DE60129576T2 - Ein thiazolidindionderivat und seine verwendung als antidiabetikum - Google Patents

Ein thiazolidindionderivat und seine verwendung als antidiabetikum Download PDF

Info

Publication number
DE60129576T2
DE60129576T2 DE60129576T DE60129576T DE60129576T2 DE 60129576 T2 DE60129576 T2 DE 60129576T2 DE 60129576 T DE60129576 T DE 60129576T DE 60129576 T DE60129576 T DE 60129576T DE 60129576 T2 DE60129576 T2 DE 60129576T2
Authority
DE
Germany
Prior art keywords
potassium salt
thiazolidine
pyridyl
ethoxy
benzyl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE60129576T
Other languages
German (de)
English (en)
Other versions
DE60129576D1 (de
Inventor
Michael C/o GlaxoSmi Tonbridge MILLAN
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
SmithKline Beecham Ltd
Original Assignee
SmithKline Beecham Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=9900427&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DE60129576(T2) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by SmithKline Beecham Ltd filed Critical SmithKline Beecham Ltd
Application granted granted Critical
Publication of DE60129576D1 publication Critical patent/DE60129576D1/de
Publication of DE60129576T2 publication Critical patent/DE60129576T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/10—Antimycotics

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Diabetes (AREA)
  • Public Health (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Obesity (AREA)
  • Hematology (AREA)
  • Endocrinology (AREA)
  • Emergency Medicine (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
DE60129576T 2000-09-29 2001-09-28 Ein thiazolidindionderivat und seine verwendung als antidiabetikum Expired - Lifetime DE60129576T2 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GB0023970 2000-09-29
GBGB0023970.7A GB0023970D0 (en) 2000-09-29 2000-09-29 Novel pharmaceutical
PCT/GB2001/004346 WO2002026736A1 (en) 2000-09-29 2001-09-28 A thiazolidinedione derivative and its use as antidiabetic

Publications (2)

Publication Number Publication Date
DE60129576D1 DE60129576D1 (de) 2007-09-06
DE60129576T2 true DE60129576T2 (de) 2008-04-17

Family

ID=9900427

Family Applications (1)

Application Number Title Priority Date Filing Date
DE60129576T Expired - Lifetime DE60129576T2 (de) 2000-09-29 2001-09-28 Ein thiazolidindionderivat und seine verwendung als antidiabetikum

Country Status (34)

Country Link
US (1) US20040038968A1 (ko)
EP (2) EP1325000B1 (ko)
JP (1) JP2004509960A (ko)
KR (2) KR100822135B1 (ko)
CN (2) CN101961333A (ko)
AP (1) AP1841A (ko)
AT (1) ATE368038T1 (ko)
AU (2) AU9203401A (ko)
BG (1) BG107678A (ko)
BR (1) BR0114364A (ko)
CA (1) CA2423978A1 (ko)
CY (1) CY1107767T1 (ko)
CZ (1) CZ2003849A3 (ko)
DE (1) DE60129576T2 (ko)
DK (1) DK1325000T3 (ko)
DZ (1) DZ3481A1 (ko)
EA (1) EA005110B1 (ko)
EC (1) ECSP034529A (ko)
ES (1) ES2290169T3 (ko)
GB (1) GB0023970D0 (ko)
HK (1) HK1058192A1 (ko)
HU (1) HUP0301199A3 (ko)
IL (2) IL155140A0 (ko)
MA (1) MA25913A1 (ko)
MX (1) MXPA03002867A (ko)
NO (2) NO324970B1 (ko)
NZ (1) NZ524932A (ko)
OA (1) OA12400A (ko)
PL (1) PL361157A1 (ko)
PT (1) PT1325000E (ko)
SK (1) SK3792003A3 (ko)
UA (1) UA76121C2 (ko)
WO (1) WO2002026736A1 (ko)
ZA (1) ZA200302438B (ko)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
HU225919B1 (en) * 1999-12-18 2007-12-28 Richter Gedeon Nyrt Thiazolidine-derivatives, process for their preparation pharmaceutical and intermediates
HUP0800755A2 (en) 2008-12-11 2010-09-28 Richter Gedeon Nyrt Crystalline forms of rosiglitazone

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5521201A (en) * 1987-09-04 1996-05-28 Beecham Group P.L.C. Method for treatment of atherosclerosis
ATE186724T1 (de) * 1987-09-04 1999-12-15 Beecham Group Plc Substituierte thiazolidindionderivate
GB9124513D0 (en) * 1991-11-19 1992-01-08 Smithkline Beecham Plc Novel process
GB9308487D0 (en) * 1993-04-23 1993-06-09 Smithkline Beecham Plc Novel compounds
GB9712866D0 (en) * 1997-06-18 1997-08-20 Smithkline Beecham Plc Novel method of treatment
GB9723295D0 (en) * 1997-11-04 1998-01-07 Smithkline Beecham Plc Novel process
CN1183130C (zh) * 1999-09-24 2005-01-05 中国人民解放军军事医学科学院毒物药物研究所 噻唑烷类衍生物及其医药用途
HU225919B1 (en) * 1999-12-18 2007-12-28 Richter Gedeon Nyrt Thiazolidine-derivatives, process for their preparation pharmaceutical and intermediates

Also Published As

Publication number Publication date
UA76121C2 (en) 2006-07-17
EA200300423A1 (ru) 2003-08-28
IL155140A0 (en) 2003-10-31
BG107678A (bg) 2003-11-28
EP1325000A1 (en) 2003-07-09
EP1795531A1 (en) 2007-06-13
SK3792003A3 (en) 2004-04-06
IL155140A (en) 2010-06-30
BR0114364A (pt) 2003-12-09
NO324970B1 (no) 2008-01-14
AU9203401A (en) 2002-04-08
EA005110B1 (ru) 2004-10-28
GB0023970D0 (en) 2000-11-15
HUP0301199A3 (en) 2005-04-28
CZ2003849A3 (cs) 2004-03-17
HUP0301199A2 (hu) 2003-11-28
CY1107767T1 (el) 2013-04-18
CN1620453B (zh) 2010-12-08
KR20070089258A (ko) 2007-08-30
NO20031434D0 (no) 2003-03-28
CN101961333A (zh) 2011-02-02
AP1841A (en) 2008-04-30
ES2290169T3 (es) 2008-02-16
DZ3481A1 (fr) 2002-04-04
JP2004509960A (ja) 2004-04-02
EP1325000B1 (en) 2007-07-25
KR100822135B1 (ko) 2008-04-15
NZ524932A (en) 2005-06-24
HK1058192A1 (en) 2004-05-07
ZA200302438B (en) 2004-04-28
CA2423978A1 (en) 2002-04-04
ATE368038T1 (de) 2007-08-15
ECSP034529A (es) 2003-05-26
US20040038968A1 (en) 2004-02-26
KR20030032058A (ko) 2003-04-23
DK1325000T3 (da) 2007-11-12
AU2001292034B2 (en) 2005-04-21
PL361157A1 (en) 2004-09-20
NO20075507L (no) 2003-05-27
MA25913A1 (fr) 2003-10-01
MXPA03002867A (es) 2004-12-06
DE60129576D1 (de) 2007-09-06
OA12400A (en) 2004-09-06
CN1620453A (zh) 2005-05-25
NO20031434L (no) 2003-05-27
PT1325000E (pt) 2007-10-25
AP2003002766A0 (en) 2003-03-31
WO2002026736A1 (en) 2002-04-04

Similar Documents

Publication Publication Date Title
DE60112729T2 (de) Hcl-salze von 5-[4-[2-(n-methyl-n-(2-pyridyl)amino)ethoxy]benzyl]thiazolidin-2,4-dion
DE60004658T2 (de) Thiazolidindionderivat und seine verwendung als antidiabetikum
DE60004196T2 (de) Polymorph von 5-[4-[2-(n-methyl-n-(2-pyrdyl)amino)äthoxy]benzyl]thiazolidin-2,4-dion, maleinsäuresalz
HRP20000404A2 (en) Substituted thiazolidinedione derivative, process for its preparation and its pharmaceutical use
DE60133746T2 (de) Tartratsalze eines thiazolidinedione derivats
DE60011419T2 (de) Thiazolidindionderivat und seine verwendung als antidiabetikum
DE60212434T2 (de) Rosiglitazon-edisylate und ihre verwendung als antidiabetika
DE60122580T2 (de) 5-4'-2'-(n-methyl-n-(2-pyridyl)amino) ethoxy!benzyl!thiazolidin-2,4-dion mesylatsalz
DE60112310T2 (de) Das Hydrochloridsalz von 5-[4-[2-(N-Methyl-N-(2-Pyridyl)Amino)Ethoxy]BenzylThiazolidin-2,4-Dion
DE60129576T2 (de) Ein thiazolidindionderivat und seine verwendung als antidiabetikum
DE60124119T2 (de) Ein thiazolidindionderivat und seine verwendung als antidiabetikum
DE60115062T2 (de) Thiazolidindionderivat und seine verwendung als antidiabetikum
DE60132461T2 (de) Tartratsalze eines thiazolidindion-derivats
US20070185167A1 (en) Sodium salts of 5-[4-[2-(n-methyl-n-(2-pyridyl)amino)ethoxy]benzyl]thiazolidine-2,4-dione
DE60132897T2 (de) Tartratsalze eines thiazolidindionderivats
DE60217168T2 (de) 5-(4-(2-(n-methyl-n-(2-pyridyl)amino)ethoxy)benzyl)thiazolidine-2,4-dion-benzolsulfonat; prozess zu seiner herstellung; polymorphe i, ii und iii davon; und seine verwendung als pharmazeutischer wirkstoff
BG107357A (bg) Тиазолидиндионова сол за лечение hа захарен диабеt
BG107605A (bg) Тартаратни соли на тиазолидиндионово производно
SK17152002A3 (sk) Hydrojodid 5-[4-[2-(N-metyl-N-(2-pyridyl)amíno)etoxy]- benzyl]tiazolidín-2,4-diónu ako liečivo
US20040102485A1 (en) Tartrate salt of thiazolidinedione derivative

Legal Events

Date Code Title Description
8363 Opposition against the patent