ATE857T1 - Verfahren zur herstellung von membranproteinen aus neisseria meningitidis und diese enthaltende vaccine. - Google Patents
Verfahren zur herstellung von membranproteinen aus neisseria meningitidis und diese enthaltende vaccine.Info
- Publication number
- ATE857T1 ATE857T1 AT79104391T AT79104391T ATE857T1 AT E857 T1 ATE857 T1 AT E857T1 AT 79104391 T AT79104391 T AT 79104391T AT 79104391 T AT79104391 T AT 79104391T AT E857 T1 ATE857 T1 AT E857T1
- Authority
- AT
- Austria
- Prior art keywords
- membrane proteins
- neisseria meningitidis
- production
- vaccine containing
- optionally
- Prior art date
Links
- 108010052285 Membrane Proteins Proteins 0.000 title abstract 2
- 241000588650 Neisseria meningitidis Species 0.000 title abstract 2
- 238000000034 method Methods 0.000 title abstract 2
- 229960005486 vaccine Drugs 0.000 title 1
- 238000013019 agitation Methods 0.000 abstract 1
- 239000007864 aqueous solution Substances 0.000 abstract 1
- 230000001580 bacterial effect Effects 0.000 abstract 1
- 239000003599 detergent Substances 0.000 abstract 1
- 238000002955 isolation Methods 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
- 238000000746 purification Methods 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/02—Bacterial antigens
- A61K39/095—Neisseria
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Immunology (AREA)
- Medicinal Chemistry (AREA)
- Microbiology (AREA)
- Mycology (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Peptides Or Proteins (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE19782848965 DE2848965A1 (de) | 1978-11-11 | 1978-11-11 | Verfahren zur herstellung von membranproteinen aus neisseria meningitidis und diese enthaltende vaccine |
| EP79104391A EP0011243B1 (de) | 1978-11-11 | 1979-11-08 | Verfahren zur Herstellung von Membranproteinen aus Neisseria meningitidis und diese enthaltende Vaccine |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE857T1 true ATE857T1 (de) | 1982-04-15 |
Family
ID=6054405
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT79104391T ATE857T1 (de) | 1978-11-11 | 1979-11-08 | Verfahren zur herstellung von membranproteinen aus neisseria meningitidis und diese enthaltende vaccine. |
Country Status (9)
| Country | Link |
|---|---|
| EP (1) | EP0011243B1 (de) |
| JP (1) | JPS5566519A (de) |
| AT (1) | ATE857T1 (de) |
| AU (1) | AU533386B2 (de) |
| CA (1) | CA1142083A (de) |
| DE (2) | DE2848965A1 (de) |
| DK (1) | DK154841C (de) |
| ES (1) | ES485715A1 (de) |
| IL (1) | IL58673A (de) |
Families Citing this family (50)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4317811A (en) | 1980-09-11 | 1982-03-02 | Merck & Co., Inc. | Herpes simplex type 1 subunit vaccine |
| EP0127681B1 (de) * | 1982-12-02 | 1993-03-03 | The Rockefeller University | Ig-A BINDENDES PROTEIN |
| US7118757B1 (en) | 1988-12-19 | 2006-10-10 | Wyeth Holdings Corporation | Meningococcal class 1 outer-membrane protein vaccine |
| JP5074644B2 (ja) | 1998-05-29 | 2012-11-14 | ノバルティス バクシンズ アンド ダイアグノスティックス，インコーポレーテッド | 組合わせの髄膜炎菌ｂ／ｃワクチン |
| AU783894B2 (en) | 1999-05-19 | 2005-12-22 | Novartis Vaccines And Diagnostics S.R.L. | Combination neisserial compositions |
| GB9918319D0 (en) | 1999-08-03 | 1999-10-06 | Smithkline Beecham Biolog | Vaccine composition |
| GB9928196D0 (en) | 1999-11-29 | 2000-01-26 | Chiron Spa | Combinations of B, C and other antigens |
| CA2871789C (en) | 2000-01-17 | 2017-04-04 | Novartis Vaccines And Diagnostics S.R.L. | Outer membrane vesicle (omv) vaccine comprising n. meningitidis serogroup b outer membrane proteins |
| GB0103171D0 (en) * | 2001-02-08 | 2001-03-28 | Smithkline Beecham Biolog | Vaccine composition |
| CA2493124C (en) | 2002-08-02 | 2014-04-29 | Glaxosmithkline Biologicals S.A. | Vaccine |
| GB0220194D0 (en) | 2002-08-30 | 2002-10-09 | Chiron Spa | Improved vesicles |
| CU23313A1 (es) | 2002-11-27 | 2008-09-25 | Inst Finlay Ct De Investigacia | Mã0/00todo de obtenciã"n de estructuras cocleares. composiciones vacunales y adyuvantes basados en estructuras cocleares y sus intermediarios |
| GB0316560D0 (en) | 2003-07-15 | 2003-08-20 | Chiron Srl | Vesicle filtration |
| JP5173194B2 (ja) * | 2003-12-23 | 2013-03-27 | グラクソスミスクライン バイオロジカルズ ソシエテ アノニム | ワクチン |
| GB0419627D0 (en) | 2004-09-03 | 2004-10-06 | Chiron Srl | Immunogenic bacterial vesicles with outer membrane proteins |
| GB0424092D0 (en) | 2004-10-29 | 2004-12-01 | Chiron Srl | Immunogenic bacterial vesicles with outer membrane proteins |
| DE602007003596D1 (de) | 2006-06-12 | 2010-01-14 | Glaxosmithkline Biolog Sa | Impfstoff |
| BR122016015627A2 (pt) | 2007-10-19 | 2018-10-30 | Novartis Ag | kit, composição antigênica liofilizada e método para preparação de uma composição imunogênica |
| EP2886551A3 (de) | 2008-02-21 | 2015-09-23 | Novartis AG | Meningokokken-FHBP-Polypeptide |
| GB0822634D0 (en) | 2008-12-11 | 2009-01-21 | Novartis Ag | Meningitis vaccines |
| WO2010070453A2 (en) | 2008-12-17 | 2010-06-24 | Novartis Ag | Meningococcal vaccines including hemoglobin receptor |
| CA2765112A1 (en) | 2009-06-10 | 2010-12-16 | Novartis Ag | Benzonaphthyridine-containing vaccines |
| JP2013502918A (ja) | 2009-08-27 | 2013-01-31 | ノバルティス アーゲー | 髄膜炎菌ｆＨＢＰ配列を含むハイブリッドポリペプチド |
| US8858958B2 (en) | 2009-08-27 | 2014-10-14 | Novartis Ag | Adjuvant comprising aluminum, oligonucleotide and polycation |
| JO3257B1 (ar) | 2009-09-02 | 2018-09-16 | Novartis Ag | مركبات وتركيبات كمعدلات لفاعلية tlr |
| GB0917003D0 (en) | 2009-09-28 | 2009-11-11 | Novartis Vaccines Inst For Global Health Srl | Purification of bacterial vesicles |
| US20130022639A1 (en) | 2009-09-30 | 2013-01-24 | Novartis Ag | Expression of meningococcal fhbp polypeptides |
| BR112012010531A2 (pt) | 2009-10-27 | 2019-09-24 | Novartis Ag | "polipeptídeos de modificação meningocócica fhbp" |
| WO2011057148A1 (en) | 2009-11-05 | 2011-05-12 | Irm Llc | Compounds and compositions as tlr-7 activity modulators |
| US9408907B2 (en) | 2009-12-15 | 2016-08-09 | Glaxosmithkline Biologicals Sa | Homogenous suspension of immunopotentiating compounds and uses thereof |
| EP2544714A1 (de) | 2010-03-10 | 2013-01-16 | GlaxoSmithKline Biologicals S.A. | Impfstoffzusammensetzung |
| WO2012020326A1 (en) | 2010-03-18 | 2012-02-16 | Novartis Ag | Adjuvanted vaccines for serogroup b meningococcus |
| AU2011232421B2 (en) | 2010-03-23 | 2015-08-13 | Novartis Ag | Compounds (cystein based lipopeptides) and compositions as TLR2 agonists used for treating infections, inflammations, respiratory diseases etc. |
| BR112013005626B1 (pt) | 2010-09-10 | 2022-07-26 | Glaxosmithkline Biologicals Sa | Meningococo, processo para a preparação de uma cepa meningocócica, vesículas de membrana externa, composição farmacêutica imunogênica, e, uso de uma composição |
| GB201015132D0 (en) | 2010-09-10 | 2010-10-27 | Univ Bristol | Vaccine composition |
| US20150147356A1 (en) | 2011-05-12 | 2015-05-28 | Alan Kimura | Antipyretics to enhance tolerability of vesicle-based vaccines |
| MX2014008988A (es) | 2012-02-02 | 2014-08-27 | Novartis Ag | Promotores para aumento de expresion de proteinas en meningococo. |
| ES2750366T3 (es) | 2012-03-08 | 2020-03-25 | Glaxosmithkline Biologicals Sa | Ensayo de potencia in vitro para vacunas meningocócicas basadas en proteína |
| MX357538B (es) | 2012-06-14 | 2018-07-13 | Novartis Ag | Vacunas para meningococo de serogrupo x. |
| EP2892553A1 (de) | 2012-09-06 | 2015-07-15 | Novartis AG | Kombinationsvakzine mit serogruppe-b-meningokokken und d/t/p |
| RU2662970C2 (ru) | 2012-09-18 | 2018-07-31 | Новартис Аг | Везикулы наружной мембраны |
| CA2940447C (en) | 2014-02-28 | 2023-07-11 | Glaxosmithkline Biologicals Sa | Modified meningococcal fhbp polypeptides |
| WO2018042015A1 (en) | 2016-09-02 | 2018-03-08 | Glaxosmithkline Biologicals Sa | Vaccines for neisseria gonorrhoeae |
| CN111148531A (zh) | 2017-09-08 | 2020-05-12 | 伊夫罗生物科学公司 | 细菌胞外囊泡 |
| EP3607967A1 (de) | 2018-08-09 | 2020-02-12 | GlaxoSmithKline Biologicals S.A. | Modifizierte meningokokken fhbp polypeptide |
| US12128094B2 (en) | 2018-11-06 | 2024-10-29 | Glaxosmithkline Biologicals Sa | Immunogenic compositions comprising OMVs, an acellular pertussis antigen, a tetanus toxoid and a diphtheria toxoid |
| EP3799884A1 (de) | 2019-10-01 | 2021-04-07 | GlaxoSmithKline Biologicals S.A. | Immunogene zusammensetzungen |
| GB202115077D0 (en) | 2021-10-21 | 2021-12-08 | Glaxosmithkline Biologicals Sa | Assay |
| GB202115072D0 (en) | 2021-10-21 | 2021-12-08 | Glaxosmithkline Biologicals Sa | Assay |
| GB202211033D0 (en) | 2022-07-28 | 2022-09-14 | Glaxosmithkline Biologicals Sa | Purification process |
-
1978
- 1978-11-11 DE DE19782848965 patent/DE2848965A1/de not_active Withdrawn
-
1979
- 1979-11-06 ES ES485715A patent/ES485715A1/es not_active Expired
- 1979-11-08 DE DE7979104391T patent/DE2962526D1/de not_active Expired
- 1979-11-08 AT AT79104391T patent/ATE857T1/de not_active IP Right Cessation
- 1979-11-08 EP EP79104391A patent/EP0011243B1/de not_active Expired
- 1979-11-09 CA CA000339541A patent/CA1142083A/en not_active Expired
- 1979-11-09 JP JP14456179A patent/JPS5566519A/ja active Granted
- 1979-11-09 AU AU52682/79A patent/AU533386B2/en not_active Ceased
- 1979-11-09 DK DK475779A patent/DK154841C/da not_active IP Right Cessation
- 1979-11-09 IL IL58673A patent/IL58673A/xx unknown
Also Published As
| Publication number | Publication date |
|---|---|
| DK154841C (da) | 1989-06-05 |
| EP0011243B1 (de) | 1982-04-14 |
| JPS5566519A (en) | 1980-05-20 |
| AU5268279A (en) | 1980-05-15 |
| CA1142083A (en) | 1983-03-01 |
| IL58673A0 (en) | 1980-02-29 |
| EP0011243A1 (de) | 1980-05-28 |
| DK154841B (da) | 1988-12-27 |
| DE2848965A1 (de) | 1980-05-22 |
| ES485715A1 (es) | 1980-05-16 |
| AU533386B2 (en) | 1983-11-24 |
| IL58673A (en) | 1983-02-23 |
| DE2962526D1 (en) | 1982-05-27 |
| JPS6350332B2 (de) | 1988-10-07 |
| DK475779A (da) | 1980-05-12 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| EEIH | Change in the person of patent owner | ||
| EELA | Cancelled due to lapse of time |