AT399655B - Verfahren zur herstellung einer multivalenten pneumokokkenvakzine - Google Patents

Verfahren zur herstellung einer multivalenten pneumokokkenvakzine

Info

Publication number
AT399655B
AT399655B AT0109085A AT109085A AT399655B AT 399655 B AT399655 B AT 399655B AT 0109085 A AT0109085 A AT 0109085A AT 109085 A AT109085 A AT 109085A AT 399655 B AT399655 B AT 399655B
Authority
AT
Austria
Prior art keywords
pneumocock
multivalent
vaccine
producing
pneumocock vaccine
Prior art date
Application number
AT0109085A
Other languages
English (en)
Other versions
ATA109085A (de
Inventor
Mary B Ritchey
Francis R Cano
Gerald J O'hara
James D English
Wenlii Lin
Original Assignee
American Cyanamid Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by American Cyanamid Co filed Critical American Cyanamid Co
Publication of ATA109085A publication Critical patent/ATA109085A/de
Application granted granted Critical
Publication of AT399655B publication Critical patent/AT399655B/de

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/02—Bacterial antigens
    • A61K39/09—Lactobacillales, e.g. aerococcus, enterococcus, lactobacillus, lactococcus, streptococcus
    • A61K39/092—Streptococcus
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S424/00—Drug, bio-affecting and body treating compositions
    • Y10S424/831—Drug, bio-affecting and body treating compositions involving capsular polysaccharide of bacterium, e.g. polyribosyl ribitol phosphate

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Medicinal Chemistry (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
AT0109085A 1984-04-12 1985-04-11 Verfahren zur herstellung einer multivalenten pneumokokkenvakzine AT399655B (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US06/599,318 US4686102A (en) 1984-04-12 1984-04-12 Multivalent pneumococcal vaccine and preparation thereof

Publications (2)

Publication Number Publication Date
ATA109085A ATA109085A (de) 1994-11-15
AT399655B true AT399655B (de) 1995-06-26

Family

ID=24399151

Family Applications (1)

Application Number Title Priority Date Filing Date
AT0109085A AT399655B (de) 1984-04-12 1985-04-11 Verfahren zur herstellung einer multivalenten pneumokokkenvakzine

Country Status (9)

Country Link
US (1) US4686102A (de)
EP (1) EP0157899B1 (de)
JP (1) JPH0641422B2 (de)
AT (1) AT399655B (de)
AU (1) AU569946B2 (de)
CA (1) CA1216235A (de)
DE (1) DE3485778T2 (de)
ES (1) ES8602417A1 (de)
ZA (1) ZA852724B (de)

Families Citing this family (36)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4877613A (en) * 1987-08-05 1989-10-31 Biotech Connections, Inc. Process for preparing veterinary acellular vaccines against gram-negative nonenteric pathogenic bacilli
CA2059693C (en) * 1991-01-28 2003-08-19 Peter J. Kniskern Polysaccharide antigens from streptococcus pneumoniae
CA2059692C (en) * 1991-01-28 2004-11-16 Peter J. Kniskern Pneumoccoccal polysaccharide conjugate vaccine
US5314811A (en) * 1992-07-13 1994-05-24 Merck & Co., Inc. Process for converting lipid-containing bacterial capsular polysaccharide into lipid-free polysaccharide
US5371197A (en) * 1991-09-24 1994-12-06 Merck & Co., Inc. Protein-dimeric polysaccharide conjugate vaccine
US5314822A (en) * 1992-10-15 1994-05-24 Merck & Co., Inc. Method of clonal growth of Streptococcus pneumoniae
US5565204A (en) * 1994-08-24 1996-10-15 American Cyanamid Company Pneumococcal polysaccharide-recombinant pneumolysin conjugate vaccines for immunization against pneumococcal infections
US5714354A (en) * 1995-06-06 1998-02-03 American Home Products Corporation Alcohol-free pneumococcal polysaccharide purification process
US6410025B1 (en) 1996-02-14 2002-06-25 Merck & Co., Inc. Polysaccharide precipitation process
JP3990455B2 (ja) * 1996-02-14 2007-10-10 メルク エンド カンパニー インコーポレーテッド 多糖沈殿法
US6224880B1 (en) 1997-09-24 2001-05-01 Merck & Co., Inc. Immunization against Streptococcus pneumoniae using conjugated and unconjugated pneumoccocal polysaccharide vaccines
US7144989B2 (en) 2002-03-25 2006-12-05 Albert Einstein College Of Medicine Of Yeshiva University Pegylated non-hypertensive hemoglobins, methods of preparing same, and uses thereof
US6737524B2 (en) 2002-03-25 2004-05-18 Paul K. Smith Activated polyethylene glycol compounds
PT1625135E (pt) * 2003-02-27 2009-07-10 Glaxo Group Ltd Composição de fondaparinux sódico de pureza elevada
US7320874B2 (en) * 2003-07-08 2008-01-22 Aventis Pasteur Sa Assaying the teichoic acids of gram+ bacteria
ES2374648T3 (es) * 2005-09-30 2012-02-20 Lipoxen Technologies Limited Composiciones de vacunas liposómicas que comprenden un antígeno polisacárido y un adyuvante proteico.
US8808707B1 (en) 2006-05-08 2014-08-19 Wyeth Llc Pneumococcal dosing regimen
KR101500771B1 (ko) * 2007-03-23 2015-03-18 와이어쓰 엘엘씨 스트렙토코커스 뉴모니아 협막 다당류를 제조하기 위한 단축 정제 방법
AU2008287286B2 (en) 2007-04-13 2013-10-10 The Board Of Regents Of The University Of Oklahoma Mutants of cholesterol-dependent cytolysins and uses thereof
KR101593770B1 (ko) * 2008-12-18 2016-02-15 와이어쓰 엘엘씨 스트렙토코커스 뉴모니에 혈청형 19ａ 폴리사카라이드 분자량을 조절하는 방법
ES2749952T3 (es) 2008-12-18 2020-03-24 Wyeth Llc Procedimiento de control del peso molecular de polisacáridos de Streptococcus pneumoniae usando carbono
WO2014124228A1 (en) 2013-02-07 2014-08-14 Children's Medical Center Corporation Protein antigens that provide protection against pneumococcal colonization and/or disease
CN110859957B (zh) * 2014-01-21 2024-04-12 辉瑞公司 包含缀合荚膜糖抗原的免疫原性组合物及其用途
CN112336854B (zh) * 2014-01-21 2024-11-26 辉瑞大药厂 肺炎链球菌荚膜多糖及其缀合物
US11160855B2 (en) 2014-01-21 2021-11-02 Pfizer Inc. Immunogenic compositions comprising conjugated capsular saccharide antigens and uses thereof
ES2993430T3 (en) 2014-11-21 2024-12-30 Univ Oklahoma Pneumolysin mutants and methods of use thereof
KR20210027523A (ko) * 2015-07-21 2021-03-10 화이자 인코포레이티드 접합된 캡슐형 사카라이드 항원을 포함하는 면역원성 조성물, 그를 포함하는 키트 및 그의 용도
EP4488286A3 (de) 2016-03-31 2025-04-02 Pogona, Llc Saccharid-polypeptid-konjugat-zusammensetzungen und verfahren zu ihrer verwendung
US11246918B2 (en) 2017-02-03 2022-02-15 Eva Barbara Schadeck Haemophilus influenzae saccharide-carrier conjugate compositions and uses thereof
GEAP202215229A (en) 2017-05-05 2022-03-10 Serum Institute Of India Pvt Ltd Method for removal of impurities from bacterial capsular polysaccharide based preparations
US10729763B2 (en) 2017-06-10 2020-08-04 Inventprise, Llc Mixtures of polysaccharide-protein pegylated compounds
CN118356485A (zh) 2017-06-10 2024-07-19 创赏公司 提供改善的免疫原性和亲合力的具有二价或多价缀合物多糖的多价缀合物疫苗
US12257295B2 (en) 2017-10-04 2025-03-25 Pogona, LLC Saccharide-polypeptide conjugate compositions and methods of use thereof
CA3191005A1 (en) 2020-08-10 2022-02-17 Inventprise, Inc. Multivalent pneumococcal glycoconjugate vaccines containing emerging serotype 24f
CN116693706B (zh) * 2022-02-24 2024-10-11 成都生物制品研究所有限责任公司 一种肺炎链球菌荚膜多糖的纯化方法
CN116942804A (zh) 2022-04-19 2023-10-27 上海瑞宙生物科技有限公司 多价肺炎球菌多糖结合疫苗的成分及其应用

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0024493A2 (de) * 1979-08-08 1981-03-11 American Cyanamid Company Multivalenter Pneumokokkenimpfstoff

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA1115210A (en) * 1977-11-28 1981-12-29 Dennis J. Carlo Pneumococcal vaccine
BE889979A (fr) * 1981-08-14 1982-02-15 Smith Kline Rit Procede de preparation de polysaccharides bacteriens capsulaires antigeniques purifies, produits obtenus et leur utilisation

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0024493A2 (de) * 1979-08-08 1981-03-11 American Cyanamid Company Multivalenter Pneumokokkenimpfstoff

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
ANM. INT. MED. 96(5), 1982, PP. 580-6 *

Also Published As

Publication number Publication date
ES533263A0 (es) 1985-12-16
EP0157899A3 (en) 1987-09-09
AU569946B2 (en) 1988-02-25
CA1216235A (en) 1987-01-06
US4686102A (en) 1987-08-11
DE3485778T2 (de) 1993-01-14
JPS60218325A (ja) 1985-11-01
DE3485778D1 (de) 1992-07-23
AU4101685A (en) 1985-10-17
ES8602417A1 (es) 1985-12-16
ATA109085A (de) 1994-11-15
EP0157899B1 (de) 1992-06-17
EP0157899A2 (de) 1985-10-16
ZA852724B (en) 1985-11-27
JPH0641422B2 (ja) 1994-06-01

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Legal Events

Date Code Title Description
ELJ Ceased due to non-payment of the annual fee