CS207769B2 - Method of preparation of the 9-aminodibenzopyrans - Google Patents

Method of preparation of the 9-aminodibenzopyrans Download PDF

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Publication number
CS207769B2
CS207769B2 CS791087A CS108779A CS207769B2 CS 207769 B2 CS207769 B2 CS 207769B2 CS 791087 A CS791087 A CS 791087A CS 108779 A CS108779 A CS 108779A CS 207769 B2 CS207769 B2 CS 207769B2
Authority
CS
Czechoslovakia
Prior art keywords
formula
pyran
hydroxy
alkanoyl
dimethyl
Prior art date
Application number
CS791087A
Other languages
Czech (cs)
English (en)
Inventor
William A Day
Edward R Lavagnino
Original Assignee
Lilly Co Eli
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lilly Co Eli filed Critical Lilly Co Eli
Priority to CS80410A priority Critical patent/CS207772B2/cs
Priority to CS80408A priority patent/CS207770B2/cs
Priority to CS80409A priority patent/CS207771B2/cs
Publication of CS207769B2 publication Critical patent/CS207769B2/cs

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
    • C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D311/78—Ring systems having three or more relevant rings
    • C07D311/80—Dibenzopyrans; Hydrogenated dibenzopyrans
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/22—Anxiolytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/02—Non-specific cardiovascular stimulants, e.g. drugs for syncope, antihypotensives

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Pain & Pain Management (AREA)
  • Psychiatry (AREA)
  • Rheumatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pyrane Compounds (AREA)
CS791087A 1978-02-17 1979-02-19 Method of preparation of the 9-aminodibenzopyrans CS207769B2 (en)

Priority Applications (3)

Application Number Priority Date Filing Date Title
CS80410A CS207772B2 (cs) 1978-02-17 1980-01-21 Způsob přípravy 9-aminodibcnzopyranů
CS80408A CS207770B2 (cs) 1978-02-17 1980-01-21 Způsob přípravy 9-aminodibenzopyranů
CS80409A CS207771B2 (cs) 1978-02-17 1980-01-21 Způsob přípravy 3-aminodibsnzopyranů

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US05/878,844 US4152450A (en) 1978-02-17 1978-02-17 9-Amino-dibenzopyrans

Publications (1)

Publication Number Publication Date
CS207769B2 true CS207769B2 (en) 1981-08-31

Family

ID=25372961

Family Applications (1)

Application Number Title Priority Date Filing Date
CS791087A CS207769B2 (en) 1978-02-17 1979-02-19 Method of preparation of the 9-aminodibenzopyrans

Country Status (29)

Country Link
US (1) US4152450A (ro)
EP (1) EP0003883B1 (ro)
JP (1) JPS54122278A (ro)
AR (2) AR224359A1 (ro)
AT (1) AT366039B (ro)
AU (1) AU518718B2 (ro)
BE (1) BE873981A (ro)
CA (1) CA1111425A (ro)
CH (1) CH638800A5 (ro)
CS (1) CS207769B2 (ro)
DD (1) DD142190A5 (ro)
DE (1) DE2963797D1 (ro)
DK (1) DK68179A (ro)
ES (4) ES477832A1 (ro)
FI (1) FI790503A (ro)
FR (1) FR2417510A1 (ro)
GB (1) GB2014571B (ro)
GR (1) GR71465B (ro)
HU (1) HU180729B (ro)
IE (1) IE47999B1 (ro)
IL (1) IL56582A0 (ro)
LU (1) LU80922A1 (ro)
NZ (1) NZ189591A (ro)
PH (1) PH14622A (ro)
PL (5) PL118576B1 (ro)
PT (1) PT69202A (ro)
RO (5) RO82375A (ro)
SU (1) SU812177A3 (ro)
ZA (1) ZA79726B (ro)

Families Citing this family (28)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4351833A (en) * 1980-07-28 1982-09-28 Pfizer Inc. 9-Amino-1-hydroxyoctahydrobenzo[c]quinolines and derivatives thereof as analgesics and anti-emetics
US4309545A (en) * 1980-07-28 1982-01-05 Pfizer Inc. Oximino-1-hydroxyoctahydrobenzo[c]quinolines and derivatives thereof
US4841078A (en) * 1982-03-16 1989-06-20 Pfizer Inc. Benzopyrans
US4473704A (en) * 1982-03-16 1984-09-25 Pfizer Inc. Substituted dodecahydrotriphenylenes, decahydro-1H-cyclopenta[1]phenanthrenes, decahydro-1H-pyrido[1,2-f]phenanthridines and decahydropyrrolo[1,2-f]phenanthridines as CNS agents
US4486428A (en) * 1982-03-16 1984-12-04 Pfizer Inc. Bicyclic benzo fused compounds
US4642373A (en) * 1982-03-16 1987-02-10 Pfizer Inc. Substituted dodecahydrotripheylenes, and decahydropyrrolo[1,2-f]phenanthridines as CNS agents
US4863934A (en) * 1982-03-16 1989-09-05 Pfizer Inc. Bicyclic benzo fused pyran compounds used for producing analgesia
US4870084A (en) * 1982-03-16 1989-09-26 Pfizer Inc. Bicyclic benzo fused pyran compounds used for nausea treatment and prevention
US4442089A (en) * 1982-07-06 1984-04-10 E. R. Squibb & Sons, Inc. Method for treating glaucoma with topical or systemic ACE inhibitor compositions
US4680404A (en) * 1983-01-13 1987-07-14 Pfizer Inc. Benzopyrans
US5180736A (en) * 1989-03-23 1993-01-19 Warner-Lambert Company Polycyclic amines useful as cerebrovascular agents
WO1999057106A1 (en) * 1998-05-04 1999-11-11 The University Of Connecticut Novel analgesic and immunomodulatory cannabinoids
US7589220B2 (en) * 1998-06-09 2009-09-15 University Of Connecticut Inhibitors of the anandamide transporter
US7897598B2 (en) * 1998-06-09 2011-03-01 Alexandros Makriyannis Inhibitors of the anandamide transporter
US7161016B1 (en) 1998-11-24 2007-01-09 University Of Connecticut Cannabimimetic lipid amides as useful medications
US7276613B1 (en) 1998-11-24 2007-10-02 University Of Connecticut Retro-anandamides, high affinity and stability cannabinoid receptor ligands
US7119108B1 (en) 1999-10-18 2006-10-10 University Of Connecticut Pyrazole derivatives as cannabinoid receptor antagonists
US6995187B1 (en) 1999-10-18 2006-02-07 University Of Connecticut Peripheral cannabinoid receptor (CB2) selective ligands
US7393842B2 (en) * 2001-08-31 2008-07-01 University Of Connecticut Pyrazole analogs acting on cannabinoid receptors
US6900236B1 (en) 1999-10-18 2005-05-31 University Of Connecticut Cannabimimetic indole derivatives
US8084467B2 (en) * 1999-10-18 2011-12-27 University Of Connecticut Pyrazole derivatives as cannabinoid receptor antagonists
US6943266B1 (en) * 1999-10-18 2005-09-13 University Of Connecticut Bicyclic cannabinoid agonists for the cannabinoid receptor
US7741365B2 (en) * 1999-10-18 2010-06-22 University Of Connecticut Peripheral cannabinoid receptor (CB2) selective ligands
EP1361876A4 (en) * 2001-01-26 2004-03-31 Univ Connecticut NEW CANNABIMIMETIC LIGANDS
JP2005503998A (ja) 2001-01-29 2005-02-10 ユニバーシティ オブ コネチカット 受容体選択性のカンナビミメティックアミノアルキルインドール
US7057076B2 (en) * 2001-07-13 2006-06-06 University Of Connecticut Bicyclic and tricyclic cannabinoids
US7666867B2 (en) * 2001-10-26 2010-02-23 University Of Connecticut Heteroindanes: a new class of potent cannabimimetic ligands
WO2004017922A2 (en) 2002-08-23 2004-03-04 University Of Connecticut Keto cannabinoids with therapeutic indications

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3676462A (en) * 1970-01-08 1972-07-11 Little Inc A 7,8,9,10-TETRAHYDRO (AND 7,8,9,10,11,12-HEXAHYDRO) 6H-DIBENZO {8 b,d{9 {0 PYRANS
US3649650A (en) * 1970-02-13 1972-03-14 Little Inc A Novel derivatives of tetrahydro-cannabinol
AU7612874A (en) * 1973-12-27 1976-06-10 Erba Carlo Spa Benzopyran derivatives

Also Published As

Publication number Publication date
FI790503A (fi) 1979-08-18
RO82370B (ro) 1983-07-30
DE2963797D1 (en) 1982-11-11
ES8502105A1 (es) 1980-07-16
ES8502106A1 (es) 1980-07-16
PL120645B1 (en) 1982-03-31
PL118576B1 (en) 1981-10-31
US4152450A (en) 1979-05-01
RO82370A (ro) 1983-08-03
DD142190A5 (de) 1980-06-11
GB2014571A (en) 1979-08-30
HU180729B (en) 1983-04-29
ES477832A1 (es) 1980-04-01
RO76886A (ro) 1982-02-01
PH14622A (en) 1981-10-12
NZ189591A (en) 1980-10-08
EP0003883B1 (en) 1982-10-06
ATA123979A (de) 1981-07-15
PT69202A (en) 1979-03-01
FR2417510A1 (fr) 1979-09-14
RO82375A (ro) 1983-08-03
PL121009B1 (en) 1982-04-30
CH638800A5 (fr) 1983-10-14
LU80922A1 (fr) 1979-06-18
IE47999B1 (en) 1984-08-22
PL120661B1 (en) 1982-03-31
AU518718B2 (en) 1981-10-15
JPS54122278A (en) 1979-09-21
AT366039B (de) 1982-03-10
PL120658B1 (en) 1982-03-31
BE873981A (fr) 1979-08-07
DK68179A (da) 1979-09-17
IL56582A0 (en) 1979-05-31
ES485621A1 (es) 1980-07-01
ES485619A0 (es) 1980-07-16
ZA79726B (en) 1980-10-29
PL213479A1 (ro) 1980-03-10
RO82376A (ro) 1983-08-03
FR2417510B1 (ro) 1980-08-14
RO82369A (ro) 1983-08-03
ES485620A0 (es) 1980-07-16
EP0003883A1 (en) 1979-09-05
RO82369B (ro) 1983-07-30
SU812177A3 (ru) 1981-03-07
AU4398379A (en) 1979-08-23
GB2014571B (en) 1982-11-17
AR224359A1 (es) 1981-11-30
IE790304L (en) 1979-08-17
AR225939A1 (es) 1982-05-14
RO82376B (ro) 1983-07-30
GR71465B (ro) 1983-05-30
CA1111425A (en) 1981-10-27

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