FR2369260A1 - 2-pyrrolidones 1,5-disubstituees et leurs procedes de preparation - Google Patents

2-pyrrolidones 1,5-disubstituees et leurs procedes de preparation

Info

Publication number
FR2369260A1
FR2369260A1 FR7724290A FR7724290A FR2369260A1 FR 2369260 A1 FR2369260 A1 FR 2369260A1 FR 7724290 A FR7724290 A FR 7724290A FR 7724290 A FR7724290 A FR 7724290A FR 2369260 A1 FR2369260 A1 FR 2369260A1
Authority
FR
France
Prior art keywords
pyrrolidons
disubstituted
preparation methods
compounds
relates
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
FR7724290A
Other languages
English (en)
Other versions
FR2369260B1 (fr
Inventor
Albin James Nelson
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Pfizer Inc
Original Assignee
Pfizer Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer Inc filed Critical Pfizer Inc
Publication of FR2369260A1 publication Critical patent/FR2369260A1/fr
Application granted granted Critical
Publication of FR2369260B1 publication Critical patent/FR2369260B1/fr
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/18—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
    • C07D207/22—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D207/24—Oxygen or sulfur atoms
    • C07D207/26—2-Pyrrolidones
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Pyrrole Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)

Abstract

L'invention concerne de nouveaux composés du type prostaglandines de formule développée :
FR7724290A 1976-08-06 1977-08-05 2-pyrrolidones 1,5-disubstituees et leurs procedes de preparation Granted FR2369260A1 (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US71236276A 1976-08-06 1976-08-06

Publications (2)

Publication Number Publication Date
FR2369260A1 true FR2369260A1 (fr) 1978-05-26
FR2369260B1 FR2369260B1 (fr) 1982-02-12

Family

ID=24861795

Family Applications (1)

Application Number Title Priority Date Filing Date
FR7724290A Granted FR2369260A1 (fr) 1976-08-06 1977-08-05 2-pyrrolidones 1,5-disubstituees et leurs procedes de preparation

Country Status (31)

Country Link
JP (2) JPS5321159A (fr)
AR (1) AR217080A1 (fr)
AT (1) AT362887B (fr)
AU (1) AU508007B2 (fr)
BE (1) BE857506A (fr)
BG (1) BG31073A3 (fr)
CA (1) CA1077948A (fr)
CH (1) CH624934A5 (fr)
CS (1) CS221269B2 (fr)
DD (2) DD143768A5 (fr)
DE (1) DE2735904A1 (fr)
DK (1) DK352077A (fr)
ES (2) ES461388A1 (fr)
FI (1) FI70009C (fr)
FR (1) FR2369260A1 (fr)
GB (2) GB1556570A (fr)
GR (1) GR68688B (fr)
HU (1) HU180273B (fr)
IE (1) IE45505B1 (fr)
IL (1) IL52615A (fr)
LU (1) LU77936A1 (fr)
NL (1) NL7708637A (fr)
NO (1) NO772752L (fr)
NZ (1) NZ184806A (fr)
PH (1) PH17398A (fr)
PL (2) PL112931B1 (fr)
PT (1) PT66891B (fr)
SE (1) SE423813B (fr)
SU (3) SU703016A3 (fr)
YU (1) YU192577A (fr)
ZA (1) ZA774704B (fr)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5695569A (en) * 1979-12-27 1981-08-03 Canon Inc Forming method for bar lens sphere face
US4321201A (en) * 1980-09-22 1982-03-23 E. I. Du Pont De Nemours And Company Optically active tert-alkyl 7-(2-oxo-5-carbonyloxypyrrolidinyl) heptanoates
JPS59137224A (ja) * 1983-01-25 1984-08-07 Mitsubishi Electric Corp 電気鉄道用き電電圧補償装置
IL141120A0 (en) 2000-01-31 2002-02-10 Pfizer Prod Inc Use of prostaglandin (pge2) receptor 4 (epa) selective agonists for the treatment of acute and chronic renal failure
WO2002024647A1 (fr) * 2000-09-21 2002-03-28 Ono Pharmaceutical Co., Ltd. Agonistes du recepteur de l'ep4 comprenant comme principe actif des derives de la 8-azaprostaglandine
CN1476429A (zh) * 2000-11-27 2004-02-18 �Ʒ� 治疗骨质疏松的ep4受体选择性激动剂
WO2003009872A1 (fr) * 2001-07-23 2003-02-06 Ono Pharmaceutical Co., Ltd. Medicaments contenant un agoniste de ep4 en tant que principe actif destines aux maladies associees a une perte de la masse osseuse
DE60307607T2 (de) * 2002-03-18 2007-08-09 Pfizer Products Inc., Groton Verwendung von selektiven ep4 rezeptor agonisten zur behandlung von krankheiten
US6573294B1 (en) * 2002-05-14 2003-06-03 Allergan, Inc. 8-azaprostaglandin analogs as agents for lowering intraocular pressure
EP1586564B1 (fr) * 2003-01-21 2012-11-28 Ono Pharmaceutical Co., Ltd. Derives de 8-azaprostalangine et utilisations de ces derives en tant que medicaments

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3975399A (en) * 1974-08-06 1976-08-17 E. I. Du Pont De Nemours And Company 1,5-Disubstituted-2-pyrrolidinones, -3-pyrrolin-2-ones, and -4-pyrrolin-2-ones
FR2316943A1 (fr) * 1975-06-27 1977-02-04 Hoechst Ag Pyrrolidones et medicaments qui en contiennent

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1386146A (en) * 1972-05-03 1975-03-05 Ici Ltd Cyclopentane derivatives
JPS511460A (en) * 1974-06-24 1976-01-08 Tanabe Seiyaku Co 22 piroridonjudotaino seiho
JPS514166A (ja) * 1974-06-28 1976-01-14 Tanabe Seiyaku Co 22piroridonjudotaino seiho

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3975399A (en) * 1974-08-06 1976-08-17 E. I. Du Pont De Nemours And Company 1,5-Disubstituted-2-pyrrolidinones, -3-pyrrolin-2-ones, and -4-pyrrolin-2-ones
FR2316943A1 (fr) * 1975-06-27 1977-02-04 Hoechst Ag Pyrrolidones et medicaments qui en contiennent

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
EXBK/75 *

Also Published As

Publication number Publication date
ES471349A1 (es) 1979-09-16
PL112931B1 (en) 1980-11-29
YU192577A (en) 1983-04-30
ES461388A1 (es) 1978-12-01
SE423813B (sv) 1982-06-07
IL52615A (en) 1981-09-13
JPS585196B2 (ja) 1983-01-29
BE857506A (fr) 1978-02-06
GB1556569A (en) 1979-11-28
NZ184806A (en) 1980-04-28
GR68688B (fr) 1982-02-01
FI70009B (fi) 1986-01-31
AT362887B (de) 1981-06-25
BG31073A3 (en) 1981-10-15
PT66891B (en) 1979-01-26
JPS5555161A (en) 1980-04-22
AU508007B2 (en) 1980-03-06
JPS5321159A (en) 1978-02-27
IL52615A0 (en) 1977-10-31
PT66891A (en) 1977-09-01
CH624934A5 (fr) 1981-08-31
FI70009C (fi) 1986-09-12
HU180273B (en) 1983-02-28
FI772376A (fr) 1978-02-07
AR217080A1 (es) 1980-02-29
JPS5531147B2 (fr) 1980-08-15
CA1077948A (fr) 1980-05-20
GB1556570A (en) 1979-11-28
PH17398A (en) 1984-08-08
AU2751577A (en) 1979-02-08
ATA579477A (de) 1980-11-15
ZA774704B (en) 1978-06-28
LU77936A1 (fr) 1978-04-27
DD143768A5 (de) 1980-09-10
PL200124A1 (pl) 1978-05-22
SU850000A3 (ru) 1981-07-23
SU818480A3 (ru) 1981-03-30
NL7708637A (nl) 1978-02-08
DE2735904A1 (de) 1978-02-09
SE7708642L (sv) 1978-02-07
CS221269B2 (en) 1983-04-29
SU703016A3 (ru) 1979-12-05
DD136135A5 (de) 1979-06-20
DK352077A (da) 1978-02-07
NO772752L (no) 1978-02-07
FR2369260B1 (fr) 1982-02-12
IE45505L (en) 1978-02-06
IE45505B1 (en) 1982-09-08

Similar Documents

Publication Publication Date Title
FR2416891A1 (fr) 6-n-propyl-8-methoxymethyl ou methylmercaptomethylergolines et composes apparentes, et leur utilisation therapeutique
FR2435478A1 (fr) Derives spiro (indoline naphtoxazine) et leurs applications photochroniques
FR2415099A1 (fr) Nouveaux derives de 4-amino-5-alkylsulfonyl ortho-anisamides, leurs procedes de preparation et leur application comme psychotropes
FR2372822A1 (fr) Derives polyoxygenes du labdane, leurs procedes de preparation et leur application
FR2417510A1 (fr) 9-amino- et imino-dibenzopyrannes et leur utilisation therapeutique
FR2372806A1 (fr) Pyrrolidones, leur procede de preparation et leur application therapeutique
FR2392007A1 (fr) 3,3,3-triarylalkyl-4-phenylalkyl-4-hydroxy-piperidines, leurs derives, leur preparation et leur utilisation comme antidiarrheiques et analgesiques
FR2356651A1 (fr) Nouveaux derives d'acide penicillanique et leur utilisation therapeutique
FR2377402A1 (fr) 5h-imidazo(2,1-a)isoindole-2(3h),5-diones et leur utilisation comme herbicides
FR2446283A1 (fr) Phenoxyphenylpiperidines, leur preparation et leurs applications therapeutiques
FR2384783A1 (fr) Derives heteromonocycliques etheterobicycliques de l'acide 7 actylamido-3-cephem-4-carboxylique insature, procedes de preparation de ceux-ci, et utilisation en therapeutique
FR2369260A1 (fr) 2-pyrrolidones 1,5-disubstituees et leurs procedes de preparation
FR2375253A1 (fr) Preparations de g-lactones d'acides 7x-(alcoxycarbonyl)-6x -alkyl/halog 17-hydroxy-3-oxo-17a -pregn-4-ene-21-carboxyliques, des acides 21-carboxyliques correspondants, de leurs sels et esters, et leur utilisation therapeutique comme diuretiques
FR2384745A1 (fr) Derives de la somatostatine et leur preparation
FR2375239A1 (fr) Derives d'acide 7-amino-8-oxo-3-oxa-1-azabicyclo-(4.2.0)octane-2-carboxylique
FR2367777A1 (fr) Derives de steroides, leur preparation et leurs utilisations therapeutiques
FR2356626A1 (fr) Acides ureidoacetohydroxamiques substitues
FR2357558A1 (fr) 2,6-methano-2h-1-benzoxocines
FR2389631A1 (fr)
FR2429778A1 (fr) Nouvelles n,n'-bis((n-cyano-n'-alcynyl)methanimidamidyl)-cystamines
FR2359116A1 (fr) N-alkyldiphenylamines
FR2399465A1 (fr) Nouveaux complexes chromiferes 1 : 2, leur preparation et leur application comme colorants
FR2446282A1 (fr) Phenylthiophenylpiperidines, leur preparation et leurs applications therapeutiques
FR2445838A1 (fr) Nouveaux 1a,3b-dihydroxy-5-steroides
FR2371426A1 (fr) Nouvelles 15,16-dihydroxyprostaglandines, et leur utilisation therapeutique comme inhibiteurs de la secretion gastrique

Legal Events

Date Code Title Description
ST Notification of lapse