DE2848965A1 - Verfahren zur herstellung von membranproteinen aus neisseria meningitidis und diese enthaltende vaccine - Google Patents

Verfahren zur herstellung von membranproteinen aus neisseria meningitidis und diese enthaltende vaccine

Info

Publication number
DE2848965A1
DE2848965A1 DE19782848965 DE2848965A DE2848965A1 DE 2848965 A1 DE2848965 A1 DE 2848965A1 DE 19782848965 DE19782848965 DE 19782848965 DE 2848965 A DE2848965 A DE 2848965A DE 2848965 A1 DE2848965 A1 DE 2848965A1
Authority
DE
Germany
Prior art keywords
neisseria meningitidis
membrane proteins
detergent
minutes
vaccine containing
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
DE19782848965
Other languages
German (de)
English (en)
Inventor
Gerhard Dipl Chem Guthoehrlein
Torsten Bertil Dr Helting
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Siemens Healthcare Diagnostics GmbH Germany
Original Assignee
Behringwerke AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Behringwerke AG filed Critical Behringwerke AG
Priority to DE19782848965 priority Critical patent/DE2848965A1/de
Priority to ES485715A priority patent/ES485715A1/es
Priority to AT79104391T priority patent/ATE857T1/de
Priority to DE7979104391T priority patent/DE2962526D1/de
Priority to EP79104391A priority patent/EP0011243B1/de
Priority to JP14456179A priority patent/JPS5566519A/ja
Priority to CA000339541A priority patent/CA1142083A/en
Priority to MX10131579U priority patent/MX5941E/es
Priority to AU52682/79A priority patent/AU533386B2/en
Priority to IL58673A priority patent/IL58673A/xx
Priority to DK475779A priority patent/DK154841C/da
Publication of DE2848965A1 publication Critical patent/DE2848965A1/de
Withdrawn legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/02—Bacterial antigens
    • A61K39/095—Neisseria

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
DE19782848965 1978-11-11 1978-11-11 Verfahren zur herstellung von membranproteinen aus neisseria meningitidis und diese enthaltende vaccine Withdrawn DE2848965A1 (de)

Priority Applications (11)

Application Number Priority Date Filing Date Title
DE19782848965 DE2848965A1 (de) 1978-11-11 1978-11-11 Verfahren zur herstellung von membranproteinen aus neisseria meningitidis und diese enthaltende vaccine
ES485715A ES485715A1 (es) 1978-11-11 1979-11-06 Procedimiento mejorado para la preparacion de proteinas de membranas
AT79104391T ATE857T1 (de) 1978-11-11 1979-11-08 Verfahren zur herstellung von membranproteinen aus neisseria meningitidis und diese enthaltende vaccine.
DE7979104391T DE2962526D1 (en) 1978-11-11 1979-11-08 Process for preparing membrane proteins from neisseria meningitidis and vaccines containing them
EP79104391A EP0011243B1 (de) 1978-11-11 1979-11-08 Verfahren zur Herstellung von Membranproteinen aus Neisseria meningitidis und diese enthaltende Vaccine
JP14456179A JPS5566519A (en) 1978-11-11 1979-11-09 Manufacture of membrane protein and vaccine containing it
CA000339541A CA1142083A (en) 1978-11-11 1979-11-09 Process for the isolation of membrane proteins from neisseria meningitidis and vaccines containing same
MX10131579U MX5941E (es) 1978-11-11 1979-11-09 Procedimiento mejorado para la preparacion de membranoproteinas a partir de neisseria meningitidis grupo"b"
AU52682/79A AU533386B2 (en) 1978-11-11 1979-11-09 Isolation of membrane proteins from neisseria meningitidis and vaccines containing same
IL58673A IL58673A (en) 1978-11-11 1979-11-09 Process for the isolation of membrane proteins from neisseria meningitidis and vaccines containing same
DK475779A DK154841C (da) 1978-11-11 1979-11-09 Fremgangsmaade til fremstilling af membranproteiner ud fra neisseria meningitidis

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19782848965 DE2848965A1 (de) 1978-11-11 1978-11-11 Verfahren zur herstellung von membranproteinen aus neisseria meningitidis und diese enthaltende vaccine

Publications (1)

Publication Number Publication Date
DE2848965A1 true DE2848965A1 (de) 1980-05-22

Family

ID=6054405

Family Applications (2)

Application Number Title Priority Date Filing Date
DE19782848965 Withdrawn DE2848965A1 (de) 1978-11-11 1978-11-11 Verfahren zur herstellung von membranproteinen aus neisseria meningitidis und diese enthaltende vaccine
DE7979104391T Expired DE2962526D1 (en) 1978-11-11 1979-11-08 Process for preparing membrane proteins from neisseria meningitidis and vaccines containing them

Family Applications After (1)

Application Number Title Priority Date Filing Date
DE7979104391T Expired DE2962526D1 (en) 1978-11-11 1979-11-08 Process for preparing membrane proteins from neisseria meningitidis and vaccines containing them

Country Status (9)

Country Link
EP (1) EP0011243B1 (enExample)
JP (1) JPS5566519A (enExample)
AT (1) ATE857T1 (enExample)
AU (1) AU533386B2 (enExample)
CA (1) CA1142083A (enExample)
DE (2) DE2848965A1 (enExample)
DK (1) DK154841C (enExample)
ES (1) ES485715A1 (enExample)
IL (1) IL58673A (enExample)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4317811A (en) 1980-09-11 1982-03-02 Merck & Co., Inc. Herpes simplex type 1 subunit vaccine
US12109243B2 (en) 2017-09-08 2024-10-08 Evelo Biosciences, Inc. Bacterial extracellular vesicles

Families Citing this family (48)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU563317B2 (en) * 1982-12-02 1987-07-02 Rockefeller University, The Iga binding antibody
US7118757B1 (en) 1988-12-19 2006-10-10 Wyeth Holdings Corporation Meningococcal class 1 outer-membrane protein vaccine
US8007815B1 (en) 1998-05-29 2011-08-30 Novartis Ag Combination meningitidis B/C vaccines
CN100338218C (zh) 1999-05-19 2007-09-19 启龙股份公司 组合式奈瑟球菌组合物
GB9918319D0 (en) 1999-08-03 1999-10-06 Smithkline Beecham Biolog Vaccine composition
GB9928196D0 (en) 1999-11-29 2000-01-26 Chiron Spa Combinations of B, C and other antigens
ES2507100T3 (es) 2000-01-17 2014-10-14 Novartis Vaccines And Diagnostics S.R.L. Vacuna OMV suplementada contra meningococo
GB0103171D0 (en) 2001-02-08 2001-03-28 Smithkline Beecham Biolog Vaccine composition
PT1524993E (pt) * 2002-08-02 2013-06-12 Glaxosmithkline Biolog Sa Composições de vacina de neisseria compreendendo uma combinação de antigénios
GB0220194D0 (en) 2002-08-30 2002-10-09 Chiron Spa Improved vesicles
CU23313A1 (es) 2002-11-27 2008-09-25 Inst Finlay Ct De Investigacia Mã0/00todo de obtenciã"n de estructuras cocleares. composiciones vacunales y adyuvantes basados en estructuras cocleares y sus intermediarios
GB0316560D0 (en) 2003-07-15 2003-08-20 Chiron Srl Vesicle filtration
JP5173194B2 (ja) * 2003-12-23 2013-03-27 グラクソスミスクライン バイオロジカルズ ソシエテ アノニム ワクチン
GB0419627D0 (en) 2004-09-03 2004-10-06 Chiron Srl Immunogenic bacterial vesicles with outer membrane proteins
GB0424092D0 (en) 2004-10-29 2004-12-01 Chiron Srl Immunogenic bacterial vesicles with outer membrane proteins
JP5275982B2 (ja) 2006-06-12 2013-08-28 グラクソスミスクライン バイオロジカルズ ソシエテ アノニム ワクチン
CA2702871A1 (en) 2007-10-19 2009-04-23 Novartis Ag Meningococcal vaccine formulations
EP3263591B1 (en) 2008-02-21 2019-03-27 GlaxoSmithKline Biologicals S.A. Meningococcal fhbp polypeptides
GB0822634D0 (en) 2008-12-11 2009-01-21 Novartis Ag Meningitis vaccines
US20100189737A1 (en) 2008-12-17 2010-07-29 Arico Beatrice Meningococcal vaccines including hemoglobin receptor
AU2010258677B2 (en) 2009-06-10 2016-10-06 Glaxosmithkline Biologicals S.A. Benzonaphthyridine-containing vaccines
EP2470204B1 (en) 2009-08-27 2015-12-16 GlaxoSmithKline Biologicals SA Hybrid polypeptides including meningococcal fhbp sequences
NZ598459A (en) 2009-08-27 2014-03-28 Novartis Ag Adjuvant comprising aluminium, oligonucleotide and polycation
JO3257B1 (ar) 2009-09-02 2018-09-16 Novartis Ag مركبات وتركيبات كمعدلات لفاعلية tlr
GB0917003D0 (en) 2009-09-28 2009-11-11 Novartis Vaccines Inst For Global Health Srl Purification of bacterial vesicles
EP2483390A2 (en) 2009-09-30 2012-08-08 Novartis AG Expression of meningococcal fhbp polypeptides
AU2010310985B2 (en) 2009-10-27 2014-11-06 Glaxosmithkline Biologicals S.A. Modified meningococcal fHBP polypeptides
WO2011057148A1 (en) 2009-11-05 2011-05-12 Irm Llc Compounds and compositions as tlr-7 activity modulators
SG181712A1 (en) 2009-12-15 2012-07-30 Novartis Ag Homogeneous suspension of immunopotentiating compounds and uses thereof
US9567377B2 (en) 2010-03-10 2017-02-14 Glaxosmithkline Biologicals Sa Immunogenic composition
JP2013522287A (ja) 2010-03-18 2013-06-13 ノバルティス アーゲー 血清群ｂ髄膜炎菌のためのアジュバント添加ワクチン
EA031379B1 (ru) 2010-03-23 2018-12-28 Новартис Аг Соединения (липопептиды на основе цистеина) и композиции в качестве агонистов tlr2, применяемые для лечения инфекционных, воспалительных, респираторных и других заболеваний
GB201015132D0 (en) 2010-09-10 2010-10-27 Univ Bristol Vaccine composition
BR112013005626B1 (pt) 2010-09-10 2022-07-26 Glaxosmithkline Biologicals Sa Meningococo, processo para a preparação de uma cepa meningocócica, vesículas de membrana externa, composição farmacêutica imunogênica, e, uso de uma composição
WO2012153302A1 (en) 2011-05-12 2012-11-15 Novartis Ag Antipyretics to enhance tolerability of vesicle-based vaccines
RU2014135522A (ru) 2012-02-02 2016-03-27 Новартис Аг Промоторы для увеличенной экспрессии белка у менингококка
EP2823312B1 (en) 2012-03-08 2019-08-07 GlaxoSmithKline Biologicals SA In vitro potency assay for protein-based meningococcal vaccines
JP2015521595A (ja) 2012-06-14 2015-07-30 ノバルティス アーゲー 血清群ｘ髄膜炎菌のためのワクチン
JP6324961B2 (ja) 2012-09-06 2018-05-16 ノバルティス アーゲー 血清群ｂ髄膜炎菌とｄ／ｔ／ｐとの組み合わせワクチン
AU2013320313B2 (en) 2012-09-18 2018-07-12 Glaxosmithkline Biologicals Sa Outer membrane vesicles
JP6786394B2 (ja) 2014-02-28 2020-11-18 グラクソスミスクライン バイオロジカルズ ソシエテ アノニム 改変髄膜炎菌ｆＨｂｐポリペプチド
WO2018042015A1 (en) 2016-09-02 2018-03-08 Glaxosmithkline Biologicals Sa Vaccines for neisseria gonorrhoeae
EP3607967A1 (en) 2018-08-09 2020-02-12 GlaxoSmithKline Biologicals S.A. Modified meningococcal fhbp polypeptides
CA3117867A1 (en) 2018-11-06 2020-05-14 Glaxosmithkline Biologicals Sa Immunogenic compositions
EP3799884A1 (en) 2019-10-01 2021-04-07 GlaxoSmithKline Biologicals S.A. Immunogenic compositions
GB202115077D0 (en) 2021-10-21 2021-12-08 Glaxosmithkline Biologicals Sa Assay
GB202115072D0 (en) 2021-10-21 2021-12-08 Glaxosmithkline Biologicals Sa Assay
GB202211033D0 (en) 2022-07-28 2022-09-14 Glaxosmithkline Biologicals Sa Purification process

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4317811A (en) 1980-09-11 1982-03-02 Merck & Co., Inc. Herpes simplex type 1 subunit vaccine
US12109243B2 (en) 2017-09-08 2024-10-08 Evelo Biosciences, Inc. Bacterial extracellular vesicles

Also Published As

Publication number Publication date
DK154841C (da) 1989-06-05
IL58673A0 (en) 1980-02-29
JPS6350332B2 (enExample) 1988-10-07
DK154841B (da) 1988-12-27
EP0011243A1 (de) 1980-05-28
JPS5566519A (en) 1980-05-20
AU533386B2 (en) 1983-11-24
DK475779A (da) 1980-05-12
CA1142083A (en) 1983-03-01
ES485715A1 (es) 1980-05-16
IL58673A (en) 1983-02-23
EP0011243B1 (de) 1982-04-14
DE2962526D1 (en) 1982-05-27
ATE857T1 (de) 1982-04-15
AU5268279A (en) 1980-05-15

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