IL58673A - Process for the isolation of membrane proteins from neisseria meningitidis and vaccines containing same - Google Patents
Process for the isolation of membrane proteins from neisseria meningitidis and vaccines containing sameInfo
- Publication number
- IL58673A IL58673A IL58673A IL5867379A IL58673A IL 58673 A IL58673 A IL 58673A IL 58673 A IL58673 A IL 58673A IL 5867379 A IL5867379 A IL 5867379A IL 58673 A IL58673 A IL 58673A
- Authority
- IL
- Israel
- Prior art keywords
- isolation
- membrane proteins
- neisseria meningitidis
- containing same
- vaccines containing
- Prior art date
Links
- 108010052285 Membrane Proteins Proteins 0.000 title abstract 2
- 241000588650 Neisseria meningitidis Species 0.000 title abstract 2
- 238000002955 isolation Methods 0.000 title abstract 2
- 238000000034 method Methods 0.000 title abstract 2
- 229960005486 vaccine Drugs 0.000 title 1
- 238000013019 agitation Methods 0.000 abstract 1
- 239000007864 aqueous solution Substances 0.000 abstract 1
- 230000001580 bacterial effect Effects 0.000 abstract 1
- 239000003599 detergent Substances 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
- 238000000746 purification Methods 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/02—Bacterial antigens
- A61K39/095—Neisseria
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Epidemiology (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Microbiology (AREA)
- Mycology (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical & Material Sciences (AREA)
- Immunology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Peptides Or Proteins (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Abstract
1. Process for the isolation of membrane proteins from Neisseria meningitidis which comprises treating the organism with the aqueous solution of a detergent in a concentration of 0.1 to 2% w/v for 15 minutes to 24 hours, allowing the mixture to stand, optionally with agitation, separating the extract from the bacterial residue and optionally carrying out a further purification.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE19782848965 DE2848965A1 (en) | 1978-11-11 | 1978-11-11 | METHOD FOR PRODUCING MEMBRANE PROTEINS FROM NEISSERIA MENINGITIDIS AND VACCINE CONTAINING THEM |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| IL58673A0 IL58673A0 (en) | 1980-02-29 |
| IL58673A true IL58673A (en) | 1983-02-23 |
Family
ID=6054405
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IL58673A IL58673A (en) | 1978-11-11 | 1979-11-09 | Process for the isolation of membrane proteins from neisseria meningitidis and vaccines containing same |
Country Status (9)
| Country | Link |
|---|---|
| EP (1) | EP0011243B1 (en) |
| JP (1) | JPS5566519A (en) |
| AT (1) | ATE857T1 (en) |
| AU (1) | AU533386B2 (en) |
| CA (1) | CA1142083A (en) |
| DE (2) | DE2848965A1 (en) |
| DK (1) | DK154841C (en) |
| ES (1) | ES485715A1 (en) |
| IL (1) | IL58673A (en) |
Families Citing this family (50)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4317811A (en) | 1980-09-11 | 1982-03-02 | Merck & Co., Inc. | Herpes simplex type 1 subunit vaccine |
| CA1221626A (en) * | 1982-12-02 | 1987-05-12 | Milan Blake | Iga binding protein |
| US7118757B1 (en) | 1988-12-19 | 2006-10-10 | Wyeth Holdings Corporation | Meningococcal class 1 outer-membrane protein vaccine |
| ES2278446T3 (en) | 1998-05-29 | 2007-08-01 | Novartis Vaccines And Diagnostics, Inc. | B / C COMBINED VACCINES AGAINST MENINGITIS. |
| BR0010721A (en) | 1999-05-19 | 2002-06-11 | Chiron Spa | Compositions of combined neisseries |
| GB9918319D0 (en) | 1999-08-03 | 1999-10-06 | Smithkline Beecham Biolog | Vaccine composition |
| GB9928196D0 (en) | 1999-11-29 | 2000-01-26 | Chiron Spa | Combinations of B, C and other antigens |
| CA2871789C (en) | 2000-01-17 | 2017-04-04 | Novartis Vaccines And Diagnostics S.R.L. | Outer membrane vesicle (omv) vaccine comprising n. meningitidis serogroup b outer membrane proteins |
| GB0103171D0 (en) * | 2001-02-08 | 2001-03-28 | Smithkline Beecham Biolog | Vaccine composition |
| DE20321889U1 (en) * | 2002-08-02 | 2012-03-12 | Glaxosmithkline Biologicals S.A. | vaccine composition |
| GB0220194D0 (en) | 2002-08-30 | 2002-10-09 | Chiron Spa | Improved vesicles |
| CU23313A1 (en) | 2002-11-27 | 2008-09-25 | Inst Finlay Ct De Investigacia | MÃ0 / 00 METHOD OF OBTAINING COCLEAR STRUCTURES VACCINAL COMPOSITIONS AND ADJUSTS BASED ON COCLEAR STRUCTURES AND THEIR INTERMEDIARIES |
| GB0316560D0 (en) | 2003-07-15 | 2003-08-20 | Chiron Srl | Vesicle filtration |
| JP5173194B2 (en) * | 2003-12-23 | 2013-03-27 | グラクソスミスクライン バイオロジカルズ ソシエテ アノニム | vaccine |
| GB0419627D0 (en) | 2004-09-03 | 2004-10-06 | Chiron Srl | Immunogenic bacterial vesicles with outer membrane proteins |
| GB0424092D0 (en) | 2004-10-29 | 2004-12-01 | Chiron Srl | Immunogenic bacterial vesicles with outer membrane proteins |
| EP2032161B1 (en) | 2006-06-12 | 2012-07-11 | GlaxoSmithKline Biologicals S.A. | L3v los vaccines |
| BRPI0818545A2 (en) | 2007-10-19 | 2017-07-04 | Novartis Ag | meningococcal vaccine formulations |
| WO2009104097A2 (en) | 2008-02-21 | 2009-08-27 | Novartis Ag | Meningococcal fhbp polypeptides |
| GB0822634D0 (en) | 2008-12-11 | 2009-01-21 | Novartis Ag | Meningitis vaccines |
| EP2367568A2 (en) | 2008-12-17 | 2011-09-28 | Novartis AG | Meningococcal vaccines including hemoglobin receptor |
| WO2010144734A1 (en) | 2009-06-10 | 2010-12-16 | Novartis Ag | Benzonaphthyridine-containing vaccines |
| CN102596240B (en) | 2009-08-27 | 2015-02-04 | 诺华股份有限公司 | Hybrid polypeptides including meningococcal fHBP sequences |
| WO2011024071A1 (en) | 2009-08-27 | 2011-03-03 | Novartis Ag | Adjuvant comprising aluminium, oligonucleotide and polycation |
| TWI445708B (en) | 2009-09-02 | 2014-07-21 | Irm Llc | Compounds and compositions as regulators of TLR activity |
| GB0917003D0 (en) | 2009-09-28 | 2009-11-11 | Novartis Vaccines Inst For Global Health Srl | Purification of bacterial vesicles |
| AU2010302344A1 (en) | 2009-09-30 | 2012-04-26 | Novartis Ag | Expression of meningococcal fhbp polypeptides |
| US20130022633A1 (en) | 2009-10-27 | 2013-01-24 | University Of Florence | MENINGOCOCCAL fHBP POLYPEPTIDES |
| WO2011057148A1 (en) | 2009-11-05 | 2011-05-12 | Irm Llc | Compounds and compositions as tlr-7 activity modulators |
| AU2010339921B2 (en) | 2009-12-15 | 2016-08-11 | Glaxosmithkline Biologicals S.A. | Homogeneous suspension of immunopotentiating compounds and uses thereof |
| JP2013521326A (en) | 2010-03-10 | 2013-06-10 | グラクソスミスクライン バイオロジカルズ ソシエテ アノニム | Immunogenic composition |
| AU2011288203A1 (en) | 2010-03-18 | 2012-08-23 | Novartis Ag | Adjuvanted vaccines for serogroup B meningococcus |
| AU2011232421B2 (en) | 2010-03-23 | 2015-08-13 | Novartis Ag | Compounds (cystein based lipopeptides) and compositions as TLR2 agonists used for treating infections, inflammations, respiratory diseases etc. |
| GB201015132D0 (en) | 2010-09-10 | 2010-10-27 | Univ Bristol | Vaccine composition |
| ES2759484T3 (en) | 2010-09-10 | 2020-05-11 | Glaxosmithkline Biologicals Sa | Meningococcus that overexpresses NadA and / or NHBA and external membrane vesicles derived from it |
| EP2707009A1 (en) | 2011-05-12 | 2014-03-19 | Novartis AG | Antipyretics to enhance tolerability of vesicle-based vaccines |
| BR112014019166A2 (en) | 2012-02-02 | 2017-07-04 | Novartis Ag | promoters for increased protein expression in meningococci |
| EP2823312B1 (en) | 2012-03-08 | 2019-08-07 | GlaxoSmithKline Biologicals SA | In vitro potency assay for protein-based meningococcal vaccines |
| WO2013186753A1 (en) | 2012-06-14 | 2013-12-19 | Novartis Ag | Vaccines for serogroup x meningococcus |
| BR112015005056A2 (en) | 2012-09-06 | 2017-11-21 | Novartis Ag | combination vaccines with meningococcus serogroup b and d / t / p |
| EP4056198A3 (en) | 2012-09-18 | 2022-12-07 | GlaxoSmithKline Biologicals SA | Outer membrane vesicles |
| AU2015222121B2 (en) | 2014-02-28 | 2018-01-18 | Glaxosmithkline Biologicals Sa | Modified meningococcal fHbp polypeptides |
| CA3035320A1 (en) | 2016-09-02 | 2018-03-08 | Glaxosmithkline Biologicals Sa | Vaccines for neisseria gonorrhoeae |
| MX2020002659A (en) | 2017-09-08 | 2020-09-09 | Evelo Biosciences Inc | Bacterial extracellular vesicles. |
| EP3607967A1 (en) | 2018-08-09 | 2020-02-12 | GlaxoSmithKline Biologicals S.A. | Modified meningococcal fhbp polypeptides |
| SG11202103389WA (en) | 2018-11-06 | 2021-05-28 | Glaxosmithkline Biologicals Sa | Immunogenic compositions |
| EP3799884A1 (en) | 2019-10-01 | 2021-04-07 | GlaxoSmithKline Biologicals S.A. | Immunogenic compositions |
| GB202115072D0 (en) | 2021-10-21 | 2021-12-08 | Glaxosmithkline Biologicals Sa | Assay |
| GB202115077D0 (en) | 2021-10-21 | 2021-12-08 | Glaxosmithkline Biologicals Sa | Assay |
| GB202211033D0 (en) | 2022-07-28 | 2022-09-14 | Glaxosmithkline Biologicals Sa | Purification process |
-
1978
- 1978-11-11 DE DE19782848965 patent/DE2848965A1/en not_active Withdrawn
-
1979
- 1979-11-06 ES ES485715A patent/ES485715A1/en not_active Expired
- 1979-11-08 DE DE7979104391T patent/DE2962526D1/en not_active Expired
- 1979-11-08 AT AT79104391T patent/ATE857T1/en not_active IP Right Cessation
- 1979-11-08 EP EP79104391A patent/EP0011243B1/en not_active Expired
- 1979-11-09 IL IL58673A patent/IL58673A/en unknown
- 1979-11-09 JP JP14456179A patent/JPS5566519A/en active Granted
- 1979-11-09 AU AU52682/79A patent/AU533386B2/en not_active Ceased
- 1979-11-09 CA CA000339541A patent/CA1142083A/en not_active Expired
- 1979-11-09 DK DK475779A patent/DK154841C/en not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| AU533386B2 (en) | 1983-11-24 |
| DK154841C (en) | 1989-06-05 |
| AU5268279A (en) | 1980-05-15 |
| IL58673A0 (en) | 1980-02-29 |
| DE2962526D1 (en) | 1982-05-27 |
| ATE857T1 (en) | 1982-04-15 |
| EP0011243A1 (en) | 1980-05-28 |
| JPS5566519A (en) | 1980-05-20 |
| DE2848965A1 (en) | 1980-05-22 |
| DK154841B (en) | 1988-12-27 |
| JPS6350332B2 (en) | 1988-10-07 |
| EP0011243B1 (en) | 1982-04-14 |
| DK475779A (en) | 1980-05-12 |
| ES485715A1 (en) | 1980-05-16 |
| CA1142083A (en) | 1983-03-01 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| HP | Change in proprietorship | ||
| KB | Patent renewed |