DE2907460C2 - - Google Patents
Info
- Publication number
- DE2907460C2 DE2907460C2 DE2907460A DE2907460A DE2907460C2 DE 2907460 C2 DE2907460 C2 DE 2907460C2 DE 2907460 A DE2907460 A DE 2907460A DE 2907460 A DE2907460 A DE 2907460A DE 2907460 C2 DE2907460 C2 DE 2907460C2
- Authority
- DE
- Germany
- Prior art keywords
- cyclosporin
- composition
- compositions
- composition according
- weight
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/14—Esters of carboxylic acids, e.g. fatty acid monoglycerides, medium-chain triglycerides, parabens or PEG fatty acid esters
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
- A61K38/12—Cyclic peptides, e.g. bacitracins; Polymyxins; Gramicidins S, C; Tyrocidins A, B or C
- A61K38/13—Cyclosporins
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
- A61K9/127—Liposomes
- A61K9/1274—Non-vesicle bilayer structures, e.g. liquid crystals, tubules, cubic phases, cochleates; Sponge phases
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/4841—Filling excipients; Inactive ingredients
- A61K9/4858—Organic compounds
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S930/00—Peptide or protein sequence
- Y10S930/01—Peptide or protein sequence
- Y10S930/27—Cyclic peptide or cyclic protein
Description
- a) einem nicht ionischen Ester eines Triglycerids mit einem Polyalkylenglykol,
- b) einem pflanzlichen Öl und
- c) Ethanol.
- a) Trinklösungen,
- b) Trinkemulsionen,
- c) Injektionslösungen,
- d) in Kapseln befindliche Lösungen.
- i) 300 mg/ml Labrafil M 1944 CS;
- ii) 100 mg/ml Ethanol (absolut);
- iii) 100 mg/ml Cyclosporin A (Trockengewicht); und
- iv) ca. 425 mg/ml Olivenöl
Claims (8)
- a) einem nicht ionischen Ester eines Triglyzerids mit einem Polyalkylenglykol,
- b) einem pflanzlichen Öl und
- c) Ethanol.
- a) einem nicht ionischen Ester eines Triglycerids mit einem Polyalkylenglykol,
- b) einem pflanzlichen Öl und
- c) Ethanol.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CH246178A CH636013A5 (en) | 1978-03-07 | 1978-03-07 | More readily absorbable pharmaceutical composition |
CH863478 | 1978-08-14 |
Publications (2)
Publication Number | Publication Date |
---|---|
DE2907460A1 DE2907460A1 (de) | 1979-09-13 |
DE2907460C2 true DE2907460C2 (de) | 1990-09-27 |
Family
ID=25690510
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE19792907460 Granted DE2907460A1 (de) | 1978-03-07 | 1979-02-26 | Neue resorbierbare galenische kompositionen |
Country Status (27)
Country | Link |
---|---|
US (1) | US4388307A (de) |
JP (1) | JPS54132223A (de) |
AR (1) | AR223667A1 (de) |
AT (1) | AT375828B (de) |
AU (1) | AU528714B2 (de) |
CA (1) | CA1139667A (de) |
CY (1) | CY1285A (de) |
DD (1) | DD142149A5 (de) |
DE (1) | DE2907460A1 (de) |
DK (1) | DK154539C (de) |
ES (1) | ES478295A1 (de) |
FI (1) | FI65914C (de) |
FR (1) | FR2419072A1 (de) |
GB (1) | GB2015339B (de) |
HK (1) | HK48585A (de) |
IE (1) | IE48016B1 (de) |
IL (1) | IL56790A (de) |
IT (1) | IT1115038B (de) |
KE (1) | KE3516A (de) |
MY (1) | MY8500134A (de) |
NL (2) | NL187260C (de) |
NO (2) | NO152635C (de) |
NZ (1) | NZ189819A (de) |
PH (1) | PH15159A (de) |
PT (1) | PT69309A (de) |
SE (1) | SE445174B (de) |
SG (1) | SG14785G (de) |
Families Citing this family (154)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0034567B1 (de) * | 1980-02-14 | 1984-11-07 | Sandoz Ag | Verfahren zur Totalsynthese von Cyclosporinen und neue Cyclosporine |
DE3224619A1 (de) * | 1981-07-14 | 1983-05-19 | Freund Industrial Co., Ltd., Tokyo | Orale pharmazeutische zusammensetzung |
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EP0127426A1 (de) * | 1983-05-23 | 1984-12-05 | Takeda Chemical Industries, Ltd. | Perkutane pharmazeutische Zusammensetzungen zur äusserlichen Anwendung |
US5639724A (en) * | 1984-07-24 | 1997-06-17 | Sandoz Ltd. | Cyclosporin galenic forms |
GB8903804D0 (en) * | 1989-02-20 | 1989-04-05 | Sandoz Ltd | Improvements in or relating to organic compounds |
US5474980A (en) * | 1984-10-04 | 1995-12-12 | Monsanto Company | Prolonged release of biologically active somatotropins |
US5411951A (en) * | 1984-10-04 | 1995-05-02 | Monsanto Company | Prolonged release of biologically active somatotropin |
US4727035A (en) * | 1984-11-14 | 1988-02-23 | Mahoney Walter C | Immunoassay for cyclosporin |
US4576645A (en) * | 1984-12-06 | 1986-03-18 | Block Drug Co., Inc. | Whipped gel composition |
JPS61280435A (ja) * | 1985-04-04 | 1986-12-11 | Kanji Takada | サイクロスポリン類のリンパ指向性製剤 |
US4775659A (en) * | 1985-08-19 | 1988-10-04 | Eli Lilly And Company | Injectable semi-solid formulations |
GB8524421D0 (en) * | 1985-10-03 | 1985-11-06 | Boots Co Plc | Therapeutic agents |
US4764381A (en) * | 1985-12-06 | 1988-08-16 | Key Pharmaceuticals, Inc. | Percutaneous penetration enhancer of oleic acid and 2-ethyl-1, 3-hexanediol |
WO1987006463A1 (en) * | 1986-05-02 | 1987-11-05 | Brigham And Women's Hospital | A composition having reduced nephrotoxicity comprising a fatty acid containing component and cyclosporine |
US5118493A (en) * | 1986-05-02 | 1992-06-02 | Brigham And Women's Hospital | Composition having reduced nephrotoxocity comprising a fatty acid containing component and cyclosporine |
KR880012221A (ko) * | 1987-04-13 | 1988-11-26 | 사노 가즈오 | 에스테르 또는 아미드를 활성성분으로 함유하는 약제 조성물 |
JP2577049B2 (ja) * | 1987-06-04 | 1997-01-29 | 三共株式会社 | シクロスポリン製剤 |
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DE3830494B4 (de) * | 1987-09-15 | 2006-05-18 | Novartis Ag | Wasserlösliche Monoester als Solubilisatoren für pharmakologische Wirkstoffe und pharmazeutische Hilfsstoffe |
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- 1979-02-27 FR FR7904989A patent/FR2419072A1/fr active Granted
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- 1979-03-02 GB GB7907395A patent/GB2015339B/en not_active Expired
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- 1979-03-02 NL NLAANVRAGE7901703,A patent/NL187260C/xx active Protection Beyond IP Right Term
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- 1979-03-05 AT AT0163779A patent/AT375828B/de not_active IP Right Cessation
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- 1979-03-06 AU AU44862/79A patent/AU528714B2/en not_active Expired
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1982
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1993
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