DE60026357D1 - An- und abschwellende polymermischungen - Google Patents

An- und abschwellende polymermischungen

Info

Publication number
DE60026357D1
DE60026357D1 DE60026357T DE60026357T DE60026357D1 DE 60026357 D1 DE60026357 D1 DE 60026357D1 DE 60026357 T DE60026357 T DE 60026357T DE 60026357 T DE60026357 T DE 60026357T DE 60026357 D1 DE60026357 D1 DE 60026357D1
Authority
DE
Germany
Prior art keywords
polymer
environment
blend
polymer blend
aqueous
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE60026357T
Other languages
English (en)
Other versions
DE60026357T2 (de
Inventor
M Zentner
Jong-Seok Bark
Feng Liu
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
BTG International Inc
Original Assignee
MacroMed Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US09/710,403 external-priority patent/US6537584B1/en
Application filed by MacroMed Inc filed Critical MacroMed Inc
Publication of DE60026357D1 publication Critical patent/DE60026357D1/de
Application granted granted Critical
Publication of DE60026357T2 publication Critical patent/DE60026357T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08L—COMPOSITIONS OF MACROMOLECULAR COMPOUNDS
    • C08L1/00—Compositions of cellulose, modified cellulose or cellulose derivatives
    • C08L1/08—Cellulose derivatives
    • C08L1/10—Esters of organic acids, i.e. acylates
    • C08L1/12—Cellulose acetate
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/2031—Organic macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, polyethylene oxide, poloxamers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08J—WORKING-UP; GENERAL PROCESSES OF COMPOUNDING; AFTER-TREATMENT NOT COVERED BY SUBCLASSES C08B, C08C, C08F, C08G or C08H
    • C08J3/00—Processes of treating or compounding macromolecular substances
    • C08J3/005—Processes for mixing polymers
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08L—COMPOSITIONS OF MACROMOLECULAR COMPOUNDS
    • C08L5/00—Compositions of polysaccharides or of their derivatives not provided for in groups C08L1/00 or C08L3/00
    • C08L5/02—Dextran; Derivatives thereof
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08L—COMPOSITIONS OF MACROMOLECULAR COMPOUNDS
    • C08L5/00—Compositions of polysaccharides or of their derivatives not provided for in groups C08L1/00 or C08L3/00
    • C08L5/08—Chitin; Chondroitin sulfate; Hyaluronic acid; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/2027—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
    • A61K9/2054—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Polymers & Plastics (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Epidemiology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Preparation (AREA)
  • Compositions Of Macromolecular Compounds (AREA)
  • Manufacture Of Porous Articles, And Recovery And Treatment Of Waste Products (AREA)
  • Separation Using Semi-Permeable Membranes (AREA)
  • Immobilizing And Processing Of Enzymes And Microorganisms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
DE60026357T 1999-11-12 2000-11-10 An- und abschwellende polymermischungen Expired - Lifetime DE60026357T2 (de)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US43888499A 1999-11-12 1999-11-12
US438884 1999-11-12
US710403 2000-11-09
US09/710,403 US6537584B1 (en) 1999-11-12 2000-11-09 Polymer blends that swell in an acidic environment and deswell in a basic environment
PCT/US2000/030908 WO2001034677A1 (en) 1999-11-12 2000-11-10 Swelling and deswelling polymer blends

Publications (2)

Publication Number Publication Date
DE60026357D1 true DE60026357D1 (de) 2006-04-27
DE60026357T2 DE60026357T2 (de) 2006-10-19

Family

ID=27031834

Family Applications (1)

Application Number Title Priority Date Filing Date
DE60026357T Expired - Lifetime DE60026357T2 (de) 1999-11-12 2000-11-10 An- und abschwellende polymermischungen

Country Status (12)

Country Link
US (2) US7182957B2 (de)
EP (1) EP1240230B1 (de)
CN (1) CN1181816C (de)
AT (1) ATE318846T1 (de)
AU (1) AU775527B2 (de)
BR (1) BR0015521B1 (de)
CA (1) CA2389251C (de)
DE (1) DE60026357T2 (de)
ES (1) ES2259618T3 (de)
HK (1) HK1052713B (de)
MX (1) MXPA02004583A (de)
WO (1) WO2001034677A1 (de)

Families Citing this family (34)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2259618T3 (es) * 1999-11-12 2006-10-16 Macromed, Inc. Mezclas de polimeros hinchables y deshinchables.
JP2002044663A (ja) * 2000-07-24 2002-02-08 Canon Inc 画像符号化装置及び方法、画像表示装置及び方法、画像処理システム並びに撮像装置
US6696618B2 (en) 2001-12-12 2004-02-24 Kimberly-Clark Worldwide, Inc. Absorbent composites exhibiting swelling/deswelling properties
GB0130518D0 (en) * 2001-12-21 2002-02-06 Univ Gent Pulsed bio-agent delivery systems based on degradable polymer solutions or hydrogels
CN100413919C (zh) * 2002-12-13 2008-08-27 上海爱普食品工业有限公司 复合型可食性壳聚糖膜的制备方法
US20050112151A1 (en) * 2003-11-20 2005-05-26 Horng Liou L. Skin adherent hydrogels
GB0329907D0 (en) * 2003-12-23 2004-01-28 Innomed Ltd Compositions
WO2006130117A1 (en) * 2005-06-03 2006-12-07 National University Of Singapore Novel polymer blends and applications for their use in hollow polymer fibers
WO2007014447A1 (en) * 2005-08-04 2007-02-08 Universite Laval Gelation of undenatured proteins with polysaccharides
KR100715815B1 (ko) 2005-11-08 2007-05-08 부경대학교 산학협력단 키토산-폴록사마 복합체의 제조방법
US10208158B2 (en) 2006-07-10 2019-02-19 Medipacs, Inc. Super elastic epoxy hydrogel
US8789536B2 (en) 2007-10-17 2014-07-29 The Invention Science Fund I, Llc Medical or veterinary digestive tract utilization systems and methods
US8303573B2 (en) 2007-10-17 2012-11-06 The Invention Science Fund I, Llc Medical or veterinary digestive tract utilization systems and methods
US8707964B2 (en) * 2007-10-31 2014-04-29 The Invention Science Fund I, Llc Medical or veterinary digestive tract utilization systems and methods
US20090105561A1 (en) * 2007-10-17 2009-04-23 Searete Llc, A Limited Liability Corporation Of The State Of Delaware Medical or veterinary digestive tract utilization systems and methods
US8808276B2 (en) * 2007-10-23 2014-08-19 The Invention Science Fund I, Llc Adaptive dispensation in a digestive tract
US8109920B2 (en) * 2007-10-31 2012-02-07 The Invention Science Fund I, Llc Medical or veterinary digestive tract utilization systems and methods
US8333754B2 (en) * 2007-10-31 2012-12-18 The Invention Science Fund I, Llc Medical or veterinary digestive tract utilization systems and methods
US8808271B2 (en) * 2007-10-31 2014-08-19 The Invention Science Fund I, Llc Medical or veterinary digestive tract utilization systems and methods
US20090163894A1 (en) * 2007-10-31 2009-06-25 Searete Llc, A Limited Liability Corporation Of The State Of Delaware Medical or veterinary digestive tract utilization systems and methods
US20090137866A1 (en) * 2007-11-28 2009-05-28 Searete Llc, A Limited Liability Corporation Of The State Delaware Medical or veterinary digestive tract utilization systems and methods
US20090139710A1 (en) * 2007-11-30 2009-06-04 Schlumberger Technology Corporation Swellable compositions and methods and devices for controlling them
WO2009073734A2 (en) 2007-12-03 2009-06-11 Medipacs, Inc. Fluid metering device
WO2009086067A2 (en) * 2007-12-28 2009-07-09 Boston Scientific Scimed, Inc. Particles for injection and processes fo forming the same
US9649331B2 (en) * 2009-08-27 2017-05-16 Ara Medical Llc Sprayable polymers as adhesion barriers
WO2011032011A1 (en) 2009-09-10 2011-03-17 Medipacs, Inc. Low profile actuator and improved method of caregiver controlled administration of therapeutics
US20130064896A1 (en) * 2009-12-29 2013-03-14 Laman Lynn Alani Gastroretentive Solid Oral Dosage Forms with Swellable Hydrophilic Polymer
US9500186B2 (en) 2010-02-01 2016-11-22 Medipacs, Inc. High surface area polymer actuator with gas mitigating components
CN101942098B (zh) * 2010-03-19 2012-05-30 中科院广州化学有限公司 一种具有化学交联特性的两亲性壳聚糖及其制备方法
US8668675B2 (en) 2010-11-03 2014-03-11 Flugen, Inc. Wearable drug delivery device having spring drive and sliding actuation mechanism
CN104302689A (zh) 2012-03-14 2015-01-21 麦德医像公司 含有过量活性分子的智能聚合物材料
EP3209288A1 (de) * 2014-09-25 2017-08-30 Manu Chaudhary Gerichtete stealth-nanopartikel (stn) zur oralen wirkstoffverabreichung
US20170362543A1 (en) * 2016-06-17 2017-12-21 The Procter & Gamble Company Delayed-Release Particles
GB202215227D0 (en) * 2022-10-14 2022-11-30 Univ Of Newcastle Composite material

Family Cites Families (26)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4034756A (en) * 1971-01-13 1977-07-12 Alza Corporation Osmotically driven fluid dispenser
US4320759A (en) * 1980-04-28 1982-03-23 Alza Corporation Dispenser with diffuser
US4713249A (en) 1981-11-12 1987-12-15 Schroeder Ulf Crystallized carbohydrate matrix for biologically active substances, a process of preparing said matrix, and the use thereof
US4783337A (en) * 1983-05-11 1988-11-08 Alza Corporation Osmotic system comprising plurality of members for dispensing drug
US4503030A (en) * 1983-06-06 1985-03-05 Alza Corporation Device for delivering drug to certain pH environments
US4627850A (en) * 1983-11-02 1986-12-09 Alza Corporation Osmotic capsule
US4717566A (en) * 1984-03-19 1988-01-05 Alza Corporation Dosage system and method of using same
US4814180A (en) * 1984-03-21 1989-03-21 Alza Corporation Agent dispenser comprising a semipermeable wall surrounding single-piece or two-piece container
ES8505250A3 (es) 1984-04-04 1985-05-16 Ulf Schroder Un procedimiento para producir una esfera o particula de hidratos de carbono
US4743247A (en) * 1984-08-13 1988-05-10 Alza Corporation Process for manufacturing dosage form
US4865598A (en) * 1985-08-16 1989-09-12 Alza Corporation Dispensing system for administering beneficial agent
US4871544A (en) * 1985-08-16 1989-10-03 Alza Corporation Ruminant dispensing device
US4966767A (en) * 1985-08-16 1990-10-30 Alza Corporation Ruminant dispensing device comprising agent displacement member
US4883667A (en) * 1985-08-16 1989-11-28 Alza Corporation Process for forming dispensing device
US4948592A (en) * 1986-05-09 1990-08-14 Alza Corporation Pulsed drug delivery
US4837111A (en) * 1988-03-21 1989-06-06 Alza Corporation Dosage form for dispensing drug for human therapy
US5226902A (en) * 1991-07-30 1993-07-13 University Of Utah Pulsatile drug delivery device using stimuli sensitive hydrogel
US5420197A (en) * 1994-01-13 1995-05-30 Hydromer, Inc. Gels formed by the interaction of polyvinylpyrrolidone with chitosan derivatives
US5620706A (en) * 1995-04-10 1997-04-15 Universite De Sherbrooke Polyionic insoluble hydrogels comprising xanthan and chitosan
TW389694B (en) * 1995-08-17 2000-05-11 Novartis Ag Compositions including o-carboxyalkyl chitosan and methods of use in ophthalmics
US5770712A (en) * 1997-03-14 1998-06-23 Virginia Tech Intellectual Properties, Inc. Crosslinked hydrogel beads from chitosan
US5904927A (en) * 1997-03-14 1999-05-18 Northeastern University Drug delivery using pH-sensitive semi-interpenetrating network hydrogels
US5864025A (en) * 1997-06-30 1999-01-26 Virginia Tech Intellectual Properties, Inc. Method of making magnetic, crosslinked chitosan support materials and products thereof
US6365185B1 (en) * 1998-03-26 2002-04-02 University Of Cincinnati Self-destructing, controlled release peroral drug delivery system
US6537584B1 (en) * 1999-11-12 2003-03-25 Macromed, Inc. Polymer blends that swell in an acidic environment and deswell in a basic environment
ES2259618T3 (es) * 1999-11-12 2006-10-16 Macromed, Inc. Mezclas de polimeros hinchables y deshinchables.

Also Published As

Publication number Publication date
CA2389251C (en) 2010-03-23
CN1181816C (zh) 2004-12-29
EP1240230A4 (de) 2004-12-01
AU1760501A (en) 2001-06-06
HK1052713A1 (en) 2003-09-26
BR0015521A (pt) 2002-11-19
DE60026357T2 (de) 2006-10-19
EP1240230B1 (de) 2006-03-01
BR0015521B1 (pt) 2013-04-02
ES2259618T3 (es) 2006-10-16
CA2389251A1 (en) 2001-05-17
ATE318846T1 (de) 2006-03-15
MXPA02004583A (es) 2002-09-02
CN1399655A (zh) 2003-02-26
US7182957B2 (en) 2007-02-27
AU775527B2 (en) 2004-08-05
US6730327B2 (en) 2004-05-04
WO2001034677A1 (en) 2001-05-17
WO2001034677A8 (en) 2001-10-11
HK1052713B (zh) 2005-08-19
EP1240230A1 (de) 2002-09-18
US20030139495A1 (en) 2003-07-24
US20030124189A1 (en) 2003-07-03

Similar Documents

Publication Publication Date Title
DE60026357D1 (de) An- und abschwellende polymermischungen
AR026448A1 (es) Mezclas de polimeros que se inflan en un medio acidico y se desinflan en un medio basico
Modi et al. Chitosan based mucoadhesive nanoparticles of ketoconazole for bioavailability enhancement: formulation, optimization, in vitro and ex vivo evaluation
TR200400295T2 (tr) Kimyasal olarak modifiye edilmiş ensülin'in akçiğer yoluyla verilmesi
TR199800902T2 (xx) Ecza form�lasyonlar�.
TR199901564T2 (xx) H�zl� ��z�lebilen ve tat-maskesi sa�layan dozaj ispen�iyari formu.
HRP20150110T1 (hr) Kompozicija koja sadrži uljne kapljice
Blemur et al. Carboxymethyl starch/alginate microspheres containing diamine oxidase for intestinal targeting
MXPA02001243A (es) Medios para crear una masa que tiene integridad estructural.
SE0003449D0 (sv) Anticancer compositions
WO2009066955A3 (en) Lyophilized pharmaceutical composition with improved stability containing taxane derivatives, and method of manufacturing the same
WO2002051385A8 (en) Solid dispersions of nitrate active principles
Ijaz et al. Design and in vitro evaluation of pH-sensitive crosslinked chitosan-grafted acrylic acid copolymer (CS-co-AA) for targeted drug delivery
Pradeep et al. Role of nanocellulose in industrial and pharmaceutical sectors-A review
Tan et al. Fabrication of radiation cross-linked diclofenac sodium loaded carboxymethyl sago pulp/chitosan hydrogel for enteric and sustained drug delivery
JP2009514884A (ja) 難溶性医薬活性剤の投与のためのカルボキシアルキルセルロースエステル
EP0776329A1 (de) Wasserlösliche polyen-konjugate
DE69906269D1 (de) Wässriges verfahren zur herstellung fester paroxetin-dispersionen
ATE232100T1 (de) Gegen magensaft geschützte omeprazol- mikrogranülen, herstellungsverfahren und pharmazeutische zubereitungen
JP2021138762A (ja) 経口フィルム製剤
ATE297440T1 (de) Dextran-maleinsäuremonoester und hydrogele daraus
Bajpai et al. Dynamics of controlled release of heparin from swellable crosslinked starch microspheres
US9867787B2 (en) Hypromellose-graft-chitosan and methods thereof for sustained drug delivery
DE60017444D1 (de) Pharmazeutische formulierungen auf basis fester dispersionen
DK1326592T3 (da) Anvendelse af polyethylenglycol (PEG) til fremstilling af et lægemiddel til behandling af forstoppelse

Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8327 Change in the person/name/address of the patent owner

Owner name: PROTHERICS SALT LAKE CITY, INC., WEST VALLEY C, US