FR2428047A1 - Arylalkyl- et aryloxyalkyl- phosphonates, leur preparation et leur utilisation therapeutique - Google Patents

Arylalkyl- et aryloxyalkyl- phosphonates, leur preparation et leur utilisation therapeutique

Info

Publication number
FR2428047A1
FR2428047A1 FR7913632A FR7913632A FR2428047A1 FR 2428047 A1 FR2428047 A1 FR 2428047A1 FR 7913632 A FR7913632 A FR 7913632A FR 7913632 A FR7913632 A FR 7913632A FR 2428047 A1 FR2428047 A1 FR 2428047A1
Authority
FR
France
Prior art keywords
arylalkyl
aryloxyalkyl
phosphonates
preparation
therapeutic use
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
FR7913632A
Other languages
English (en)
Other versions
FR2428047B1 (fr
Inventor
Guy Dominic Diana
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
STWB Inc
Original Assignee
Sterling Drug Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sterling Drug Inc filed Critical Sterling Drug Inc
Publication of FR2428047A1 publication Critical patent/FR2428047A1/fr
Application granted granted Critical
Publication of FR2428047B1 publication Critical patent/FR2428047B1/fr
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic System
    • C07F9/02—Phosphorus compounds
    • C07F9/28—Phosphorus compounds with one or more P—C bonds
    • C07F9/38—Phosphonic acids RP(=O)(OH)2; Thiophosphonic acids, i.e. RP(=X)(XH)2 (X = S, Se)
    • C07F9/40—Esters thereof
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic System
    • C07F9/02—Phosphorus compounds
    • C07F9/28—Phosphorus compounds with one or more P—C bonds
    • C07F9/38—Phosphonic acids RP(=O)(OH)2; Thiophosphonic acids, i.e. RP(=X)(XH)2 (X = S, Se)
    • C07F9/40—Esters thereof
    • C07F9/4003—Esters thereof the acid moiety containing a substituent or a structure which is considered as characteristic
    • C07F9/4056—Esters of arylalkanephosphonic acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic System
    • C07F9/02—Phosphorus compounds
    • C07F9/28—Phosphorus compounds with one or more P—C bonds
    • C07F9/38—Phosphonic acids RP(=O)(OH)2; Thiophosphonic acids, i.e. RP(=X)(XH)2 (X = S, Se)
    • C07F9/40—Esters thereof
    • C07F9/4003—Esters thereof the acid moiety containing a substituent or a structure which is considered as characteristic
    • C07F9/4006—Esters of acyclic acids which can have further substituents on alkyl

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Oncology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Communicable Diseases (AREA)
  • Virology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

L'invention concerne des arylalkyl- et aryloxyalkyl-phospho-nates de formule :
FR7913632A 1978-06-05 1979-05-29 Arylalkyl- et aryloxyalkyl- phosphonates, leur preparation et leur utilisation therapeutique Granted FR2428047A1 (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US05/912,502 US4182759A (en) 1978-06-05 1978-06-05 Arylalkyl and aryloxyalkyl phosphonates and use as antiviral agents

Publications (2)

Publication Number Publication Date
FR2428047A1 true FR2428047A1 (fr) 1980-01-04
FR2428047B1 FR2428047B1 (fr) 1984-08-17

Family

ID=25432033

Family Applications (1)

Application Number Title Priority Date Filing Date
FR7913632A Granted FR2428047A1 (fr) 1978-06-05 1979-05-29 Arylalkyl- et aryloxyalkyl- phosphonates, leur preparation et leur utilisation therapeutique

Country Status (27)

Country Link
US (1) US4182759A (fr)
JP (1) JPS54160348A (fr)
KR (1) KR840002462B1 (fr)
AR (1) AR223343A1 (fr)
AT (1) AT373897B (fr)
AU (1) AU528266B2 (fr)
BE (1) BE876680A (fr)
CA (1) CA1108176A (fr)
CH (1) CH641188A5 (fr)
DE (1) DE2922054A1 (fr)
DK (1) DK223579A (fr)
ES (2) ES481227A1 (fr)
FI (1) FI66009C (fr)
FR (1) FR2428047A1 (fr)
GB (1) GB2022589B (fr)
IE (1) IE48334B1 (fr)
IL (1) IL57300A (fr)
IT (1) IT1203687B (fr)
LU (1) LU81350A1 (fr)
MX (1) MX6013E (fr)
NL (1) NL7904265A (fr)
NO (1) NO791770L (fr)
NZ (1) NZ190460A (fr)
PH (2) PH14734A (fr)
PT (1) PT69693A (fr)
SE (1) SE7904687L (fr)
ZA (1) ZA792447B (fr)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB2043073B (en) * 1979-02-13 1983-05-11 Symphar Sa Mono-and diphosphonate compounds
US4556520A (en) * 1982-10-08 1985-12-03 Zoecon Corporation 2-Nitro(cyano)phenyloxy(thio)alkyl phosphinates or phosphonates
DE4003054A1 (de) * 1990-02-02 1991-08-08 Hoechst Ag Verwendung von benzylphosphonsaeurederivaten zur behandlung von durch viren verursachte krankheiten
BR112012008050A2 (pt) * 2009-08-27 2017-07-04 Epiphany Biosciences Inc fosfonatos de nucleosídeo e análogos.

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2934507A (en) * 1954-06-18 1960-04-26 Monsanto Chemicals Polyvinyl chloride resins stabilized with mixtures of phosphonate esters, epoxy compounds and metallic salts of fatty acids
US3917718A (en) * 1972-06-22 1975-11-04 Sterling Drug Inc Cyclopropyl carbinol derivatives
US4031246A (en) * 1973-07-23 1977-06-21 Sterling Drug Inc. Aryloxyalkyl diketones

Also Published As

Publication number Publication date
ES481227A1 (es) 1980-09-01
AU528266B2 (en) 1983-04-21
AR223343A1 (es) 1981-08-14
FR2428047B1 (fr) 1984-08-17
ES489590A0 (es) 1981-02-16
CA1108176A (fr) 1981-09-01
IE48334B1 (en) 1984-12-12
AU4724979A (en) 1979-12-13
US4182759A (en) 1980-01-08
IT7923000A0 (it) 1979-05-25
PT69693A (en) 1979-06-01
GB2022589B (en) 1982-10-13
MX6013E (es) 1984-09-24
AT373897B (de) 1984-02-27
KR840002462B1 (ko) 1984-12-29
CH641188A5 (fr) 1984-02-15
DK223579A (da) 1979-12-06
JPS54160348A (en) 1979-12-19
IL57300A (en) 1983-06-15
IE790945L (en) 1979-12-05
KR830001644A (ko) 1983-05-18
US4182759B1 (fr) 1984-12-18
BE876680A (fr) 1979-11-30
NZ190460A (en) 1981-07-13
NL7904265A (nl) 1979-12-07
GB2022589A (en) 1979-12-19
PH15469A (en) 1983-01-24
FI66009C (fi) 1984-08-10
FI791718A (fi) 1979-12-06
NO791770L (no) 1979-12-06
ZA792447B (en) 1980-06-25
SE7904687L (sv) 1979-12-06
PH14734A (en) 1981-11-19
LU81350A1 (fr) 1979-12-07
IT1203687B (it) 1989-02-15
FI66009B (fi) 1984-04-30
ES8103110A1 (es) 1981-02-16
ATA401779A (de) 1983-07-15
DE2922054A1 (de) 1979-12-06
IL57300A0 (en) 1979-09-30

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