ATE537813T1 - Liposomale impfstoff-zusammensetzung aus einem polysaccharid-antigen und einem protein-adjuvans - Google Patents
Liposomale impfstoff-zusammensetzung aus einem polysaccharid-antigen und einem protein-adjuvansInfo
- Publication number
- ATE537813T1 ATE537813T1 AT06806904T AT06806904T ATE537813T1 AT E537813 T1 ATE537813 T1 AT E537813T1 AT 06806904 T AT06806904 T AT 06806904T AT 06806904 T AT06806904 T AT 06806904T AT E537813 T1 ATE537813 T1 AT E537813T1
- Authority
- AT
- Austria
- Prior art keywords
- polysaccharide antigen
- vaccine composition
- liposomal vaccine
- protein adjuvant
- adjuvant
- Prior art date
Links
- 229960005486 vaccine Drugs 0.000 title abstract 3
- 239000000427 antigen Substances 0.000 title abstract 2
- 102000036639 antigens Human genes 0.000 title abstract 2
- 108091007433 antigens Proteins 0.000 title abstract 2
- 150000004676 glycans Chemical class 0.000 title abstract 2
- 229920001282 polysaccharide Polymers 0.000 title abstract 2
- 239000005017 polysaccharide Substances 0.000 title abstract 2
- 102000004169 proteins and genes Human genes 0.000 title abstract 2
- 108090000623 proteins and genes Proteins 0.000 title abstract 2
- 239000002671 adjuvant Substances 0.000 title 1
- 239000002502 liposome Substances 0.000 abstract 2
- 102000016607 Diphtheria Toxin Human genes 0.000 abstract 1
- 108010053187 Diphtheria Toxin Proteins 0.000 abstract 1
- 241000606768 Haemophilus influenzae Species 0.000 abstract 1
- 241000588650 Neisseria meningitidis Species 0.000 abstract 1
- 241000193998 Streptococcus pneumoniae Species 0.000 abstract 1
- 210000001744 T-lymphocyte Anatomy 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 230000001419 dependent effect Effects 0.000 abstract 1
- 229940047650 haemophilus influenzae Drugs 0.000 abstract 1
- 231100000252 nontoxic Toxicity 0.000 abstract 1
- 230000003000 nontoxic effect Effects 0.000 abstract 1
- 229940031000 streptococcus pneumoniae Drugs 0.000 abstract 1
- 229960000814 tetanus toxoid Drugs 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
- A61K9/127—Synthetic bilayered vehicles, e.g. liposomes or liposomes with cholesterol as the only non-phosphatidyl surfactant
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/02—Bacterial antigens
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/02—Bacterial antigens
- A61K39/09—Lactobacillales, e.g. aerococcus, enterococcus, lactobacillus, lactococcus, streptococcus
- A61K39/092—Streptococcus
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/39—Medicinal preparations containing antigens or antibodies characterised by the immunostimulating additives, e.g. chemical adjuvants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
- A61K9/127—Synthetic bilayered vehicles, e.g. liposomes or liposomes with cholesterol as the only non-phosphatidyl surfactant
- A61K9/1271—Non-conventional liposomes, e.g. PEGylated liposomes or liposomes coated or grafted with polymers
- A61K9/1272—Non-conventional liposomes, e.g. PEGylated liposomes or liposomes coated or grafted with polymers comprising non-phosphatidyl surfactants as bilayer-forming substances, e.g. cationic lipids or non-phosphatidyl liposomes coated or grafted with polymers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/04—Immunostimulants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
- A61K2039/55511—Organic adjuvants
- A61K2039/55544—Bacterial toxins
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
- A61K2039/55511—Organic adjuvants
- A61K2039/55555—Liposomes; Vesicles, e.g. nanoparticles; Spheres, e.g. nanospheres; Polymers
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Immunology (AREA)
- Epidemiology (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Mycology (AREA)
- Microbiology (AREA)
- Dispersion Chemistry (AREA)
- Biophysics (AREA)
- Molecular Biology (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
- Neurology (AREA)
- Biomedical Technology (AREA)
- Neurosurgery (AREA)
- Pulmonology (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Medicinal Preparation (AREA)
- Manufacturing Of Micro-Capsules (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP05256160 | 2005-09-30 | ||
| PCT/EP2006/066935 WO2007039583A1 (en) | 2005-09-30 | 2006-09-29 | Liposomal vaccine compositions comprising a polysaccharide antigen and a protein adjuvant |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE537813T1 true ATE537813T1 (de) | 2012-01-15 |
Family
ID=35841928
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT06806904T ATE537813T1 (de) | 2005-09-30 | 2006-09-29 | Liposomale impfstoff-zusammensetzung aus einem polysaccharid-antigen und einem protein-adjuvans |
Country Status (6)
| Country | Link |
|---|---|
| US (3) | US8753647B2 (de) |
| EP (2) | EP1928418B1 (de) |
| JP (2) | JP2009510032A (de) |
| AT (1) | ATE537813T1 (de) |
| ES (1) | ES2374648T3 (de) |
| WO (2) | WO2007039583A1 (de) |
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2010104883A1 (en) * | 2009-03-09 | 2010-09-16 | Molecular Express, Inc. | Methods and compositions for liposomal formulation of antigens and uses thereof |
| KR20110068831A (ko) | 2009-12-16 | 2011-06-22 | 재단법인 전라남도생물산업진흥재단 | 리포좀 조성물, 그 제조방법, 및 폐렴 백신으로서의 그 용도 |
| US9815886B2 (en) | 2014-10-28 | 2017-11-14 | Adma Biologics, Inc. | Compositions and methods for the treatment of immunodeficiency |
| US10259865B2 (en) | 2017-03-15 | 2019-04-16 | Adma Biologics, Inc. | Anti-pneumococcal hyperimmune globulin for the treatment and prevention of pneumococcal infection |
| EP3694490B1 (de) * | 2017-10-13 | 2024-03-20 | The Research Foundation for The State University of New York | Impfstoff-zubereitung gegen streptococcus pneumoniae, deren verwendung zur immunisierung eines individuums gegen s. pneumoniae und deren herstellungsmethode |
| US11491215B2 (en) * | 2018-05-24 | 2022-11-08 | Lawrence Livermore National Security, Llc | Antigenic combinations against Francisella bacteria and related nanolipoprotein particles, compositions, methods and systems |
| EP3890775A1 (de) * | 2018-12-06 | 2021-10-13 | GlaxoSmithKline Biologicals S.A. | Immunogene zusammensetzungen |
Family Cites Families (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4686102A (en) * | 1984-04-12 | 1987-08-11 | American Cyanamid Company | Multivalent pneumococcal vaccine and preparation thereof |
| AU648509B2 (en) | 1989-07-14 | 1994-04-28 | Wyeth Holdings Corporation | Stable vaccine compositions containing interleukins |
| IE912535A1 (en) * | 1990-07-27 | 1992-01-29 | Res Dev Foundation | Liposomes that Provide Thymic Dependent Help to Weak Vaccine¹Antigens |
| HUT67159A (en) * | 1991-05-13 | 1995-02-28 | Univ California | Liposomal polysaccharide vaccines |
| KR20010021953A (ko) * | 1997-07-17 | 2001-03-15 | 추후제출 | Ｂ군 수막염균 포린 및 에이치.인플루엔자 다당류를포함하는 면역원성 접합체 |
| AU1208499A (en) * | 1997-10-31 | 1999-05-24 | Cistron Biotechnology, Inc. | Encapsulated immunomodulators useful as vaccine adjuvants |
| GB9813100D0 (en) | 1998-06-18 | 1998-08-19 | Secr Defence | Method of forming liposomes |
| GB0225736D0 (en) * | 2002-11-05 | 2002-12-11 | Adjuvantix Ltd | T-Cell Independent Vaccine |
| EP1550458A1 (de) * | 2003-12-23 | 2005-07-06 | Vectron Therapeutics AG | Synergisitische liposomale Adjuvantien |
-
2006
- 2006-09-29 EP EP06806904A patent/EP1928418B1/de not_active Not-in-force
- 2006-09-29 WO PCT/EP2006/066935 patent/WO2007039583A1/en not_active Ceased
- 2006-09-29 WO PCT/EP2006/066938 patent/WO2007039584A1/en not_active Ceased
- 2006-09-29 ES ES06806904T patent/ES2374648T3/es active Active
- 2006-09-29 JP JP2008532805A patent/JP2009510032A/ja not_active Withdrawn
- 2006-09-29 JP JP2008532804A patent/JP5279497B2/ja not_active Expired - Fee Related
- 2006-09-29 AT AT06806904T patent/ATE537813T1/de active
- 2006-09-29 EP EP06806906A patent/EP1928419A1/de not_active Withdrawn
- 2006-09-29 US US12/088,672 patent/US8753647B2/en not_active Expired - Fee Related
- 2006-09-29 US US12/088,656 patent/US20090068254A1/en not_active Abandoned
-
2014
- 2014-05-07 US US14/272,313 patent/US9750692B2/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| JP2009510031A (ja) | 2009-03-12 |
| US20080317838A1 (en) | 2008-12-25 |
| US9750692B2 (en) | 2017-09-05 |
| EP1928418B1 (de) | 2011-12-21 |
| WO2007039583A1 (en) | 2007-04-12 |
| EP1928418A1 (de) | 2008-06-11 |
| US20140248337A1 (en) | 2014-09-04 |
| JP5279497B2 (ja) | 2013-09-04 |
| US8753647B2 (en) | 2014-06-17 |
| US20090068254A1 (en) | 2009-03-12 |
| ES2374648T3 (es) | 2012-02-20 |
| WO2007039584A1 (en) | 2007-04-12 |
| JP2009510032A (ja) | 2009-03-12 |
| EP1928419A1 (de) | 2008-06-11 |
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