DE60034155T2 - Adamantanderivate zur Behandlung von entzündlichen, immunologischen und kardiovaskulären Erkrankungen - Google Patents

Adamantanderivate zur Behandlung von entzündlichen, immunologischen und kardiovaskulären Erkrankungen Download PDF

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Publication number
DE60034155T2
DE60034155T2 DE60034155T DE60034155T DE60034155T2 DE 60034155 T2 DE60034155 T2 DE 60034155T2 DE 60034155 T DE60034155 T DE 60034155T DE 60034155 T DE60034155 T DE 60034155T DE 60034155 T2 DE60034155 T2 DE 60034155T2
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compound
formula
solvate
acceptable salt
pharmaceutically acceptable
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DE60034155D1 (de
Inventor
Mark AstraZeneca Loughborough Furber
Michael Vertex Pharm Abingdon Mortimore
Lilian AstraZeneca Loughborough Alcaraz
Timothy AstraZeneca Loughborough Luker
Philip AstraZeneca Loughborough Thorne
Paul AstraZeneca Loughborough Willis
Austen AstraZeneca Loughborough Pimm
Moya AstraZeneca Loughborough Caffrey
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AstraZeneca AB
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Priority claimed from SE9904651A external-priority patent/SE9904651D0/xx
Priority claimed from GB0015744A external-priority patent/GB0015744D0/en
Priority claimed from GB0017942A external-priority patent/GB0017942D0/en
Application filed by AstraZeneca AB filed Critical AstraZeneca AB
Publication of DE60034155D1 publication Critical patent/DE60034155D1/de
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    • C07C235/44—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups bound to carbon atoms of six-membered aromatic rings and singly-bound oxygen atoms bound to the same carbon skeleton with carbon atoms of carboxamide groups and singly-bound oxygen atoms bound to carbon atoms of the same non-condensed six-membered aromatic ring
    • C07C235/46—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups bound to carbon atoms of six-membered aromatic rings and singly-bound oxygen atoms bound to the same carbon skeleton with carbon atoms of carboxamide groups and singly-bound oxygen atoms bound to carbon atoms of the same non-condensed six-membered aromatic ring having the nitrogen atoms of the carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms
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    • C07D233/56—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, attached to ring carbon atoms
    • C07D233/61—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, attached to ring carbon atoms with hydrocarbon radicals, substituted by nitrogen atoms not forming part of a nitro radical, attached to ring nitrogen atoms
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    • C07D233/64—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with substituted hydrocarbon radicals attached to ring carbon atoms, e.g. histidine
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    • C07C2601/14—The ring being saturated
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    • C07C2603/74—Adamantanes

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  • Chemical Kinetics & Catalysis (AREA)
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  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
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  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Diabetes (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Hematology (AREA)
  • Pulmonology (AREA)
  • Rheumatology (AREA)
  • Biomedical Technology (AREA)
  • Cardiology (AREA)
  • Oncology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Dermatology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Emergency Medicine (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Hospice & Palliative Care (AREA)
  • Pain & Pain Management (AREA)
  • Communicable Diseases (AREA)
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DE60034155T 1999-12-17 2000-12-12 Adamantanderivate zur Behandlung von entzündlichen, immunologischen und kardiovaskulären Erkrankungen Expired - Lifetime DE60034155T2 (de)

Applications Claiming Priority (6)

Application Number Priority Date Filing Date Title
SE9904651 1999-12-17
SE9904651A SE9904651D0 (sv) 1999-12-17 1999-12-17 Novel compounds
GB0015744A GB0015744D0 (en) 2000-06-27 2000-06-27 Novel compounds
GB0015744 2000-06-27
GB0017942A GB0017942D0 (en) 2000-07-22 2000-07-22 Novel compounds
GB0017942 2000-07-22

Publications (2)

Publication Number Publication Date
DE60034155D1 DE60034155D1 (de) 2007-05-10
DE60034155T2 true DE60034155T2 (de) 2007-12-13

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Family Applications (4)

Application Number Title Priority Date Filing Date
DE60032823T Expired - Lifetime DE60032823T2 (de) 1999-12-17 2000-12-12 Adamantanderivate zur Behandlung von entzündlichen, immunologischen und kardiovaskulären Erkrankungen
DE60034155T Expired - Lifetime DE60034155T2 (de) 1999-12-17 2000-12-12 Adamantanderivate zur Behandlung von entzündlichen, immunologischen und kardiovaskulären Erkrankungen
DE60009147T Expired - Lifetime DE60009147T2 (de) 1999-12-17 2000-12-12 Admantan derivate
DE60036968T Expired - Lifetime DE60036968T2 (de) 1999-12-17 2000-12-12 Adamantanderivate zur Behandlung von entzündlichen, immunologischen und kardiovaskulären Erkrankungen

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DE60032823T Expired - Lifetime DE60032823T2 (de) 1999-12-17 2000-12-12 Adamantanderivate zur Behandlung von entzündlichen, immunologischen und kardiovaskulären Erkrankungen

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Application Number Title Priority Date Filing Date
DE60009147T Expired - Lifetime DE60009147T2 (de) 1999-12-17 2000-12-12 Admantan derivate
DE60036968T Expired - Lifetime DE60036968T2 (de) 1999-12-17 2000-12-12 Adamantanderivate zur Behandlung von entzündlichen, immunologischen und kardiovaskulären Erkrankungen

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US (5) US6881754B2 (enExample)
EP (5) EP1352897B1 (enExample)
JP (2) JP3710418B2 (enExample)
KR (2) KR20070012883A (enExample)
CN (1) CN1312120C (enExample)
AR (1) AR035325A1 (enExample)
AT (4) ATE358117T1 (enExample)
AU (2) AU780506B2 (enExample)
BR (1) BRPI0016395B8 (enExample)
CA (1) CA2393352C (enExample)
CO (1) CO5251381A1 (enExample)
CY (3) CY1106357T1 (enExample)
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