DK154841C - Fremgangsmaade til fremstilling af membranproteiner ud fra neisseria meningitidis - Google Patents
Fremgangsmaade til fremstilling af membranproteiner ud fra neisseria meningitidisInfo
- Publication number
- DK154841C DK154841C DK475779A DK475779A DK154841C DK 154841 C DK154841 C DK 154841C DK 475779 A DK475779 A DK 475779A DK 475779 A DK475779 A DK 475779A DK 154841 C DK154841 C DK 154841C
- Authority
- DK
- Denmark
- Prior art keywords
- membrane proteins
- neisseria meningitidis
- procedure
- manufacturing membrane
- optionally
- Prior art date
Links
- 108010052285 Membrane Proteins Proteins 0.000 title abstract 2
- 241000588650 Neisseria meningitidis Species 0.000 title abstract 2
- 238000000034 method Methods 0.000 title abstract 2
- 238000004519 manufacturing process Methods 0.000 title 1
- 238000013019 agitation Methods 0.000 abstract 1
- 239000007864 aqueous solution Substances 0.000 abstract 1
- 230000001580 bacterial effect Effects 0.000 abstract 1
- 239000003599 detergent Substances 0.000 abstract 1
- 238000002955 isolation Methods 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
- 238000000746 purification Methods 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/02—Bacterial antigens
- A61K39/095—Neisseria
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Epidemiology (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Microbiology (AREA)
- Mycology (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical & Material Sciences (AREA)
- Immunology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Peptides Or Proteins (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE2848965 | 1978-11-11 | ||
| DE19782848965 DE2848965A1 (de) | 1978-11-11 | 1978-11-11 | Verfahren zur herstellung von membranproteinen aus neisseria meningitidis und diese enthaltende vaccine |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| DK475779A DK475779A (da) | 1980-05-12 |
| DK154841B DK154841B (da) | 1988-12-27 |
| DK154841C true DK154841C (da) | 1989-06-05 |
Family
ID=6054405
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK475779A DK154841C (da) | 1978-11-11 | 1979-11-09 | Fremgangsmaade til fremstilling af membranproteiner ud fra neisseria meningitidis |
Country Status (9)
| Country | Link |
|---|---|
| EP (1) | EP0011243B1 (da) |
| JP (1) | JPS5566519A (da) |
| AT (1) | ATE857T1 (da) |
| AU (1) | AU533386B2 (da) |
| CA (1) | CA1142083A (da) |
| DE (2) | DE2848965A1 (da) |
| DK (1) | DK154841C (da) |
| ES (1) | ES485715A1 (da) |
| IL (1) | IL58673A (da) |
Families Citing this family (50)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4317811A (en) | 1980-09-11 | 1982-03-02 | Merck & Co., Inc. | Herpes simplex type 1 subunit vaccine |
| WO1984002194A1 (en) * | 1982-12-02 | 1984-06-07 | Univ Rockefeller | IgA BINDING ANTIBODY |
| US7118757B1 (en) | 1988-12-19 | 2006-10-10 | Wyeth Holdings Corporation | Meningococcal class 1 outer-membrane protein vaccine |
| ATE346609T1 (de) | 1998-05-29 | 2006-12-15 | Novartis Vaccines & Diagnostic | Kombinierte meningitis b/c impfstoffe |
| EP2258851A1 (en) | 1999-05-19 | 2010-12-08 | Novartis Vaccines and Diagnostics S.r.l. | Combination neisserial compositions |
| GB9918319D0 (en) | 1999-08-03 | 1999-10-06 | Smithkline Beecham Biolog | Vaccine composition |
| GB9928196D0 (en) | 1999-11-29 | 2000-01-26 | Chiron Spa | Combinations of B, C and other antigens |
| ATE476988T1 (de) | 2000-01-17 | 2010-08-15 | Novartis Vaccines & Diagnostic | Membranvesikel (omv) impfstoff, der n. meningitidis serogruppe b membranproteine enthält |
| GB0103171D0 (en) * | 2001-02-08 | 2001-03-28 | Smithkline Beecham Biolog | Vaccine composition |
| NZ587398A (en) | 2002-08-02 | 2012-03-30 | Glaxosmithkline Biolog Sa | Neisserial bleb preparations and vaccines comprising them |
| GB0220194D0 (en) | 2002-08-30 | 2002-10-09 | Chiron Spa | Improved vesicles |
| CU23313A1 (es) | 2002-11-27 | 2008-09-25 | Inst Finlay Ct De Investigacia | Mã0/00todo de obtenciã"n de estructuras cocleares. composiciones vacunales y adyuvantes basados en estructuras cocleares y sus intermediarios |
| GB0316560D0 (en) | 2003-07-15 | 2003-08-20 | Chiron Srl | Vesicle filtration |
| CA2550927A1 (en) * | 2003-12-23 | 2005-07-14 | Glaxosmithkline Biologicals S.A. | A gram negative bacterium with reduced lps level in the outer membrane and use thereof for treating gram negative bacterial infection |
| GB0419627D0 (en) | 2004-09-03 | 2004-10-06 | Chiron Srl | Immunogenic bacterial vesicles with outer membrane proteins |
| GB0424092D0 (en) | 2004-10-29 | 2004-12-01 | Chiron Srl | Immunogenic bacterial vesicles with outer membrane proteins |
| JP5275983B2 (ja) | 2006-06-12 | 2013-08-28 | グラクソスミスクライン バイオロジカルズ ソシエテ アノニム | ワクチン |
| SI2200642T1 (sl) | 2007-10-19 | 2012-06-29 | Novartis Ag | Formulacije meningokoknega cepiva |
| NZ587382A (en) | 2008-02-21 | 2012-01-12 | Novartis Ag | Meningococcal fhbp polypeptides |
| GB0822634D0 (en) | 2008-12-11 | 2009-01-21 | Novartis Ag | Meningitis vaccines |
| CN102300585A (zh) | 2008-12-17 | 2011-12-28 | 诺华有限公司 | 包含血红蛋白受体的脑膜炎球菌疫苗 |
| CN102762226A (zh) | 2009-06-10 | 2012-10-31 | 诺华有限公司 | 含苯并萘啶的疫苗 |
| AU2010288240B2 (en) | 2009-08-27 | 2014-03-27 | Novartis Ag | Hybrid polypeptides including meningococcal fHBP sequences |
| CN102740882A (zh) | 2009-08-27 | 2012-10-17 | 诺华有限公司 | 含有铝、寡核苷酸和聚阳离子的佐剂 |
| TWI445708B (zh) | 2009-09-02 | 2014-07-21 | Irm Llc | 作為tlr活性調節劑之化合物及組合物 |
| GB0917003D0 (en) | 2009-09-28 | 2009-11-11 | Novartis Vaccines Inst For Global Health Srl | Purification of bacterial vesicles |
| EP2483390A2 (en) | 2009-09-30 | 2012-08-08 | Novartis AG | Expression of meningococcal fhbp polypeptides |
| CA2779816A1 (en) | 2009-10-27 | 2011-05-05 | Novartis Ag | Modified meningococcal fhbp polypeptides |
| WO2011057148A1 (en) | 2009-11-05 | 2011-05-12 | Irm Llc | Compounds and compositions as tlr-7 activity modulators |
| BR112012014624A8 (pt) | 2009-12-15 | 2017-12-26 | Novartis Ag | suspensão homogênea de compostos de imunopotenciação e usos dos destes |
| WO2011110635A1 (en) | 2010-03-10 | 2011-09-15 | Glaxosmithkline Biologicals S.A. | Immunogenic composition |
| US20130071422A1 (en) | 2010-03-18 | 2013-03-21 | Michele Pallaoro | Adjuvanted vaccines for serogroup b meningococcus |
| US8808703B2 (en) | 2010-03-23 | 2014-08-19 | Tom Yao-Hsiang Wu | Compounds (cystein based lipopeptides) and compositions as TLR2 agonists used for treating infections, inflammations, respiratory diseases etc |
| GB201015132D0 (en) | 2010-09-10 | 2010-10-27 | Univ Bristol | Vaccine composition |
| BR112013005626B1 (pt) | 2010-09-10 | 2022-07-26 | Glaxosmithkline Biologicals Sa | Meningococo, processo para a preparação de uma cepa meningocócica, vesículas de membrana externa, composição farmacêutica imunogênica, e, uso de uma composição |
| US20150147356A1 (en) | 2011-05-12 | 2015-05-28 | Alan Kimura | Antipyretics to enhance tolerability of vesicle-based vaccines |
| MX2014008988A (es) | 2012-02-02 | 2014-08-27 | Novartis Ag | Promotores para aumento de expresion de proteinas en meningococo. |
| ES2750366T3 (es) | 2012-03-08 | 2020-03-25 | Glaxosmithkline Biologicals Sa | Ensayo de potencia in vitro para vacunas meningocócicas basadas en proteína |
| NZ630133A (en) | 2012-06-14 | 2016-10-28 | Novartis Ag | Vaccines for serogroup x meningococcus |
| US9526776B2 (en) | 2012-09-06 | 2016-12-27 | Glaxosmithkline Biologicals Sa | Combination vaccines with serogroup B meningococcus and D/T/P |
| MX363529B (es) | 2012-09-18 | 2019-03-27 | Novartis Ag | Vesículas de membrana externa. |
| JP6786394B2 (ja) | 2014-02-28 | 2020-11-18 | グラクソスミスクライン バイオロジカルズ ソシエテ アノニム | 改変髄膜炎菌fHbpポリペプチド |
| EP3506933A2 (en) | 2016-09-02 | 2019-07-10 | GlaxoSmithKline Biologicals SA | Vaccines for neisseria gonorrhoeae |
| EP3678693A1 (en) | 2017-09-08 | 2020-07-15 | Evelo Biosciences, Inc. | Bacterial extracellular vesicles |
| EP3607967A1 (en) | 2018-08-09 | 2020-02-12 | GlaxoSmithKline Biologicals S.A. | Modified meningococcal fhbp polypeptides |
| CN112996538B (zh) | 2018-11-06 | 2025-07-08 | 葛兰素史密丝克莱恩生物有限公司 | 免疫原性组合物 |
| EP3799884A1 (en) | 2019-10-01 | 2021-04-07 | GlaxoSmithKline Biologicals S.A. | Immunogenic compositions |
| GB202115077D0 (en) | 2021-10-21 | 2021-12-08 | Glaxosmithkline Biologicals Sa | Assay |
| GB202115072D0 (en) | 2021-10-21 | 2021-12-08 | Glaxosmithkline Biologicals Sa | Assay |
| GB202211033D0 (en) | 2022-07-28 | 2022-09-14 | Glaxosmithkline Biologicals Sa | Purification process |
-
1978
- 1978-11-11 DE DE19782848965 patent/DE2848965A1/de not_active Withdrawn
-
1979
- 1979-11-06 ES ES485715A patent/ES485715A1/es not_active Expired
- 1979-11-08 EP EP79104391A patent/EP0011243B1/de not_active Expired
- 1979-11-08 AT AT79104391T patent/ATE857T1/de not_active IP Right Cessation
- 1979-11-08 DE DE7979104391T patent/DE2962526D1/de not_active Expired
- 1979-11-09 AU AU52682/79A patent/AU533386B2/en not_active Ceased
- 1979-11-09 JP JP14456179A patent/JPS5566519A/ja active Granted
- 1979-11-09 DK DK475779A patent/DK154841C/da not_active IP Right Cessation
- 1979-11-09 CA CA000339541A patent/CA1142083A/en not_active Expired
- 1979-11-09 IL IL58673A patent/IL58673A/xx unknown
Also Published As
| Publication number | Publication date |
|---|---|
| AU533386B2 (en) | 1983-11-24 |
| DK475779A (da) | 1980-05-12 |
| DE2848965A1 (de) | 1980-05-22 |
| JPS5566519A (en) | 1980-05-20 |
| JPS6350332B2 (da) | 1988-10-07 |
| DK154841B (da) | 1988-12-27 |
| CA1142083A (en) | 1983-03-01 |
| EP0011243B1 (de) | 1982-04-14 |
| IL58673A0 (en) | 1980-02-29 |
| IL58673A (en) | 1983-02-23 |
| DE2962526D1 (en) | 1982-05-27 |
| EP0011243A1 (de) | 1980-05-28 |
| AU5268279A (en) | 1980-05-15 |
| ATE857T1 (de) | 1982-04-15 |
| ES485715A1 (es) | 1980-05-16 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PBP | Patent lapsed |