PT1352897E - Derivados de adamantano para o tratamento de doenças inflamatórias, imunitárias e cardiovasculares - Google Patents

Derivados de adamantano para o tratamento de doenças inflamatórias, imunitárias e cardiovasculares Download PDF

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Publication number
PT1352897E
PT1352897E PT03013991T PT03013991T PT1352897E PT 1352897 E PT1352897 E PT 1352897E PT 03013991 T PT03013991 T PT 03013991T PT 03013991 T PT03013991 T PT 03013991T PT 1352897 E PT1352897 E PT 1352897E
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PT
Portugal
Prior art keywords
chloro
tricyclo
dec
ylmethyl
propyl
Prior art date
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PT03013991T
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English (en)
Portuguese (pt)
Inventor
Philip Thorne
Lilian Alcaraz
Mark Furber
Michael Mortimore
Timothy Luker
Paul Willis
Austen Pimm
Moya Caffrey
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Astrazeneca Ab
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Filing date
Publication date
Priority claimed from SE9904651A external-priority patent/SE9904651D0/xx
Priority claimed from GB0015744A external-priority patent/GB0015744D0/en
Priority claimed from GB0017942A external-priority patent/GB0017942D0/en
Application filed by Astrazeneca Ab filed Critical Astrazeneca Ab
Publication of PT1352897E publication Critical patent/PT1352897E/pt

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    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C235/00Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms
    • C07C235/42Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups bound to carbon atoms of six-membered aromatic rings and singly-bound oxygen atoms bound to the same carbon skeleton
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    • C07C235/00Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms
    • C07C235/42Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups bound to carbon atoms of six-membered aromatic rings and singly-bound oxygen atoms bound to the same carbon skeleton
    • C07C235/44Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups bound to carbon atoms of six-membered aromatic rings and singly-bound oxygen atoms bound to the same carbon skeleton with carbon atoms of carboxamide groups and singly-bound oxygen atoms bound to carbon atoms of the same non-condensed six-membered aromatic ring
    • C07C235/46Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups bound to carbon atoms of six-membered aromatic rings and singly-bound oxygen atoms bound to the same carbon skeleton with carbon atoms of carboxamide groups and singly-bound oxygen atoms bound to carbon atoms of the same non-condensed six-membered aromatic ring having the nitrogen atoms of the carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms
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    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
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    • C07C235/70Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups and doubly-bound oxygen atoms bound to the same carbon skeleton
    • C07C235/84Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups and doubly-bound oxygen atoms bound to the same carbon skeleton with the carbon atom of at least one of the carboxamide groups bound to a carbon atom of a six-membered aromatic ring
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    • C07C237/30Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atom of at least one of the carboxamide groups bound to a carbon atom of a non-condensed six-membered aromatic ring of the carbon skeleton having the nitrogen atom of the carboxamide group bound to hydrogen atoms or to acyclic carbon atoms
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    • C07D233/56Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, attached to ring carbon atoms
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    • C07D233/64Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with substituted hydrocarbon radicals attached to ring carbon atoms, e.g. histidine
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  • Diabetes (AREA)
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  • Dermatology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Oncology (AREA)
  • Neurology (AREA)
  • Cardiology (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Vascular Medicine (AREA)
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  • Obesity (AREA)
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  • Communicable Diseases (AREA)
  • Psychiatry (AREA)
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PT03013991T 1999-12-17 2000-12-12 Derivados de adamantano para o tratamento de doenças inflamatórias, imunitárias e cardiovasculares PT1352897E (pt)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
SE9904651A SE9904651D0 (sv) 1999-12-17 1999-12-17 Novel compounds
GB0015744A GB0015744D0 (en) 2000-06-27 2000-06-27 Novel compounds
GB0017942A GB0017942D0 (en) 2000-07-22 2000-07-22 Novel compounds

Publications (1)

Publication Number Publication Date
PT1352897E true PT1352897E (pt) 2007-03-30

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Family Applications (4)

Application Number Title Priority Date Filing Date
PT03013990T PT1352896E (pt) 1999-12-17 2000-12-12 Derivados de adamantano para o tratamento de doenças inflamatórias, imunitárias e cardiovasculares
PT03013989T PT1352895E (pt) 1999-12-17 2000-12-12 Derivados de adamantano para o tratamento de doenças inflamatórias, imunitárias e cardiovasculares
PT03013991T PT1352897E (pt) 1999-12-17 2000-12-12 Derivados de adamantano para o tratamento de doenças inflamatórias, imunitárias e cardiovasculares
PT00986155T PT1242364E (pt) 1999-12-17 2000-12-12 Derivados de adamantano

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Application Number Title Priority Date Filing Date
PT03013990T PT1352896E (pt) 1999-12-17 2000-12-12 Derivados de adamantano para o tratamento de doenças inflamatórias, imunitárias e cardiovasculares
PT03013989T PT1352895E (pt) 1999-12-17 2000-12-12 Derivados de adamantano para o tratamento de doenças inflamatórias, imunitárias e cardiovasculares

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Application Number Title Priority Date Filing Date
PT00986155T PT1242364E (pt) 1999-12-17 2000-12-12 Derivados de adamantano

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JP (2) JP3710418B2 (enExample)
KR (2) KR20070012883A (enExample)
CN (1) CN1312120C (enExample)
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NZ (1) NZ519378A (enExample)
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PT (4) PT1352896E (enExample)
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TR (1) TR200401432T4 (enExample)
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Families Citing this family (44)

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Publication number Priority date Publication date Assignee Title
SE9904505D0 (sv) 1999-12-09 1999-12-09 Astra Pharma Prod Novel compounds
TWI258462B (en) * 1999-12-17 2006-07-21 Astrazeneca Ab Adamantane derivative compounds, process for preparing the same and pharmaceutical composition comprising the same
SE9904738D0 (sv) 1999-12-22 1999-12-22 Astra Pharma Prod Novel compounds
PA8557501A1 (es) 2001-11-12 2003-06-30 Pfizer Prod Inc Benzamida, heteroarilamida y amidas inversas
WO2003042190A1 (en) 2001-11-12 2003-05-22 Pfizer Products Inc. N-alkyl-adamantyl derivatives as p2x7-receptor antagonists
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