DE602005010074D1 - Pharmazeutische zusammensetzungen mit verbesserter leistung enthaltend ein hpmca polymer - Google Patents
Pharmazeutische zusammensetzungen mit verbesserter leistung enthaltend ein hpmca polymerInfo
- Publication number
- DE602005010074D1 DE602005010074D1 DE602005010074T DE602005010074T DE602005010074D1 DE 602005010074 D1 DE602005010074 D1 DE 602005010074D1 DE 602005010074 T DE602005010074 T DE 602005010074T DE 602005010074 T DE602005010074 T DE 602005010074T DE 602005010074 D1 DE602005010074 D1 DE 602005010074D1
- Authority
- DE
- Germany
- Prior art keywords
- pharmaceutical compositions
- improved performance
- polymers
- hpmca
- performance containing
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08B—POLYSACCHARIDES; DERIVATIVES THEREOF
- C08B13/00—Preparation of cellulose ether-esters
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/141—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers
- A61K9/146—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers with organic macromolecular compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1605—Excipients; Inactive ingredients
- A61K9/1629—Organic macromolecular compounds
- A61K9/1652—Polysaccharides, e.g. alginate, cellulose derivatives; Cyclodextrin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2022—Organic macromolecular compounds
- A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
- A61K9/2054—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/06—Antihyperlipidemics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08B—POLYSACCHARIDES; DERIVATIVES THEREOF
- C08B11/00—Preparation of cellulose ethers
- C08B11/02—Alkyl or cycloalkyl ethers
- C08B11/04—Alkyl or cycloalkyl ethers with substituted hydrocarbon radicals
- C08B11/08—Alkyl or cycloalkyl ethers with substituted hydrocarbon radicals with hydroxylated hydrocarbon radicals; Esters, ethers, or acetals thereof
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08L—COMPOSITIONS OF MACROMOLECULAR COMPOUNDS
- C08L1/00—Compositions of cellulose, modified cellulose or cellulose derivatives
- C08L1/08—Cellulose derivatives
- C08L1/26—Cellulose ethers
- C08L1/28—Alkyl ethers
- C08L1/284—Alkyl ethers with hydroxylated hydrocarbon radicals
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08L—COMPOSITIONS OF MACROMOLECULAR COMPOUNDS
- C08L1/00—Compositions of cellulose, modified cellulose or cellulose derivatives
- C08L1/08—Cellulose derivatives
- C08L1/32—Cellulose ether-esters
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Life Sciences & Earth Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Polymers & Plastics (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Epidemiology (AREA)
- Biochemistry (AREA)
- Materials Engineering (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Psychiatry (AREA)
- Obesity (AREA)
- Diabetes (AREA)
- Hematology (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US57554104P | 2004-05-28 | 2004-05-28 | |
US58654904P | 2004-07-09 | 2004-07-09 | |
PCT/IB2005/001580 WO2005115330A2 (en) | 2004-05-28 | 2005-05-18 | Pharmaceutical compositions with enhanced performance |
Publications (1)
Publication Number | Publication Date |
---|---|
DE602005010074D1 true DE602005010074D1 (de) | 2008-11-13 |
Family
ID=35451370
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE602005010074T Expired - Fee Related DE602005010074D1 (de) | 2004-05-28 | 2005-05-18 | Pharmazeutische zusammensetzungen mit verbesserter leistung enthaltend ein hpmca polymer |
Country Status (8)
Country | Link |
---|---|
US (2) | US8207232B2 (de) |
EP (1) | EP1753402B1 (de) |
JP (1) | JP2008501009A (de) |
AT (1) | ATE409462T1 (de) |
CA (1) | CA2568007A1 (de) |
DE (1) | DE602005010074D1 (de) |
MX (1) | MXPA06013891A (de) |
WO (1) | WO2005115330A2 (de) |
Families Citing this family (92)
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DE60233874D1 (de) * | 2001-06-22 | 2009-11-12 | Pfizer Prod Inc | Pharmazeutische zusammensetzungen enthaltend dispersionen aus arzneistoffen und neutralen polymeren |
US8617604B2 (en) | 2005-02-03 | 2013-12-31 | Bend Research, Inc. | Pharmaceutical compositions with enhanced performance |
CA2686756A1 (en) * | 2007-05-11 | 2008-11-20 | F. Hoffmann-La Roche Ag | Pharmaceutical compositions for poorly soluble drugs |
WO2009125415A1 (en) * | 2008-04-07 | 2009-10-15 | Hetero Research Foundation | Amorphous form of sildenafil citrate |
US8685458B2 (en) | 2009-03-05 | 2014-04-01 | Bend Research, Inc. | Pharmaceutical compositions of dextran polymer derivatives |
ES2873502T3 (es) | 2009-03-27 | 2021-11-03 | Bend Res Inc | Proceso de secado por pulverización |
KR101682466B1 (ko) * | 2010-02-01 | 2016-12-05 | 롯데정밀화학 주식회사 | 아세틸화 셀룰로오스 에테르 및 이를 포함하는 물품 |
US20130108701A1 (en) | 2010-05-25 | 2013-05-02 | Krishna Murthy Bhavanasi | Solid Dosage Forms of Antipsychotics |
CN103153343B (zh) * | 2010-06-14 | 2015-02-11 | 陶氏环球技术有限责任公司 | 具有提高的醋酸酯和琥珀酸酯取代的醋酸羟丙基甲基纤维素琥珀酸酯 |
PT2611530T (pt) | 2010-09-03 | 2019-05-09 | Bend Res Inc | Aparelho de secagem por pulverização e métodos de utilização do mesmo |
PT2611529T (pt) | 2010-09-03 | 2019-05-09 | Bend Res Inc | Método de secagem por pulverização |
WO2012040502A1 (en) | 2010-09-24 | 2012-03-29 | Bend Research, Inc. | High-temperature spray drying process and apparatus |
KR101088845B1 (ko) * | 2011-01-21 | 2011-12-06 | 원광대학교산학협력단 | 황금 추출물의 속효성 고체 분산체, 이를 함유한 경구용 제제 및 이들의 제조방법 |
MX2013010306A (es) | 2011-03-08 | 2013-12-09 | Zalicus Pharmaceuticals Ltd | Formulaciones de dispersion solida y metodos de uso de las mismas. |
US8409560B2 (en) | 2011-03-08 | 2013-04-02 | Zalicus Pharmaceuticals Ltd. | Solid dispersion formulations and methods of use thereof |
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JP6235584B2 (ja) | 2012-07-17 | 2017-11-22 | ダウ グローバル テクノロジーズ エルエルシー | 高置換ヒドロキシアルキルメチルセルロースを含む固体分散体 |
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CN102807625A (zh) * | 2012-08-23 | 2012-12-05 | 浙江中维药业有限公司 | 一种醋酸羟丙甲纤维素琥珀酸酯的制备方法 |
US10730957B2 (en) | 2012-08-24 | 2020-08-04 | Dow Global Technologies Llc | Process of preparing an esterified cellulose ether in the presence of an alkali metal carboxylate and an aliphatic carboxylic acid |
BR112015002056A2 (pt) | 2012-08-24 | 2017-07-04 | Dow Global Technologies Llc | éter de celulose esterificado, composição, dispersão sólida, processo para produzir a dispersão sólida, forma de dosagem e invólucro de cápsula |
KR102138546B1 (ko) * | 2012-08-24 | 2020-07-28 | 다우 글로벌 테크놀로지스 엘엘씨 | 부분적으로 가교결합된 에스테르화된 셀룰로즈 에테르 |
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BR112015000073A2 (pt) | 2012-08-24 | 2017-06-27 | Dow Global Technologies Llc | processo para preparar dois ou mais ésteres de um éter de celulose e processo para preparar um éter de celulose esterificado |
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EP2956121B1 (de) | 2013-02-12 | 2018-05-30 | Bend Research, Inc. | Feste dispersionen mit geringer wasserlöslichkeit |
BR112015021179B1 (pt) | 2013-03-01 | 2021-11-30 | Hercules Incorporated | Polímero para melhor desempenho de fármaco e melhor processabilidade, composição compreendendo um fármaco e um polímero e método para a produção de acetato succinato de hidroxipropilmetilcelulose |
CN105025887B (zh) * | 2013-03-07 | 2017-07-28 | 陶氏环球技术有限责任公司 | 新颖极低粘度酯化纤维素醚 |
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2005
- 2005-05-18 DE DE602005010074T patent/DE602005010074D1/de not_active Expired - Fee Related
- 2005-05-18 CA CA002568007A patent/CA2568007A1/en not_active Abandoned
- 2005-05-18 WO PCT/IB2005/001580 patent/WO2005115330A2/en active IP Right Grant
- 2005-05-18 JP JP2007514203A patent/JP2008501009A/ja active Pending
- 2005-05-18 AT AT05742034T patent/ATE409462T1/de not_active IP Right Cessation
- 2005-05-18 EP EP05742034A patent/EP1753402B1/de not_active Not-in-force
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2012
- 2012-06-26 US US13/533,637 patent/US8940800B2/en active Active
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CA2568007A1 (en) | 2005-12-08 |
WO2005115330A2 (en) | 2005-12-08 |
EP1753402B1 (de) | 2008-10-01 |
JP2008501009A (ja) | 2008-01-17 |
MXPA06013891A (es) | 2007-01-26 |
EP1753402A2 (de) | 2007-02-21 |
US20080262107A1 (en) | 2008-10-23 |
US8207232B2 (en) | 2012-06-26 |
US20120264833A1 (en) | 2012-10-18 |
WO2005115330A3 (en) | 2006-07-06 |
US8940800B2 (en) | 2015-01-27 |
ATE409462T1 (de) | 2008-10-15 |
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