BR0015521A - Processo de inchar e de desinchar misturas poliméricas - Google Patents
Processo de inchar e de desinchar misturas poliméricasInfo
- Publication number
- BR0015521A BR0015521A BR0015521-7A BR0015521A BR0015521A BR 0015521 A BR0015521 A BR 0015521A BR 0015521 A BR0015521 A BR 0015521A BR 0015521 A BR0015521 A BR 0015521A
- Authority
- BR
- Brazil
- Prior art keywords
- polymer
- environment
- blend
- polymer blend
- polymer blends
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08L—COMPOSITIONS OF MACROMOLECULAR COMPOUNDS
- C08L1/00—Compositions of cellulose, modified cellulose or cellulose derivatives
- C08L1/08—Cellulose derivatives
- C08L1/10—Esters of organic acids, i.e. acylates
- C08L1/12—Cellulose acetate
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2022—Organic macromolecular compounds
- A61K9/2031—Organic macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, polyethylene oxide, poloxamers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2022—Organic macromolecular compounds
- A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08J—WORKING-UP; GENERAL PROCESSES OF COMPOUNDING; AFTER-TREATMENT NOT COVERED BY SUBCLASSES C08B, C08C, C08F, C08G or C08H
- C08J3/00—Processes of treating or compounding macromolecular substances
- C08J3/005—Processes for mixing polymers
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08L—COMPOSITIONS OF MACROMOLECULAR COMPOUNDS
- C08L5/00—Compositions of polysaccharides or of their derivatives not provided for in groups C08L1/00 or C08L3/00
- C08L5/02—Dextran; Derivatives thereof
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08L—COMPOSITIONS OF MACROMOLECULAR COMPOUNDS
- C08L5/00—Compositions of polysaccharides or of their derivatives not provided for in groups C08L1/00 or C08L3/00
- C08L5/08—Chitin; Chondroitin sulfate; Hyaluronic acid; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2022—Organic macromolecular compounds
- A61K9/2027—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2022—Organic macromolecular compounds
- A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
- A61K9/2054—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Polymers & Plastics (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Epidemiology (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Medicinal Preparation (AREA)
- Compositions Of Macromolecular Compounds (AREA)
- Manufacture Of Porous Articles, And Recovery And Treatment Of Waste Products (AREA)
- Separation Using Semi-Permeable Membranes (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Immobilizing And Processing Of Enzymes And Microorganisms (AREA)
Abstract
"PROCESSO DE INCHAR E DE DESINCHAR MISTURAS POLIMéRICAS". A invenção refere-se a uma mistura polimérica é preparada dissolvendo quitosan e um segundo polímero em uma solução aquosa ácida para formar uma mistura polimérica aquosa, desidratando a dita mistura polimérica aquosa ácida e recuperando a dita mistura polimérica. O segundo polímero pode ser selecionado do grupo que consiste em poliéter glicóis incluindo polietileno glicóis; ésteres de celulose incluindo acetato de celulose; poloxâmeros; polissacarídeos incluindo dextran e guar; polivinilpirrolidonas; álcoois polivinílicos; e misturas ou copolímeros dos mesmos. Estas misturas poliméricas incham em um ambiente ácido e desincham em um ambiente mais neutro ou básico. Esta tecnologia é valiosa para aplicar material biologicamente ativo ou drogas em um ambiente que os circunda, especialmente o ambiente tal como é encontrado no trato gastrointestinal. Visto que as várias misturas poliméricas da presente invenção não são covalentemente ou ionicamente reticuladas, mas são fisicamente combinadas, cada polímero na mistura física mantém sua estrutura química original e, portanto, é seguro para a via oral ou outros vias de administração.
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US43888499A | 1999-11-12 | 1999-11-12 | |
US09/710,403 US6537584B1 (en) | 1999-11-12 | 2000-11-09 | Polymer blends that swell in an acidic environment and deswell in a basic environment |
PCT/US2000/030908 WO2001034677A1 (en) | 1999-11-12 | 2000-11-10 | Swelling and deswelling polymer blends |
Publications (2)
Publication Number | Publication Date |
---|---|
BR0015521A true BR0015521A (pt) | 2002-11-19 |
BR0015521B1 BR0015521B1 (pt) | 2013-04-02 |
Family
ID=27031834
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
BRPI0015521-7A BR0015521B1 (pt) | 1999-11-12 | 2000-11-10 | mistura polimÉrica que incha e desincha dependendo do ambiente e composiÇço contendo a referida mistura polimÉrica. |
Country Status (12)
Country | Link |
---|---|
US (2) | US7182957B2 (pt) |
EP (1) | EP1240230B1 (pt) |
CN (1) | CN1181816C (pt) |
AT (1) | ATE318846T1 (pt) |
AU (1) | AU775527B2 (pt) |
BR (1) | BR0015521B1 (pt) |
CA (1) | CA2389251C (pt) |
DE (1) | DE60026357T2 (pt) |
ES (1) | ES2259618T3 (pt) |
HK (1) | HK1052713B (pt) |
MX (1) | MXPA02004583A (pt) |
WO (1) | WO2001034677A1 (pt) |
Families Citing this family (34)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CA2389251C (en) * | 1999-11-12 | 2010-03-23 | Macromed, Inc. | Swelling and deswelling polymer blends |
JP2002044663A (ja) * | 2000-07-24 | 2002-02-08 | Canon Inc | 画像符号化装置及び方法、画像表示装置及び方法、画像処理システム並びに撮像装置 |
US6696618B2 (en) * | 2001-12-12 | 2004-02-24 | Kimberly-Clark Worldwide, Inc. | Absorbent composites exhibiting swelling/deswelling properties |
GB0130518D0 (en) * | 2001-12-21 | 2002-02-06 | Univ Gent | Pulsed bio-agent delivery systems based on degradable polymer solutions or hydrogels |
CN100413919C (zh) * | 2002-12-13 | 2008-08-27 | 上海爱普食品工业有限公司 | 复合型可食性壳聚糖膜的制备方法 |
US20050112151A1 (en) * | 2003-11-20 | 2005-05-26 | Horng Liou L. | Skin adherent hydrogels |
GB0329907D0 (en) * | 2003-12-23 | 2004-01-28 | Innomed Ltd | Compositions |
WO2006130117A1 (en) * | 2005-06-03 | 2006-12-07 | National University Of Singapore | Novel polymer blends and applications for their use in hollow polymer fibers |
EP1919956A4 (en) * | 2005-08-04 | 2010-02-17 | Lorraine Inst Nat Polytech | GELING NON-DENATURED PROTEINS WITH POLYSACCHARIDES |
KR100715815B1 (ko) | 2005-11-08 | 2007-05-08 | 부경대학교 산학협력단 | 키토산-폴록사마 복합체의 제조방법 |
WO2008079440A2 (en) | 2006-07-10 | 2008-07-03 | Medipacs, Inc. | Super elastic epoxy hydrogel |
US20090105561A1 (en) * | 2007-10-17 | 2009-04-23 | Searete Llc, A Limited Liability Corporation Of The State Of Delaware | Medical or veterinary digestive tract utilization systems and methods |
US8303573B2 (en) | 2007-10-17 | 2012-11-06 | The Invention Science Fund I, Llc | Medical or veterinary digestive tract utilization systems and methods |
US8789536B2 (en) | 2007-10-17 | 2014-07-29 | The Invention Science Fund I, Llc | Medical or veterinary digestive tract utilization systems and methods |
US8707964B2 (en) * | 2007-10-31 | 2014-04-29 | The Invention Science Fund I, Llc | Medical or veterinary digestive tract utilization systems and methods |
US8808276B2 (en) * | 2007-10-23 | 2014-08-19 | The Invention Science Fund I, Llc | Adaptive dispensation in a digestive tract |
US8333754B2 (en) * | 2007-10-31 | 2012-12-18 | The Invention Science Fund I, Llc | Medical or veterinary digestive tract utilization systems and methods |
US8109920B2 (en) * | 2007-10-31 | 2012-02-07 | The Invention Science Fund I, Llc | Medical or veterinary digestive tract utilization systems and methods |
US8808271B2 (en) * | 2007-10-31 | 2014-08-19 | The Invention Science Fund I, Llc | Medical or veterinary digestive tract utilization systems and methods |
US20090163894A1 (en) * | 2007-10-31 | 2009-06-25 | Searete Llc, A Limited Liability Corporation Of The State Of Delaware | Medical or veterinary digestive tract utilization systems and methods |
US20090137866A1 (en) * | 2007-11-28 | 2009-05-28 | Searete Llc, A Limited Liability Corporation Of The State Delaware | Medical or veterinary digestive tract utilization systems and methods |
US20090139710A1 (en) * | 2007-11-30 | 2009-06-04 | Schlumberger Technology Corporation | Swellable compositions and methods and devices for controlling them |
JP2011505520A (ja) | 2007-12-03 | 2011-02-24 | メディパックス インコーポレイテッド | 流体計量供給装置 |
US20090169639A1 (en) * | 2007-12-28 | 2009-07-02 | Boston Scientific Scimed, Inc. | Particles for injection and processes for forming the same |
US9649331B2 (en) * | 2009-08-27 | 2017-05-16 | Ara Medical Llc | Sprayable polymers as adhesion barriers |
US9238102B2 (en) | 2009-09-10 | 2016-01-19 | Medipacs, Inc. | Low profile actuator and improved method of caregiver controlled administration of therapeutics |
US20130064896A1 (en) * | 2009-12-29 | 2013-03-14 | Laman Lynn Alani | Gastroretentive Solid Oral Dosage Forms with Swellable Hydrophilic Polymer |
US9500186B2 (en) | 2010-02-01 | 2016-11-22 | Medipacs, Inc. | High surface area polymer actuator with gas mitigating components |
CN101942098B (zh) * | 2010-03-19 | 2012-05-30 | 中科院广州化学有限公司 | 一种具有化学交联特性的两亲性壳聚糖及其制备方法 |
US8668675B2 (en) | 2010-11-03 | 2014-03-11 | Flugen, Inc. | Wearable drug delivery device having spring drive and sliding actuation mechanism |
US10000605B2 (en) | 2012-03-14 | 2018-06-19 | Medipacs, Inc. | Smart polymer materials with excess reactive molecules |
WO2016046845A1 (en) * | 2014-09-25 | 2016-03-31 | Manu Chaudhary | Stealth, targeted nanoparticles (stn) for oral drug delivery |
WO2017218772A1 (en) * | 2016-06-17 | 2017-12-21 | The Procter & Gamble Company | Delayed-release particles |
GB202215227D0 (en) * | 2022-10-14 | 2022-11-30 | Univ Of Newcastle | Composite material |
Family Cites Families (26)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4034756A (en) | 1971-01-13 | 1977-07-12 | Alza Corporation | Osmotically driven fluid dispenser |
US4320759A (en) | 1980-04-28 | 1982-03-23 | Alza Corporation | Dispenser with diffuser |
US4713249A (en) | 1981-11-12 | 1987-12-15 | Schroeder Ulf | Crystallized carbohydrate matrix for biologically active substances, a process of preparing said matrix, and the use thereof |
US4783337A (en) | 1983-05-11 | 1988-11-08 | Alza Corporation | Osmotic system comprising plurality of members for dispensing drug |
US4503030A (en) * | 1983-06-06 | 1985-03-05 | Alza Corporation | Device for delivering drug to certain pH environments |
US4627850A (en) * | 1983-11-02 | 1986-12-09 | Alza Corporation | Osmotic capsule |
US4717566A (en) | 1984-03-19 | 1988-01-05 | Alza Corporation | Dosage system and method of using same |
US4814180A (en) | 1984-03-21 | 1989-03-21 | Alza Corporation | Agent dispenser comprising a semipermeable wall surrounding single-piece or two-piece container |
ES531286A0 (es) | 1984-04-04 | 1985-05-16 | Ulf Schroder | Un procedimiento para producir una esfera o particula de hidratos de carbono |
US4743247A (en) | 1984-08-13 | 1988-05-10 | Alza Corporation | Process for manufacturing dosage form |
US4966767A (en) * | 1985-08-16 | 1990-10-30 | Alza Corporation | Ruminant dispensing device comprising agent displacement member |
US4871544A (en) * | 1985-08-16 | 1989-10-03 | Alza Corporation | Ruminant dispensing device |
US4883667A (en) * | 1985-08-16 | 1989-11-28 | Alza Corporation | Process for forming dispensing device |
US4865598A (en) | 1985-08-16 | 1989-09-12 | Alza Corporation | Dispensing system for administering beneficial agent |
US4948592A (en) * | 1986-05-09 | 1990-08-14 | Alza Corporation | Pulsed drug delivery |
US4837111A (en) * | 1988-03-21 | 1989-06-06 | Alza Corporation | Dosage form for dispensing drug for human therapy |
US5226902A (en) | 1991-07-30 | 1993-07-13 | University Of Utah | Pulsatile drug delivery device using stimuli sensitive hydrogel |
US5420197A (en) * | 1994-01-13 | 1995-05-30 | Hydromer, Inc. | Gels formed by the interaction of polyvinylpyrrolidone with chitosan derivatives |
US5620706A (en) * | 1995-04-10 | 1997-04-15 | Universite De Sherbrooke | Polyionic insoluble hydrogels comprising xanthan and chitosan |
TW389694B (en) | 1995-08-17 | 2000-05-11 | Novartis Ag | Compositions including o-carboxyalkyl chitosan and methods of use in ophthalmics |
US5904927A (en) * | 1997-03-14 | 1999-05-18 | Northeastern University | Drug delivery using pH-sensitive semi-interpenetrating network hydrogels |
US5770712A (en) * | 1997-03-14 | 1998-06-23 | Virginia Tech Intellectual Properties, Inc. | Crosslinked hydrogel beads from chitosan |
US5864025A (en) * | 1997-06-30 | 1999-01-26 | Virginia Tech Intellectual Properties, Inc. | Method of making magnetic, crosslinked chitosan support materials and products thereof |
US6365185B1 (en) * | 1998-03-26 | 2002-04-02 | University Of Cincinnati | Self-destructing, controlled release peroral drug delivery system |
CA2389251C (en) * | 1999-11-12 | 2010-03-23 | Macromed, Inc. | Swelling and deswelling polymer blends |
US6537584B1 (en) * | 1999-11-12 | 2003-03-25 | Macromed, Inc. | Polymer blends that swell in an acidic environment and deswell in a basic environment |
-
2000
- 2000-11-10 CA CA2389251A patent/CA2389251C/en not_active Expired - Fee Related
- 2000-11-10 AT AT00980328T patent/ATE318846T1/de not_active IP Right Cessation
- 2000-11-10 MX MXPA02004583A patent/MXPA02004583A/es active IP Right Grant
- 2000-11-10 ES ES00980328T patent/ES2259618T3/es not_active Expired - Lifetime
- 2000-11-10 BR BRPI0015521-7A patent/BR0015521B1/pt not_active IP Right Cessation
- 2000-11-10 EP EP00980328A patent/EP1240230B1/en not_active Expired - Lifetime
- 2000-11-10 DE DE60026357T patent/DE60026357T2/de not_active Expired - Lifetime
- 2000-11-10 AU AU17605/01A patent/AU775527B2/en not_active Ceased
- 2000-11-10 WO PCT/US2000/030908 patent/WO2001034677A1/en active IP Right Grant
- 2000-11-10 CN CNB008155380A patent/CN1181816C/zh not_active Expired - Fee Related
-
2002
- 2002-12-20 US US10/327,814 patent/US7182957B2/en not_active Expired - Lifetime
- 2002-12-20 US US10/327,457 patent/US6730327B2/en not_active Expired - Lifetime
-
2003
- 2003-06-27 HK HK03104609.2A patent/HK1052713B/zh not_active IP Right Cessation
Also Published As
Publication number | Publication date |
---|---|
US6730327B2 (en) | 2004-05-04 |
MXPA02004583A (es) | 2002-09-02 |
WO2001034677A8 (en) | 2001-10-11 |
CN1399655A (zh) | 2003-02-26 |
EP1240230A4 (en) | 2004-12-01 |
US7182957B2 (en) | 2007-02-27 |
EP1240230A1 (en) | 2002-09-18 |
CA2389251A1 (en) | 2001-05-17 |
HK1052713A1 (en) | 2003-09-26 |
DE60026357T2 (de) | 2006-10-19 |
DE60026357D1 (de) | 2006-04-27 |
AU775527B2 (en) | 2004-08-05 |
CA2389251C (en) | 2010-03-23 |
CN1181816C (zh) | 2004-12-29 |
ATE318846T1 (de) | 2006-03-15 |
ES2259618T3 (es) | 2006-10-16 |
US20030139495A1 (en) | 2003-07-24 |
HK1052713B (zh) | 2005-08-19 |
WO2001034677A1 (en) | 2001-05-17 |
EP1240230B1 (en) | 2006-03-01 |
AU1760501A (en) | 2001-06-06 |
US20030124189A1 (en) | 2003-07-03 |
BR0015521B1 (pt) | 2013-04-02 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
B06A | Patent application procedure suspended [chapter 6.1 patent gazette] | ||
B09A | Decision: intention to grant [chapter 9.1 patent gazette] | ||
B09X | Republication of the decision to grant [chapter 9.1.3 patent gazette] | ||
B16A | Patent or certificate of addition of invention granted [chapter 16.1 patent gazette] |
Free format text: PRAZO DE VALIDADE: 10 (DEZ) ANOS CONTADOS A PARTIR DE 02/04/2013, OBSERVADAS AS CONDICOES LEGAIS. |
|
B21F | Lapse acc. art. 78, item iv - on non-payment of the annual fees in time |
Free format text: REFERENTE A 19A ANUIDADE. |
|
B24J | Lapse because of non-payment of annual fees (definitively: art 78 iv lpi, resolution 113/2013 art. 12) |
Free format text: EM VIRTUDE DA EXTINCAO PUBLICADA NA RPI 2539 DE 03-09-2019 E CONSIDERANDO AUSENCIA DE MANIFESTACAO DENTRO DOS PRAZOS LEGAIS, INFORMO QUE CABE SER MANTIDA A EXTINCAO DA PATENTE E SEUS CERTIFICADOS, CONFORME O DISPOSTO NO ARTIGO 12, DA RESOLUCAO 113/2013. |