HU172826B - Process for preparing new acyl derivatives of 1,2-5,6-dianhydro-hexites with tumor inhibiting activity - Google Patents

Process for preparing new acyl derivatives of 1,2-5,6-dianhydro-hexites with tumor inhibiting activity

Info

Publication number
HU172826B
HU172826B HU74MA00002630A HUMA002630A HU172826B HU 172826 B HU172826 B HU 172826B HU 74MA00002630 A HU74MA00002630 A HU 74MA00002630A HU MA002630 A HUMA002630 A HU MA002630A HU 172826 B HU172826 B HU 172826B
Authority
HU
Hungary
Prior art keywords
hexites
dianhydro
inhibiting activity
acyl derivatives
preparing new
Prior art date
Application number
HU74MA00002630A
Other languages
Hungarian (hu)
Inventor
Laszlo Oetvoes
Sandor Eckhardt
Anna Szabolcs
Ilona Elekes
Zsuzsa Somfai
Janos Sugar
Laszlo Institoris
Sandor Virag
Agoston David
Original Assignee
Mta Koezponti Kemiai Kutato In
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Mta Koezponti Kemiai Kutato In filed Critical Mta Koezponti Kemiai Kutato In
Priority to HU74MA00002630A priority Critical patent/HU172826B/en
Priority to DE2557033A priority patent/DE2557033C2/en
Priority to AT966175A priority patent/AT345303B/en
Priority to FR7539338A priority patent/FR2295743A1/en
Priority to CS758837A priority patent/CS220403B1/en
Priority to PL1975185921A priority patent/PL101458B1/en
Priority to DK589775A priority patent/DK156271C/en
Priority to NL7514991A priority patent/NL7514991A/en
Priority to YU3269/75A priority patent/YU40449B/en
Priority to CH1673675A priority patent/CH620208A5/en
Priority to NO754374A priority patent/NO144632C/en
Priority to GB52713/75A priority patent/GB1490649A/en
Priority to FI753643A priority patent/FI61187C/en
Priority to DD190504A priority patent/DD124803A1/xx
Priority to BE163090A priority patent/BE837054A/en
Priority to JP50154665A priority patent/JPS51125201A/en
Priority to SU7502302301A priority patent/SU581860A3/en
Publication of HU172826B publication Critical patent/HU172826B/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D303/00—Compounds containing three-membered rings having one oxygen atom as the only ring hetero atom
    • C07D303/02—Compounds containing oxirane rings
    • C07D303/12—Compounds containing oxirane rings with hydrocarbon radicals, substituted by singly or doubly bound oxygen atoms
    • C07D303/16—Compounds containing oxirane rings with hydrocarbon radicals, substituted by singly or doubly bound oxygen atoms by esterified hydroxyl radicals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D303/00—Compounds containing three-membered rings having one oxygen atom as the only ring hetero atom
    • C07D303/02—Compounds containing oxirane rings
    • C07D303/12—Compounds containing oxirane rings with hydrocarbon radicals, substituted by singly or doubly bound oxygen atoms
    • C07D303/14—Compounds containing oxirane rings with hydrocarbon radicals, substituted by singly or doubly bound oxygen atoms by free hydroxyl radicals

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Epoxy Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
HU74MA00002630A 1974-12-24 1974-12-24 Process for preparing new acyl derivatives of 1,2-5,6-dianhydro-hexites with tumor inhibiting activity HU172826B (en)

Priority Applications (17)

Application Number Priority Date Filing Date Title
HU74MA00002630A HU172826B (en) 1974-12-24 1974-12-24 Process for preparing new acyl derivatives of 1,2-5,6-dianhydro-hexites with tumor inhibiting activity
DE2557033A DE2557033C2 (en) 1974-12-24 1975-12-18 Acyl derivatives of 1,2-5,6-dianhydro-dulcite, processes for their preparation and anticarcinogenic agents containing these compounds
AT966175A AT345303B (en) 1974-12-24 1975-12-19 PROCESS FOR THE PRODUCTION OF NEW CARINOSTATIC DIANHYDRO-HEXITE DERIVATIVES
FR7539338A FR2295743A1 (en) 1974-12-24 1975-12-22 ACYL DERIVATIVES OF DIANHYDRO-HEXITOLS HAVING ANTITUMOR ACTIVITY AND PROCESS FOR THEIR PREPARATION
CS758837A CS220403B1 (en) 1974-12-24 1975-12-23 Acyl derivatives of dianhydrohexitol and method of preparing same
PL1975185921A PL101458B1 (en) 1974-12-24 1975-12-23 METHOD OF MAKING NEW DERIVATIVES OF DIANHYDROHEXITOL
DK589775A DK156271C (en) 1974-12-24 1975-12-23 METHOD OF ANALOGUE FOR THE PREPARATION OF 1,2-5,6-DIANHYDRO-3,4-DI-O-ACYLGALACTITOLD DERIVATIVES
NL7514991A NL7514991A (en) 1974-12-24 1975-12-23 PROCESS FOR THE PREPARATION OF ACYL DERIVATIVES OF DIANHYDRO HEXITOLS.
YU3269/75A YU40449B (en) 1974-12-24 1975-12-23 Process for obtaining new dianhydrodulcite derivatives
CH1673675A CH620208A5 (en) 1974-12-24 1975-12-23 Process for the preparation of anticarcinogenic dianhydrohexitide-acyl derivatives
NO754374A NO144632C (en) 1974-12-24 1975-12-23 ANALOGUE PROCEDURE FOR THE PREPARATION OF NEW THERAPEUTICALLY ACTIVE DIANHYDROHEXITID ACYL DERIVATIVES
GB52713/75A GB1490649A (en) 1974-12-24 1975-12-23 Hexitol derivatives
FI753643A FI61187C (en) 1974-12-24 1975-12-23 FREQUENCY REFRIGERATION OF ANTITUMO 1,2,5,6-DIANHYDRO-3,4-DI-0-ACYLGALACTTOLDERIVAT
DD190504A DD124803A1 (en) 1974-12-24 1975-12-23
BE163090A BE837054A (en) 1974-12-24 1975-12-24 ACYL DERIVATIVES OF DIANHYDRO-HEXITOLS HAVING ANTITUMOR ACTIVITY AND PROCESS FOR THEIR PREPARATION
JP50154665A JPS51125201A (en) 1974-12-24 1975-12-24 Antitumor compound
SU7502302301A SU581860A3 (en) 1974-12-24 1975-12-24 Method of preparing acyl derivatives of dianhydrohexitols

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
HU74MA00002630A HU172826B (en) 1974-12-24 1974-12-24 Process for preparing new acyl derivatives of 1,2-5,6-dianhydro-hexites with tumor inhibiting activity

Publications (1)

Publication Number Publication Date
HU172826B true HU172826B (en) 1978-12-28

Family

ID=10998754

Family Applications (1)

Application Number Title Priority Date Filing Date
HU74MA00002630A HU172826B (en) 1974-12-24 1974-12-24 Process for preparing new acyl derivatives of 1,2-5,6-dianhydro-hexites with tumor inhibiting activity

Country Status (17)

Country Link
JP (1) JPS51125201A (en)
AT (1) AT345303B (en)
BE (1) BE837054A (en)
CH (1) CH620208A5 (en)
CS (1) CS220403B1 (en)
DD (1) DD124803A1 (en)
DE (1) DE2557033C2 (en)
DK (1) DK156271C (en)
FI (1) FI61187C (en)
FR (1) FR2295743A1 (en)
GB (1) GB1490649A (en)
HU (1) HU172826B (en)
NL (1) NL7514991A (en)
NO (1) NO144632C (en)
PL (1) PL101458B1 (en)
SU (1) SU581860A3 (en)
YU (1) YU40449B (en)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
HU182227B (en) * 1980-11-04 1983-12-28 Chinoin Gyogyszer Es Vegyeszet Process for preparing hexitols containing free carboxyl group
HU195754B (en) * 1984-01-18 1988-07-28 Chinoin Gyogyszer Es Vegyeszet Process for producing 1,2-5,6-dianhydro-3,4-diacyl-dulcitol
JPH0228032A (en) * 1988-07-14 1990-01-30 Suzuki Motor Co Ltd Automobile
US9901563B2 (en) 2013-03-11 2018-02-27 Delmar Pharmaceuticals, Inc. Compositions to improve the therapeutic benefit of suboptimally administered chemical compounds including substituted hexitols such as dianhydrogalactitol and diacetyldianhydrogalactitol
JP2013537552A (en) * 2010-08-18 2013-10-03 デル マー ファーマスーティカルズ Compositions and methods for improving the therapeutic efficacy of suboptimally administered compounds containing substituted hexitols such as dianhydrogalactitol and diacetyldianhydrogalactitol

Also Published As

Publication number Publication date
DK156271B (en) 1989-07-24
NL7514991A (en) 1976-06-28
CH620208A5 (en) 1980-11-14
ATA966175A (en) 1978-01-15
NO754374L (en) 1976-06-25
DE2557033A1 (en) 1976-07-22
NO144632C (en) 1981-10-07
FI753643A (en) 1976-06-25
DK156271C (en) 1989-12-11
YU326975A (en) 1982-02-28
FI61187C (en) 1982-06-10
FR2295743B1 (en) 1978-11-10
AT345303B (en) 1978-09-11
DK589775A (en) 1976-06-25
PL101458B1 (en) 1978-12-30
GB1490649A (en) 1977-11-02
DE2557033C2 (en) 1983-12-22
FR2295743A1 (en) 1976-07-23
BE837054A (en) 1976-04-16
CS220403B1 (en) 1983-04-29
DD124803A1 (en) 1977-03-16
YU40449B (en) 1986-02-28
JPS6129952B2 (en) 1986-07-10
FI61187B (en) 1982-02-26
NO144632B (en) 1981-06-29
JPS51125201A (en) 1976-11-01
SU581860A3 (en) 1977-11-25

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Legal Events

Date Code Title Description
HU90 Patent valid on 900628
HMM4 Cancellation of final prot. due to non-payment of fee