RO82376B - Procedeu pentru prepararea unor derivati de 9-hidroxiaminodibenzopiran - Google Patents

Procedeu pentru prepararea unor derivati de 9-hidroxiaminodibenzopiran

Info

Publication number
RO82376B
RO82376B RO104557A RO10455779A RO82376B RO 82376 B RO82376 B RO 82376B RO 104557 A RO104557 A RO 104557A RO 10455779 A RO10455779 A RO 10455779A RO 82376 B RO82376 B RO 82376B
Authority
RO
Romania
Prior art keywords
hydroxy
amino
derivatives
preparing
dibenzopyran
Prior art date
Application number
RO104557A
Other languages
English (en)
Other versions
RO82376A (ro
Inventor
William Allen Day
Edward Ralph Lavagnino
Original Assignee
Eli Lilly And Company
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Eli Lilly And Company filed Critical Eli Lilly And Company
Publication of RO82376B publication Critical patent/RO82376B/ro
Publication of RO82376A publication Critical patent/RO82376A/ro

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
    • C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D311/78—Ring systems having three or more relevant rings
    • C07D311/80—Dibenzopyrans; Hydrogenated dibenzopyrans
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/22—Anxiolytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/02—Non-specific cardiovascular stimulants, e.g. drugs for syncope, antihypotensives

Abstract

Inventia se refera la un procedeu pentru prepararea unor derivati de 9-hidroxiaminodibenzopirani cu formula generala I din pag.1 a descrierii, în care R1 reprezinta un atom de hidrogen, R2 reprezinta un radical alchil cu 5...10 atomi de carbon, R3 reprezinta un atom de hidrogen sau un radical metil prin aceea ca derivati cu formula generala II, în care R1, R2 si R3 au semnificatiile mentionate.
RO79104557A 1978-02-17 1979-02-13 Procedeu pentru prepararea unor derivati de 9-hidroxiaminodimenzopirani RO82376A (ro)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US05/878,844 US4152450A (en) 1978-02-17 1978-02-17 9-Amino-dibenzopyrans

Publications (2)

Publication Number Publication Date
RO82376B true RO82376B (ro) 1983-07-30
RO82376A RO82376A (ro) 1983-08-03

Family

ID=25372961

Family Applications (5)

Application Number Title Priority Date Filing Date
RO79104557A RO82376A (ro) 1978-02-17 1979-02-13 Procedeu pentru prepararea unor derivati de 9-hidroxiaminodimenzopirani
RO79104554A RO82369A (ro) 1978-02-17 1979-02-13 Procedeu pentru prepararea unor derivati de 9-aminodibenzoripiran
RO79104556A RO82375A (ro) 1978-02-17 1979-02-13 Procedeu pentru prepararea de derivati ai 9-aminodibenzopiran
RO7996601A RO76886A (ro) 1978-02-17 1979-02-13 Procedeu pentru prepararea unor 9-iminodibenzopirani
RO79104555A RO82370A (ro) 1978-02-17 1979-02-13 Procedeu pentru prepararea unor derivati de 9-aminodibenzopiran

Family Applications After (4)

Application Number Title Priority Date Filing Date
RO79104554A RO82369A (ro) 1978-02-17 1979-02-13 Procedeu pentru prepararea unor derivati de 9-aminodibenzoripiran
RO79104556A RO82375A (ro) 1978-02-17 1979-02-13 Procedeu pentru prepararea de derivati ai 9-aminodibenzopiran
RO7996601A RO76886A (ro) 1978-02-17 1979-02-13 Procedeu pentru prepararea unor 9-iminodibenzopirani
RO79104555A RO82370A (ro) 1978-02-17 1979-02-13 Procedeu pentru prepararea unor derivati de 9-aminodibenzopiran

Country Status (29)

Country Link
US (1) US4152450A (ro)
EP (1) EP0003883B1 (ro)
JP (1) JPS54122278A (ro)
AR (2) AR224359A1 (ro)
AT (1) AT366039B (ro)
AU (1) AU518718B2 (ro)
BE (1) BE873981A (ro)
CA (1) CA1111425A (ro)
CH (1) CH638800A5 (ro)
CS (1) CS207769B2 (ro)
DD (1) DD142190A5 (ro)
DE (1) DE2963797D1 (ro)
DK (1) DK68179A (ro)
ES (4) ES477832A1 (ro)
FI (1) FI790503A (ro)
FR (1) FR2417510A1 (ro)
GB (1) GB2014571B (ro)
GR (1) GR71465B (ro)
HU (1) HU180729B (ro)
IE (1) IE47999B1 (ro)
IL (1) IL56582A0 (ro)
LU (1) LU80922A1 (ro)
NZ (1) NZ189591A (ro)
PH (1) PH14622A (ro)
PL (5) PL121009B1 (ro)
PT (1) PT69202A (ro)
RO (5) RO82376A (ro)
SU (1) SU812177A3 (ro)
ZA (1) ZA79726B (ro)

Families Citing this family (28)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4351833A (en) * 1980-07-28 1982-09-28 Pfizer Inc. 9-Amino-1-hydroxyoctahydrobenzo[c]quinolines and derivatives thereof as analgesics and anti-emetics
US4309545A (en) * 1980-07-28 1982-01-05 Pfizer Inc. Oximino-1-hydroxyoctahydrobenzo[c]quinolines and derivatives thereof
US4486428A (en) * 1982-03-16 1984-12-04 Pfizer Inc. Bicyclic benzo fused compounds
US4870084A (en) * 1982-03-16 1989-09-26 Pfizer Inc. Bicyclic benzo fused pyran compounds used for nausea treatment and prevention
US4863934A (en) * 1982-03-16 1989-09-05 Pfizer Inc. Bicyclic benzo fused pyran compounds used for producing analgesia
US4642373A (en) * 1982-03-16 1987-02-10 Pfizer Inc. Substituted dodecahydrotripheylenes, and decahydropyrrolo[1,2-f]phenanthridines as CNS agents
US4841078A (en) * 1982-03-16 1989-06-20 Pfizer Inc. Benzopyrans
US4473704A (en) * 1982-03-16 1984-09-25 Pfizer Inc. Substituted dodecahydrotriphenylenes, decahydro-1H-cyclopenta[1]phenanthrenes, decahydro-1H-pyrido[1,2-f]phenanthridines and decahydropyrrolo[1,2-f]phenanthridines as CNS agents
US4442089A (en) * 1982-07-06 1984-04-10 E. R. Squibb & Sons, Inc. Method for treating glaucoma with topical or systemic ACE inhibitor compositions
US4680404A (en) * 1983-01-13 1987-07-14 Pfizer Inc. Benzopyrans
US5180736A (en) * 1989-03-23 1993-01-19 Warner-Lambert Company Polycyclic amines useful as cerebrovascular agents
ATE247097T1 (de) * 1998-05-04 2003-08-15 Univ Connecticut Analgetische und immunomodulierende cannabinoiden
US7897598B2 (en) * 1998-06-09 2011-03-01 Alexandros Makriyannis Inhibitors of the anandamide transporter
US7589220B2 (en) * 1998-06-09 2009-09-15 University Of Connecticut Inhibitors of the anandamide transporter
US7161016B1 (en) 1998-11-24 2007-01-09 University Of Connecticut Cannabimimetic lipid amides as useful medications
US7276613B1 (en) 1998-11-24 2007-10-02 University Of Connecticut Retro-anandamides, high affinity and stability cannabinoid receptor ligands
US6943266B1 (en) * 1999-10-18 2005-09-13 University Of Connecticut Bicyclic cannabinoid agonists for the cannabinoid receptor
US8084467B2 (en) * 1999-10-18 2011-12-27 University Of Connecticut Pyrazole derivatives as cannabinoid receptor antagonists
US7393842B2 (en) * 2001-08-31 2008-07-01 University Of Connecticut Pyrazole analogs acting on cannabinoid receptors
US7741365B2 (en) * 1999-10-18 2010-06-22 University Of Connecticut Peripheral cannabinoid receptor (CB2) selective ligands
US6900236B1 (en) * 1999-10-18 2005-05-31 University Of Connecticut Cannabimimetic indole derivatives
US7119108B1 (en) 1999-10-18 2006-10-10 University Of Connecticut Pyrazole derivatives as cannabinoid receptor antagonists
MXPA02005103A (es) 1999-10-18 2003-09-25 Alexipharma Inc Ligandos selectivos del receptor de canabinoide (cb2) perifericos.
JP2004532185A (ja) * 2001-01-26 2004-10-21 ユニバーシティ オブ コネチカット 新規なカンナビミメティックリガンド
US7173027B2 (en) 2001-01-29 2007-02-06 University Of Connecticut Receptor selective cannabimimetic aminoalkylindoles
EP1414775B1 (en) 2001-07-13 2012-12-19 The University of Connecticut Bicyclic cannabinoid
EP1448557A4 (en) * 2001-10-26 2005-02-02 Univ Connecticut HETEROINDANE: A NEW CLASS OF HIGH-ACTIVITY CANNABIMIMETIC LIGANDS
JP2006511460A (ja) 2002-08-23 2006-04-06 ユニバーシティ オブ コネチカット 治療適応を持つケトカンナビノイド

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3676462A (en) * 1970-01-08 1972-07-11 Little Inc A 7,8,9,10-TETRAHYDRO (AND 7,8,9,10,11,12-HEXAHYDRO) 6H-DIBENZO {8 b,d{9 {0 PYRANS
US3649650A (en) * 1970-02-13 1972-03-14 Little Inc A Novel derivatives of tetrahydro-cannabinol
AU7612874A (en) * 1973-12-27 1976-06-10 Erba Carlo Spa Benzopyran derivatives

Also Published As

Publication number Publication date
FR2417510A1 (fr) 1979-09-14
PL120661B1 (en) 1982-03-31
PL118576B1 (en) 1981-10-31
AT366039B (de) 1982-03-10
JPS54122278A (en) 1979-09-21
RO82369A (ro) 1983-08-03
CS207769B2 (en) 1981-08-31
ES8502106A1 (es) 1980-07-16
RO76886A (ro) 1982-02-01
IE790304L (en) 1979-08-17
DD142190A5 (de) 1980-06-11
FR2417510B1 (ro) 1980-08-14
PL213479A1 (ro) 1980-03-10
RO82370B (ro) 1983-07-30
GB2014571A (en) 1979-08-30
US4152450A (en) 1979-05-01
PL121009B1 (en) 1982-04-30
FI790503A (fi) 1979-08-18
CH638800A5 (fr) 1983-10-14
PH14622A (en) 1981-10-12
EP0003883A1 (en) 1979-09-05
ES485620A0 (es) 1980-07-16
ES485621A1 (es) 1980-07-01
ES8502105A1 (es) 1980-07-16
ZA79726B (en) 1980-10-29
BE873981A (fr) 1979-08-07
DK68179A (da) 1979-09-17
AR225939A1 (es) 1982-05-14
RO82370A (ro) 1983-08-03
ES477832A1 (es) 1980-04-01
RO82375A (ro) 1983-08-03
CA1111425A (en) 1981-10-27
IL56582A0 (en) 1979-05-31
LU80922A1 (fr) 1979-06-18
IE47999B1 (en) 1984-08-22
ATA123979A (de) 1981-07-15
PL120658B1 (en) 1982-03-31
RO82369B (ro) 1983-07-30
GB2014571B (en) 1982-11-17
PL120645B1 (en) 1982-03-31
SU812177A3 (ru) 1981-03-07
EP0003883B1 (en) 1982-10-06
GR71465B (ro) 1983-05-30
DE2963797D1 (en) 1982-11-11
AU518718B2 (en) 1981-10-15
ES485619A0 (es) 1980-07-16
HU180729B (en) 1983-04-29
RO82376A (ro) 1983-08-03
AR224359A1 (es) 1981-11-30
AU4398379A (en) 1979-08-23
NZ189591A (en) 1980-10-08
PT69202A (en) 1979-03-01

Similar Documents

Publication Publication Date Title
RO82376B (ro) Procedeu pentru prepararea unor derivati de 9-hidroxiaminodibenzopiran
RO84802B (ro) Procedeu pentru obtinerea unor (1-aril-ciclobutil)-alchilamine
RO81173B (ro) Procedeu pentru prepararea unor derivati de delta 2-1, 2, 4-triazolin-5-ona
ES455294A1 (es) Un procedimiento de preparacion de una fenilamidina sustituida.
RO84317B (ro) Procedeu de preparare a unor derivati de difenileter cu activitate erbicida
RO82173B (ro) Procedeu de obtinere a unor derivati de flavan
ES394369A1 (es) Procedimiento para la preparacion de derivados de la isoin-dolina.
RO80925B (ro) Procedeu pentru prepararea unor derivati de nitrotiofen
RO92200B (ro) Procedeu pentru prepararea unor s-benzilcarbamati
RO72835B (ro) Procedeu pentru prepararea unor derivati ai xantinei bazic substituiti
ES462304A1 (es) Un procedimiento para la preparacion de nuevos derivados de urazol 1,2,4-sustituidos.
RO84583B (ro) Procedeu pentru prepararea unor derivati de piranona
RO72831B (ro) Procedeu pentru prepararea unor fenilpiperazine
RO82375B1 (ro) Procedeu pentru prepararea unor derivati de 9-amino-dibenzopiran
RO72834B (ro) Procedeu de obtinere a unor derivati ai acizilor (5-alchilureido-1, 3, 4-tiadiazol-2-il-sulfonil)-acetici
RO81226B (ro) Procedeu pentru prepararea unor derivati de 5(3)-hidroxipirazol
ES469896A1 (es) Procedimiento para la obtencion de derivados de la hidroxi-4tiazolinationa-2
ES434151A1 (es) Procedimiento para la preparacion de 4,5-difeniltiazoles 2-sustituidos.
ES540260A0 (es) Procedimiento para preparar derivados de 2-alcoxiaminosulfo-nilbencenosulfonilurea
RO82013B (ro) Procedeu pentru prepararea unor derivati de carbostiril
RO82380B (ro) Procedeu pentru prepararea unor derivati de benzo[b] ciclohepta[d]piran
ES484422A1 (es) Un procedimiento para la isomerizacion de un 2-ciano-3-aza- biciclo (3.1.0) hexano cis o trans
RO81210B (ro) Procedeu pentru prepararea unor derivati de 1, 2, 4-oxadiazina
GB1290695A (ro)
RO82505B (ro) Procedeu pentru prepararea unor derivati de chinoxalinil-1, 4-dioxizi