GB1490649A - Hexitol derivatives - Google Patents

Hexitol derivatives

Info

Publication number
GB1490649A
GB1490649A GB52713/75A GB5271375A GB1490649A GB 1490649 A GB1490649 A GB 1490649A GB 52713/75 A GB52713/75 A GB 52713/75A GB 5271375 A GB5271375 A GB 5271375A GB 1490649 A GB1490649 A GB 1490649A
Authority
GB
United Kingdom
Prior art keywords
hexitol derivatives
compounds
hexitol
derivatives
dianhydrohexitols
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB52713/75A
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Chinoin Private Co Ltd
Original Assignee
Chinoin Gyogyszer es Vegyeszeti Termekek Gyara Zrt
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Chinoin Gyogyszer es Vegyeszeti Termekek Gyara Zrt filed Critical Chinoin Gyogyszer es Vegyeszeti Termekek Gyara Zrt
Publication of GB1490649A publication Critical patent/GB1490649A/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D303/00—Compounds containing three-membered rings having one oxygen atom as the only ring hetero atom
    • C07D303/02—Compounds containing oxirane rings
    • C07D303/12—Compounds containing oxirane rings with hydrocarbon radicals, substituted by singly or doubly bound oxygen atoms
    • C07D303/16—Compounds containing oxirane rings with hydrocarbon radicals, substituted by singly or doubly bound oxygen atoms by esterified hydroxyl radicals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D303/00—Compounds containing three-membered rings having one oxygen atom as the only ring hetero atom
    • C07D303/02—Compounds containing oxirane rings
    • C07D303/12—Compounds containing oxirane rings with hydrocarbon radicals, substituted by singly or doubly bound oxygen atoms
    • C07D303/14—Compounds containing oxirane rings with hydrocarbon radicals, substituted by singly or doubly bound oxygen atoms by free hydroxyl radicals

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Epoxy Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Abstract

Compounds of the formula I in which the substituents Q1 and Q2 are the acyl radicals given in Claim 1 have anticarcinogenic properties. These compounds are prepared by acylating corresponding 1,2-5,6-dianhydrohexitols. <IMAGE>
GB52713/75A 1974-12-24 1975-12-23 Hexitol derivatives Expired GB1490649A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
HU74MA00002630A HU172826B (en) 1974-12-24 1974-12-24 Process for preparing new acyl derivatives of 1,2-5,6-dianhydro-hexites with tumor inhibiting activity

Publications (1)

Publication Number Publication Date
GB1490649A true GB1490649A (en) 1977-11-02

Family

ID=10998754

Family Applications (1)

Application Number Title Priority Date Filing Date
GB52713/75A Expired GB1490649A (en) 1974-12-24 1975-12-23 Hexitol derivatives

Country Status (17)

Country Link
JP (1) JPS51125201A (en)
AT (1) AT345303B (en)
BE (1) BE837054A (en)
CH (1) CH620208A5 (en)
CS (1) CS220403B1 (en)
DD (1) DD124803A1 (en)
DE (1) DE2557033C2 (en)
DK (1) DK156271C (en)
FI (1) FI61187C (en)
FR (1) FR2295743A1 (en)
GB (1) GB1490649A (en)
HU (1) HU172826B (en)
NL (1) NL7514991A (en)
NO (1) NO144632C (en)
PL (1) PL101458B1 (en)
SU (1) SU581860A3 (en)
YU (1) YU40449B (en)

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0051467A1 (en) * 1980-11-04 1982-05-12 CHINOIN Gyogyszer és Vegyészeti Termékek Gyára RT. Hexitol derivatives, their preparation and pharmaceutical compositions containing them
WO1985003293A1 (en) * 1984-01-18 1985-08-01 Chinoin Gyógyszer És Vegyészeti Termékek Gyára Rt Process for producing diacyldiane hydrohexites
EP3246026A3 (en) * 2010-08-18 2018-02-21 Del Mar Pharmaceuticals Compositions and methods to improve the therapeutic benefit of suboptimally administered chemical compounds including substituted hexitols such as dianhydrogalactitol and diacetyldianhydrogalactitol
US9901563B2 (en) 2013-03-11 2018-02-27 Delmar Pharmaceuticals, Inc. Compositions to improve the therapeutic benefit of suboptimally administered chemical compounds including substituted hexitols such as dianhydrogalactitol and diacetyldianhydrogalactitol

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH0228032A (en) * 1988-07-14 1990-01-30 Suzuki Motor Co Ltd Automobile

Cited By (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0051467A1 (en) * 1980-11-04 1982-05-12 CHINOIN Gyogyszer és Vegyészeti Termékek Gyára RT. Hexitol derivatives, their preparation and pharmaceutical compositions containing them
JPS57106642A (en) * 1980-11-04 1982-07-02 Chinoin Gyogyszer Es Vegyeszet Hexitol, manufacture and medicinal composition containing same
WO1985003293A1 (en) * 1984-01-18 1985-08-01 Chinoin Gyógyszer És Vegyészeti Termékek Gyára Rt Process for producing diacyldiane hydrohexites
GB2171992A (en) * 1984-01-18 1986-09-10 Chinoin Gyogyszer Es Vegyeszet Process for producing diacyldiane hydrohexites
US4820852A (en) * 1984-01-18 1989-04-11 Chinoin Gyogyszer Es Vegyeszeti Termekek Gyara Process for the preparation of diacyl-dianhydro hexitols
EP3246026A3 (en) * 2010-08-18 2018-02-21 Del Mar Pharmaceuticals Compositions and methods to improve the therapeutic benefit of suboptimally administered chemical compounds including substituted hexitols such as dianhydrogalactitol and diacetyldianhydrogalactitol
US9901563B2 (en) 2013-03-11 2018-02-27 Delmar Pharmaceuticals, Inc. Compositions to improve the therapeutic benefit of suboptimally administered chemical compounds including substituted hexitols such as dianhydrogalactitol and diacetyldianhydrogalactitol

Also Published As

Publication number Publication date
ATA966175A (en) 1978-01-15
CH620208A5 (en) 1980-11-14
FI753643A (en) 1976-06-25
JPS6129952B2 (en) 1986-07-10
DE2557033C2 (en) 1983-12-22
JPS51125201A (en) 1976-11-01
SU581860A3 (en) 1977-11-25
FR2295743A1 (en) 1976-07-23
DE2557033A1 (en) 1976-07-22
FI61187B (en) 1982-02-26
NO144632C (en) 1981-10-07
PL101458B1 (en) 1978-12-30
AT345303B (en) 1978-09-11
DK156271C (en) 1989-12-11
HU172826B (en) 1978-12-28
CS220403B1 (en) 1983-04-29
NO754374L (en) 1976-06-25
FI61187C (en) 1982-06-10
YU326975A (en) 1982-02-28
FR2295743B1 (en) 1978-11-10
DK589775A (en) 1976-06-25
BE837054A (en) 1976-04-16
DK156271B (en) 1989-07-24
NL7514991A (en) 1976-06-28
NO144632B (en) 1981-06-29
YU40449B (en) 1986-02-28
DD124803A1 (en) 1977-03-16

Similar Documents

Publication Publication Date Title
SE390819B (en) ANALOGICAL PROCEDURE FOR THE PREPARATION OF PIPERAZINYL-PROPYL-1,2,4-TRIAZOLINE DERIVATIVES
NO143531C (en) PROCEDURE FOR THE PREPARATION OF ACYLATED BENZOCSAZOLINON DERIVATIVES.
GB1490649A (en) Hexitol derivatives
IT1031589B (en) PROCEDURE FOR THE PREPARATION OF 1.2.4 TRIAZOL DERIVATIVES
ES427893A1 (en) Combating weeds in rice with benzothiazole derivatives
CA975885A (en) Fluid rtv silicone compositions
SE7411990L (en)
GB1471847A (en) Dibenzofuran derivatives
ES428005A1 (en) 3,4-Dihydro-2H-naphthalene-1-one-5-oxypropyl-piperazine compounds
AR207242A1 (en) PROCEDURE FOR THE PREPARATION OF NEW DERIVATIVES OF PIRAZOLONES- (5) -1-SUBSTITUTED
SE428015B (en) PROCEDURE FOR THE PREPARATION OF 3.4-DIHYDROCARBOSTYRYL DERIVATIVE
NL7413166A (en) PROCESS FOR THE PREPARATION OF BIOLOGICALLY ACTIVE SITIONS.
SE431451B (en) PROCEDURE FOR THE PREPARATION OF 2,3-DIHYDROXIPROPOXICINOLINES OR ISOKINOLINES
SE7612961L (en) TIENAMYCIN DERIVATIVES
SE388611B (en) ANALOGICAL PROCEDURE FOR THE PREPARATION OF 1,4-BENZODIAZEPONE DERIVATIVES
IT974902B (en) PROCEDURE FOR THE MANUFACTURE OF 2 HYDROXYBEN ZOPHENONE DERIVATIVES
CA1028337A (en) Carbalkoxythioureidobenzene derivatives having anthelmintic properties
GB1080246A (en) 2-aryl-benzothiazole derivatives
SE8300870D0 (en) INTERMEDIATES FOR PREPARING DERIVATIVES OF 4 &#34;-DESOXY-4&#34; -AMINO-ERYTHROMYCINE A
SE7505272L (en) NEW, NITROGENIC, POLYCYCLIC ASSOCIATIONS JUST SEE FOR THEIR PREPARATION.
IT1030731B (en) JOINT FOR DOOR PARTICULARLY OF THE TYPE USED FOR ARNADES
SE7508857L (en) PROCEDURE FOR THE PREPARATION OF 19,20-BIS-NORPROSTANIC ACIDS.
ES423716A1 (en) 1-Oxo-hexahydroacridines
SE7512746L (en) METHOD OF MANUFACTURE NEW 7,7-DIPHENYL-HEXAHYDRO-1,4-OXAZEPINES
BE802006Q (en) STABILIZATION OF POLYMER COMPOSITIONS BY THE 3 &#39;

Legal Events

Date Code Title Description
PS Patent sealed [section 19, patents act 1949]
746 Register noted 'licences of right' (sect. 46/1977)
PCNP Patent ceased through non-payment of renewal fee

Effective date: 19931223