FR2417510A1 - 9-amino- et imino-dibenzopyrannes et leur utilisation therapeutique - Google Patents

9-amino- et imino-dibenzopyrannes et leur utilisation therapeutique

Info

Publication number
FR2417510A1
FR2417510A1 FR7903132A FR7903132A FR2417510A1 FR 2417510 A1 FR2417510 A1 FR 2417510A1 FR 7903132 A FR7903132 A FR 7903132A FR 7903132 A FR7903132 A FR 7903132A FR 2417510 A1 FR2417510 A1 FR 2417510A1
Authority
FR
France
Prior art keywords
dibenzopyrans
imino
amino
therapeutic use
therapeutic
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
FR7903132A
Other languages
English (en)
Other versions
FR2417510B1 (fr
Inventor
William Allen Day
Edward Ralph Lavagnino
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Eli Lilly and Co
Original Assignee
Eli Lilly and Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Eli Lilly and Co filed Critical Eli Lilly and Co
Publication of FR2417510A1 publication Critical patent/FR2417510A1/fr
Application granted granted Critical
Publication of FR2417510B1 publication Critical patent/FR2417510B1/fr
Granted legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D311/00Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
    • C07D311/02Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D311/78Ring systems having three or more relevant rings
    • C07D311/80Dibenzopyrans; Hydrogenated dibenzopyrans
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/22Anxiolytics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/24Antidepressants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/02Non-specific cardiovascular stimulants, e.g. drugs for syncope, antihypotensives

Abstract

L'invention concerne des composés de formule :
FR7903132A 1978-02-17 1979-02-07 9-amino- et imino-dibenzopyrannes et leur utilisation therapeutique Granted FR2417510A1 (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US05/878,844 US4152450A (en) 1978-02-17 1978-02-17 9-Amino-dibenzopyrans

Publications (2)

Publication Number Publication Date
FR2417510A1 true FR2417510A1 (fr) 1979-09-14
FR2417510B1 FR2417510B1 (fr) 1980-08-14

Family

ID=25372961

Family Applications (1)

Application Number Title Priority Date Filing Date
FR7903132A Granted FR2417510A1 (fr) 1978-02-17 1979-02-07 9-amino- et imino-dibenzopyrannes et leur utilisation therapeutique

Country Status (29)

Country Link
US (1) US4152450A (fr)
EP (1) EP0003883B1 (fr)
JP (1) JPS54122278A (fr)
AR (2) AR224359A1 (fr)
AT (1) AT366039B (fr)
AU (1) AU518718B2 (fr)
BE (1) BE873981A (fr)
CA (1) CA1111425A (fr)
CH (1) CH638800A5 (fr)
CS (1) CS207769B2 (fr)
DD (1) DD142190A5 (fr)
DE (1) DE2963797D1 (fr)
DK (1) DK68179A (fr)
ES (4) ES477832A1 (fr)
FI (1) FI790503A (fr)
FR (1) FR2417510A1 (fr)
GB (1) GB2014571B (fr)
GR (1) GR71465B (fr)
HU (1) HU180729B (fr)
IE (1) IE47999B1 (fr)
IL (1) IL56582A0 (fr)
LU (1) LU80922A1 (fr)
NZ (1) NZ189591A (fr)
PH (1) PH14622A (fr)
PL (5) PL121009B1 (fr)
PT (1) PT69202A (fr)
RO (5) RO82375A (fr)
SU (1) SU812177A3 (fr)
ZA (1) ZA79726B (fr)

Families Citing this family (28)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4309545A (en) * 1980-07-28 1982-01-05 Pfizer Inc. Oximino-1-hydroxyoctahydrobenzo[c]quinolines and derivatives thereof
US4351833A (en) * 1980-07-28 1982-09-28 Pfizer Inc. 9-Amino-1-hydroxyoctahydrobenzo[c]quinolines and derivatives thereof as analgesics and anti-emetics
US4486428A (en) * 1982-03-16 1984-12-04 Pfizer Inc. Bicyclic benzo fused compounds
US4642373A (en) * 1982-03-16 1987-02-10 Pfizer Inc. Substituted dodecahydrotripheylenes, and decahydropyrrolo[1,2-f]phenanthridines as CNS agents
US4870084A (en) * 1982-03-16 1989-09-26 Pfizer Inc. Bicyclic benzo fused pyran compounds used for nausea treatment and prevention
US4841078A (en) * 1982-03-16 1989-06-20 Pfizer Inc. Benzopyrans
US4863934A (en) * 1982-03-16 1989-09-05 Pfizer Inc. Bicyclic benzo fused pyran compounds used for producing analgesia
US4473704A (en) * 1982-03-16 1984-09-25 Pfizer Inc. Substituted dodecahydrotriphenylenes, decahydro-1H-cyclopenta[1]phenanthrenes, decahydro-1H-pyrido[1,2-f]phenanthridines and decahydropyrrolo[1,2-f]phenanthridines as CNS agents
US4442089A (en) * 1982-07-06 1984-04-10 E. R. Squibb & Sons, Inc. Method for treating glaucoma with topical or systemic ACE inhibitor compositions
US4680404A (en) * 1983-01-13 1987-07-14 Pfizer Inc. Benzopyrans
US5180736A (en) * 1989-03-23 1993-01-19 Warner-Lambert Company Polycyclic amines useful as cerebrovascular agents
ATE247097T1 (de) * 1998-05-04 2003-08-15 Univ Connecticut Analgetische und immunomodulierende cannabinoiden
US7897598B2 (en) * 1998-06-09 2011-03-01 Alexandros Makriyannis Inhibitors of the anandamide transporter
US7589220B2 (en) * 1998-06-09 2009-09-15 University Of Connecticut Inhibitors of the anandamide transporter
US7276613B1 (en) 1998-11-24 2007-10-02 University Of Connecticut Retro-anandamides, high affinity and stability cannabinoid receptor ligands
US7161016B1 (en) 1998-11-24 2007-01-09 University Of Connecticut Cannabimimetic lipid amides as useful medications
US7119108B1 (en) 1999-10-18 2006-10-10 University Of Connecticut Pyrazole derivatives as cannabinoid receptor antagonists
US6900236B1 (en) * 1999-10-18 2005-05-31 University Of Connecticut Cannabimimetic indole derivatives
US7741365B2 (en) * 1999-10-18 2010-06-22 University Of Connecticut Peripheral cannabinoid receptor (CB2) selective ligands
US7393842B2 (en) * 2001-08-31 2008-07-01 University Of Connecticut Pyrazole analogs acting on cannabinoid receptors
US6943266B1 (en) * 1999-10-18 2005-09-13 University Of Connecticut Bicyclic cannabinoid agonists for the cannabinoid receptor
US8084467B2 (en) * 1999-10-18 2011-12-27 University Of Connecticut Pyrazole derivatives as cannabinoid receptor antagonists
AU778159B2 (en) 1999-10-18 2004-11-18 University Of Connecticut, The Peripheral cannabinoid receptor (CB2) selective ligands
US7329651B2 (en) * 2001-01-26 2008-02-12 University Of Connecticut Cannabimimetic ligands
JP2005503998A (ja) 2001-01-29 2005-02-10 ユニバーシティ オブ コネチカット 受容体選択性のカンナビミメティックアミノアルキルインドール
JP4312594B2 (ja) 2001-07-13 2009-08-12 ユニバーシティ オブ コネチカット 新規な二環式及び三環式カンナビノイド
US7666867B2 (en) * 2001-10-26 2010-02-23 University Of Connecticut Heteroindanes: a new class of potent cannabimimetic ligands
CN1678303A (zh) 2002-08-23 2005-10-05 康涅狄格大学 具有治疗作用的酮类大麻类

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3676462A (en) * 1970-01-08 1972-07-11 Little Inc A 7,8,9,10-TETRAHYDRO (AND 7,8,9,10,11,12-HEXAHYDRO) 6H-DIBENZO {8 b,d{9 {0 PYRANS
US3649650A (en) * 1970-02-13 1972-03-14 Little Inc A Novel derivatives of tetrahydro-cannabinol
AU7612874A (en) * 1973-12-27 1976-06-10 Erba Carlo Spa Benzopyran derivatives

Also Published As

Publication number Publication date
SU812177A3 (ru) 1981-03-07
DK68179A (da) 1979-09-17
CS207769B2 (en) 1981-08-31
RO82369B (ro) 1983-07-30
RO82369A (fr) 1983-08-03
AR224359A1 (es) 1981-11-30
PL120658B1 (en) 1982-03-31
PL120645B1 (en) 1982-03-31
AT366039B (de) 1982-03-10
PL121009B1 (en) 1982-04-30
NZ189591A (en) 1980-10-08
RO82370B (ro) 1983-07-30
DE2963797D1 (en) 1982-11-11
ZA79726B (en) 1980-10-29
RO76886A (fr) 1982-02-01
ES485620A0 (es) 1980-07-16
CA1111425A (fr) 1981-10-27
GR71465B (fr) 1983-05-30
PL120661B1 (en) 1982-03-31
IE47999B1 (en) 1984-08-22
US4152450A (en) 1979-05-01
AU4398379A (en) 1979-08-23
FR2417510B1 (fr) 1980-08-14
PL118576B1 (en) 1981-10-31
PL213479A1 (fr) 1980-03-10
CH638800A5 (fr) 1983-10-14
AR225939A1 (es) 1982-05-14
BE873981A (fr) 1979-08-07
DD142190A5 (de) 1980-06-11
ES8502105A1 (es) 1980-07-16
RO82370A (fr) 1983-08-03
PH14622A (en) 1981-10-12
RO82376A (fr) 1983-08-03
AU518718B2 (en) 1981-10-15
EP0003883A1 (fr) 1979-09-05
PT69202A (en) 1979-03-01
ES8502106A1 (es) 1980-07-16
IL56582A0 (en) 1979-05-31
JPS54122278A (en) 1979-09-21
EP0003883B1 (fr) 1982-10-06
HU180729B (en) 1983-04-29
ES477832A1 (es) 1980-04-01
RO82376B (ro) 1983-07-30
GB2014571B (en) 1982-11-17
IE790304L (en) 1979-08-17
ES485621A1 (es) 1980-07-01
ATA123979A (de) 1981-07-15
GB2014571A (en) 1979-08-30
LU80922A1 (fr) 1979-06-18
RO82375A (fr) 1983-08-03
ES485619A0 (es) 1980-07-16
FI790503A (fi) 1979-08-18

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