DK475779A - PROCEDURE FOR MANUFACTURING MEMBRANE PROTEINS FROM NEISSERIA MENINGITIDIS AND VACCINE CONTAINING SUCH MEMBRANE PROTEINS - Google Patents

PROCEDURE FOR MANUFACTURING MEMBRANE PROTEINS FROM NEISSERIA MENINGITIDIS AND VACCINE CONTAINING SUCH MEMBRANE PROTEINS

Info

Publication number
DK475779A
DK475779A DK475779A DK475779A DK475779A DK 475779 A DK475779 A DK 475779A DK 475779 A DK475779 A DK 475779A DK 475779 A DK475779 A DK 475779A DK 475779 A DK475779 A DK 475779A
Authority
DK
Denmark
Prior art keywords
membrane proteins
neisseria meningitidis
procedure
vaccine containing
manufacturing
Prior art date
Application number
DK475779A
Other languages
Danish (da)
Other versions
DK154841C (en
DK154841B (en
Inventor
T B Helting
G Guthoehrlein
Original Assignee
Behringwerke Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Behringwerke Ag filed Critical Behringwerke Ag
Publication of DK475779A publication Critical patent/DK475779A/en
Publication of DK154841B publication Critical patent/DK154841B/en
Application granted granted Critical
Publication of DK154841C publication Critical patent/DK154841C/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/02—Bacterial antigens
    • A61K39/095—Neisseria

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

1. Process for the isolation of membrane proteins from Neisseria meningitidis which comprises treating the organism with the aqueous solution of a detergent in a concentration of 0.1 to 2% w/v for 15 minutes to 24 hours, allowing the mixture to stand, optionally with agitation, separating the extract from the bacterial residue and optionally carrying out a further purification.
DK475779A 1978-11-11 1979-11-09 PROCEDURE FOR MANUFACTURING MEMBRANE PROTEINS FROM NEISSERIA MENINGITIDIS DK154841C (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE2848965 1978-11-11
DE19782848965 DE2848965A1 (en) 1978-11-11 1978-11-11 METHOD FOR PRODUCING MEMBRANE PROTEINS FROM NEISSERIA MENINGITIDIS AND VACCINE CONTAINING THEM

Publications (3)

Publication Number Publication Date
DK475779A true DK475779A (en) 1980-05-12
DK154841B DK154841B (en) 1988-12-27
DK154841C DK154841C (en) 1989-06-05

Family

ID=6054405

Family Applications (1)

Application Number Title Priority Date Filing Date
DK475779A DK154841C (en) 1978-11-11 1979-11-09 PROCEDURE FOR MANUFACTURING MEMBRANE PROTEINS FROM NEISSERIA MENINGITIDIS

Country Status (9)

Country Link
EP (1) EP0011243B1 (en)
JP (1) JPS5566519A (en)
AT (1) ATE857T1 (en)
AU (1) AU533386B2 (en)
CA (1) CA1142083A (en)
DE (2) DE2848965A1 (en)
DK (1) DK154841C (en)
ES (1) ES485715A1 (en)
IL (1) IL58673A (en)

Families Citing this family (49)

* Cited by examiner, † Cited by third party
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JPH074267B1 (en) * 1982-12-02 1995-01-25 Univ Rockefeller
US7118757B1 (en) 1988-12-19 2006-10-10 Wyeth Holdings Corporation Meningococcal class 1 outer-membrane protein vaccine
JP5074644B2 (en) 1998-05-29 2012-11-14 ノバルティス バクシンズ アンド ダイアグノスティックス，インコーポレーテッド Combination meningococcal B / C vaccine
CA2373236C (en) 1999-05-19 2014-08-26 Chiron S.P.A. Combination neisserial compositions
GB9918319D0 (en) 1999-08-03 1999-10-06 Smithkline Beecham Biolog Vaccine composition
GB9928196D0 (en) 1999-11-29 2000-01-26 Chiron Spa Combinations of B, C and other antigens
DK1897555T3 (en) 2000-01-17 2014-10-13 Novartis Vaccines & Diagnostic Supplemental OMV vaccine against meningococcus
GB0103171D0 (en) * 2001-02-08 2001-03-28 Smithkline Beecham Biolog Vaccine composition
JP4740738B2 (en) 2002-08-02 2011-08-03 グラクソスミスクライン バイオロジカルズ ソシエテ アノニム vaccine
GB0220194D0 (en) 2002-08-30 2002-10-09 Chiron Spa Improved vesicles
CU23313A1 (en) 2002-11-27 2008-09-25 Inst Finlay Ct De Investigacia MÃ0 / 00 METHOD OF OBTAINING COCLEAR STRUCTURES VACCINAL COMPOSITIONS AND ADJUSTS BASED ON COCLEAR STRUCTURES AND THEIR INTERMEDIARIES
GB0316560D0 (en) 2003-07-15 2003-08-20 Chiron Srl Vesicle filtration
US7628995B2 (en) * 2003-12-23 2009-12-08 Glaxosmithkline Biologicals S.A. Outer membrane vesicles and uses thereof
GB0419627D0 (en) 2004-09-03 2004-10-06 Chiron Srl Immunogenic bacterial vesicles with outer membrane proteins
GB0424092D0 (en) 2004-10-29 2004-12-01 Chiron Srl Immunogenic bacterial vesicles with outer membrane proteins
EP2032161B1 (en) 2006-06-12 2012-07-11 GlaxoSmithKline Biologicals S.A. L3v los vaccines
PL2200642T3 (en) 2007-10-19 2012-09-28 Novartis Ag Meningococcal vaccine formulations
AU2009215364B2 (en) 2008-02-21 2014-09-18 Glaxosmithkline Biologicals S.A. Meningococcal fHBP polypeptides
GB0822634D0 (en) 2008-12-11 2009-01-21 Novartis Ag Meningitis vaccines
BRPI0923006A2 (en) 2008-12-17 2016-03-08 Novartis Ag meningococcal vaccines including hemoglobin receptor
CA2765112A1 (en) 2009-06-10 2010-12-16 Novartis Ag Benzonaphthyridine-containing vaccines
WO2011024071A1 (en) 2009-08-27 2011-03-03 Novartis Ag Adjuvant comprising aluminium, oligonucleotide and polycation
US20110076300A1 (en) 2009-08-27 2011-03-31 Mariagrazia Pizza Hybrid Polypeptides Including Meningococcal fHBP Sequences
JO3257B1 (en) 2009-09-02 2018-09-16 Novartis Ag Compounds and compositions as tlr activity modulators
GB0917003D0 (en) 2009-09-28 2009-11-11 Novartis Vaccines Inst For Global Health Srl Purification of bacterial vesicles
CA2776004A1 (en) 2009-09-30 2011-04-07 Novartis Ag Expression of meningococcal fhbp polypeptides
US20130022633A1 (en) 2009-10-27 2013-01-24 University Of Florence MENINGOCOCCAL fHBP POLYPEPTIDES
WO2011057148A1 (en) 2009-11-05 2011-05-12 Irm Llc Compounds and compositions as tlr-7 activity modulators
CN102762206A (en) 2009-12-15 2012-10-31 诺华有限公司 Homogeneous suspension of immunopotentiating compounds and uses thereof
BR112012022688A2 (en) 2010-03-10 2018-05-22 Glaxosmithkline Biologicals Sa fusion protein, isolated outer membrane vesicle, polynucleotide, pharmaceutical composition, vaccine, method for treating or preventing neisseria infection or disease, use and method for making a fusion protein
BR112012022896A2 (en) 2010-03-18 2018-03-27 Novartis Ag adjuvant vaccines for serogroup b meningococci
CN102905703B (en) 2010-03-23 2016-09-28 诺华股份有限公司 As TLR2 agonist for treating compound (lipopeptid based on cysteine) and the compositions of infection, inflammation, respiratory disorder etc.
US9259462B2 (en) 2010-09-10 2016-02-16 Glaxosmithkline Biologicals Sa Developments in meningococcal outer membrane vesicles
GB201015132D0 (en) 2010-09-10 2010-10-27 Univ Bristol Vaccine composition
US20150147356A1 (en) 2011-05-12 2015-05-28 Alan Kimura Antipyretics to enhance tolerability of vesicle-based vaccines
US9657297B2 (en) 2012-02-02 2017-05-23 Glaxosmithkline Biologicals Sa Promoters for increased protein expression in meningococcus
EP2823312B1 (en) 2012-03-08 2019-08-07 GlaxoSmithKline Biologicals SA In vitro potency assay for protein-based meningococcal vaccines
RU2644340C2 (en) 2012-06-14 2018-02-08 Новартис Аг Vaccines for serogroup x meningococcus
US9526776B2 (en) 2012-09-06 2016-12-27 Glaxosmithkline Biologicals Sa Combination vaccines with serogroup B meningococcus and D/T/P
JP6283674B2 (en) 2012-09-18 2018-02-21 グラクソスミスクライン バイオロジカルズ ソシエテ アノニム Outer membrane vesicles
US10392424B2 (en) 2014-02-28 2019-08-27 Glaxosmithkline Biologicals Sa Modified meningococcal fHbp polypeptides
CA3035320A1 (en) 2016-09-02 2018-03-08 Glaxosmithkline Biologicals Sa Vaccines for neisseria gonorrhoeae
KR20200053531A (en) 2017-09-08 2020-05-18 에벨로 바이오사이언시즈, 인크. Bacterial extracellular vesicle
EP3607967A1 (en) 2018-08-09 2020-02-12 GlaxoSmithKline Biologicals S.A. Modified meningococcal fhbp polypeptides
EP3876982A1 (en) 2018-11-06 2021-09-15 GlaxoSmithKline Biologicals S.A. Immunogenic compositions
EP3799884A1 (en) 2019-10-01 2021-04-07 GlaxoSmithKline Biologicals S.A. Immunogenic compositions
GB202115072D0 (en) 2021-10-21 2021-12-08 Glaxosmithkline Biologicals Sa Assay
GB202115077D0 (en) 2021-10-21 2021-12-08 Glaxosmithkline Biologicals Sa Assay
GB202211033D0 (en) 2022-07-28 2022-09-14 Glaxosmithkline Biologicals Sa Purification process

Also Published As

Publication number Publication date
AU5268279A (en) 1980-05-15
ES485715A1 (en) 1980-05-16
ATE857T1 (en) 1982-04-15
AU533386B2 (en) 1983-11-24
IL58673A (en) 1983-02-23
DE2848965A1 (en) 1980-05-22
DK154841C (en) 1989-06-05
CA1142083A (en) 1983-03-01
DK154841B (en) 1988-12-27
EP0011243B1 (en) 1982-04-14
JPS6350332B2 (en) 1988-10-07
DE2962526D1 (en) 1982-05-27
JPS5566519A (en) 1980-05-20
IL58673A0 (en) 1980-02-29
EP0011243A1 (en) 1980-05-28

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