DE2557033C2 - Acylderivate des 1,2-5,6-Dianhydro-dulcits, Verfahren zu deren Herstellung und diese Verbindungen enthaltende anticarcinogene Mittel - Google Patents

Acylderivate des 1,2-5,6-Dianhydro-dulcits, Verfahren zu deren Herstellung und diese Verbindungen enthaltende anticarcinogene Mittel

Info

Publication number
DE2557033C2
DE2557033C2 DE2557033A DE2557033A DE2557033C2 DE 2557033 C2 DE2557033 C2 DE 2557033C2 DE 2557033 A DE2557033 A DE 2557033A DE 2557033 A DE2557033 A DE 2557033A DE 2557033 C2 DE2557033 C2 DE 2557033C2
Authority
DE
Germany
Prior art keywords
dianhydro
dulcit
dad
diacetyl
tumor
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
DE2557033A
Other languages
German (de)
English (en)
Other versions
DE2557033A1 (de
Inventor
Agoston Dr. Budapest David
Sandor Dr. Eckhardt
Ilona Dr. Elekes
Laszlo Institoris
Zsuzsa Dr. Somfai
Janos Dr. Sugar
Anna Szabolcs
Sandor Dr. Virag
Laszlo Dr. Ötvös
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Chinoin Gyogyszer Es Vegyeszeti Termekek Gyara Rt 1045 Budapest Hu
Original Assignee
Chinoin Gyogyszer Es Vegyeszeti Termekek Gyara Rt 1045 Budapest Hu
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Chinoin Gyogyszer Es Vegyeszeti Termekek Gyara Rt 1045 Budapest Hu filed Critical Chinoin Gyogyszer Es Vegyeszeti Termekek Gyara Rt 1045 Budapest Hu
Publication of DE2557033A1 publication Critical patent/DE2557033A1/de
Application granted granted Critical
Publication of DE2557033C2 publication Critical patent/DE2557033C2/de
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D303/00—Compounds containing three-membered rings having one oxygen atom as the only ring hetero atom
    • C07D303/02—Compounds containing oxirane rings
    • C07D303/12—Compounds containing oxirane rings with hydrocarbon radicals, substituted by singly or doubly bound oxygen atoms
    • C07D303/16—Compounds containing oxirane rings with hydrocarbon radicals, substituted by singly or doubly bound oxygen atoms by esterified hydroxyl radicals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D303/00—Compounds containing three-membered rings having one oxygen atom as the only ring hetero atom
    • C07D303/02—Compounds containing oxirane rings
    • C07D303/12—Compounds containing oxirane rings with hydrocarbon radicals, substituted by singly or doubly bound oxygen atoms
    • C07D303/14—Compounds containing oxirane rings with hydrocarbon radicals, substituted by singly or doubly bound oxygen atoms by free hydroxyl radicals

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Epoxy Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
DE2557033A 1974-12-24 1975-12-18 Acylderivate des 1,2-5,6-Dianhydro-dulcits, Verfahren zu deren Herstellung und diese Verbindungen enthaltende anticarcinogene Mittel Expired DE2557033C2 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
HU74MA00002630A HU172826B (hu) 1974-12-24 1974-12-24 Sposob poluchenija novykh acilnykh proizvodnykh 1,2-5,6-diangidro-geksitov s protivoopukholevoj aktivnost'ju

Publications (2)

Publication Number Publication Date
DE2557033A1 DE2557033A1 (de) 1976-07-22
DE2557033C2 true DE2557033C2 (de) 1983-12-22

Family

ID=10998754

Family Applications (1)

Application Number Title Priority Date Filing Date
DE2557033A Expired DE2557033C2 (de) 1974-12-24 1975-12-18 Acylderivate des 1,2-5,6-Dianhydro-dulcits, Verfahren zu deren Herstellung und diese Verbindungen enthaltende anticarcinogene Mittel

Country Status (17)

Country Link
JP (1) JPS51125201A (it)
AT (1) AT345303B (it)
BE (1) BE837054A (it)
CH (1) CH620208A5 (it)
CS (1) CS220403B1 (it)
DD (1) DD124803A1 (it)
DE (1) DE2557033C2 (it)
DK (1) DK156271C (it)
FI (1) FI61187C (it)
FR (1) FR2295743A1 (it)
GB (1) GB1490649A (it)
HU (1) HU172826B (it)
NL (1) NL7514991A (it)
NO (1) NO144632C (it)
PL (1) PL101458B1 (it)
SU (1) SU581860A3 (it)
YU (1) YU40449B (it)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
HU182227B (en) * 1980-11-04 1983-12-28 Chinoin Gyogyszer Es Vegyeszet Process for preparing hexitols containing free carboxyl group
HU195754B (en) * 1984-01-18 1988-07-28 Chinoin Gyogyszer Es Vegyeszet Process for producing 1,2-5,6-dianhydro-3,4-diacyl-dulcitol
JPH0228032A (ja) * 1988-07-14 1990-01-30 Suzuki Motor Co Ltd 自動車
MX2013001858A (es) * 2010-08-18 2013-09-13 Del Mar Pharmaceuticals Composiciones y métodos para mejorar el beneficio terapéutico de los compuestos quimicos administrados de manera suboptima que incluyen hexitoles substituidos tal como dianhidrogalactitol y diacetildianhidrogalactitol.
US9901563B2 (en) 2013-03-11 2018-02-27 Delmar Pharmaceuticals, Inc. Compositions to improve the therapeutic benefit of suboptimally administered chemical compounds including substituted hexitols such as dianhydrogalactitol and diacetyldianhydrogalactitol

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
NICHTS-ERMITTELT

Also Published As

Publication number Publication date
JPS6129952B2 (it) 1986-07-10
DK589775A (da) 1976-06-25
HU172826B (hu) 1978-12-28
FR2295743B1 (it) 1978-11-10
YU40449B (en) 1986-02-28
DD124803A1 (it) 1977-03-16
DE2557033A1 (de) 1976-07-22
DK156271C (da) 1989-12-11
FR2295743A1 (fr) 1976-07-23
JPS51125201A (en) 1976-11-01
SU581860A3 (ru) 1977-11-25
DK156271B (da) 1989-07-24
GB1490649A (en) 1977-11-02
PL101458B1 (pl) 1978-12-30
FI61187B (fi) 1982-02-26
AT345303B (de) 1978-09-11
NO754374L (it) 1976-06-25
ATA966175A (de) 1978-01-15
NO144632C (no) 1981-10-07
CS220403B1 (en) 1983-04-29
FI753643A (it) 1976-06-25
BE837054A (fr) 1976-04-16
NO144632B (no) 1981-06-29
YU326975A (en) 1982-02-28
NL7514991A (nl) 1976-06-28
CH620208A5 (en) 1980-11-14
FI61187C (fi) 1982-06-10

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Legal Events

Date Code Title Description
8110 Request for examination paragraph 44
D2 Grant after examination
8364 No opposition during term of opposition
8328 Change in the person/name/address of the agent

Free format text: LOTTERHOS, H., DIPL.-ING. DR.-ING. BARTSCH, E., DIPL.-CHEM. DR.RER.NAT., PAT.-ANWAELTE, 6000 FRANKFURT