DE602005025855D1 - Makrocyclische peptide mit wirkung gegen das hepatitis-c-virus - Google Patents

Makrocyclische peptide mit wirkung gegen das hepatitis-c-virus

Info

Publication number
DE602005025855D1
DE602005025855D1 DE602005025855T DE602005025855T DE602005025855D1 DE 602005025855 D1 DE602005025855 D1 DE 602005025855D1 DE 602005025855 T DE602005025855 T DE 602005025855T DE 602005025855 T DE602005025855 T DE 602005025855T DE 602005025855 D1 DE602005025855 D1 DE 602005025855D1
Authority
DE
Germany
Prior art keywords
hepatitis
virus
effect
macrocyclic peptides
macrocyclic
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE602005025855T
Other languages
German (de)
English (en)
Inventor
Montse Llinas-Brunet
Murray Bailey
Punit K Bhardwaj
Francois Bilodeau
Pasquale Forgione
Elise Ghiro
Nathalie Goudreau
Teddy Halmos
Jean Rancourt
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Boehringer Ingelheim Pharma GmbH and Co KG
Boehringer Ingelheim Pharmaceuticals Inc
Original Assignee
Boehringer Ingelheim Pharma GmbH and Co KG
Boehringer Ingelheim Pharmaceuticals Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Boehringer Ingelheim Pharma GmbH and Co KG, Boehringer Ingelheim Pharmaceuticals Inc filed Critical Boehringer Ingelheim Pharma GmbH and Co KG
Publication of DE602005025855D1 publication Critical patent/DE602005025855D1/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/08—Tripeptides
    • C07K5/0802—Tripeptides with the first amino acid being neutral
    • C07K5/0804—Tripeptides with the first amino acid being neutral and aliphatic
    • C07K5/0808—Tripeptides with the first amino acid being neutral and aliphatic the side chain containing 2 to 4 carbon atoms, e.g. Val, Ile, Leu
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/20—Antivirals for DNA viruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/08—Tripeptides
    • C07K5/0802—Tripeptides with the first amino acid being neutral
    • C07K5/0812—Tripeptides with the first amino acid being neutral and aromatic or cycloaliphatic
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/08—Tripeptides
    • C07K5/0827—Tripeptides containing heteroatoms different from O, S, or N
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Virology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
DE602005025855T 2004-01-21 2005-01-18 Makrocyclische peptide mit wirkung gegen das hepatitis-c-virus Expired - Lifetime DE602005025855D1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US53786304P 2004-01-21 2004-01-21
PCT/CA2005/000055 WO2005070955A1 (en) 2004-01-21 2005-01-18 Macrocyclic peptides active against the hepatitis c virus

Publications (1)

Publication Number Publication Date
DE602005025855D1 true DE602005025855D1 (de) 2011-02-24

Family

ID=34807139

Family Applications (1)

Application Number Title Priority Date Filing Date
DE602005025855T Expired - Lifetime DE602005025855D1 (de) 2004-01-21 2005-01-18 Makrocyclische peptide mit wirkung gegen das hepatitis-c-virus

Country Status (12)

Country Link
US (2) US7749961B2 (https=)
EP (1) EP1730167B1 (https=)
JP (1) JP4682155B2 (https=)
AR (1) AR047444A1 (https=)
AT (1) ATE495185T1 (https=)
CA (1) CA2549851C (https=)
DE (1) DE602005025855D1 (https=)
ES (1) ES2358333T3 (https=)
PE (1) PE20050764A1 (https=)
TW (1) TW200528094A (https=)
UY (1) UY28722A1 (https=)
WO (1) WO2005070955A1 (https=)

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WO2005070955A1 (en) 2005-08-04
UY28722A1 (es) 2005-08-31
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JP2007534662A (ja) 2007-11-29
CA2549851C (en) 2012-09-11
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US20090264346A1 (en) 2009-10-22
AR047444A1 (es) 2006-01-18
ES2358333T3 (es) 2011-05-09
PE20050764A1 (es) 2005-11-24
US20050192212A1 (en) 2005-09-01
US7749961B2 (en) 2010-07-06
TW200528094A (en) 2005-09-01

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