DE2963797D1 - Amino-dibenzopyrans, their preparation, formulations containing them and their use as pharmaceuticals - Google Patents

Amino-dibenzopyrans, their preparation, formulations containing them and their use as pharmaceuticals

Info

Publication number
DE2963797D1
DE2963797D1 DE7979300211T DE2963797T DE2963797D1 DE 2963797 D1 DE2963797 D1 DE 2963797D1 DE 7979300211 T DE7979300211 T DE 7979300211T DE 2963797 T DE2963797 T DE 2963797T DE 2963797 D1 DE2963797 D1 DE 2963797D1
Authority
DE
Germany
Prior art keywords
dibenzopyrans
pharmaceuticals
amino
preparation
formulations containing
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
DE7979300211T
Other languages
English (en)
Inventor
William Allen Day
Edward Ralph Lavagnino
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Eli Lilly and Co
Original Assignee
Eli Lilly and Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Eli Lilly and Co filed Critical Eli Lilly and Co
Application granted granted Critical
Publication of DE2963797D1 publication Critical patent/DE2963797D1/de
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
    • C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D311/78—Ring systems having three or more relevant rings
    • C07D311/80—Dibenzopyrans; Hydrogenated dibenzopyrans
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/22—Anxiolytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/02—Non-specific cardiovascular stimulants, e.g. drugs for syncope, antihypotensives

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Pain & Pain Management (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Rheumatology (AREA)
  • Psychiatry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pyrane Compounds (AREA)
DE7979300211T 1978-02-17 1979-02-12 Amino-dibenzopyrans, their preparation, formulations containing them and their use as pharmaceuticals Expired DE2963797D1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US05/878,844 US4152450A (en) 1978-02-17 1978-02-17 9-Amino-dibenzopyrans

Publications (1)

Publication Number Publication Date
DE2963797D1 true DE2963797D1 (en) 1982-11-11

Family

ID=25372961

Family Applications (1)

Application Number Title Priority Date Filing Date
DE7979300211T Expired DE2963797D1 (en) 1978-02-17 1979-02-12 Amino-dibenzopyrans, their preparation, formulations containing them and their use as pharmaceuticals

Country Status (29)

Country Link
US (1) US4152450A (de)
EP (1) EP0003883B1 (de)
JP (1) JPS54122278A (de)
AR (2) AR224359A1 (de)
AT (1) AT366039B (de)
AU (1) AU518718B2 (de)
BE (1) BE873981A (de)
CA (1) CA1111425A (de)
CH (1) CH638800A5 (de)
CS (1) CS207769B2 (de)
DD (1) DD142190A5 (de)
DE (1) DE2963797D1 (de)
DK (1) DK68179A (de)
ES (4) ES477832A1 (de)
FI (1) FI790503A (de)
FR (1) FR2417510A1 (de)
GB (1) GB2014571B (de)
GR (1) GR71465B (de)
HU (1) HU180729B (de)
IE (1) IE47999B1 (de)
IL (1) IL56582A0 (de)
LU (1) LU80922A1 (de)
NZ (1) NZ189591A (de)
PH (1) PH14622A (de)
PL (5) PL121009B1 (de)
PT (1) PT69202A (de)
RO (5) RO76886A (de)
SU (1) SU812177A3 (de)
ZA (1) ZA79726B (de)

Families Citing this family (28)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4309545A (en) * 1980-07-28 1982-01-05 Pfizer Inc. Oximino-1-hydroxyoctahydrobenzo[c]quinolines and derivatives thereof
US4351833A (en) * 1980-07-28 1982-09-28 Pfizer Inc. 9-Amino-1-hydroxyoctahydrobenzo[c]quinolines and derivatives thereof as analgesics and anti-emetics
US4473704A (en) * 1982-03-16 1984-09-25 Pfizer Inc. Substituted dodecahydrotriphenylenes, decahydro-1H-cyclopenta[1]phenanthrenes, decahydro-1H-pyrido[1,2-f]phenanthridines and decahydropyrrolo[1,2-f]phenanthridines as CNS agents
US4841078A (en) * 1982-03-16 1989-06-20 Pfizer Inc. Benzopyrans
US4870084A (en) * 1982-03-16 1989-09-26 Pfizer Inc. Bicyclic benzo fused pyran compounds used for nausea treatment and prevention
US4642373A (en) * 1982-03-16 1987-02-10 Pfizer Inc. Substituted dodecahydrotripheylenes, and decahydropyrrolo[1,2-f]phenanthridines as CNS agents
US4486428A (en) * 1982-03-16 1984-12-04 Pfizer Inc. Bicyclic benzo fused compounds
US4863934A (en) * 1982-03-16 1989-09-05 Pfizer Inc. Bicyclic benzo fused pyran compounds used for producing analgesia
US4442089A (en) * 1982-07-06 1984-04-10 E. R. Squibb & Sons, Inc. Method for treating glaucoma with topical or systemic ACE inhibitor compositions
US4680404A (en) * 1983-01-13 1987-07-14 Pfizer Inc. Benzopyrans
US5180736A (en) * 1989-03-23 1993-01-19 Warner-Lambert Company Polycyclic amines useful as cerebrovascular agents
DE69910373T2 (de) * 1998-05-04 2004-04-01 The University Of Connecticut, Farmington Analgetische und immunomodulierende cannabinoiden
US7589220B2 (en) * 1998-06-09 2009-09-15 University Of Connecticut Inhibitors of the anandamide transporter
US7897598B2 (en) * 1998-06-09 2011-03-01 Alexandros Makriyannis Inhibitors of the anandamide transporter
US7276613B1 (en) 1998-11-24 2007-10-02 University Of Connecticut Retro-anandamides, high affinity and stability cannabinoid receptor ligands
US7161016B1 (en) 1998-11-24 2007-01-09 University Of Connecticut Cannabimimetic lipid amides as useful medications
US6900236B1 (en) * 1999-10-18 2005-05-31 University Of Connecticut Cannabimimetic indole derivatives
US6943266B1 (en) * 1999-10-18 2005-09-13 University Of Connecticut Bicyclic cannabinoid agonists for the cannabinoid receptor
US8084467B2 (en) * 1999-10-18 2011-12-27 University Of Connecticut Pyrazole derivatives as cannabinoid receptor antagonists
US7393842B2 (en) * 2001-08-31 2008-07-01 University Of Connecticut Pyrazole analogs acting on cannabinoid receptors
US7741365B2 (en) * 1999-10-18 2010-06-22 University Of Connecticut Peripheral cannabinoid receptor (CB2) selective ligands
WO2001028329A1 (en) 1999-10-18 2001-04-26 University Of Connecticut Peripheral cannabinoid receptor (cb2) selective ligands
US7119108B1 (en) 1999-10-18 2006-10-10 University Of Connecticut Pyrazole derivatives as cannabinoid receptor antagonists
WO2002058636A2 (en) * 2001-01-26 2002-08-01 University Of Connecticut Novel cannabimimetic ligands
WO2002060447A1 (en) 2001-01-29 2002-08-08 University Of Connecticut Receptor selective cannabimimetic aminoalkylindoles
EP1414775B1 (de) 2001-07-13 2012-12-19 The University of Connecticut Bicyclisches cannabinoid
CA2464333C (en) * 2001-10-26 2011-07-26 University Of Connecticut Heteroindanes: a new class of potent cannabimimetic ligands
US7183313B2 (en) 2002-08-23 2007-02-27 University Of Connecticut Keto cannabinoids with therapeutic indications

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3676462A (en) * 1970-01-08 1972-07-11 Little Inc A 7,8,9,10-TETRAHYDRO (AND 7,8,9,10,11,12-HEXAHYDRO) 6H-DIBENZO {8 b,d{9 {0 PYRANS
US3649650A (en) * 1970-02-13 1972-03-14 Little Inc A Novel derivatives of tetrahydro-cannabinol
AU7612874A (en) * 1973-12-27 1976-06-10 Erba Carlo Spa Benzopyran derivatives

Also Published As

Publication number Publication date
JPS54122278A (en) 1979-09-21
AR224359A1 (es) 1981-11-30
EP0003883A1 (de) 1979-09-05
LU80922A1 (fr) 1979-06-18
RO82370B (ro) 1983-07-30
CH638800A5 (fr) 1983-10-14
GB2014571A (en) 1979-08-30
PL213479A1 (de) 1980-03-10
IL56582A0 (en) 1979-05-31
IE790304L (en) 1979-08-17
PH14622A (en) 1981-10-12
GB2014571B (en) 1982-11-17
GR71465B (de) 1983-05-30
FI790503A (fi) 1979-08-18
IE47999B1 (en) 1984-08-22
FR2417510A1 (fr) 1979-09-14
SU812177A3 (ru) 1981-03-07
AR225939A1 (es) 1982-05-14
PL121009B1 (en) 1982-04-30
AU518718B2 (en) 1981-10-15
CA1111425A (en) 1981-10-27
CS207769B2 (en) 1981-08-31
DD142190A5 (de) 1980-06-11
EP0003883B1 (de) 1982-10-06
ES485621A1 (es) 1980-07-01
RO82376B (ro) 1983-07-30
RO82370A (ro) 1983-08-03
ES485619A0 (es) 1980-07-16
ATA123979A (de) 1981-07-15
RO76886A (ro) 1982-02-01
BE873981A (fr) 1979-08-07
DK68179A (da) 1979-09-17
PL120661B1 (en) 1982-03-31
RO82369A (ro) 1983-08-03
ES485620A0 (es) 1980-07-16
RO82369B (ro) 1983-07-30
ES8502105A1 (es) 1980-07-16
FR2417510B1 (de) 1980-08-14
RO82375A (ro) 1983-08-03
ES8502106A1 (es) 1980-07-16
PL120658B1 (en) 1982-03-31
PL120645B1 (en) 1982-03-31
NZ189591A (en) 1980-10-08
ES477832A1 (es) 1980-04-01
AU4398379A (en) 1979-08-23
ZA79726B (en) 1980-10-29
US4152450A (en) 1979-05-01
RO82376A (ro) 1983-08-03
HU180729B (en) 1983-04-29
AT366039B (de) 1982-03-10
PL118576B1 (en) 1981-10-31
PT69202A (en) 1979-03-01

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Legal Events

Date Code Title Description
8339 Ceased/non-payment of the annual fee