DE2707565A1 - Syn-isomere von 3,7-disubstituierten-3-cephem-4-carbonsaeureverbindungen, verfahren zu ihrer herstellung und sie enthaltende pharmazeutische mittel - Google Patents
Syn-isomere von 3,7-disubstituierten-3-cephem-4-carbonsaeureverbindungen, verfahren zu ihrer herstellung und sie enthaltende pharmazeutische mittelInfo
- Publication number
- DE2707565A1 DE2707565A1 DE19772707565 DE2707565A DE2707565A1 DE 2707565 A1 DE2707565 A1 DE 2707565A1 DE 19772707565 DE19772707565 DE 19772707565 DE 2707565 A DE2707565 A DE 2707565A DE 2707565 A1 DE2707565 A1 DE 2707565A1
- Authority
- DE
- Germany
- Prior art keywords
- group
- formula
- compounds according
- amino
- acetamido
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
- C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
- C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
- C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
- C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D277/32—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D277/38—Nitrogen atoms
- C07D277/44—Acylated amino or imino radicals
- C07D277/48—Acylated amino or imino radicals by radicals derived from carbonic acid, or sulfur or nitrogen analogues thereof, e.g. carbonylguanidines
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
- C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
- C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D277/587—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with aliphatic hydrocarbon radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms, said aliphatic radicals being substituted in the alpha-position to the ring by a hetero atom, e.g. with m >= 0, Z being a singly or a doubly bound hetero atom
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
- C07D333/02—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
- C07D333/04—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
- C07D333/06—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to the ring carbon atoms
- C07D333/14—Radicals substituted by singly bound hetero atoms other than halogen
- C07D333/16—Radicals substituted by singly bound hetero atoms other than halogen by oxygen atoms
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P20/00—Technologies relating to chemical industry
- Y02P20/50—Improvements relating to the production of bulk chemicals
- Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Cephalosporin Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GB14916/76A GB1576625A (en) | 1976-04-12 | 1976-04-12 | Syn isomer 3,7 disubstituted 3 cephem 4 carboxylic acid compounds and processes for the preparation thereof |
GB2349076 | 1976-06-07 | ||
JP51125826A JPS5941995B2 (ja) | 1976-04-12 | 1976-10-19 | 3,7−ジ置換−3−セフエム−4−カルボン酸化合物およびその塩類およびそれらの製造方法 |
Publications (2)
Publication Number | Publication Date |
---|---|
DE2707565A1 true DE2707565A1 (de) | 1978-02-23 |
DE2707565C2 DE2707565C2 (no) | 1988-06-30 |
Family
ID=27257189
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE19772707565 Granted DE2707565A1 (de) | 1976-04-12 | 1977-02-22 | Syn-isomere von 3,7-disubstituierten-3-cephem-4-carbonsaeureverbindungen, verfahren zu ihrer herstellung und sie enthaltende pharmazeutische mittel |
Country Status (13)
Country | Link |
---|---|
AR (2) | AR227864A1 (no) |
AT (1) | AT358728B (no) |
CA (1) | CA1337522C (no) |
CH (2) | CH638532A5 (no) |
DE (1) | DE2707565A1 (no) |
DK (1) | DK162391C (no) |
ES (7) | ES457191A1 (no) |
FR (1) | FR2348219A1 (no) |
HU (1) | HU177441B (no) |
IE (1) | IE45597B1 (no) |
MX (1) | MX4985E (no) |
NL (1) | NL191259C (no) |
SE (2) | SE443981B (no) |
Cited By (14)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE2715385A1 (de) * | 1976-04-14 | 1977-11-10 | Takeda Chemical Industries Ltd | Cephalosporinderivate, verfahren zu ihrer herstellung und sie enthaltende arzneimittel |
DE2806226A1 (de) * | 1977-02-18 | 1978-08-24 | Roussel Uclaf | Oximderivate der 3-thiadiazolylthiomethyl-7-aminothiazolyl-acetamido- cephalosporansaeure, ihr herstellungsverfahren sowie pharmazeutische zusammensetzungen |
DE2810922A1 (de) | 1977-03-14 | 1978-09-21 | Fujisawa Pharmaceutical Co | Neue cephem- und cepham-verbindungen, verfahren zu ihrer herstellung und sie enthaltende arzneimittel |
DE2812625A1 (de) * | 1977-03-25 | 1978-09-28 | Roussel Uclaf | Oximderivate der 3-acetoxymethyl-7- aminothiazolyl-acetamido-cephalosporansaeure, ihre herstellung und pharmazeutische mittel |
DE2716707A1 (de) * | 1977-04-02 | 1978-10-19 | Hoechst Ag | Cephemderivate und verfahren zu ihrer herstellung |
DE2900961A1 (de) * | 1978-01-13 | 1979-07-19 | Takeda Chemical Industries Ltd | Cephalosporine und verfahren zu deren herstellung |
DE2912829A1 (de) * | 1978-03-31 | 1979-10-04 | Roussel Uclaf | O-substituierte oximderivate der 7-aminotiaoyl-acetamido-cephalosporansaeure, ihre herstellung und pharmazeutische zusammensetzungen |
EP0005830A1 (de) | 1978-05-30 | 1979-12-12 | F. HOFFMANN-LA ROCHE & CO. Aktiengesellschaft | Cephalosporinderivate, deren Herstellung und die entsprechenden pharmazeutischen Präparate |
DE2935232A1 (de) * | 1978-09-04 | 1980-03-13 | Fujisawa Pharmaceutical Co | 3,7-disubstituierte-3-cephem-4- carbonsaeure-verbindungen, verfahren zu ihrer herstellung und sie enthaltende pharmazeutische mittel |
DE2936434A1 (de) * | 1978-09-11 | 1980-03-20 | Fujisawa Pharmaceutical Co | Cephemverbindungen, verfahren zu ihrer herstellung, sie enthaltende pharmazeutische mittel sowie ihre therapeutische verwendung fuer die behandlung von infektionserkrankungen bei menschen und tieren |
EP0010667A1 (en) * | 1978-10-17 | 1980-05-14 | Fujisawa Pharmaceutical Co., Ltd. | Cepham compounds, pharmaceutical compositions containing them and processes for the preparation thereof and of known cephem compounds |
DE2945248A1 (de) * | 1978-11-13 | 1980-05-22 | Fujisawa Pharmaceutical Co | Cephem-verbindungen, verfahren zu ihrer herstellung und sie enthaltende antibakterielle pharmazeutische mittel |
DE3003724A1 (de) * | 1979-02-09 | 1980-08-21 | Roussel Uclaf | Neue oximderivate der 7-aminothiazolylacetamidocephalosporansaeure, ihre herstellung und verwendung |
DE3027281A1 (de) * | 1979-07-19 | 1981-02-12 | Roussel Uclaf | Alkyloximderivate der 7-(2-amino-4thiazolyl)-acetamido-cephalosporansaeure, ihre herstellung, neue zwischenprodukte sowie ihre anwendung als medikamente und in pharmazeutischen mitteln |
Families Citing this family (16)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3192167A (en) * | 1962-09-20 | 1965-06-29 | Ogawa Abiko | Low pressure liquid vaporizer which is electrically heated |
FR2399418A1 (fr) * | 1977-03-14 | 1979-03-02 | Fujisawa Pharmaceutical Co | Procede de preparation d'acides iminoacetiques et nouveaux produits ainsi obtenus, utilises pour la synthese d'acides cepham- ou cephem-carboxyliques |
FR2553770B2 (fr) * | 1978-03-31 | 1986-03-14 | Roussel Uclaf | Nouveaux produits derives de l'acide 2(2-amino thiazol-4-yl) 2-alcoxy-imino acetique substitues sur l'oxime et leur procede de preparation |
FR2421907A1 (fr) * | 1978-04-07 | 1979-11-02 | Roussel Uclaf | Nouvelles cephalosporines derivees de l'acide 7-/2-(2-amino 4-thiazolyl)2-(carboxymethoxyimino/acetamido 3-substitue cephalosporanique, leur procede de preparation et leur application comme medicaments |
FR2438051A2 (fr) * | 1978-10-05 | 1980-04-30 | Roussel Uclaf | Nouvelles oximes derivees de l'acide 3-azidomethyl 7-amino thiazolyl acetamido cephalosporanique, leur procede de preparation et leur application comme medicaments |
US4284631A (en) * | 1978-07-31 | 1981-08-18 | Fujisawa Pharmaceutical Co., Ltd. | 7-Substituted cephem compounds and pharmaceutical antibacterial compositions containing them |
FR2453161A1 (fr) * | 1978-08-31 | 1980-10-31 | Fujisawa Pharmaceutical Co | Procede de preparation de derives d'acide thiazolylacetique et nouveaux produits ainsi obtenus |
FR2462439A1 (fr) * | 1979-07-26 | 1981-02-13 | Roussel Uclaf | Nouveau procede de preparation de produits derives de l'acide 7-/(2-aryl) 2-hydroxyimino acetamido/cephalosporanique |
IL61458A0 (en) * | 1979-12-07 | 1980-12-31 | Erba Farmitalia | N-substituted thiazolyl derivatives of oximino-substituted cephalosporins, their preparation and pharmalceutical compositions containing them |
FR2506307A1 (fr) * | 1981-05-22 | 1982-11-26 | Roussel Uclaf | Nouveaux derives substitues de l'acide 2-(2-amino 4-thiazolyl) 2-hydroxyimino acetique et leur procede de preparation |
US4426528A (en) * | 1982-04-01 | 1984-01-17 | Eli Lilly And Company | Purification of syn-(2-aminothiazol-4-yl)methoxyimino)acetic acid |
FR2532936A1 (fr) * | 1982-09-13 | 1984-03-16 | Roussel Uclaf | Nouveaux derives de l'acide 2-amino-thiazolyl-4-yl acetique comportant une fonction oxime substituee et leur procede de preparation |
GB8324152D0 (en) * | 1983-09-09 | 1983-10-12 | Glaxo Group Ltd | Chemical process |
IT8448798A0 (it) * | 1983-09-12 | 1984-09-05 | Biochemie Gmbh | Procedimento per la preparazione di antibiotici del tipo cefalosporina |
GB2161476B (en) * | 1984-05-25 | 1988-01-27 | Toyama Chemical Co Ltd | 2-aminothiazolyl-2-methoxyimino acetamides and their use in preparing cephalosporins |
ATE110386T1 (de) * | 1986-04-14 | 1994-09-15 | Banyu Pharma Co Ltd | Cephalosporinderivate, verfahren zu ihrer herstellung und antibakterielle präparate. |
Citations (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE2223375A1 (de) * | 1971-05-14 | 1972-11-23 | Glaxo Lab Ltd | Antibiotika und Verfahren zu ihrer Herstellung |
DE2461478A1 (de) * | 1973-12-25 | 1976-02-26 | Takeda Chemical Industries Ltd | Neue 7-(thiazolin-4-yl-acetamido)- cephalosporinderivate, verfahren zur herstellung derselben und diese enthaltende pharmazeutische mittel |
DE2604207A1 (de) * | 1975-02-04 | 1976-08-05 | Fujisawa Pharmaceutical Co | 7-(alpha, alpha-disubstituierte- acetamido)-3-substituierte-3-cephem- 4-carbonsaeuren |
DE2556736C2 (de) * | 1974-12-19 | 1982-02-11 | Takeda Chemical Industries, Ltd., Osaka | Cephemverbindungen und sie enthaltende Arzneimittel |
DE2702501C2 (de) * | 1976-01-23 | 1982-11-18 | Roussel-Uclaf, 75007 Paris | Oximderivate von 7-Aminothiazolylacetamidocephalosporansäure (syn-Isomere), ihre Herstellung und pharmazeutische Zusammensetzungen |
DE2713272C2 (de) * | 1976-03-25 | 1983-01-20 | Roussel-Uclaf, 75007 Paris | Derivate der 7-Aminothiazolyl-acetamido-cephalosporansäure, ihre Herstellung und pharmazeutische Zusammensetzungen |
DE2760123C2 (de) * | 1976-01-23 | 1986-04-30 | Roussel-Uclaf, Paris | 7-Aminothiazolyl-syn-oxyiminoacetamidocephalosporansäuren, ihre Herstellung und sie enthaltende pharmazeutische Zusammensetzungen |
Family Cites Families (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR2346014A1 (fr) * | 1976-01-23 | 1977-10-28 | Roussel Uclaf | Nouvelles oximes derivees de l'acide 7-amino thiazolyl acetamido cephalosporanique, leur procede de preparation et leur application comme medicaments |
DE2760484C2 (no) * | 1976-04-14 | 1992-12-03 | Takeda Chemical Industries, Ltd., Osaka, Jp |
-
1977
- 1977-02-21 DK DK075077A patent/DK162391C/da active
- 1977-02-22 DE DE19772707565 patent/DE2707565A1/de active Granted
- 1977-02-22 SE SE7701964A patent/SE443981B/xx not_active IP Right Cessation
- 1977-02-23 CA CA000272430A patent/CA1337522C/en not_active Expired - Lifetime
- 1977-02-25 CH CH244777A patent/CH638532A5/de not_active IP Right Cessation
- 1977-02-28 HU HU77FU348A patent/HU177441B/hu unknown
- 1977-03-01 IE IE440/77A patent/IE45597B1/en not_active IP Right Cessation
- 1977-03-02 AT AT138477A patent/AT358728B/de not_active IP Right Cessation
- 1977-03-10 FR FR7707173A patent/FR2348219A1/fr active Granted
- 1977-03-25 ES ES457191A patent/ES457191A1/es not_active Expired
- 1977-04-11 MX MX775624U patent/MX4985E/es unknown
- 1977-04-12 NL NL7703969A patent/NL191259C/xx not_active IP Right Cessation
- 1977-04-20 AR AR257178A patent/AR227864A1/es active
-
1978
- 1978-03-27 AR AR271541A patent/AR223143A1/es active
- 1978-04-12 ES ES468719A patent/ES468719A1/es not_active Expired
-
1979
- 1979-02-15 ES ES477741A patent/ES477741A1/es not_active Expired
- 1979-10-16 ES ES485061A patent/ES485061A1/es not_active Expired
- 1979-10-16 ES ES485062A patent/ES485062A1/es not_active Expired
- 1979-10-16 ES ES485063A patent/ES485063A1/es not_active Expired
- 1979-10-16 ES ES485064A patent/ES485064A1/es not_active Expired
-
1983
- 1983-07-26 CH CH409583A patent/CH643557A5/de not_active IP Right Cessation
- 1983-08-17 SE SE8304465A patent/SE457351B/sv not_active IP Right Cessation
Patent Citations (10)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE2223375A1 (de) * | 1971-05-14 | 1972-11-23 | Glaxo Lab Ltd | Antibiotika und Verfahren zu ihrer Herstellung |
DE2461478A1 (de) * | 1973-12-25 | 1976-02-26 | Takeda Chemical Industries Ltd | Neue 7-(thiazolin-4-yl-acetamido)- cephalosporinderivate, verfahren zur herstellung derselben und diese enthaltende pharmazeutische mittel |
DE2556736C2 (de) * | 1974-12-19 | 1982-02-11 | Takeda Chemical Industries, Ltd., Osaka | Cephemverbindungen und sie enthaltende Arzneimittel |
DE2560398C2 (de) * | 1974-12-19 | 1983-09-29 | Takeda Chemical Industries, Ltd., Osaka | 2-Amino-thiazol-4-yl-essigsäure-Derivate und Verfahren zu deren Herstellung |
DE2604207A1 (de) * | 1975-02-04 | 1976-08-05 | Fujisawa Pharmaceutical Co | 7-(alpha, alpha-disubstituierte- acetamido)-3-substituierte-3-cephem- 4-carbonsaeuren |
DE2702501C2 (de) * | 1976-01-23 | 1982-11-18 | Roussel-Uclaf, 75007 Paris | Oximderivate von 7-Aminothiazolylacetamidocephalosporansäure (syn-Isomere), ihre Herstellung und pharmazeutische Zusammensetzungen |
DE2759895C2 (de) * | 1976-01-23 | 1986-01-16 | Roussel-Uclaf, Paris | Verwendung von syn-Alkoxyiminoderivaten von Aminothiazolylessigsäuren zur Herstellung entsprechender 7-Aminothiazolyl-syn-alkoxyiminoacetamidocephalosporansäuren |
DE2760123C2 (de) * | 1976-01-23 | 1986-04-30 | Roussel-Uclaf, Paris | 7-Aminothiazolyl-syn-oxyiminoacetamidocephalosporansäuren, ihre Herstellung und sie enthaltende pharmazeutische Zusammensetzungen |
DE2713272C2 (de) * | 1976-03-25 | 1983-01-20 | Roussel-Uclaf, 75007 Paris | Derivate der 7-Aminothiazolyl-acetamido-cephalosporansäure, ihre Herstellung und pharmazeutische Zusammensetzungen |
DE2760156C2 (no) * | 1976-03-25 | 1987-08-27 | Roussel-Uclaf, Paris, Fr |
Non-Patent Citations (5)
Title |
---|
J. Heterocyclic Chem. 15, 1978, 1295-1298 |
J. Med. Chem. 22, 1979, 1214-1218 |
Liebigs Ann. Chem. 722, 1969, 222-224 |
Protective Groups in Organic Synthesis, T.W., GREENE, Harvard University, Wiley 1981, P. 208, 209 |
Tetrahedron Lett. 26, 1973, 2389-2392 |
Cited By (18)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE2715385A1 (de) * | 1976-04-14 | 1977-11-10 | Takeda Chemical Industries Ltd | Cephalosporinderivate, verfahren zu ihrer herstellung und sie enthaltende arzneimittel |
DE2806226A1 (de) * | 1977-02-18 | 1978-08-24 | Roussel Uclaf | Oximderivate der 3-thiadiazolylthiomethyl-7-aminothiazolyl-acetamido- cephalosporansaeure, ihr herstellungsverfahren sowie pharmazeutische zusammensetzungen |
DE2810922A1 (de) | 1977-03-14 | 1978-09-21 | Fujisawa Pharmaceutical Co | Neue cephem- und cepham-verbindungen, verfahren zu ihrer herstellung und sie enthaltende arzneimittel |
DE2858771C2 (no) * | 1977-03-25 | 1990-09-06 | Roussel-Uclaf S.A., Paris, Fr | |
DE2812625A1 (de) * | 1977-03-25 | 1978-09-28 | Roussel Uclaf | Oximderivate der 3-acetoxymethyl-7- aminothiazolyl-acetamido-cephalosporansaeure, ihre herstellung und pharmazeutische mittel |
DE2716707A1 (de) * | 1977-04-02 | 1978-10-19 | Hoechst Ag | Cephemderivate und verfahren zu ihrer herstellung |
DE2714880A1 (de) * | 1977-04-02 | 1978-10-26 | Hoechst Ag | Cephemderivate und verfahren zu ihrer herstellung |
DE2900961A1 (de) * | 1978-01-13 | 1979-07-19 | Takeda Chemical Industries Ltd | Cephalosporine und verfahren zu deren herstellung |
DE2912829A1 (de) * | 1978-03-31 | 1979-10-04 | Roussel Uclaf | O-substituierte oximderivate der 7-aminotiaoyl-acetamido-cephalosporansaeure, ihre herstellung und pharmazeutische zusammensetzungen |
EP0005830A1 (de) | 1978-05-30 | 1979-12-12 | F. HOFFMANN-LA ROCHE & CO. Aktiengesellschaft | Cephalosporinderivate, deren Herstellung und die entsprechenden pharmazeutischen Präparate |
EP0045525A2 (de) * | 1978-05-30 | 1982-02-10 | F. HOFFMANN-LA ROCHE & CO. Aktiengesellschaft | Cephalosporinderivate und deren Herstellung |
EP0045525B1 (de) * | 1978-05-30 | 1984-04-25 | F. HOFFMANN-LA ROCHE & CO. Aktiengesellschaft | Cephalosporinderivate und deren Herstellung |
DE2935232A1 (de) * | 1978-09-04 | 1980-03-13 | Fujisawa Pharmaceutical Co | 3,7-disubstituierte-3-cephem-4- carbonsaeure-verbindungen, verfahren zu ihrer herstellung und sie enthaltende pharmazeutische mittel |
DE2936434A1 (de) * | 1978-09-11 | 1980-03-20 | Fujisawa Pharmaceutical Co | Cephemverbindungen, verfahren zu ihrer herstellung, sie enthaltende pharmazeutische mittel sowie ihre therapeutische verwendung fuer die behandlung von infektionserkrankungen bei menschen und tieren |
EP0010667A1 (en) * | 1978-10-17 | 1980-05-14 | Fujisawa Pharmaceutical Co., Ltd. | Cepham compounds, pharmaceutical compositions containing them and processes for the preparation thereof and of known cephem compounds |
DE2945248A1 (de) * | 1978-11-13 | 1980-05-22 | Fujisawa Pharmaceutical Co | Cephem-verbindungen, verfahren zu ihrer herstellung und sie enthaltende antibakterielle pharmazeutische mittel |
DE3003724A1 (de) * | 1979-02-09 | 1980-08-21 | Roussel Uclaf | Neue oximderivate der 7-aminothiazolylacetamidocephalosporansaeure, ihre herstellung und verwendung |
DE3027281A1 (de) * | 1979-07-19 | 1981-02-12 | Roussel Uclaf | Alkyloximderivate der 7-(2-amino-4thiazolyl)-acetamido-cephalosporansaeure, ihre herstellung, neue zwischenprodukte sowie ihre anwendung als medikamente und in pharmazeutischen mitteln |
Also Published As
Publication number | Publication date |
---|---|
CH643557A5 (en) | 1984-06-15 |
CA1337522C (en) | 1995-11-07 |
SE457351B (sv) | 1988-12-19 |
IE45597L (en) | 1977-10-12 |
ES468719A1 (es) | 1979-10-16 |
DE2707565C2 (no) | 1988-06-30 |
NL191259C (nl) | 1995-04-18 |
DK75077A (da) | 1977-10-13 |
ATA138477A (de) | 1980-02-15 |
MX4985E (es) | 1983-01-31 |
ES477741A1 (es) | 1980-04-01 |
FR2348219A1 (fr) | 1977-11-10 |
CH638532A5 (de) | 1983-09-30 |
ES457191A1 (es) | 1978-08-16 |
ES485063A1 (es) | 1980-06-16 |
IE45597B1 (en) | 1982-10-06 |
FR2348219B1 (no) | 1982-12-03 |
SE7701964L (sv) | 1977-10-13 |
ES485062A1 (es) | 1980-06-16 |
DK162391B (da) | 1991-10-21 |
ES485064A1 (es) | 1980-10-01 |
AT358728B (de) | 1980-09-25 |
NL191259B (nl) | 1994-11-16 |
NL7703969A (nl) | 1977-10-14 |
SE8304465D0 (sv) | 1983-08-17 |
AR227864A1 (es) | 1982-12-30 |
SE443981B (sv) | 1986-03-17 |
AR223143A1 (es) | 1981-07-31 |
HU177441B (en) | 1981-10-28 |
ES485061A1 (es) | 1980-06-16 |
DK162391C (da) | 1992-03-09 |
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