DE3485778T2 - Vielwertiges pneumokokken-vakzin und herstellung desselben. - Google Patents

Vielwertiges pneumokokken-vakzin und herstellung desselben.

Info

Publication number
DE3485778T2
DE3485778T2 DE8484105559T DE3485778T DE3485778T2 DE 3485778 T2 DE3485778 T2 DE 3485778T2 DE 8484105559 T DE8484105559 T DE 8484105559T DE 3485778 T DE3485778 T DE 3485778T DE 3485778 T2 DE3485778 T2 DE 3485778T2
Authority
DE
Germany
Prior art keywords
valuable
production
same
pneumococcal vaccine
pneumococcal
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE8484105559T
Other languages
English (en)
Other versions
DE3485778D1 (de
Inventor
Mary B Ritchey
Francis R Cano
Gerald J O'hara
James D English
Wenlii Lin
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Wyeth Holdings LLC
Original Assignee
American Cyanamid Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by American Cyanamid Co filed Critical American Cyanamid Co
Application granted granted Critical
Publication of DE3485778D1 publication Critical patent/DE3485778D1/de
Publication of DE3485778T2 publication Critical patent/DE3485778T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/02—Bacterial antigens
    • A61K39/09—Lactobacillales, e.g. aerococcus, enterococcus, lactobacillus, lactococcus, streptococcus
    • A61K39/092—Streptococcus
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S424/00—Drug, bio-affecting and body treating compositions
    • Y10S424/831—Drug, bio-affecting and body treating compositions involving capsular polysaccharide of bacterium, e.g. polyribosyl ribitol phosphate

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Medicinal Chemistry (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
DE8484105559T 1984-04-12 1984-05-16 Vielwertiges pneumokokken-vakzin und herstellung desselben. Expired - Lifetime DE3485778T2 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US06/599,318 US4686102A (en) 1984-04-12 1984-04-12 Multivalent pneumococcal vaccine and preparation thereof

Publications (2)

Publication Number Publication Date
DE3485778D1 DE3485778D1 (de) 1992-07-23
DE3485778T2 true DE3485778T2 (de) 1993-01-14

Family

ID=24399151

Family Applications (1)

Application Number Title Priority Date Filing Date
DE8484105559T Expired - Lifetime DE3485778T2 (de) 1984-04-12 1984-05-16 Vielwertiges pneumokokken-vakzin und herstellung desselben.

Country Status (9)

Country Link
US (1) US4686102A (de)
EP (1) EP0157899B1 (de)
JP (1) JPH0641422B2 (de)
AT (1) AT399655B (de)
AU (1) AU569946B2 (de)
CA (1) CA1216235A (de)
DE (1) DE3485778T2 (de)
ES (1) ES8602417A1 (de)
ZA (1) ZA852724B (de)

Families Citing this family (32)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4877613A (en) * 1987-08-05 1989-10-31 Biotech Connections, Inc. Process for preparing veterinary acellular vaccines against gram-negative nonenteric pathogenic bacilli
CA2059692C (en) * 1991-01-28 2004-11-16 Peter J. Kniskern Pneumoccoccal polysaccharide conjugate vaccine
CA2059693C (en) * 1991-01-28 2003-08-19 Peter J. Kniskern Polysaccharide antigens from streptococcus pneumoniae
US5314811A (en) * 1992-07-13 1994-05-24 Merck & Co., Inc. Process for converting lipid-containing bacterial capsular polysaccharide into lipid-free polysaccharide
US5371197A (en) * 1991-09-24 1994-12-06 Merck & Co., Inc. Protein-dimeric polysaccharide conjugate vaccine
US5314822A (en) * 1992-10-15 1994-05-24 Merck & Co., Inc. Method of clonal growth of Streptococcus pneumoniae
US5565204A (en) * 1994-08-24 1996-10-15 American Cyanamid Company Pneumococcal polysaccharide-recombinant pneumolysin conjugate vaccines for immunization against pneumococcal infections
US5714354A (en) * 1995-06-06 1998-02-03 American Home Products Corporation Alcohol-free pneumococcal polysaccharide purification process
JP3990455B2 (ja) * 1996-02-14 2007-10-10 メルク エンド カンパニー インコーポレーテッド 多糖沈殿法
US6410025B1 (en) 1996-02-14 2002-06-25 Merck & Co., Inc. Polysaccharide precipitation process
US6224880B1 (en) 1997-09-24 2001-05-01 Merck & Co., Inc. Immunization against Streptococcus pneumoniae using conjugated and unconjugated pneumoccocal polysaccharide vaccines
US6737524B2 (en) 2002-03-25 2004-05-18 Paul K. Smith Activated polyethylene glycol compounds
US7144989B2 (en) 2002-03-25 2006-12-05 Albert Einstein College Of Medicine Of Yeshiva University Pegylated non-hypertensive hemoglobins, methods of preparing same, and uses thereof
EP1625135B1 (de) * 2003-02-27 2009-04-08 Glaxo Group Limited Fondaparinux- natrium zusammenstellung von hoher reinheit
US7320874B2 (en) * 2003-07-08 2008-01-22 Aventis Pasteur Sa Assaying the teichoic acids of gram+ bacteria
EP1928419A1 (de) * 2005-09-30 2008-06-11 Lipoxen Technologies Limited Mehrwertige liposomale impstoff-zusammensetzungen aus polysaccharid-antigenen und einem protein-adjuvans
US8808707B1 (en) 2006-05-08 2014-08-19 Wyeth Llc Pneumococcal dosing regimen
SI2436700T1 (sl) 2007-03-23 2018-09-28 Wyeth Llc Skrajšan postopek čiščenja za proizvodnjo kapsularnih polisaharidov streptococcusa pneumoniae
US8128939B2 (en) 2007-04-13 2012-03-06 The Board Of Regents Of The University Of Oklahoma Mutants of cholesterol-dependent cytolysins and uses thereof
RU2511404C2 (ru) * 2008-12-18 2014-04-10 УАЙТ ЭлЭлСи Способ получения раствора, содержащего высокомолекулярные изолированные капсульные полисахариды streptococcus pneumoniae серотипа 19а (варианты)
RU2524436C2 (ru) * 2008-12-18 2014-07-27 УАЙТ ЭлЭлСи Способ получения жидкой фракции, содержащей изолированные высокомолекулярные капсульные полисахариды streptococcus pneumoniae, и жидкая фракция, полученная таким способом
AU2014214844B2 (en) 2013-02-07 2017-12-14 Children's Medical Center Corporation Protein antigens that provide protection against pneumococcal colonization and/or disease
MX371453B (es) * 2014-01-21 2020-01-29 Pfizer Polisacaridos capsulares de streptococcus pneumoniae y conjugados de los mismos.
AU2015208821B2 (en) * 2014-01-21 2017-11-02 Pfizer Inc. Immunogenic compositions comprising conjugated capsular saccharide antigens and uses thereof
US11160855B2 (en) 2014-01-21 2021-11-02 Pfizer Inc. Immunogenic compositions comprising conjugated capsular saccharide antigens and uses thereof
BR112017010696A2 (pt) 2014-11-21 2017-12-26 Univ Oklahoma mutantes de pneumolisina e métodos de utilização deste mutante
TWI756893B (zh) * 2015-07-21 2022-03-01 美商輝瑞股份有限公司 包含經共軛之莢膜糖抗原的致免疫性組成物、包含該致免疫性組成物之套組及彼等之用途
EP3436061A4 (de) 2016-03-31 2019-12-04 Liffey Biotech Limited Saccharid-polypeptidkonjugat-zusammensetzungen und verfahren zur verwendung davon
CA3052621A1 (en) 2017-02-03 2018-08-09 Schadeck, Eva Barbara Haemophilus influenzae saccharide-carrier conjugate compositions and uses thereof
EA201992636A1 (ru) 2017-05-05 2020-04-17 Серум Инститьют Оф Индия Прайват Лимитед Способ удаления примесей из препаратов на основе бактериальных капсулярных полисахаридов
KR20240018697A (ko) 2017-06-10 2024-02-13 인벤트프라이즈 인크. 면역원성과 항원항체 결합성이 개선된 2가 또는 다가 접합체 다당류를 가진 다가 접합체 백신
US10729763B2 (en) 2017-06-10 2020-08-04 Inventprise, Llc Mixtures of polysaccharide-protein pegylated compounds

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA1115210A (en) * 1977-11-28 1981-12-29 Dennis J. Carlo Pneumococcal vaccine
US4242501A (en) * 1979-08-08 1980-12-30 American Cyanamid Company Purification of pneumococcal capsular polysaccharides
BE889979A (fr) * 1981-08-14 1982-02-15 Smith Kline Rit Procede de preparation de polysaccharides bacteriens capsulaires antigeniques purifies, produits obtenus et leur utilisation

Also Published As

Publication number Publication date
EP0157899A3 (en) 1987-09-09
AU569946B2 (en) 1988-02-25
ES533263A0 (es) 1985-12-16
ATA109085A (de) 1994-11-15
AU4101685A (en) 1985-10-17
ZA852724B (en) 1985-11-27
JPS60218325A (ja) 1985-11-01
ES8602417A1 (es) 1985-12-16
AT399655B (de) 1995-06-26
US4686102A (en) 1987-08-11
DE3485778D1 (de) 1992-07-23
JPH0641422B2 (ja) 1994-06-01
EP0157899A2 (de) 1985-10-16
EP0157899B1 (de) 1992-06-17
CA1216235A (en) 1987-01-06

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8327 Change in the person/name/address of the patent owner

Owner name: WYETH HOLDINGS CORP., MADISON, N.J., US