DE2735904A1 - 1,5-disubstituierte-2-pyrrolidone und verfahren zu ihrer herstellung - Google Patents

1,5-disubstituierte-2-pyrrolidone und verfahren zu ihrer herstellung

Info

Publication number
DE2735904A1
DE2735904A1 DE19772735904 DE2735904A DE2735904A1 DE 2735904 A1 DE2735904 A1 DE 2735904A1 DE 19772735904 DE19772735904 DE 19772735904 DE 2735904 A DE2735904 A DE 2735904A DE 2735904 A1 DE2735904 A1 DE 2735904A1
Authority
DE
Germany
Prior art keywords
group
compound
phenyl
tetrazol
pyrrolidone
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
DE19772735904
Other languages
German (de)
English (en)
Inventor
Albin James Nelson
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
PFIZER
Pfizer Inc
Original Assignee
PFIZER
Pfizer Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by PFIZER, Pfizer Inc filed Critical PFIZER
Publication of DE2735904A1 publication Critical patent/DE2735904A1/de
Ceased legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/18—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
    • C07D207/22—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D207/24—Oxygen or sulfur atoms
    • C07D207/26—2-Pyrrolidones
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Pyrrole Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
DE19772735904 1976-08-06 1977-08-05 1,5-disubstituierte-2-pyrrolidone und verfahren zu ihrer herstellung Ceased DE2735904A1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US71236276A 1976-08-06 1976-08-06

Publications (1)

Publication Number Publication Date
DE2735904A1 true DE2735904A1 (de) 1978-02-09

Family

ID=24861795

Family Applications (1)

Application Number Title Priority Date Filing Date
DE19772735904 Ceased DE2735904A1 (de) 1976-08-06 1977-08-05 1,5-disubstituierte-2-pyrrolidone und verfahren zu ihrer herstellung

Country Status (31)

Country Link
JP (2) JPS5321159A (enExample)
AR (1) AR217080A1 (enExample)
AT (1) AT362887B (enExample)
AU (1) AU508007B2 (enExample)
BE (1) BE857506A (enExample)
BG (1) BG31073A3 (enExample)
CA (1) CA1077948A (enExample)
CH (1) CH624934A5 (enExample)
CS (1) CS221269B2 (enExample)
DD (2) DD143768A5 (enExample)
DE (1) DE2735904A1 (enExample)
DK (1) DK352077A (enExample)
ES (2) ES461388A1 (enExample)
FI (1) FI70009C (enExample)
FR (1) FR2369260A1 (enExample)
GB (2) GB1556570A (enExample)
GR (1) GR68688B (enExample)
HU (1) HU180273B (enExample)
IE (1) IE45505B1 (enExample)
IL (1) IL52615A (enExample)
LU (1) LU77936A1 (enExample)
NL (1) NL7708637A (enExample)
NO (1) NO772752L (enExample)
NZ (1) NZ184806A (enExample)
PH (1) PH17398A (enExample)
PL (2) PL112931B1 (enExample)
PT (1) PT66891B (enExample)
SE (1) SE423813B (enExample)
SU (3) SU703016A3 (enExample)
YU (1) YU192577A (enExample)
ZA (1) ZA774704B (enExample)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0048611A3 (en) * 1980-09-22 1982-06-16 E.I. Du Pont De Nemours And Company Optically active tert-alkyl 7-(2-oxo-5-carbonyloxypyrrolidinyl)heptanoates and process for their preparation
WO2003097596A1 (en) * 2002-05-14 2003-11-27 Allergan, Inc. 8-azaprostaglandin analogs as agents for lowering intraocular pressure

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5695569A (en) * 1979-12-27 1981-08-03 Canon Inc Forming method for bar lens sphere face
ATE327751T1 (de) 2000-01-31 2006-06-15 Pfizer Prod Inc Verwendung von aktivatoren des prostaglandinrezeptores 4 zur behandlung von akuter oder chronischer niereninsuffizienz
AU2001290250A1 (en) * 2000-09-21 2002-04-02 Ono Pharmaceutical Co. Ltd. Ep4 receptor agonists containing 8-azaprostaglandin derivatives as the active ingredient
EA200300379A1 (ru) * 2000-11-27 2003-08-28 Пфайзер Продактс Инк. Селективные агонисты рецептора ep4 в лечении остеопороза
JP4273407B2 (ja) * 2001-07-23 2009-06-03 小野薬品工業株式会社 Ｅｐ４アゴニストを有効成分とする骨量低下疾患の治療剤
ATE336247T1 (de) * 2002-03-18 2006-09-15 Pfizer Prod Inc Verwendung von selektiven ep4 rezeptor agonisten zur behandlung von krankheiten
WO2004065365A1 (ja) * 2003-01-21 2004-08-05 Ono Pharmaceutical Co., Ltd. ８−アザプロスタグランジン誘導体およびその医薬用途

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1386146A (en) * 1972-05-03 1975-03-05 Ici Ltd Cyclopentane derivatives
JPS511460A (en) * 1974-06-24 1976-01-08 Tanabe Seiyaku Co 22 piroridonjudotaino seiho
JPS514166A (ja) * 1974-06-28 1976-01-14 Tanabe Seiyaku Co 22piroridonjudotaino seiho
US3975399A (en) * 1974-08-06 1976-08-17 E. I. Du Pont De Nemours And Company 1,5-Disubstituted-2-pyrrolidinones, -3-pyrrolin-2-ones, and -4-pyrrolin-2-ones
DE2528664A1 (de) * 1975-06-27 1977-01-13 Hoechst Ag Pyrrolidone und verfahren zu ihrer herstellung

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
Tetrahedron-Letters, Nr. 51, 1975, S. 4599-4602 *

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0048611A3 (en) * 1980-09-22 1982-06-16 E.I. Du Pont De Nemours And Company Optically active tert-alkyl 7-(2-oxo-5-carbonyloxypyrrolidinyl)heptanoates and process for their preparation
WO2003097596A1 (en) * 2002-05-14 2003-11-27 Allergan, Inc. 8-azaprostaglandin analogs as agents for lowering intraocular pressure
US6906097B2 (en) 2002-05-14 2005-06-14 Allergan, Inc. 8-azaprostaglandin analogs as agents for lowering intraocular pressure

Also Published As

Publication number Publication date
CH624934A5 (enExample) 1981-08-31
CA1077948A (en) 1980-05-20
SU703016A3 (ru) 1979-12-05
JPS5555161A (en) 1980-04-22
ES471349A1 (es) 1979-09-16
PL112931B1 (en) 1980-11-29
FI70009C (fi) 1986-09-12
IE45505B1 (en) 1982-09-08
AU508007B2 (en) 1980-03-06
GB1556569A (en) 1979-11-28
PT66891A (en) 1977-09-01
ATA579477A (de) 1980-11-15
AU2751577A (en) 1979-02-08
HU180273B (en) 1983-02-28
NZ184806A (en) 1980-04-28
FI772376A7 (enExample) 1978-02-07
IE45505L (en) 1978-02-06
FR2369260B1 (enExample) 1982-02-12
FI70009B (fi) 1986-01-31
AT362887B (de) 1981-06-25
BE857506A (fr) 1978-02-06
CS221269B2 (en) 1983-04-29
PT66891B (en) 1979-01-26
DD136135A5 (de) 1979-06-20
SE7708642L (sv) 1978-02-07
PL200124A1 (pl) 1978-05-22
SU818480A3 (ru) 1981-03-30
SU850000A3 (ru) 1981-07-23
FR2369260A1 (fr) 1978-05-26
LU77936A1 (enExample) 1978-04-27
GB1556570A (en) 1979-11-28
ES461388A1 (es) 1978-12-01
AR217080A1 (es) 1980-02-29
DD143768A5 (de) 1980-09-10
JPS5531147B2 (enExample) 1980-08-15
ZA774704B (en) 1978-06-28
JPS5321159A (en) 1978-02-27
GR68688B (enExample) 1982-02-01
NL7708637A (nl) 1978-02-08
YU192577A (en) 1983-04-30
SE423813B (sv) 1982-06-07
IL52615A0 (en) 1977-10-31
DK352077A (da) 1978-02-07
IL52615A (en) 1981-09-13
PH17398A (en) 1984-08-08
BG31073A3 (bg) 1981-10-15
JPS585196B2 (ja) 1983-01-29
NO772752L (no) 1978-02-07

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Legal Events

Date Code Title Description
OAP Request for examination filed
OD Request for examination
OI Miscellaneous see part 1
OI Miscellaneous see part 1
8131 Rejection