GB1490649A - Hexitol derivatives - Google Patents
Hexitol derivativesInfo
- Publication number
- GB1490649A GB1490649A GB52713/75A GB5271375A GB1490649A GB 1490649 A GB1490649 A GB 1490649A GB 52713/75 A GB52713/75 A GB 52713/75A GB 5271375 A GB5271375 A GB 5271375A GB 1490649 A GB1490649 A GB 1490649A
- Authority
- GB
- United Kingdom
- Prior art keywords
- hexitol derivatives
- compounds
- hexitol
- derivatives
- dianhydrohexitols
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D303/00—Compounds containing three-membered rings having one oxygen atom as the only ring hetero atom
- C07D303/02—Compounds containing oxirane rings
- C07D303/12—Compounds containing oxirane rings with hydrocarbon radicals, substituted by singly or doubly bound oxygen atoms
- C07D303/16—Compounds containing oxirane rings with hydrocarbon radicals, substituted by singly or doubly bound oxygen atoms by esterified hydroxyl radicals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D303/00—Compounds containing three-membered rings having one oxygen atom as the only ring hetero atom
- C07D303/02—Compounds containing oxirane rings
- C07D303/12—Compounds containing oxirane rings with hydrocarbon radicals, substituted by singly or doubly bound oxygen atoms
- C07D303/14—Compounds containing oxirane rings with hydrocarbon radicals, substituted by singly or doubly bound oxygen atoms by free hydroxyl radicals
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Epoxy Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Abstract
Compounds of the formula I in which the substituents Q1 and Q2 are the acyl radicals given in Claim 1 have anticarcinogenic properties. These compounds are prepared by acylating corresponding 1,2-5,6-dianhydrohexitols. <IMAGE>
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
HU74MA00002630A HU172826B (en) | 1974-12-24 | 1974-12-24 | Process for preparing new acyl derivatives of 1,2-5,6-dianhydro-hexites with tumor inhibiting activity |
Publications (1)
Publication Number | Publication Date |
---|---|
GB1490649A true GB1490649A (en) | 1977-11-02 |
Family
ID=10998754
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
GB52713/75A Expired GB1490649A (en) | 1974-12-24 | 1975-12-23 | Hexitol derivatives |
Country Status (17)
Country | Link |
---|---|
JP (1) | JPS51125201A (en) |
AT (1) | AT345303B (en) |
BE (1) | BE837054A (en) |
CH (1) | CH620208A5 (en) |
CS (1) | CS220403B1 (en) |
DD (1) | DD124803A1 (en) |
DE (1) | DE2557033C2 (en) |
DK (1) | DK156271C (en) |
FI (1) | FI61187C (en) |
FR (1) | FR2295743A1 (en) |
GB (1) | GB1490649A (en) |
HU (1) | HU172826B (en) |
NL (1) | NL7514991A (en) |
NO (1) | NO144632C (en) |
PL (1) | PL101458B1 (en) |
SU (1) | SU581860A3 (en) |
YU (1) | YU40449B (en) |
Cited By (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0051467A1 (en) * | 1980-11-04 | 1982-05-12 | CHINOIN Gyogyszer és Vegyészeti Termékek Gyára RT. | Hexitol derivatives, their preparation and pharmaceutical compositions containing them |
WO1985003293A1 (en) * | 1984-01-18 | 1985-08-01 | Chinoin Gyógyszer És Vegyészeti Termékek Gyára Rt | Process for producing diacyldiane hydrohexites |
EP3246026A3 (en) * | 2010-08-18 | 2018-02-21 | Del Mar Pharmaceuticals | Compositions and methods to improve the therapeutic benefit of suboptimally administered chemical compounds including substituted hexitols such as dianhydrogalactitol and diacetyldianhydrogalactitol |
US9901563B2 (en) | 2013-03-11 | 2018-02-27 | Delmar Pharmaceuticals, Inc. | Compositions to improve the therapeutic benefit of suboptimally administered chemical compounds including substituted hexitols such as dianhydrogalactitol and diacetyldianhydrogalactitol |
Families Citing this family (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPH0228032A (en) * | 1988-07-14 | 1990-01-30 | Suzuki Motor Co Ltd | Automobile |
-
1974
- 1974-12-24 HU HU74MA00002630A patent/HU172826B/en not_active IP Right Cessation
-
1975
- 1975-12-18 DE DE2557033A patent/DE2557033C2/en not_active Expired
- 1975-12-19 AT AT966175A patent/AT345303B/en not_active IP Right Cessation
- 1975-12-22 FR FR7539338A patent/FR2295743A1/en active Granted
- 1975-12-23 CS CS758837A patent/CS220403B1/en unknown
- 1975-12-23 PL PL1975185921A patent/PL101458B1/en unknown
- 1975-12-23 CH CH1673675A patent/CH620208A5/en not_active IP Right Cessation
- 1975-12-23 DK DK589775A patent/DK156271C/en not_active IP Right Cessation
- 1975-12-23 FI FI753643A patent/FI61187C/en not_active IP Right Cessation
- 1975-12-23 DD DD190504A patent/DD124803A1/xx not_active IP Right Cessation
- 1975-12-23 YU YU3269/75A patent/YU40449B/en unknown
- 1975-12-23 NL NL7514991A patent/NL7514991A/en not_active Application Discontinuation
- 1975-12-23 GB GB52713/75A patent/GB1490649A/en not_active Expired
- 1975-12-23 NO NO754374A patent/NO144632C/en unknown
- 1975-12-24 BE BE163090A patent/BE837054A/en not_active IP Right Cessation
- 1975-12-24 JP JP50154665A patent/JPS51125201A/en active Granted
- 1975-12-24 SU SU7502302301A patent/SU581860A3/en active
Cited By (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0051467A1 (en) * | 1980-11-04 | 1982-05-12 | CHINOIN Gyogyszer és Vegyészeti Termékek Gyára RT. | Hexitol derivatives, their preparation and pharmaceutical compositions containing them |
JPS57106642A (en) * | 1980-11-04 | 1982-07-02 | Chinoin Gyogyszer Es Vegyeszet | Hexitol, manufacture and medicinal composition containing same |
WO1985003293A1 (en) * | 1984-01-18 | 1985-08-01 | Chinoin Gyógyszer És Vegyészeti Termékek Gyára Rt | Process for producing diacyldiane hydrohexites |
GB2171992A (en) * | 1984-01-18 | 1986-09-10 | Chinoin Gyogyszer Es Vegyeszet | Process for producing diacyldiane hydrohexites |
US4820852A (en) * | 1984-01-18 | 1989-04-11 | Chinoin Gyogyszer Es Vegyeszeti Termekek Gyara | Process for the preparation of diacyl-dianhydro hexitols |
EP3246026A3 (en) * | 2010-08-18 | 2018-02-21 | Del Mar Pharmaceuticals | Compositions and methods to improve the therapeutic benefit of suboptimally administered chemical compounds including substituted hexitols such as dianhydrogalactitol and diacetyldianhydrogalactitol |
US9901563B2 (en) | 2013-03-11 | 2018-02-27 | Delmar Pharmaceuticals, Inc. | Compositions to improve the therapeutic benefit of suboptimally administered chemical compounds including substituted hexitols such as dianhydrogalactitol and diacetyldianhydrogalactitol |
Also Published As
Publication number | Publication date |
---|---|
ATA966175A (en) | 1978-01-15 |
CH620208A5 (en) | 1980-11-14 |
FI753643A (en) | 1976-06-25 |
JPS6129952B2 (en) | 1986-07-10 |
DE2557033C2 (en) | 1983-12-22 |
JPS51125201A (en) | 1976-11-01 |
SU581860A3 (en) | 1977-11-25 |
FR2295743A1 (en) | 1976-07-23 |
DE2557033A1 (en) | 1976-07-22 |
FI61187B (en) | 1982-02-26 |
NO144632C (en) | 1981-10-07 |
PL101458B1 (en) | 1978-12-30 |
AT345303B (en) | 1978-09-11 |
DK156271C (en) | 1989-12-11 |
HU172826B (en) | 1978-12-28 |
CS220403B1 (en) | 1983-04-29 |
NO754374L (en) | 1976-06-25 |
FI61187C (en) | 1982-06-10 |
YU326975A (en) | 1982-02-28 |
FR2295743B1 (en) | 1978-11-10 |
DK589775A (en) | 1976-06-25 |
BE837054A (en) | 1976-04-16 |
DK156271B (en) | 1989-07-24 |
NL7514991A (en) | 1976-06-28 |
NO144632B (en) | 1981-06-29 |
YU40449B (en) | 1986-02-28 |
DD124803A1 (en) | 1977-03-16 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
PS | Patent sealed [section 19, patents act 1949] | ||
746 | Register noted 'licences of right' (sect. 46/1977) | ||
PCNP | Patent ceased through non-payment of renewal fee |
Effective date: 19931223 |