targeted delivery of therapeutic agents
US20090325944A1 (en) * 2006-04-12 2009-12-31 Suzanne Walker Kahne Methods and Compositions for Modulating Glycosylation
CN101573141B (zh) 2006-05-15 2016-05-04 麻省理工学院 用于功能性颗粒的聚合物
GB2438590B (en) 2006-06-01 2011-02-09 Cilag Gmbh Int Injection device
GB2438591B (en) 2006-06-01 2011-07-13 Cilag Gmbh Int Injection device
GB2438593B (en) 2006-06-01 2011-03-30 Cilag Gmbh Int Injection device (cap removal feature)
CA2656298A1 (en) 2006-06-02 2007-12-13 President And Fellows Of Harvard College Protein surface remodeling
EP2023818A2 (de) 2006-06-07 2009-02-18 Unomedical A/S Einführinstrument für einen transkutanen sensor
WO2007140785A1 (en) 2006-06-09 2007-12-13 Unomedical A/S Mounting pad
WO2007150030A2 (en) 2006-06-23 2007-12-27 Massachusetts Institute Of Technology Microfluidic synthesis of organic nanoparticles
DK2043682T3 (da) 2006-07-17 2014-06-02 Glaxosmithkline Biolog Sa Influenzavaccine
MX2009001119A (es) 2006-08-02 2009-06-02 Unomedical As Canula y dispositivo de administracion.
WO2008021367A2 (en) * 2006-08-11 2008-02-21 President And Fellows Of Harvard College Moenomycin biosynthesis-related compositions and methods of use thereof
AU2007284496A1 (en) * 2006-08-14 2008-02-21 Massachusetts Institute Of Technology Glycan data mining system
US20090269342A1 (en) * 2006-08-14 2009-10-29 Massachusetts Institute Of Technology Hemagglutinin Polypeptides, and Reagents and Methods Relating Thereto
EP2068898A4 (de) 2006-09-14 2011-07-20 Depuy Spine Inc Knochenzement und anwendungsverfahren dafür
JO3598B1 (ar) 2006-10-10 2020-07-05 Infinity Discovery Inc الاحماض والاسترات البورونية كمثبطات اميد هيدروليز الحامض الدهني
WO2008047371A2 (en) 2006-10-19 2008-04-24 Depuy Spine, Inc. Fluid delivery system
EP1917990A1 (de) 2006-10-31 2008-05-07 Unomedical A/S Infusionsset
JP2010528981A (ja) 2006-12-01 2010-08-26 アンテリオス， インコーポレイテッド 両親媒性実体ナノ粒子
WO2008073856A2 (en) * 2006-12-08 2008-06-19 Massachusetts Institute Of Technology Delivery of nanoparticles and/or agents to cells
PT2114873E (pt) * 2006-12-26 2013-05-06 Lantheus Medical Imaging Inc Ligandos para imagiologia de inervação cardíaca
JP5649825B2 (ja) 2007-01-31 2015-01-07 デイナ ファーバー キャンサー インスティチュート，インコーポレイテッド 安定化させたｐ５３ペプチドおよびその使用法
WO2008098165A2 (en) 2007-02-09 2008-08-14 Massachusetts Institute Of Technology Oscillating cell culture bioreactor
CN100457206C (zh) * 2007-03-07 2009-02-04 中国人民解放军第二军医大学 可调式搏动心肌内注入器
CN104003955A (zh) 2007-03-15 2014-08-27 佛罗里达大学研究基金公司 去铁硫辛聚醚类似物
US7960139B2 (en) 2007-03-23 2011-06-14 Academia Sinica Alkynyl sugar analogs for the labeling and visualization of glycoconjugates in cells
KR101525754B1 (ko) 2007-03-28 2015-06-09 프레지던트 앤드 펠로우즈 오브 하바드 칼리지 스티칭된 폴리펩티드
EP2144600A4 (de) 2007-04-04 2011-03-16 Massachusetts Inst Technology Poly (aminsäure)-zielmoleküle
WO2008124634A1 (en) 2007-04-04 2008-10-16 Massachusetts Institute Of Technology Polymer-encapsulated reverse micelles
WO2008134643A2 (en) * 2007-04-28 2008-11-06 Fraunhofer Usa, Inc. Trypanosoma antigens, vaccine compositions, and related methods
NZ580603A (en) * 2007-06-14 2013-02-22 Crucell Switzerland Ag Intradermal influenza vaccine
WO2008156676A1 (en) 2007-06-15 2008-12-24 President And Fellows Of Harvard College Methods and compositions for detecting and modulating o-glycosylation
AU2008266382B2 (en) 2007-06-20 2013-06-27 Unomedical A/S A catheter and a method and an apparatus for making such catheter
US8430850B2 (en) 2007-07-03 2013-04-30 Unomedical A/S Inserter having bistable equilibrium states
WO2009007287A1 (en) 2007-07-10 2009-01-15 Unomedical A/S Inserter having two springs
CA2692933C (en) * 2007-07-11 2016-10-18 Fraunhofer Usa, Inc. Yersinia pestis antigens, vaccine compositions, and related methods
EP2175913A1 (de) 2007-07-18 2010-04-21 Unomedical A/S Einsetzvorrichtung mit schwenkwirkung
BRPI0815662A2 (pt) * 2007-08-20 2016-09-27 Fraunhofer Usa Inc vacinas, antígenos, composições, e métodos profilácticos e terapêuticos para gripe
US8012120B2 (en) * 2007-09-13 2011-09-06 Avant Medical Corp. Device and method for the automatic initiation of an injection
AU2008302516B2 (en) * 2007-09-17 2013-09-19 Tecpharma Licensing Ag Insertion devices for infusion devices
US8604004B2 (en) * 2007-10-04 2013-12-10 President And Fellows Of Harvard College Moenomycin analogs, methods of synthesis, and uses thereof
EP2620157A3 (de) 2007-10-12 2013-10-16 Massachusetts Institute of Technology Impfstoffnanotechnologie
WO2009089119A2 (en) * 2008-01-03 2009-07-16 Massachusetts Institute Of Technology Decoy influenza therapies
US8193182B2 (en) 2008-01-04 2012-06-05 Intellikine, Inc. Substituted isoquinolin-1(2H)-ones, and methods of use thereof
MX2010008759A (es) 2008-02-13 2010-08-31 Unomedical As Sellado entre una parte de canula y una trayectoria de fluido.
EP2259816B1 (de) 2008-02-20 2015-10-21 Unomedical A/S Einführungsgerät mit horizontal beweglichem teil
TW201000107A (en) * 2008-04-09 2010-01-01 Infinity Pharmaceuticals Inc Inhibitors of fatty acid amide hydrolase
US20090270806A1 (en) * 2008-04-24 2009-10-29 Medtronic Vascular, Inc. Devices and Methods for Controlled-Depth Injection
CN102066405B (zh) * 2008-04-28 2015-09-30 哈佛大学校长及研究员协会 用于细胞穿透的超荷电蛋白
ES2677599T3 (es) * 2008-05-30 2018-08-03 Allergan, Inc. Dispositivo de inyección para rellenos de aumento de tejido blando, agentes bioactivos y otros materiales biocompatibles en forma líquida o de gel
GB2461086B (en) 2008-06-19 2012-12-05 Cilag Gmbh Int Injection device
GB2461087B (en) 2008-06-19 2012-09-26 Cilag Gmbh Int Injection device
GB2461089B (en) 2008-06-19 2012-09-19 Cilag Gmbh Int Injection device
GB2461088B (en) * 2008-06-19 2012-09-26 Cilag Gmbh Int Injection device
GB2461084B (en) 2008-06-19 2012-09-26 Cilag Gmbh Int Fluid transfer assembly
GB2461085B (en) 2008-06-19 2012-08-29 Cilag Gmbh Int Injection device
US20110212157A1 (en) 2008-06-26 2011-09-01 Anterios, Inc. Dermal delivery
EP2318832B1 (de) 2008-07-15 2013-10-09 Academia Sinica Glycan-arrays auf objektträgern mit ptfe-aluminiumbeschichtung und entsprechende verfahren
KR20110033304A (ko) * 2008-07-23 2011-03-30 메사추세츠 인스티튜트 오브 테크놀로지 Ｄｎａ 손상에 대해 보호하고 신경세포 생존을 증가시키는 히스톤 디아세틸라제 1 (ｈｄａｃ1)의 활성화
WO2010011313A2 (en) 2008-07-23 2010-01-28 President And Fellows Of Harvard College Ligation of stapled polypeptides
US20100047210A1 (en) * 2008-08-25 2010-02-25 Medtronic Vascular, Inc. Systems and Methods for Positioning of Needles and Other Devices Within Body Tissue
WO2010037046A1 (en) 2008-09-28 2010-04-01 Fraunhofer Usa, Inc. Humanized neuraminidase antibody and methods of use thereof
US8343497B2 (en) 2008-10-12 2013-01-01 The Brigham And Women's Hospital, Inc. Targeting of antigen presenting cells with immunonanotherapeutics
US8277812B2 (en) 2008-10-12 2012-10-02 Massachusetts Institute Of Technology Immunonanotherapeutics that provide IgG humoral response without T-cell antigen
US8591905B2 (en) 2008-10-12 2013-11-26 The Brigham And Women's Hospital, Inc. Nicotine immunonanotherapeutics
US8343498B2 (en) 2008-10-12 2013-01-01 Massachusetts Institute Of Technology Adjuvant incorporation in immunonanotherapeutics
WO2010065649A1 (en) * 2008-12-02 2010-06-10 Allergan, Inc. Injection device
EP2376619A4 (de) 2008-12-15 2012-07-04 Greenlight Biosciences Inc Verfahren zur flusssteuerung bei stoffwechselwegen
PL2384217T3 (pl) 2008-12-22 2021-08-02 Unomedical A/S Urządzenie medyczne zawierające podkładkę samoprzylepną
WO2010074760A1 (en) * 2008-12-22 2010-07-01 Greenlight Biosciences Compositions and methods for the production of a compound
AU2010234449A1 (en) 2009-04-07 2011-11-03 Infinity Pharmaceuticals, Inc. Inhibitors of fatty acid amide hydrolase
WO2010118155A1 (en) 2009-04-07 2010-10-14 Infinity Pharmaceuticals, Inc. Inhibitors of fatty acid amide hydrolase
WO2010129023A2 (en) 2009-04-28 2010-11-11 President And Fellows Of Harvard College Supercharged proteins for cell penetration
US8927551B2 (en) * 2009-05-18 2015-01-06 Infinity Pharmaceuticals, Inc. Isoxazolines as inhibitors of fatty acid amide hydrolase
US9149465B2 (en) * 2009-05-18 2015-10-06 Infinity Pharmaceuticals, Inc. Isoxazolines as inhibitors of fatty acid amide hydrolase
US8765735B2 (en) * 2009-05-18 2014-07-01 Infinity Pharmaceuticals, Inc. Isoxazolines as inhibitors of fatty acid amide hydrolase
EP2438046A4 (de) 2009-06-01 2013-04-17 Harvard College O-glcnac-transferasehemmer und verwendungen davon
JP2012532929A (ja) 2009-07-13 2012-12-20 プレジデント アンド フェロウズ オブ ハーバード カレッジ 二機能性のステープリングされたポリペプチドおよびそれらの使用
US8562567B2 (en) 2009-07-30 2013-10-22 Unomedical A/S Inserter device with horizontal moving part
CN102548598B (zh) 2009-08-07 2014-09-17 犹诺医药有限公司 具有传感器和一个或多个插管的传送装置
US20130072439A1 (en) 2009-09-22 2013-03-21 Huw M. Nash Peptidomimetic macrocycles
EP2483307A1 (de) 2009-09-29 2012-08-08 Fraunhofer USA, Inc. Influenza-hämagglutinin-antikörper, zusammensetzungen daraus und zugehörige verfahren
AU2010310941A1 (en) 2009-10-30 2012-05-17 F.Hoffmann-La Roche Ag Systems, methods and devices for adjusting the insertion depth of a cannula associated with a portable therapeutic device
US10087236B2 (en) 2009-12-02 2018-10-02 Academia Sinica Methods for modifying human antibodies by glycan engineering
US11377485B2 (en) 2009-12-02 2022-07-05 Academia Sinica Methods for modifying human antibodies by glycan engineering
US20110137260A1 (en) 2009-12-07 2011-06-09 Allergan, Inc. Slotted syringe
EP2519517B1 (de) 2009-12-29 2015-03-25 Dana-Farber Cancer Institute, Inc. Typ-ii-raf-kinase-hemmer
ES2802623T3 (es) 2010-01-27 2021-01-20 Massachusetts Inst Technology Agentes polipeptídicos técnicamente diseñados para la neutralización dirigida de amplio espectro de la gripe
MX361692B (es) 2010-02-03 2018-12-13 Infinity Pharmaceuticals Inc Inhibidores de amida hidrolasa de ácido graso.
EP2544674B1 (de) 2010-03-08 2017-10-25 Sloan Kettering Institute For Cancer Research Cdc7 kinase hemmer und deren verwendung
WO2011119549A1 (en) 2010-03-22 2011-09-29 President And Fellows Of Harvard College Trioxacarcins and uses thereof
CN102844060A (zh) 2010-03-30 2012-12-26 犹诺医药有限公司 医疗装置
WO2011130332A1 (en) 2010-04-12 2011-10-20 Academia Sinica Glycan arrays for high throughput screening of viruses
WO2011140296A1 (en) 2010-05-05 2011-11-10 Infinity Pharmaceuticals Triazoles as inhibitors of fatty acid synthase
CA2798330A1 (en) 2010-05-05 2011-11-10 Infinity Pharmaceuticals, Inc. Tetrazolones as inhibitors of fatty acid synthase
ES2718844T3 (es) 2010-05-07 2019-07-04 Greenlight Biosciences Inc Métodos para controlar el flujo en rutas metabólicas mediante la reubicación de enzimas
CA3041113C (en) 2010-05-11 2022-01-18 Lantheus Medical Imaging, Inc. Compositions, methods, and systems for the synthesis and use of imaging agents
CA2799394A1 (en) 2010-05-19 2011-11-24 Allergan, Inc. Modular injection device
US9193989B2 (en) 2010-06-18 2015-11-24 Taiho Pharmaceutical Co., Ltd. PRPK-TPRKB modulators and uses thereof
WO2012019168A2 (en) 2010-08-06 2012-02-09 Moderna Therapeutics, Inc. Engineered nucleic acids and methods of use thereof
CN108570097A (zh) 2010-08-13 2018-09-25 爱勒让治疗公司 拟肽大环化合物
EP3219796B1 (de) 2010-08-31 2020-10-07 GreenLight Biosciences, Inc. Verfahren zur flusssteuerung in stoffwechselwegen durch proteasemanipulation
WO2012040406A2 (en) 2010-09-21 2012-03-29 Massachusetts Institute Of Technology Influenza treatment and/or characterization; human-adapted ha polypeptides; vaccines
WO2012040459A2 (en) 2010-09-22 2012-03-29 President And Fellows Of Harvard College Beta-catenin targeting peptides and uses thereof
EP2433663A1 (de) 2010-09-27 2012-03-28 Unomedical A/S Einführsystem
DE19177059T1 (de) 2010-10-01 2021-10-07 Modernatx, Inc. N1-methyl-pseudouracile enthältendes ribonucleinsäuren sowie ihre verwendungen
RU2663718C2 (ru) 2010-10-04 2018-08-08 Массачусетс Инститьют Оф Текнолоджи Полипептиды гемагглютининов, а также связанные с ними реагенты и способы
EP2436412A1 (de) 2010-10-04 2012-04-04 Unomedical A/S Sprinklerkanüle
JP2013545749A (ja) 2010-11-10 2013-12-26 インフィニティー ファーマシューティカルズ， インコーポレイテッド 複素環化合物及びその使用
BR112013017670B1 (pt) 2011-01-10 2022-07-19 Infinity Pharmaceuticals, Inc Processos de preparação de isoquinolinonas e formas sólidas de isoquinolinonas
US9089579B2 (en) 2011-01-19 2015-07-28 Topokine Therapeutics, Inc. Methods and compositions for treating metabolic syndrome
KR102001050B1 (ko) 2011-01-24 2019-07-17 엘캠 메디컬 애그리컬처럴 코오퍼레이티브 어소시에이션 리미티드 인젝터
SG10201804552WA (en) 2011-01-24 2018-07-30 Anterios Inc Nanoparticle compositions, formulations thereof, and uses therefor
TR201905477T4 (tr) 2011-01-24 2019-05-21 Anterios Inc Nano-parçacık bileşimler.
WO2012103037A1 (en) 2011-01-24 2012-08-02 Anterios, Inc. Oil compositions
MX2013010076A (es) 2011-03-03 2014-04-07 Tersus Pharmaceuticals Llc Composiciones y metodos que comprenden c16:1n7 palmitoleato.
RU2457868C1 (ru) * 2011-03-17 2012-08-10 Федеральное государственное бюджетное учреждение "Медицинский радиологический научный центр" Министерства здравоохранения и социального развития РФ (ФГБУ МРНЦ Минздравсоцразвития России) Инъектор для введения лекарственных средств
EP2691396B1 (de) 2011-03-30 2016-08-10 Brown University Enopeptine, verwendungen davon und syntheseverfahren dafür
DE12722942T1 (de) 2011-03-31 2021-09-30 Modernatx, Inc. Freisetzung und formulierung von manipulierten nukleinsäuren
JP6061922B2 (ja) 2011-06-22 2017-01-18 ザ ジェネラル ホスピタル コーポレイション プロテイノパチーの処置方法
KR20140063605A (ko) 2011-07-19 2014-05-27 인피니티 파마슈티칼스, 인코포레이티드 헤테로사이클릭 화합물 및 그의 용도
WO2013012915A1 (en) 2011-07-19 2013-01-24 Infinity Pharmaceuticals Inc. Heterocyclic compounds and uses thereof
PL2734510T3 (pl) 2011-07-22 2019-05-31 Massachusetts Inst Technology Aktywatory deacetylaz histonowych klasy I (HDAC) i ich zastosowania
MX2014002542A (es) 2011-08-29 2014-07-09 Infinity Pharmaceuticals Inc Compuestos heterociclicos y usos de los mismos.
KR20190015765A (ko) 2011-09-09 2019-02-14 랜티우스 메디컬 이메징, 인크. 영상화제의 합성 및 사용을 위한 조성물, 방법 및 시스템
CN104093848A (zh) 2011-09-09 2014-10-08 绿光生物科学公司 碳青霉烯(carbapenem)的无细胞制备
WO2013039861A2 (en) 2011-09-12 2013-03-21 modeRNA Therapeutics Engineered nucleic acids and methods of use thereof
US9630979B2 (en) 2011-09-29 2017-04-25 Infinity Pharmaceuticals, Inc. Inhibitors of monoacylglycerol lipase and methods of their use
JP6113737B2 (ja) 2011-10-03 2017-04-12 モデルナティエックス インコーポレイテッドＭｏｄｅｒｎａＴＸ，Ｉｎｃ． 修飾型のヌクレオシド、ヌクレオチドおよび核酸、ならびにそれらの使用方法
WO2013050277A1 (en) 2011-10-05 2013-04-11 Unomedical A/S Inserter for simultaneous insertion of multiple transcutaneous parts
MX358886B (es) 2011-10-18 2018-08-31 Aileron Therapeutics Inc Macrociclos peptidomimeticos.
EP2583715A1 (de) 2011-10-19 2013-04-24 Unomedical A/S Infusionsschlauchsystem und Herstellungsverfahren
US9440051B2 (en) 2011-10-27 2016-09-13 Unomedical A/S Inserter for a multiplicity of subcutaneous parts
US9382239B2 (en) 2011-11-17 2016-07-05 Dana-Farber Cancer Institute, Inc. Inhibitors of c-Jun-N-terminal kinase (JNK)
US8603028B2 (en) 2011-11-18 2013-12-10 Allergan, Inc. Injection device having an angled tip portion
GB201120000D0 (en) 2011-11-20 2012-01-04 Glaxosmithkline Biolog Sa Vaccine
GB201119999D0 (en) 2011-11-20 2012-01-04 Glaxosmithkline Biolog Sa Vaccine
MX2014007233A (es) 2011-12-16 2015-02-04 Moderna Therapeutics Inc Composiciones de nucleosidos, nucleotidos y acidos nucleicos modificados.
CA2859406C (en) 2011-12-16 2020-08-25 University Of Florida Research Foundation, Inc. Uses of 4'-desferrithiocin analogs
US8426471B1 (en) 2011-12-19 2013-04-23 Topokine Therapeutics, Inc. Methods and compositions for reducing body fat and adipocytes
SG11201404648PA (en) 2012-02-15 2014-09-26 Aileron Therapeutics Inc Peptidomimetic macrocycles
US8987414B2 (en) 2012-02-15 2015-03-24 Aileron Therapeutics, Inc. Triazole-crosslinked and thioether-crosslinked peptidomimetic macrocycles
US9902985B2 (en) 2012-04-06 2018-02-27 President And Fellows Of Harvard College Chemoenzymatic methods for synthesizing moenomycin analogs
EP2850091A1 (de) 2012-04-06 2015-03-25 President and Fellows of Harvard College Verfahren und verbindungen zur identifizierung von glycosyltransferaseinhibitoren
US9273084B2 (en) 2012-04-06 2016-03-01 President And Fellows Of Harvard College Moenomycin analogs, methods of synthesis, and uses thereof
US8940742B2 (en) 2012-04-10 2015-01-27 Infinity Pharmaceuticals, Inc. Heterocyclic compounds and uses thereof
US10130714B2 (en) 2012-04-14 2018-11-20 Academia Sinica Enhanced anti-influenza agents conjugated with anti-inflammatory activity
WO2013163176A1 (en) 2012-04-23 2013-10-31 Allertein Therapeutics, Llc Nanoparticles for treatment of allergy
EP3492101A3 (de) 2012-05-10 2019-10-23 Massachusetts Institute Of Technology Mittel zur influenzaneutralisierung
PL2682146T3 (pl) * 2012-07-05 2017-04-28 Mt Derm Gmbh Przyrząd ręczny do tatuowania lub nanoszenia makijażu permanentnego oraz moduł igłowy z regulowaną głębokością wkłuwania
US20140037680A1 (en) 2012-08-06 2014-02-06 Glaxosmithkline Biologicals, S.A. Novel method
CA2879939A1 (en) 2012-08-06 2014-02-13 Glaxosmithkline Biologicals S.A. Novel method
AU2013203000B9 (en) 2012-08-10 2017-02-02 Lantheus Medical Imaging, Inc. Compositions, methods, and systems for the synthesis and use of imaging agents
WO2014028463A1 (en) 2012-08-14 2014-02-20 Allergan, Inc. Syringe for mixing and dispensing adipose tissue
AU2013306098A1 (en) 2012-08-18 2015-02-12 Academia Sinica Cell-permeable probes for identification and imaging of sialidases
JP5934367B2 (ja) * 2012-08-30 2016-06-15 テルモ株式会社 シリンジ用フランジ部材
WO2014052647A2 (en) 2012-09-26 2014-04-03 President And Fellows Of Harvard College Proline-locked stapled peptides and uses thereof
US20150225471A1 (en) 2012-10-01 2015-08-13 President And Fellows Of Harvard College Stabilized polypeptide insulin receptor modulators
HUE043853T2 (hu) 2012-10-12 2019-09-30 Broad Inst Inc GSK3 inhibitorok és eljárások azok alkalmazására
EP2909194A1 (de) 2012-10-18 2015-08-26 Dana-Farber Cancer Institute, Inc. Hemmer der cyclinabhängigen kinase 7 (cdk7)
US9758522B2 (en) 2012-10-19 2017-09-12 Dana-Farber Cancer Institute, Inc. Hydrophobically tagged small molecules as inducers of protein degradation
US10000483B2 (en) 2012-10-19 2018-06-19 Dana-Farber Cancer Institute, Inc. Bone marrow on X chromosome kinase (BMX) inhibitors and uses thereof
EP2914256B1 (de) 2012-11-01 2019-07-31 Aileron Therapeutics, Inc. Disubstituierte aminosäuren und verfahren zur herstellung und verwendung davon
EP2914296B2 (de) 2012-11-01 2021-09-29 Infinity Pharmaceuticals, Inc. Behandlung von krebs mit pi3-kinase-isoformmodulatoren
WO2014071247A1 (en) 2012-11-02 2014-05-08 Dana-Farber Cancer Institute, Inc. Pyrrol-1 -yl benzoic acid derivates useful as myc inhibitors
EP2922542A4 (de) 2012-11-21 2016-10-05 Topokine Therapeutics Inc Verfahren und zusammensetzungen zur lokalen körperfettvermehrung
CA2892529C (en) 2012-11-26 2023-04-25 Moderna Therapeutics, Inc. Terminally modified rna
JP6408478B2 (ja) 2012-11-26 2018-10-17 プレジデント アンド フェローズ オブ ハーバード カレッジ トリオキサカルシン、トリオキサカルシン−抗体複合体、およびその用途
JP6678455B2 (ja) 2012-12-21 2020-04-08 エピザイム，インコーポレイティド Ｐｒｍｔ５阻害剤およびその使用
EP2935241A1 (de) 2012-12-21 2015-10-28 Epizyme, Inc. Prmt5-inhibitor und verwendungen davon
US9745291B2 (en) 2012-12-21 2017-08-29 Epizyme, Inc. PRMT5 inhibitors containing a dihydro- or tetrahydroisoquinoline and uses thereof
US9908887B2 (en) 2012-12-21 2018-03-06 Epizyme, Inc. PRMT5 inhibitors and uses thereof
JP2016504050A (ja) 2013-01-17 2016-02-12 モデルナ セラピューティクス インコーポレイテッドＭｏｄｅｒｎａ Ｔｈｅｒａｐｅｕｔｉｃｓ，Ｉｎｃ． 細胞表現型の改変のためのシグナルセンサーポリヌクレオチド
US11576958B2 (en) 2013-02-07 2023-02-14 Children's Medical Center Corporation Protein antigens that provide protection against pneumococcal colonization and/or disease
CA2898633C (en) 2013-02-07 2021-07-13 Massachusetts Institute Of Technology Human adaptation of h5 influenza
US20160024181A1 (en) 2013-03-13 2016-01-28 Moderna Therapeutics, Inc. Long-lived polynucleotide molecules
CN110105434A (zh) 2013-03-13 2019-08-09 哈佛大学的校长及成员们 钉合且缝合的多肽及其用途
US20160024051A1 (en) 2013-03-15 2016-01-28 Infinity Pharmaceuticals, Inc. Salts and solid forms of isoquinolinones and composition comprising and methods of using the same
CN105188741A (zh) 2013-04-03 2015-12-23 阿勒丁医疗公司 新型纳米颗粒组合物
CN105246334A (zh) 2013-04-04 2016-01-13 哈佛大学的校长及成员们 大环内酯及其制备和使用方法
US9381253B2 (en) 2013-04-09 2016-07-05 Massachusetts Institute Of Technology Drug delivery polymer and uses thereof
US10301359B2 (en) 2013-04-30 2019-05-28 Massachusetts Institute Of Technology Human adaptation of H3 influenza
US9315472B2 (en) 2013-05-01 2016-04-19 Massachusetts Institute Of Technology 1,3,5-triazinane-2,4,6-trione derivatives and uses thereof
NO2753788T3 (de) 2013-05-10 2018-06-16
US20140350516A1 (en) 2013-05-23 2014-11-27 Allergan, Inc. Mechanical syringe accessory
US20140350518A1 (en) 2013-05-23 2014-11-27 Allergan, Inc. Syringe extrusion accessory
CA2914284A1 (en) 2013-05-30 2014-12-04 Infinity Pharmaceuticals, Inc. Treatment of cancers using pi3 kinase isoform modulators
WO2014197723A2 (en) 2013-06-05 2014-12-11 Massachusetts Institute Of Technology Human adaptation of h7 ha
GB2515041B (en) * 2013-06-11 2015-04-22 Cilag Gmbh Int Injection Device
GB2515039B (en) 2013-06-11 2015-05-27 Cilag Gmbh Int Injection Device
GB2517896B (en) 2013-06-11 2015-07-08 Cilag Gmbh Int Injection device
GB2515032A (en) * 2013-06-11 2014-12-17 Cilag Gmbh Int Guide for an injection device
AU2014278231B2 (en) 2013-06-11 2017-05-25 KALA BIO, Inc. Urea derivatives and uses thereof
GB2515038A (en) 2013-06-11 2014-12-17 Cilag Gmbh Int Injection device
WO2014201370A1 (en) 2013-06-14 2014-12-18 President And Fellows Of Harvard College Stabilized polypeptide insulin receptor modulators
US10086054B2 (en) 2013-06-26 2018-10-02 Academia Sinica RM2 antigens and use thereof
WO2014210564A1 (en) 2013-06-27 2014-12-31 Academia Sinica Glycan conjugates and use thereof
WO2015013635A2 (en) 2013-07-25 2015-01-29 Dana-Farber Cancer Institute, Inc. Inhibitors of transcription factors and uses thereof
SG11201600709TA (en) 2013-08-05 2016-02-26 Glaxosmithkline Biolog Sa Combination immunogenic compositions
US9688977B2 (en) 2013-08-05 2017-06-27 Greenlight Biosciences, Inc. Engineered phosphoglucose isomerase proteins with a protease cleavage site
US9782476B2 (en) 2013-09-06 2017-10-10 Academia Sinica Human iNKT cell activation using glycolipids with altered glycosyl groups
ES2900806T3 (es) 2013-10-04 2022-03-18 Infinity Pharmaceuticals Inc Compuestos heterocíclicos y usos de los mismos
WO2015051241A1 (en) 2013-10-04 2015-04-09 Infinity Pharmaceuticals, Inc. Heterocyclic compounds and uses thereof
US9982009B2 (en) 2013-10-15 2018-05-29 Massachusetts Institute Of Technology Methods for treating polycystic kidney disease and polycystic liver disease
WO2015057958A2 (en) 2013-10-16 2015-04-23 Massachusetts Institute Of Technology Enterobactin conjugates and uses thereof
EP3057956B1 (de) 2013-10-18 2021-05-05 Dana-Farber Cancer Institute, Inc. Polycyclische inhibitoren der cyclin-dependent-kinase 7 (cdk7)
AU2014337122B2 (en) 2013-10-18 2019-01-03 Dana-Farber Cancer Institute, Inc. Heteroaromatic compounds useful for the treatment of proliferative diseases
US20160244452A1 (en) 2013-10-21 2016-08-25 Infinity Pharmaceuticals, Inc. Heterocyclic compounds and uses thereof
AU2014342042B2 (en) 2013-11-01 2017-08-17 KALA BIO, Inc. Crystalline forms of therapeutic compounds and uses thereof
EA201891279A1 (ru) 2013-12-24 2019-01-31 Президент Энд Феллоус Оф Гарвард Колледж Аналоги кортистатина, их синтез и применения
US10150818B2 (en) 2014-01-16 2018-12-11 Academia Sinica Compositions and methods for treatment and detection of cancers
EP3094352B1 (de) 2014-01-16 2020-09-23 Academia Sinica Zusammensetzungen und verfahren zur behandlung und zum nachweis von krebs
JP2017504651A (ja) 2014-01-31 2017-02-09 ダナ−ファーバー キャンサー インスティテュート， インコーポレイテッド ジアゼパン誘導体の使用
MX2016011517A (es) 2014-03-07 2017-04-13 Univ Arizona Peptidos de crmp2 no narcoticos que seleccionan como diana canales de sodio para el dolor cronico.
DK3119397T3 (da) 2014-03-19 2022-03-28 Infinity Pharmaceuticals Inc Heterocykliske forbindelser til anvendelse i behandling af PI3K-gamma-medierede lidelser
WO2015148915A1 (en) 2014-03-27 2015-10-01 Academia Sinica Reactive labelling compounds and uses thereof
ES2868305T3 (es) 2014-03-28 2021-10-21 Univ Washington Through Its Center For Commercialization Vacunas contra el cáncer de mama y de ovario
US9862688B2 (en) 2014-04-23 2018-01-09 Dana-Farber Cancer Institute, Inc. Hydrophobically tagged janus kinase inhibitors and uses thereof
US10017477B2 (en) 2014-04-23 2018-07-10 Dana-Farber Cancer Institute, Inc. Janus kinase inhibitors and uses thereof
WO2015168079A1 (en) 2014-04-29 2015-11-05 Infinity Pharmaceuticals, Inc. Pyrimidine or pyridine derivatives useful as pi3k inhibitors
US10039816B2 (en) 2014-04-30 2018-08-07 Massachusetts Institute Of Technology Siderophore-based immunization against gram-negative bacteria
US10029048B2 (en) 2014-05-13 2018-07-24 Allergan, Inc. High force injection devices
JP6759109B2 (ja) 2014-05-21 2020-09-23 プレジデント アンド フェローズ オブ ハーバード カレッジ Ｒａｓ抑制性ペプチドおよびその使用
US10118969B2 (en) 2014-05-27 2018-11-06 Academia Sinica Compositions and methods relating to universal glycoforms for enhanced antibody efficacy
AU2015267045B2 (en) 2014-05-27 2021-02-25 Academia Sinica Anti-HER2 glycoantibodies and uses thereof
CA2950577A1 (en) 2014-05-27 2015-12-03 Academia Sinica Fucosidase from bacteroides and methods using the same
KR20220151036A (ko) 2014-05-27 2022-11-11 아카데미아 시니카 항-ｃｄ20 글리코항체 및 이의 용도
KR102494193B1 (ko) 2014-05-28 2023-01-31 아카데미아 시니카 항-ｔｎｆ-알파 글리코항체 및 이의 용도
CA2951430A1 (en) 2014-06-13 2015-12-17 Glaxosmithkline Biologicals Sa Immunogenic combinations
DK3157916T3 (en) 2014-06-19 2019-03-18 Ariad Pharma Inc HETEROARYL COMPOUNDS FOR CHINESE INHIBITION
WO2015200425A1 (en) 2014-06-27 2015-12-30 Topokine Therapeutics, Inc. Topical dosage regimen
US9840479B2 (en) 2014-07-02 2017-12-12 Massachusetts Institute Of Technology Polyamine-fatty acid derived lipidoids and uses thereof
JP6820830B2 (ja) 2014-07-18 2021-01-27 ユニヴァーシティ オブ ワシントン がんワクチン組成物およびその使用方法
WO2016025643A1 (en) 2014-08-12 2016-02-18 Massachusetts Institute Of Technology Brush-poly(glycoamidoamine)-lipids and uses thereof
EP3191500A4 (de) 2014-09-08 2018-04-11 Academia Sinica Aktivierung menschlicher inkt-zellen mithilfe von glykolipiden
JP2017533889A (ja) 2014-09-24 2017-11-16 エルロン・セラピューティクス・インコーポレイテッドＡｉｌｅｒｏｎ Ｔｈｅｒａｐｅｕｔｉｃｓ，Ｉｎｃ． ペプチド模倣大環状分子およびその使用
CN112972378A (zh) 2014-09-24 2021-06-18 艾瑞朗医疗公司 拟肽大环化合物及其制剂
US10226585B2 (en) 2014-10-01 2019-03-12 Allergan, Inc. Devices for injection and dosing
WO2016054491A1 (en) 2014-10-03 2016-04-07 Infinity Pharmaceuticals, Inc. Heterocyclic compounds and uses thereof
EP3760618A1 (de) 2014-10-21 2021-01-06 ARIAD Pharmaceuticals, Inc. Kristalline formen von 5-chlor-n4-[-2-(dimethylphosphoryl)phenyl]-n2-{2-methoxy-4-[4-(4-methylpiperazin-1-yl)piperidin-1-yl]pyrimidin-2,4-diamin
JP2017533238A (ja) 2014-10-28 2017-11-09 アンスティチュ ナショナル ドゥ ラ サンテ エ ドゥ ラ ルシェルシュ メディカル 抗原特異的寛容のための組成物及び方法
EP3041948B1 (de) 2014-11-10 2019-01-09 Modernatx, Inc. Alternative nukleinsäuremoleküle mit reduziertem uracilgehalt und verwendungen davon
US10253045B2 (en) 2014-11-26 2019-04-09 Kala Pharmaceuticals, Inc. Crystalline forms of a therapeutic compound and uses thereof
US11071643B2 (en) 2014-11-28 2021-07-27 Visionisti Oy Ocular therapeutics tool
US10174022B2 (en) 2014-12-10 2019-01-08 Kala Pharmaceuticals, Inc. 1-amino-triazolo(1,5-A)pyridine-substituted urea derivative and uses thereof
CN107205938A (zh) 2014-12-18 2017-09-26 温德加普医疗股份有限公司 用于溶解或增溶治疗剂的方法和组合物
KR102554779B1 (ko) 2014-12-23 2023-07-11 슬로안-케테링인스티튜트퍼캔서리서치 그라나티신 b의 다형체
CA2972239A1 (en) 2014-12-23 2016-06-30 Dana-Farber Cancer Institute, Inc. Inhibitors of cyclin-dependent kinase 7 (cdk7)
US10495645B2 (en) 2015-01-16 2019-12-03 Academia Sinica Cancer markers and methods of use thereof
US9975965B2 (en) 2015-01-16 2018-05-22 Academia Sinica Compositions and methods for treatment and detection of cancers
EP3248005B1 (de) 2015-01-24 2020-12-09 Academia Sinica Neuartige glycankonjugate und verfahren zur verwendung davon
JP2018507771A (ja) 2015-03-10 2018-03-22 アラーガン ファーマシューティカルズ ホールディングス （アイルランド） アンリミテッド カンパニー 多針注入器
EP3294318A4 (de) 2015-03-20 2019-04-03 Aileron Therapeutics, Inc. Peptidomimetische makrozyklen und verwendungen davon
JP6861166B2 (ja) 2015-03-27 2021-04-21 ダナ−ファーバー キャンサー インスティテュート， インコーポレイテッド サイクリン依存性キナーゼの阻害剤
CR20170485A (es) 2015-03-30 2018-02-05 Greenlight Biosciences Inc Producción de ácido ribonucleico libre de células
CN107708693A (zh) 2015-04-27 2018-02-16 佛罗里达大学研究基金会 代谢程序化的金属螯合剂及其用途
WO2016178591A2 (en) 2015-05-05 2016-11-10 Gene Predit, Sa Genetic markers and treatment of male obesity
AU2016276963C1 (en) 2015-06-12 2021-08-05 Dana-Farber Cancer Institute, Inc. Combination therapy of transcription inhibitors and kinase inhibitors
JP6800410B2 (ja) 2015-06-19 2020-12-16 マサチューセッツ インスティテュート オブ テクノロジー アルケニル置換２，５−ピペラジンジオン、および、対象または細胞に剤を送達するための組成物におけるそれらの使用
US10059741B2 (en) 2015-07-01 2018-08-28 Aileron Therapeutics, Inc. Peptidomimetic macrocycles
WO2017044858A2 (en) 2015-09-09 2017-03-16 Dana-Farber Cancer Institute, Inc. Inhibitors of cyclin-dependent kinases
US10023613B2 (en) 2015-09-10 2018-07-17 Aileron Therapeutics, Inc. Peptidomimetic macrocycles as modulators of MCL-1
RS63030B1 (sr) 2015-09-17 2022-04-29 Modernatx Inc Jedinjenja i kompozicije za intracelularno isporučivanje terapeutskih sredstava
EP3350333B1 (de) 2015-09-17 2021-10-27 ModernaTX, Inc. Polynukleotide mit stabilisierendem schwanzbereich
US9925170B2 (en) 2015-10-01 2018-03-27 Kythera Biopharmaceuticals, Inc. Methods of adipolysis and compositions useful therein
JP7114465B2 (ja) 2015-12-22 2022-08-08 モデルナティエックス インコーポレイテッド 薬剤の細胞内送達のための化合物および組成物
USD806246S1 (en) 2016-02-25 2017-12-26 Steven Schraga Lancet cover
WO2017156192A1 (en) 2016-03-08 2017-09-14 Academia Sinica Methods for modular synthesis of n-glycans and arrays thereof
WO2017161116A1 (en) 2016-03-17 2017-09-21 Infinity Pharmaceuticals, Inc. Isotopologues of isoquinolinone and quinazolinone compounds and uses thereof as pi3k kinase inhibitors
JP6910075B2 (ja) 2016-03-28 2021-07-28 イコル メディカル システムズ，インク． 治療薬の送達のための方法および装置
JP7011599B2 (ja) 2016-04-06 2022-02-10 グリーンライト バイオサイエンシーズ インコーポレーテッド リボ核酸の無細胞的生産
RU2725968C2 (ru) 2016-04-08 2020-07-07 Аллерган, Инк. Аспирационно-инъекционное устройство
CN106110442A (zh) * 2016-04-22 2016-11-16 杨海燕 一次性胰岛素深浅注射器
CN115746107A (zh) 2016-06-03 2023-03-07 圣诺菲·帕斯图尔公司 经改造的流感血凝素多肽的修饰
WO2017214337A1 (en) 2016-06-07 2017-12-14 Massachusetts Institute Of Technology Drug delivery polymers and uses thereof
WO2017214269A1 (en) 2016-06-08 2017-12-14 Infinity Pharmaceuticals, Inc. Heterocyclic compounds and uses thereof
EP3468537A1 (de) 2016-06-14 2019-04-17 Modernatx, Inc. Stabilisierte formulierungen von lipidnanopartikeln
US10898658B2 (en) 2016-07-06 2021-01-26 LynJohnston, LLC Compact injection device with telescoping components
CN109862908B (zh) 2016-08-05 2023-05-02 圣诺菲·帕斯图尔公司 多价肺炎球菌多糖-蛋白质缀合物组合物
CN109890415B (zh) 2016-08-05 2023-04-04 圣诺菲·帕斯图尔公司 多价肺炎球菌多糖-蛋白质缀合物组合物
CN109963868B (zh) 2016-08-22 2023-11-14 醣基生医股份有限公司 抗体、结合片段及使用方法
US11583504B2 (en) 2016-11-08 2023-02-21 Modernatx, Inc. Stabilized formulations of lipid nanoparticles
CN110198703A (zh) 2016-11-21 2019-09-03 艾里奥治疗公司 大试剂的透皮递送
WO2018106738A1 (en) 2016-12-05 2018-06-14 Massachusetts Institute Of Technology Brush-arm star polymers, conjugates and particles, and uses thereof
JP7332478B2 (ja) 2017-03-15 2023-08-23 モデルナティエックス インコーポレイテッド 脂質ナノ粒子製剤
SG11201907916TA (en) 2017-03-15 2019-09-27 Modernatx Inc Compounds and compositions for intracellular delivery of therapeutic agents
US11555031B2 (en) 2017-03-20 2023-01-17 The Broad Institute, Inc. Compounds and methods for regulating insulin secretion
USD867582S1 (en) 2017-03-24 2019-11-19 Allergan, Inc. Syringe device
EP3606528B1 (de) 2017-04-05 2023-10-18 The Broad Institute, Inc. Tricyclische verbindungen als inhibitoren der glycogensynthasekinase 3 (gsk3) und ihre verwendungen
EP3638678A1 (de) 2017-06-14 2020-04-22 Modernatx, Inc. Verbindungen und zusammensetzungen zur intrazellulären verabreichung von wirkstoffen
WO2019013790A1 (en) 2017-07-12 2019-01-17 Curza Global, Llc ANTIMICROBIAL COMPOUNDS AND USES THEREOF
WO2019013789A1 (en) 2017-07-12 2019-01-17 Curza Global, Llc ANTIMICROBIAL COMPOUNDS
EP3675817A1 (de) 2017-08-31 2020-07-08 Modernatx, Inc. Verfahren zur herstellung von lipidnanopartikeln
EP3695002A1 (de) 2017-10-11 2020-08-19 GreenLight Biosciences, Inc. Verfahren und zusammensetzungen zur herstellung von nukleosidtriphosphat und ribonukleinsäure
WO2019109079A1 (en) 2017-12-01 2019-06-06 North Carolina State University Fibrin particles and methods of making the same
AU2019206534A1 (en) 2018-01-10 2020-07-30 LynJohnston, LLC Compact injector systems and methods
MX2021002995A (es) 2018-09-13 2021-07-15 Eirion Therapeutics Inc Inhibidores del inhibidor 1 de activador de plasminogeno (pai-1) y usos de los mismos.
EP3849540A1 (de) 2018-09-13 2021-07-21 Eirion Therapeutics, Inc. Verwendung von inhibitoren des plasminogenaktivatorinhibitors 1 (pai-1)
WO2020061367A1 (en) 2018-09-19 2020-03-26 Modernatx, Inc. Compounds and compositions for intracellular delivery of therapeutic agents
JP2022501367A (ja) 2018-09-20 2022-01-06 モデルナティエックス インコーポレイテッドModernaTX, Inc. 脂質ナノ粒子の調製及びその投与方法
US20220031595A1 (en) 2018-12-03 2022-02-03 Eirion Therapeutics, Inc. Improved delivery of large agents
EP3911644A1 (de) 2019-01-16 2021-11-24 Curza Global LLC Antimikrobielle verbindungen und verfahren
CN113825748A (zh) 2019-01-16 2021-12-21 库扎环球有限责任公司 抗微生物化合物和方法
CN109674651B (zh) * 2019-01-23 2021-05-04 湖南中医药大学 一种用于中医针灸的进针器
AU2020214843A1 (en) 2019-01-31 2021-08-19 Modernatx, Inc. Methods of preparing lipid nanoparticles
WO2020168466A1 (en) 2019-02-19 2020-08-27 Stemirna Therapeutics Co., Ltd. Modified nucleoside and synthetic methods thereof
BR112021022619A2 (pt) 2019-05-14 2022-01-04 Eirion Therapeutics Inc Retardo de efeito de pico e/ou prolongamento de duração de resposta
AU2020323498A1 (en) 2019-07-31 2022-03-03 Sk Bioscience Co., Ltd. Multivalent pneumococcal polysaccharide-protein conjugate compositions and methods of using the same
JP2022543773A (ja) 2019-07-31 2022-10-14 モデルナティエックス インコーポレイテッド 免疫細胞へのｒｎａ干渉剤の送達のための組成物及び方法
AU2020384885A1 (en) 2019-11-13 2022-06-09 Curza Global, Llc Antimicrobial compounds and methods
MX2022009410A (es) 2020-01-31 2022-10-18 Modernatx Inc Metodos de preparacion de nanoparticulas lipidicas.
WO2021173965A1 (en) 2020-02-28 2021-09-02 Massachusetts Institute Of Technology Identification of variable influenza residues and uses thereof
WO2021231729A1 (en) 2020-05-13 2021-11-18 Sanofi Adjuvanted stabilized stem hemagglutinin nanoparticles and methods of using the same to induce broadly neutralizing antibodies against influenza
US20230174576A1 (en) 2020-10-30 2023-06-08 Xeno-Interface Inc. Beta-strand bridge peptide
WO2022092294A1 (ja) 2020-10-30 2022-05-05 学校法人慶應義塾 サルコペニア関連疾患等の新規治療および予防
AR124267A1 (es) 2020-12-09 2023-03-01 Genentech Inc Métodos de alto rendimiento para preparar nanopartículas lipídicas y sus usos
WO2022192176A1 (en) 2021-03-09 2022-09-15 Massachusetts Institute Of Technology Branched poly(-amino esters) for the delivery of nucleic acids
TW202313065A (zh) 2021-05-28 2023-04-01 美商季卡尼醫療公司 用於治療遺傳疾病之化合物
WO2023018817A1 (en) 2021-08-11 2023-02-16 Sanofi Pasteur Inc. Truncated influenza neuraminidase and methods of using the same
WO2023059857A1 (en) 2021-10-08 2023-04-13 Sanofi Pasteur Inc. Multivalent influenza vaccines
WO2023079113A1 (en) 2021-11-05 2023-05-11 Sanofi Hybrid multivalent influenza vaccines comprising hemagglutinin and neuraminidase and methods of using the same
WO2023081798A1 (en) 2021-11-05 2023-05-11 Sanofi Pasteur Inc. Multivalent influenza vaccines comprising recombinant hemagglutinin and neuraminidase and methods of using the same
TW202333654A (zh) 2021-12-16 2023-09-01 美商現代公司 用於製備脂質奈米顆粒之方法
WO2023129963A1 (en) 2021-12-30 2023-07-06 Curza Global, Llc Antimicrobial compounds and methods
WO2023144206A1 (en) 2022-01-27 2023-08-03 Sanofi Pasteur Modified vero cells and methods of using the same for virus production
WO2023177577A1 (en) 2022-03-14 2023-09-21 Sanofi Pasteur Inc. Machine-learning techniques in protein design for vaccine generation
WO2023193002A1 (en) 2022-04-01 2023-10-05 Modernatx, Inc. Cross mixers for lipid nanoparticle production, and methods of operating the same
WO2023235380A1 (en) 2022-06-01 2023-12-07 Zikani Therapeutics, Inc. Macrolides for treating genetic diseases
WO2023250513A1 (en) 2022-06-24 2023-12-28 Zikani Therapeutics, Inc. 13-membered macrolide compounds for treating diseases mediated by abnormal protein translation
WO2024026487A1 (en) 2022-07-29 2024-02-01 Modernatx, Inc. Lipid nanoparticle compositions comprising phospholipid derivatives and related uses
WO2024026482A1 (en) 2022-07-29 2024-02-01 Modernatx, Inc. Lipid nanoparticle compositions comprising surface lipid derivatives and related uses
WO2024026475A1 (en) 2022-07-29 2024-02-01 Modernatx, Inc. Compositions for delivery to hematopoietic stem and progenitor cells (hspcs) and related uses
WO2024049994A1 (en) 2022-09-01 2024-03-07 Zikani Therapeutics, Inc. Treatment of familial adenomatous polyopsis using a 13-membered macrolide
KR20240056970A (ko) * 2022-10-24 2024-05-02 이성호 피부미용용 니들 스탬프
WO2024091918A2 (en) 2022-10-25 2024-05-02 Modernatx, Inc. Methods of lipid nanoparticle production in cross-mixers

Family Cites Families (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2565081A (en) * 1948-09-15 1951-08-21 Emma C Maynes Device for operating hypodermic syringes
US2671448A (en) * 1951-02-19 1954-03-09 Georgiana W Harnisch Automatic hypodermic syringe
US2874694A (en) * 1957-06-24 1959-02-24 Omega Prec Medical Instr Co In Hypodermic syringes
US2959170A (en) * 1957-12-26 1960-11-08 Ernest S V Laub Hypodermic syringe
US3217712A (en) * 1963-01-22 1965-11-16 Otto Konigslow Mfg Company Ampoule applicator
US3612051A (en) * 1968-07-24 1971-10-12 Raul Olvera Arce Hypodermic syringe applicating device
US3605743A (en) * 1968-10-14 1971-09-20 Raul Olvera Arce Hypodermic syringe
US4194505A (en) * 1978-09-15 1980-03-25 Vac-O-Cast, Inc. Containerized hypodermic module
AU6056880A (en) * 1979-07-20 1981-02-13 Kling, L. Device for injection syringes
US4445510A (en) * 1982-09-13 1984-05-01 Rigby Ronald F Automatic injector for hypodermic syringes or the like and lancet holder for use in conjunction with an automatic injector
US4629454A (en) * 1985-03-29 1986-12-16 Grier Dale C Hypodermic syringe
US4601708A (en) * 1985-09-09 1986-07-22 Pavel Jordan Automatic injection for syringe needle, and assembly
DD250467A1 (de) * 1986-06-30 1987-10-14 Tech Hochschule C Schorlemmer Dosierinjektionseinrichtung
US4710179A (en) * 1986-10-27 1987-12-01 Habley Medical Technology Corporation Snap-on vernier syringe
DE3715340C2 (de) * 1987-05-08 1995-10-19 Haselmeier Wilhelm Fa Injektionsgerät
US4787891A (en) * 1987-07-13 1988-11-29 Paul Levin Syringe holder and applicator
US4858607A (en) * 1987-10-16 1989-08-22 Pavel Jordan & Associates Plastic device for injection and obtaining blood samples

Also Published As

Publication number Publication date
FR2638359A1 (fr) 1990-05-04
WO1990004988A1 (fr) 1990-05-17
JPH03503497A (ja) 1991-08-08
EP0371838A1 (de) 1990-06-06
EP0371838B1 (de) 1993-08-04
BR8907144A (pt) 1991-02-13
RU1836110C (ru) 1993-08-23
KR900701340A (ko) 1990-12-01
ATE92346T1 (de) 1993-08-15
AU4523089A (en) 1990-05-28
US5141496A (en) 1992-08-25
AU627795B2 (en) 1992-09-03
CA2002103A1 (fr) 1990-05-03

Similar Documents

Publication Publication Date Title
DE68908111D1 (de) Spritzenfuehrung mit einstellung der einstichtiefe der nadel in die haut.
BR8804162A (pt) Dispositivo de injecao em particular para ser utilizado apenas uma vez,para a injecao de um implante sob a pele e processo para a insercao de um implante em um corpo
ES2086291T3 (es) Dispositivo para la administracion de preparados solidos.
ES454409A1 (es) Un dispositivo para introducir un aguja en los tejidos de unpaciente junto con la aguja correspondiente.
ATE172882T1 (de) Sichere injektionsvorrichtung
SE8802502D0 (sv) Spruta
GB8519125D0 (en) Injector
DE3683089D1 (de) Wandtische.
JPS5628772A (en) Assembled article of catheter
SE8300795D0 (sv) Fixeringsanordning for katetrar och liknande
ATE83938T1 (de) Schutzschild fuer subkutane injektionsnadeln.
ES2009023A6 (es) Dispositivo para tornear interiormente.
DE3366671D1 (en) Injection apparatus for the treatment of wood
KR930011484B1 (ko) 자력을 이용한 인체 기맥(경혈)조절기
ES272596U (es) Inyector multiple para agujas de auriculo-medicina y acupuntura
DE3575674D1 (de) Vorrichtung fuer injektionsspritzen zur intramuskulaeren und subkutanen injektion.
ES232294U (es) Pendiente perfeccionado.
GB1062291A (en) Improvements relating to needle guns for skin puncture
ES260574U (es) Dispositivo de puncion para la toma de muestras sanguineas
ES258395A1 (es) Perfeccionamientos introducidos en las figuras animadas
UA9380A1 (uk) Прилад для біопсіі м'яких ткаhиh
SE8902061D0 (sv) Kateter med invaendigt utbytbar yta
ES275468U (es) Inyector multiple perfeccionado para agujas de auriculo-medicina y acupuntura
IT1225960B (it) Dispositivo di inserzione di prodotti a forma ogivale in un corpo umano o animale
ES1007331U (es) Cabezal para tratamientos por mesoterapia.

Legal Events

Date Code Title Description
8332 No legal effect for de