RO82369B - Procedeu pentru prepararea unor derivati de 9-amino-dibenzopiran - Google Patents
Procedeu pentru prepararea unor derivati de 9-amino-dibenzopiranInfo
- Publication number
- RO82369B RO82369B RO104554A RO10455479A RO82369B RO 82369 B RO82369 B RO 82369B RO 104554 A RO104554 A RO 104554A RO 10455479 A RO10455479 A RO 10455479A RO 82369 B RO82369 B RO 82369B
- Authority
- RO
- Romania
- Prior art keywords
- carbon atoms
- amino
- preparing
- radical
- derivatives
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
- C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D311/78—Ring systems having three or more relevant rings
- C07D311/80—Dibenzopyrans; Hydrogenated dibenzopyrans
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/22—Anxiolytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/02—Non-specific cardiovascular stimulants, e.g. drugs for syncope, antihypotensives
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Heart & Thoracic Surgery (AREA)
- Cardiology (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Pain & Pain Management (AREA)
- Rheumatology (AREA)
- Psychiatry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Plural Heterocyclic Compounds (AREA)
- Pyrane Compounds (AREA)
Abstract
Inventia se refera la un procedeu pentru prepararea unor derivati de 9-aminodibenzopiran cu formula din pag.1 a descrierii, în care R1 reprezinta un radical alcanoil cu 1...4 atomi de carbon, R2 reprezinta un radical alchil cu 5...10 atomi de carbon sau radical alchenil cu 5...10 atomi de carbon, R3 reprezinta un atom de hidrogen sau un radical metil si Z este ales dintre o grupare prezentata în pag.1.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US05/878,844 US4152450A (en) | 1978-02-17 | 1978-02-17 | 9-Amino-dibenzopyrans |
Publications (2)
Publication Number | Publication Date |
---|---|
RO82369B true RO82369B (ro) | 1983-07-30 |
RO82369A RO82369A (ro) | 1983-08-03 |
Family
ID=25372961
Family Applications (5)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
RO79104557A RO82376A (ro) | 1978-02-17 | 1979-02-13 | Procedeu pentru prepararea unor derivati de 9-hidroxiaminodimenzopirani |
RO7996601A RO76886A (ro) | 1978-02-17 | 1979-02-13 | Procedeu pentru prepararea unor 9-iminodibenzopirani |
RO79104556A RO82375A (ro) | 1978-02-17 | 1979-02-13 | Procedeu pentru prepararea de derivati ai 9-aminodibenzopiran |
RO79104555A RO82370A (ro) | 1978-02-17 | 1979-02-13 | Procedeu pentru prepararea unor derivati de 9-aminodibenzopiran |
RO79104554A RO82369A (ro) | 1978-02-17 | 1979-02-13 | Procedeu pentru prepararea unor derivati de 9-aminodibenzoripiran |
Family Applications Before (4)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
RO79104557A RO82376A (ro) | 1978-02-17 | 1979-02-13 | Procedeu pentru prepararea unor derivati de 9-hidroxiaminodimenzopirani |
RO7996601A RO76886A (ro) | 1978-02-17 | 1979-02-13 | Procedeu pentru prepararea unor 9-iminodibenzopirani |
RO79104556A RO82375A (ro) | 1978-02-17 | 1979-02-13 | Procedeu pentru prepararea de derivati ai 9-aminodibenzopiran |
RO79104555A RO82370A (ro) | 1978-02-17 | 1979-02-13 | Procedeu pentru prepararea unor derivati de 9-aminodibenzopiran |
Country Status (29)
Country | Link |
---|---|
US (1) | US4152450A (ro) |
EP (1) | EP0003883B1 (ro) |
JP (1) | JPS54122278A (ro) |
AR (2) | AR224359A1 (ro) |
AT (1) | AT366039B (ro) |
AU (1) | AU518718B2 (ro) |
BE (1) | BE873981A (ro) |
CA (1) | CA1111425A (ro) |
CH (1) | CH638800A5 (ro) |
CS (1) | CS207769B2 (ro) |
DD (1) | DD142190A5 (ro) |
DE (1) | DE2963797D1 (ro) |
DK (1) | DK68179A (ro) |
ES (4) | ES477832A1 (ro) |
FI (1) | FI790503A (ro) |
FR (1) | FR2417510A1 (ro) |
GB (1) | GB2014571B (ro) |
GR (1) | GR71465B (ro) |
HU (1) | HU180729B (ro) |
IE (1) | IE47999B1 (ro) |
IL (1) | IL56582A0 (ro) |
LU (1) | LU80922A1 (ro) |
NZ (1) | NZ189591A (ro) |
PH (1) | PH14622A (ro) |
PL (5) | PL118576B1 (ro) |
PT (1) | PT69202A (ro) |
RO (5) | RO82376A (ro) |
SU (1) | SU812177A3 (ro) |
ZA (1) | ZA79726B (ro) |
Families Citing this family (28)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4351833A (en) * | 1980-07-28 | 1982-09-28 | Pfizer Inc. | 9-Amino-1-hydroxyoctahydrobenzo[c]quinolines and derivatives thereof as analgesics and anti-emetics |
US4309545A (en) * | 1980-07-28 | 1982-01-05 | Pfizer Inc. | Oximino-1-hydroxyoctahydrobenzo[c]quinolines and derivatives thereof |
US4841078A (en) * | 1982-03-16 | 1989-06-20 | Pfizer Inc. | Benzopyrans |
US4473704A (en) * | 1982-03-16 | 1984-09-25 | Pfizer Inc. | Substituted dodecahydrotriphenylenes, decahydro-1H-cyclopenta[1]phenanthrenes, decahydro-1H-pyrido[1,2-f]phenanthridines and decahydropyrrolo[1,2-f]phenanthridines as CNS agents |
US4870084A (en) * | 1982-03-16 | 1989-09-26 | Pfizer Inc. | Bicyclic benzo fused pyran compounds used for nausea treatment and prevention |
US4642373A (en) * | 1982-03-16 | 1987-02-10 | Pfizer Inc. | Substituted dodecahydrotripheylenes, and decahydropyrrolo[1,2-f]phenanthridines as CNS agents |
US4863934A (en) * | 1982-03-16 | 1989-09-05 | Pfizer Inc. | Bicyclic benzo fused pyran compounds used for producing analgesia |
US4486428A (en) * | 1982-03-16 | 1984-12-04 | Pfizer Inc. | Bicyclic benzo fused compounds |
US4442089A (en) * | 1982-07-06 | 1984-04-10 | E. R. Squibb & Sons, Inc. | Method for treating glaucoma with topical or systemic ACE inhibitor compositions |
US4680404A (en) * | 1983-01-13 | 1987-07-14 | Pfizer Inc. | Benzopyrans |
US5180736A (en) * | 1989-03-23 | 1993-01-19 | Warner-Lambert Company | Polycyclic amines useful as cerebrovascular agents |
DE69910373T2 (de) * | 1998-05-04 | 2004-04-01 | The University Of Connecticut, Farmington | Analgetische und immunomodulierende cannabinoiden |
US7897598B2 (en) * | 1998-06-09 | 2011-03-01 | Alexandros Makriyannis | Inhibitors of the anandamide transporter |
US7589220B2 (en) * | 1998-06-09 | 2009-09-15 | University Of Connecticut | Inhibitors of the anandamide transporter |
US7276613B1 (en) | 1998-11-24 | 2007-10-02 | University Of Connecticut | Retro-anandamides, high affinity and stability cannabinoid receptor ligands |
US7161016B1 (en) | 1998-11-24 | 2007-01-09 | University Of Connecticut | Cannabimimetic lipid amides as useful medications |
US7119108B1 (en) * | 1999-10-18 | 2006-10-10 | University Of Connecticut | Pyrazole derivatives as cannabinoid receptor antagonists |
MXPA02005103A (es) | 1999-10-18 | 2003-09-25 | Alexipharma Inc | Ligandos selectivos del receptor de canabinoide (cb2) perifericos. |
US7741365B2 (en) * | 1999-10-18 | 2010-06-22 | University Of Connecticut | Peripheral cannabinoid receptor (CB2) selective ligands |
US7393842B2 (en) * | 2001-08-31 | 2008-07-01 | University Of Connecticut | Pyrazole analogs acting on cannabinoid receptors |
US6943266B1 (en) | 1999-10-18 | 2005-09-13 | University Of Connecticut | Bicyclic cannabinoid agonists for the cannabinoid receptor |
US8084467B2 (en) * | 1999-10-18 | 2011-12-27 | University Of Connecticut | Pyrazole derivatives as cannabinoid receptor antagonists |
US6900236B1 (en) | 1999-10-18 | 2005-05-31 | University Of Connecticut | Cannabimimetic indole derivatives |
JP2004532185A (ja) * | 2001-01-26 | 2004-10-21 | ユニバーシティ オブ コネチカット | 新規なカンナビミメティックリガンド |
DE60237431D1 (de) | 2001-01-29 | 2010-10-07 | Univ Connecticut | Rezeptor-selektive cannabimimetische aminoalkylindole |
CA2452881C (en) * | 2001-07-13 | 2012-03-06 | University Of Connecticut | Novel bicyclic and tricyclic cannabinoids |
CA2464333C (en) * | 2001-10-26 | 2011-07-26 | University Of Connecticut | Heteroindanes: a new class of potent cannabimimetic ligands |
US7183313B2 (en) | 2002-08-23 | 2007-02-27 | University Of Connecticut | Keto cannabinoids with therapeutic indications |
Family Cites Families (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3676462A (en) * | 1970-01-08 | 1972-07-11 | Little Inc A | 7,8,9,10-TETRAHYDRO (AND 7,8,9,10,11,12-HEXAHYDRO) 6H-DIBENZO {8 b,d{9 {0 PYRANS |
US3649650A (en) * | 1970-02-13 | 1972-03-14 | Little Inc A | Novel derivatives of tetrahydro-cannabinol |
AU7612874A (en) * | 1973-12-27 | 1976-06-10 | Erba Carlo Spa | Benzopyran derivatives |
-
1978
- 1978-02-17 US US05/878,844 patent/US4152450A/en not_active Expired - Lifetime
-
1979
- 1979-02-04 IL IL56582A patent/IL56582A0/xx unknown
- 1979-02-05 PH PH22162A patent/PH14622A/en unknown
- 1979-02-06 CA CA320,950A patent/CA1111425A/en not_active Expired
- 1979-02-06 AU AU43983/79A patent/AU518718B2/en not_active Ceased
- 1979-02-07 FR FR7903132A patent/FR2417510A1/fr active Granted
- 1979-02-07 BE BE1/9263A patent/BE873981A/xx not_active IP Right Cessation
- 1979-02-07 NZ NZ189591A patent/NZ189591A/xx unknown
- 1979-02-08 PT PT7969202A patent/PT69202A/pt unknown
- 1979-02-12 GB GB7904934A patent/GB2014571B/en not_active Expired
- 1979-02-12 EP EP79300211A patent/EP0003883B1/en not_active Expired
- 1979-02-12 DE DE7979300211T patent/DE2963797D1/de not_active Expired
- 1979-02-13 RO RO79104557A patent/RO82376A/ro unknown
- 1979-02-13 RO RO7996601A patent/RO76886A/ro unknown
- 1979-02-13 AR AR275486A patent/AR224359A1/es active
- 1979-02-13 RO RO79104556A patent/RO82375A/ro unknown
- 1979-02-13 RO RO79104555A patent/RO82370A/ro unknown
- 1979-02-13 RO RO79104554A patent/RO82369A/ro unknown
- 1979-02-14 GR GR58370A patent/GR71465B/el unknown
- 1979-02-15 JP JP1716279A patent/JPS54122278A/ja active Pending
- 1979-02-15 HU HU79EI840A patent/HU180729B/hu unknown
- 1979-02-15 FI FI790503A patent/FI790503A/fi unknown
- 1979-02-15 LU LU80922A patent/LU80922A1/xx unknown
- 1979-02-16 PL PL1979213479A patent/PL118576B1/pl unknown
- 1979-02-16 DD DD79211056A patent/DD142190A5/de unknown
- 1979-02-16 DK DK68179A patent/DK68179A/da not_active Application Discontinuation
- 1979-02-16 AT AT0123979A patent/AT366039B/de not_active IP Right Cessation
- 1979-02-16 IE IE304/79A patent/IE47999B1/en unknown
- 1979-02-16 PL PL1979227605A patent/PL120661B1/pl unknown
- 1979-02-16 PL PL1979227604A patent/PL121009B1/pl unknown
- 1979-02-16 PL PL1979227606A patent/PL120645B1/pl unknown
- 1979-02-16 ES ES477832A patent/ES477832A1/es not_active Expired
- 1979-02-16 CH CH158279A patent/CH638800A5/fr not_active IP Right Cessation
- 1979-02-16 SU SU792728600A patent/SU812177A3/ru active
- 1979-02-16 PL PL1979227607A patent/PL120658B1/pl unknown
- 1979-02-16 ZA ZA79726A patent/ZA79726B/xx unknown
- 1979-02-19 CS CS791087A patent/CS207769B2/cs unknown
- 1979-11-01 ES ES485621A patent/ES485621A1/es not_active Expired
- 1979-11-01 ES ES485620A patent/ES485620A0/es active Granted
- 1979-11-01 ES ES485619A patent/ES8502105A1/es not_active Expired
-
1981
- 1981-01-07 AR AR283881A patent/AR225939A1/es active
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