RO82369B - Procedeu pentru prepararea unor derivati de 9-amino-dibenzopiran - Google Patents

Procedeu pentru prepararea unor derivati de 9-amino-dibenzopiran

Info

Publication number
RO82369B
RO82369B RO104554A RO10455479A RO82369B RO 82369 B RO82369 B RO 82369B RO 104554 A RO104554 A RO 104554A RO 10455479 A RO10455479 A RO 10455479A RO 82369 B RO82369 B RO 82369B
Authority
RO
Romania
Prior art keywords
carbon atoms
amino
preparing
radical
derivatives
Prior art date
Application number
RO104554A
Other languages
English (en)
Other versions
RO82369A (ro
Inventor
William Allen Day
Edward Ralph Lavagnino
Original Assignee
Eli Lilly And Company
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Eli Lilly And Company filed Critical Eli Lilly And Company
Publication of RO82369B publication Critical patent/RO82369B/ro
Publication of RO82369A publication Critical patent/RO82369A/ro

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
    • C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D311/78—Ring systems having three or more relevant rings
    • C07D311/80—Dibenzopyrans; Hydrogenated dibenzopyrans
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/22—Anxiolytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/02—Non-specific cardiovascular stimulants, e.g. drugs for syncope, antihypotensives

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Pain & Pain Management (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Rheumatology (AREA)
  • Psychiatry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pyrane Compounds (AREA)

Abstract

Inventia se refera la un procedeu pentru prepararea unor derivati de 9-aminodibenzopiran cu formula din pag.1 a descrierii, în care R1 reprezinta un radical alcanoil cu 1...4 atomi de carbon, R2 reprezinta un radical alchil cu 5...10 atomi de carbon sau radical alchenil cu 5...10 atomi de carbon, R3 reprezinta un atom de hidrogen sau un radical metil si Z este ales dintre o grupare prezentata în pag.1.
RO79104554A 1978-02-17 1979-02-13 Procedeu pentru prepararea unor derivati de 9-aminodibenzoripiran RO82369A (ro)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US05/878,844 US4152450A (en) 1978-02-17 1978-02-17 9-Amino-dibenzopyrans

Publications (2)

Publication Number Publication Date
RO82369B true RO82369B (ro) 1983-07-30
RO82369A RO82369A (ro) 1983-08-03

Family

ID=25372961

Family Applications (5)

Application Number Title Priority Date Filing Date
RO79104554A RO82369A (ro) 1978-02-17 1979-02-13 Procedeu pentru prepararea unor derivati de 9-aminodibenzoripiran
RO79104556A RO82375A (ro) 1978-02-17 1979-02-13 Procedeu pentru prepararea de derivati ai 9-aminodibenzopiran
RO79104557A RO82376A (ro) 1978-02-17 1979-02-13 Procedeu pentru prepararea unor derivati de 9-hidroxiaminodimenzopirani
RO7996601A RO76886A (ro) 1978-02-17 1979-02-13 Procedeu pentru prepararea unor 9-iminodibenzopirani
RO79104555A RO82370A (ro) 1978-02-17 1979-02-13 Procedeu pentru prepararea unor derivati de 9-aminodibenzopiran

Family Applications After (4)

Application Number Title Priority Date Filing Date
RO79104556A RO82375A (ro) 1978-02-17 1979-02-13 Procedeu pentru prepararea de derivati ai 9-aminodibenzopiran
RO79104557A RO82376A (ro) 1978-02-17 1979-02-13 Procedeu pentru prepararea unor derivati de 9-hidroxiaminodimenzopirani
RO7996601A RO76886A (ro) 1978-02-17 1979-02-13 Procedeu pentru prepararea unor 9-iminodibenzopirani
RO79104555A RO82370A (ro) 1978-02-17 1979-02-13 Procedeu pentru prepararea unor derivati de 9-aminodibenzopiran

Country Status (29)

Country Link
US (1) US4152450A (ro)
EP (1) EP0003883B1 (ro)
JP (1) JPS54122278A (ro)
AR (2) AR224359A1 (ro)
AT (1) AT366039B (ro)
AU (1) AU518718B2 (ro)
BE (1) BE873981A (ro)
CA (1) CA1111425A (ro)
CH (1) CH638800A5 (ro)
CS (1) CS207769B2 (ro)
DD (1) DD142190A5 (ro)
DE (1) DE2963797D1 (ro)
DK (1) DK68179A (ro)
ES (4) ES477832A1 (ro)
FI (1) FI790503A7 (ro)
FR (1) FR2417510A1 (ro)
GB (1) GB2014571B (ro)
GR (1) GR71465B (ro)
HU (1) HU180729B (ro)
IE (1) IE47999B1 (ro)
IL (1) IL56582A0 (ro)
LU (1) LU80922A1 (ro)
NZ (1) NZ189591A (ro)
PH (1) PH14622A (ro)
PL (5) PL118576B1 (ro)
PT (1) PT69202A (ro)
RO (5) RO82369A (ro)
SU (1) SU812177A3 (ro)
ZA (1) ZA79726B (ro)

Families Citing this family (28)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4309545A (en) * 1980-07-28 1982-01-05 Pfizer Inc. Oximino-1-hydroxyoctahydrobenzo[c]quinolines and derivatives thereof
US4351833A (en) * 1980-07-28 1982-09-28 Pfizer Inc. 9-Amino-1-hydroxyoctahydrobenzo[c]quinolines and derivatives thereof as analgesics and anti-emetics
US4473704A (en) * 1982-03-16 1984-09-25 Pfizer Inc. Substituted dodecahydrotriphenylenes, decahydro-1H-cyclopenta[1]phenanthrenes, decahydro-1H-pyrido[1,2-f]phenanthridines and decahydropyrrolo[1,2-f]phenanthridines as CNS agents
US4486428A (en) * 1982-03-16 1984-12-04 Pfizer Inc. Bicyclic benzo fused compounds
US4863934A (en) * 1982-03-16 1989-09-05 Pfizer Inc. Bicyclic benzo fused pyran compounds used for producing analgesia
US4841078A (en) * 1982-03-16 1989-06-20 Pfizer Inc. Benzopyrans
US4870084A (en) * 1982-03-16 1989-09-26 Pfizer Inc. Bicyclic benzo fused pyran compounds used for nausea treatment and prevention
US4642373A (en) * 1982-03-16 1987-02-10 Pfizer Inc. Substituted dodecahydrotripheylenes, and decahydropyrrolo[1,2-f]phenanthridines as CNS agents
US4442089A (en) * 1982-07-06 1984-04-10 E. R. Squibb & Sons, Inc. Method for treating glaucoma with topical or systemic ACE inhibitor compositions
US4680404A (en) * 1983-01-13 1987-07-14 Pfizer Inc. Benzopyrans
US5180736A (en) * 1989-03-23 1993-01-19 Warner-Lambert Company Polycyclic amines useful as cerebrovascular agents
WO1999057106A1 (en) * 1998-05-04 1999-11-11 The University Of Connecticut Novel analgesic and immunomodulatory cannabinoids
US7589220B2 (en) * 1998-06-09 2009-09-15 University Of Connecticut Inhibitors of the anandamide transporter
US7897598B2 (en) * 1998-06-09 2011-03-01 Alexandros Makriyannis Inhibitors of the anandamide transporter
US7161016B1 (en) 1998-11-24 2007-01-09 University Of Connecticut Cannabimimetic lipid amides as useful medications
US7276613B1 (en) 1998-11-24 2007-10-02 University Of Connecticut Retro-anandamides, high affinity and stability cannabinoid receptor ligands
US8084467B2 (en) * 1999-10-18 2011-12-27 University Of Connecticut Pyrazole derivatives as cannabinoid receptor antagonists
US7741365B2 (en) * 1999-10-18 2010-06-22 University Of Connecticut Peripheral cannabinoid receptor (CB2) selective ligands
US6943266B1 (en) 1999-10-18 2005-09-13 University Of Connecticut Bicyclic cannabinoid agonists for the cannabinoid receptor
US7393842B2 (en) * 2001-08-31 2008-07-01 University Of Connecticut Pyrazole analogs acting on cannabinoid receptors
US6900236B1 (en) 1999-10-18 2005-05-31 University Of Connecticut Cannabimimetic indole derivatives
WO2001028329A1 (en) 1999-10-18 2001-04-26 University Of Connecticut Peripheral cannabinoid receptor (cb2) selective ligands
US7119108B1 (en) * 1999-10-18 2006-10-10 University Of Connecticut Pyrazole derivatives as cannabinoid receptor antagonists
US7329651B2 (en) * 2001-01-26 2008-02-12 University Of Connecticut Cannabimimetic ligands
CA2436133A1 (en) 2001-01-29 2002-08-08 University Of Connecticut Receptor selective cannabimimetic aminoalkylindoles
US7057076B2 (en) 2001-07-13 2006-06-06 University Of Connecticut Bicyclic and tricyclic cannabinoids
WO2003035005A2 (en) * 2001-10-26 2003-05-01 University Of Connecticut Heteroindanes: a new class of potent cannabimimetic ligands
WO2004017922A2 (en) 2002-08-23 2004-03-04 University Of Connecticut Keto cannabinoids with therapeutic indications

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3676462A (en) * 1970-01-08 1972-07-11 Little Inc A 7,8,9,10-TETRAHYDRO (AND 7,8,9,10,11,12-HEXAHYDRO) 6H-DIBENZO {8 b,d{9 {0 PYRANS
US3649650A (en) * 1970-02-13 1972-03-14 Little Inc A Novel derivatives of tetrahydro-cannabinol
AU7612874A (en) * 1973-12-27 1976-06-10 Erba Carlo Spa Benzopyran derivatives

Also Published As

Publication number Publication date
PL120645B1 (en) 1982-03-31
PL120658B1 (en) 1982-03-31
FR2417510A1 (fr) 1979-09-14
DD142190A5 (de) 1980-06-11
AT366039B (de) 1982-03-10
PL120661B1 (en) 1982-03-31
AU518718B2 (en) 1981-10-15
ES485621A1 (es) 1980-07-01
RO82369A (ro) 1983-08-03
IL56582A0 (en) 1979-05-31
PL213479A1 (ro) 1980-03-10
GR71465B (ro) 1983-05-30
RO82376B (ro) 1983-07-30
AR225939A1 (es) 1982-05-14
GB2014571B (en) 1982-11-17
RO82376A (ro) 1983-08-03
LU80922A1 (fr) 1979-06-18
DE2963797D1 (en) 1982-11-11
IE47999B1 (en) 1984-08-22
EP0003883B1 (en) 1982-10-06
US4152450A (en) 1979-05-01
DK68179A (da) 1979-09-17
AR224359A1 (es) 1981-11-30
PH14622A (en) 1981-10-12
CS207769B2 (en) 1981-08-31
JPS54122278A (en) 1979-09-21
SU812177A3 (ru) 1981-03-07
BE873981A (fr) 1979-08-07
ES485620A0 (es) 1980-07-16
NZ189591A (en) 1980-10-08
ES8502106A1 (es) 1980-07-16
ZA79726B (en) 1980-10-29
IE790304L (en) 1979-08-17
HU180729B (en) 1983-04-29
CH638800A5 (fr) 1983-10-14
ES477832A1 (es) 1980-04-01
ES8502105A1 (es) 1980-07-16
CA1111425A (en) 1981-10-27
RO82370B (ro) 1983-07-30
ES485619A0 (es) 1980-07-16
PL121009B1 (en) 1982-04-30
GB2014571A (en) 1979-08-30
PL118576B1 (en) 1981-10-31
FI790503A7 (fi) 1979-08-18
ATA123979A (de) 1981-07-15
RO82370A (ro) 1983-08-03
PT69202A (en) 1979-03-01
FR2417510B1 (ro) 1980-08-14
RO82375A (ro) 1983-08-03
EP0003883A1 (en) 1979-09-05
RO76886A (ro) 1982-02-01
AU4398379A (en) 1979-08-23

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