BRPI0717369A2 - Composto, medicamento, composição farmacêutica que o contém e uso do composto. - Google Patents
Composto, medicamento, composição farmacêutica que o contém e uso do composto.Info
- Publication number
- BRPI0717369A2 BRPI0717369A2 BRPI0717369-5A2A BRPI0717369A BRPI0717369A2 BR PI0717369 A2 BRPI0717369 A2 BR PI0717369A2 BR PI0717369 A BRPI0717369 A BR PI0717369A BR PI0717369 A2 BRPI0717369 A2 BR PI0717369A2
- Authority
- BR
- Brazil
- Prior art keywords
- compound
- pharmaceutical composition
- composition containing
- medicinal product
- medicinal
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
- C07D409/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/506—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim not condensed and containing further heterocyclic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/16—Central respiratory analeptics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/02—Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/04—Antihaemorrhagics; Procoagulants; Haemostatic agents; Antifibrinolytic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/06—Antianaemics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/08—Vasodilators for multiple indications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/14—Vasoprotectives; Antihaemorrhoidals; Drugs for varicose therapy; Capillary stabilisers
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
- C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
- C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
- C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
- C07D239/32—One oxygen, sulfur or nitrogen atom
- C07D239/34—One oxygen atom
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| IB2006053929 | 2006-10-25 | ||
| PCT/IB2007/054325 WO2008050301A2 (en) | 2006-10-25 | 2007-10-24 | 2- phenyl- 6-aminocarbonyl- pyrimidine derivatives and their use as p2y12 receptor antagonists |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| BRPI0717369A2 true BRPI0717369A2 (pt) | 2014-10-07 |
Family
ID=39324985
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BRPI0717369-5A2A BRPI0717369A2 (pt) | 2006-10-25 | 2007-10-24 | Composto, medicamento, composição farmacêutica que o contém e uso do composto. |
Country Status (22)
| Country | Link |
|---|---|
| US (1) | US8044055B2 (pt) |
| EP (1) | EP2079711B1 (pt) |
| JP (1) | JP5144670B2 (pt) |
| KR (1) | KR101434697B1 (pt) |
| CN (1) | CN101528715B (pt) |
| AR (1) | AR063518A1 (pt) |
| AT (1) | ATE454377T1 (pt) |
| AU (1) | AU2007310435A1 (pt) |
| BR (1) | BRPI0717369A2 (pt) |
| CA (1) | CA2664347C (pt) |
| CL (1) | CL2007003038A1 (pt) |
| DE (1) | DE602007004245D1 (pt) |
| ES (1) | ES2339408T3 (pt) |
| IL (1) | IL198334A0 (pt) |
| MA (1) | MA30903B1 (pt) |
| MX (1) | MX2009004186A (pt) |
| NO (1) | NO20091985L (pt) |
| PL (1) | PL2079711T3 (pt) |
| RU (1) | RU2009119421A (pt) |
| TW (1) | TW200829247A (pt) |
| WO (1) | WO2008050301A2 (pt) |
| ZA (1) | ZA200903574B (pt) |
Families Citing this family (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| TW200640877A (en) | 2005-04-28 | 2006-12-01 | Actelion Pharmaceuticals Ltd | Pyrimidine derivatives |
| AR063258A1 (es) | 2006-10-13 | 2009-01-14 | Actelion Pharmaceuticals Ltd | Derivados de 2-aminocarbonil-piridina, una composicion farmaceutica que los contiene y su uso en la preparacion de un medicamento para el tratamiento de trastornos vasculares oclusivos. |
| MY153749A (en) * | 2007-11-29 | 2015-03-13 | Actelion Pharmaceuticals Ltd | Phosphonic acid derivates and their use as p2y12 receptor antagonists |
| AR071653A1 (es) | 2008-04-11 | 2010-07-07 | Actelion Pharmaceuticals Ltd | Derivados 2-fenil-4-ciclopropil-pirimidina |
| AR071652A1 (es) | 2008-04-11 | 2010-07-07 | Actelion Pharmaceuticals Ltd | Derivados 2- fenil-piridina substituidos |
| JP5536873B2 (ja) | 2009-04-08 | 2014-07-02 | アクテリオン ファーマシューティカルズ リミテッド | ６−（３−アザ−ビシクロ［３．１．０］ヘクス−３−イル）−２−フェニル−ピリミジン（６−（３−ａｚａ−ｂｉｃｙｃｌｏ［３．１．０］ｈｅｘ−３−ｙｌ）−２−ｐｈｅｎｙｌ−ｐｙｒｉｍｉｄｉｎｅｓ） |
| JP5536876B2 (ja) | 2009-04-22 | 2014-07-02 | アクテリオン ファーマシューティカルズ リミテッド | チアゾール誘導体及びｐ２ｙ１２受容体拮抗剤としてのそれらの使用 |
| EP2750676B1 (en) | 2011-08-30 | 2018-01-10 | University of Utah Research Foundation | Methods and compositions for treating nephrogenic diabetes insipidus |
| CN102992968B (zh) * | 2012-08-15 | 2014-07-16 | 河北工业大学 | 2,3-二甲氧基-1-丙醇及其制备方法 |
| PL3515924T3 (pl) | 2016-09-22 | 2022-04-11 | Idorsia Pharmaceuticals Ltd | Krystaliczne postacie |
| MX2019009559A (es) | 2017-03-15 | 2019-10-15 | Idorsia Pharmaceuticals Ltd | Administracion subcutanea de un antagonista del receptor p2y12. |
Family Cites Families (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS5373586A (en) | 1976-12-09 | 1978-06-30 | Mitsubishi Chem Ind Ltd | New penicillin derivatives |
| JPS61227572A (ja) * | 1985-04-02 | 1986-10-09 | Ishihara Sangyo Kaisha Ltd | Ｎ−ベンゾイル−ｎ′−ピリミジニルオキシフエニルウレア系化合物及びそれらを含有する抗癌剤 |
| CA2375920A1 (en) * | 1999-06-14 | 2000-12-21 | Eli Lilly And Company | Compounds |
| US6861424B2 (en) | 2001-06-06 | 2005-03-01 | Schering Aktiengesellschaft | Platelet adenosine diphosphate receptor antagonists |
| CN1181062C (zh) * | 2001-12-28 | 2004-12-22 | 陈依军 | 2－苯氧基嘧啶衍生物及其治疗用途 |
| OA12970A (en) * | 2002-12-11 | 2006-10-13 | Schering Ag | 2-aminocarbonyl-quinoline compounds as platelet adenosine diphosphate receptor antagonists. |
| TW200640877A (en) * | 2005-04-28 | 2006-12-01 | Actelion Pharmaceuticals Ltd | Pyrimidine derivatives |
| AR063258A1 (es) | 2006-10-13 | 2009-01-14 | Actelion Pharmaceuticals Ltd | Derivados de 2-aminocarbonil-piridina, una composicion farmaceutica que los contiene y su uso en la preparacion de un medicamento para el tratamiento de trastornos vasculares oclusivos. |
| MY153749A (en) | 2007-11-29 | 2015-03-13 | Actelion Pharmaceuticals Ltd | Phosphonic acid derivates and their use as p2y12 receptor antagonists |
| AR071652A1 (es) | 2008-04-11 | 2010-07-07 | Actelion Pharmaceuticals Ltd | Derivados 2- fenil-piridina substituidos |
| AR071653A1 (es) | 2008-04-11 | 2010-07-07 | Actelion Pharmaceuticals Ltd | Derivados 2-fenil-4-ciclopropil-pirimidina |
| JP5536873B2 (ja) | 2009-04-08 | 2014-07-02 | アクテリオン ファーマシューティカルズ リミテッド | ６−（３−アザ−ビシクロ［３．１．０］ヘクス−３−イル）−２−フェニル−ピリミジン（６−（３−ａｚａ−ｂｉｃｙｃｌｏ［３．１．０］ｈｅｘ−３−ｙｌ）−２−ｐｈｅｎｙｌ−ｐｙｒｉｍｉｄｉｎｅｓ） |
| JP5536876B2 (ja) | 2009-04-22 | 2014-07-02 | アクテリオン ファーマシューティカルズ リミテッド | チアゾール誘導体及びｐ２ｙ１２受容体拮抗剤としてのそれらの使用 |
-
2007
- 2007-10-23 CL CL200703038A patent/CL2007003038A1/es unknown
- 2007-10-23 AR ARP070104678A patent/AR063518A1/es unknown
- 2007-10-24 KR KR1020097009600A patent/KR101434697B1/ko active IP Right Grant
- 2007-10-24 TW TW096139907A patent/TW200829247A/zh unknown
- 2007-10-24 MX MX2009004186A patent/MX2009004186A/es active IP Right Grant
- 2007-10-24 DE DE602007004245T patent/DE602007004245D1/de active Active
- 2007-10-24 AT AT07826850T patent/ATE454377T1/de active
- 2007-10-24 RU RU2009119421/04A patent/RU2009119421A/ru not_active Application Discontinuation
- 2007-10-24 PL PL07826850T patent/PL2079711T3/pl unknown
- 2007-10-24 ES ES07826850T patent/ES2339408T3/es active Active
- 2007-10-24 CN CN2007800399452A patent/CN101528715B/zh active Active
- 2007-10-24 AU AU2007310435A patent/AU2007310435A1/en not_active Abandoned
- 2007-10-24 EP EP07826850A patent/EP2079711B1/en active Active
- 2007-10-24 WO PCT/IB2007/054325 patent/WO2008050301A2/en active Application Filing
- 2007-10-24 US US12/447,039 patent/US8044055B2/en active Active
- 2007-10-24 JP JP2009534029A patent/JP5144670B2/ja active Active
- 2007-10-24 BR BRPI0717369-5A2A patent/BRPI0717369A2/pt not_active IP Right Cessation
- 2007-10-24 CA CA2664347A patent/CA2664347C/en active Active
-
2009
- 2009-04-23 IL IL198334A patent/IL198334A0/en unknown
- 2009-05-15 MA MA31890A patent/MA30903B1/fr unknown
- 2009-05-22 ZA ZA200903574A patent/ZA200903574B/xx unknown
- 2009-05-22 NO NO20091985A patent/NO20091985L/no not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| CA2664347A1 (en) | 2008-05-02 |
| ZA200903574B (en) | 2010-08-25 |
| MA30903B1 (fr) | 2009-11-02 |
| AU2007310435A1 (en) | 2008-05-02 |
| MX2009004186A (es) | 2009-05-11 |
| US8044055B2 (en) | 2011-10-25 |
| CL2007003038A1 (es) | 2008-06-06 |
| CN101528715B (zh) | 2011-08-24 |
| CA2664347C (en) | 2014-10-21 |
| ATE454377T1 (de) | 2010-01-15 |
| NO20091985L (no) | 2009-05-22 |
| JP2010507646A (ja) | 2010-03-11 |
| WO2008050301A3 (en) | 2008-10-09 |
| CN101528715A (zh) | 2009-09-09 |
| IL198334A0 (en) | 2010-02-17 |
| EP2079711B1 (en) | 2010-01-06 |
| JP5144670B2 (ja) | 2013-02-13 |
| AR063518A1 (es) | 2009-01-28 |
| WO2008050301A2 (en) | 2008-05-02 |
| US20090291962A1 (en) | 2009-11-26 |
| TW200829247A (en) | 2008-07-16 |
| KR101434697B1 (ko) | 2014-08-27 |
| EP2079711A2 (en) | 2009-07-22 |
| PL2079711T3 (pl) | 2010-06-30 |
| RU2009119421A (ru) | 2011-04-27 |
| KR20090068278A (ko) | 2009-06-25 |
| ES2339408T3 (es) | 2010-05-19 |
| DE602007004245D1 (de) | 2010-02-25 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| B08F | Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette] |
Free format text: REFERENTE AS 5A, 6A, 7A E 8A ANUIDADES. |
|
| B08K | Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette] |
Free format text: EM VIRTUDE DO ARQUIVAMENTO PUBLICADO NA RPI 2343 DE 01-12-2015 E CONSIDERANDO AUSENCIA DE MANIFESTACAO DENTRO DOS PRAZOS LEGAIS, INFORMO QUE CABE SER MANTIDO O ARQUIVAMENTO DO PEDIDO DE PATENTE, CONFORME O DISPOSTO NO ARTIGO 12, DA RESOLUCAO 113/2013. |