FR2295743A1 - Derives acyles de dianhydro-hexitols ayant une activite antitumorale et procede pour leur preparation - Google Patents

Derives acyles de dianhydro-hexitols ayant une activite antitumorale et procede pour leur preparation

Info

Publication number
FR2295743A1
FR2295743A1 FR7539338A FR7539338A FR2295743A1 FR 2295743 A1 FR2295743 A1 FR 2295743A1 FR 7539338 A FR7539338 A FR 7539338A FR 7539338 A FR7539338 A FR 7539338A FR 2295743 A1 FR2295743 A1 FR 2295743A1
Authority
FR
France
Prior art keywords
dianhydro
hexitols
preparation
antitumor activity
acyl derivatives
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
FR7539338A
Other languages
English (en)
French (fr)
Other versions
FR2295743B1 (it
Inventor
Laszlo Otvos
Sandor Eckhardt
Anna Szabolcs
Ilona Elekes
Zsuzsa Somfai
Janos Sugar
Laszlo Institoris
Sandor Virag
Agoston David
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Chinoin Private Co Ltd
Original Assignee
Chinoin Gyogyszer es Vegyeszeti Termekek Gyara Zrt
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Chinoin Gyogyszer es Vegyeszeti Termekek Gyara Zrt filed Critical Chinoin Gyogyszer es Vegyeszeti Termekek Gyara Zrt
Publication of FR2295743A1 publication Critical patent/FR2295743A1/fr
Application granted granted Critical
Publication of FR2295743B1 publication Critical patent/FR2295743B1/fr
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D303/00—Compounds containing three-membered rings having one oxygen atom as the only ring hetero atom
    • C07D303/02—Compounds containing oxirane rings
    • C07D303/12—Compounds containing oxirane rings with hydrocarbon radicals, substituted by singly or doubly bound oxygen atoms
    • C07D303/16—Compounds containing oxirane rings with hydrocarbon radicals, substituted by singly or doubly bound oxygen atoms by esterified hydroxyl radicals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D303/00—Compounds containing three-membered rings having one oxygen atom as the only ring hetero atom
    • C07D303/02—Compounds containing oxirane rings
    • C07D303/12—Compounds containing oxirane rings with hydrocarbon radicals, substituted by singly or doubly bound oxygen atoms
    • C07D303/14—Compounds containing oxirane rings with hydrocarbon radicals, substituted by singly or doubly bound oxygen atoms by free hydroxyl radicals

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Epoxy Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
FR7539338A 1974-12-24 1975-12-22 Derives acyles de dianhydro-hexitols ayant une activite antitumorale et procede pour leur preparation Granted FR2295743A1 (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
HU74MA00002630A HU172826B (hu) 1974-12-24 1974-12-24 Sposob poluchenija novykh acilnykh proizvodnykh 1,2-5,6-diangidro-geksitov s protivoopukholevoj aktivnost'ju

Publications (2)

Publication Number Publication Date
FR2295743A1 true FR2295743A1 (fr) 1976-07-23
FR2295743B1 FR2295743B1 (it) 1978-11-10

Family

ID=10998754

Family Applications (1)

Application Number Title Priority Date Filing Date
FR7539338A Granted FR2295743A1 (fr) 1974-12-24 1975-12-22 Derives acyles de dianhydro-hexitols ayant une activite antitumorale et procede pour leur preparation

Country Status (17)

Country Link
JP (1) JPS51125201A (it)
AT (1) AT345303B (it)
BE (1) BE837054A (it)
CH (1) CH620208A5 (it)
CS (1) CS220403B1 (it)
DD (1) DD124803A1 (it)
DE (1) DE2557033C2 (it)
DK (1) DK156271C (it)
FI (1) FI61187C (it)
FR (1) FR2295743A1 (it)
GB (1) GB1490649A (it)
HU (1) HU172826B (it)
NL (1) NL7514991A (it)
NO (1) NO144632C (it)
PL (1) PL101458B1 (it)
SU (1) SU581860A3 (it)
YU (1) YU40449B (it)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
HU182227B (en) * 1980-11-04 1983-12-28 Chinoin Gyogyszer Es Vegyeszet Process for preparing hexitols containing free carboxyl group
HU195754B (en) * 1984-01-18 1988-07-28 Chinoin Gyogyszer Es Vegyeszet Process for producing 1,2-5,6-dianhydro-3,4-diacyl-dulcitol
JPH0228032A (ja) * 1988-07-14 1990-01-30 Suzuki Motor Co Ltd 自動車
MX2013001858A (es) * 2010-08-18 2013-09-13 Del Mar Pharmaceuticals Composiciones y métodos para mejorar el beneficio terapéutico de los compuestos quimicos administrados de manera suboptima que incluyen hexitoles substituidos tal como dianhidrogalactitol y diacetildianhidrogalactitol.
US9901563B2 (en) 2013-03-11 2018-02-27 Delmar Pharmaceuticals, Inc. Compositions to improve the therapeutic benefit of suboptimally administered chemical compounds including substituted hexitols such as dianhydrogalactitol and diacetyldianhydrogalactitol

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
TETRAHEDRON LETTERS", 1975, PAGES 2477-2480) *

Also Published As

Publication number Publication date
JPS6129952B2 (it) 1986-07-10
DK589775A (da) 1976-06-25
HU172826B (hu) 1978-12-28
FR2295743B1 (it) 1978-11-10
YU40449B (en) 1986-02-28
DD124803A1 (it) 1977-03-16
DE2557033A1 (de) 1976-07-22
DK156271C (da) 1989-12-11
JPS51125201A (en) 1976-11-01
SU581860A3 (ru) 1977-11-25
DK156271B (da) 1989-07-24
GB1490649A (en) 1977-11-02
PL101458B1 (pl) 1978-12-30
FI61187B (fi) 1982-02-26
AT345303B (de) 1978-09-11
NO754374L (it) 1976-06-25
ATA966175A (de) 1978-01-15
NO144632C (no) 1981-10-07
CS220403B1 (en) 1983-04-29
FI753643A (it) 1976-06-25
BE837054A (fr) 1976-04-16
DE2557033C2 (de) 1983-12-22
NO144632B (no) 1981-06-29
YU326975A (en) 1982-02-28
NL7514991A (nl) 1976-06-28
CH620208A5 (en) 1980-11-14
FI61187C (fi) 1982-06-10

Similar Documents

Publication Publication Date Title
BE823411A (fr) Nouveaux derives de la phenoxypropylamine et procede pour leur preparation
BE823400A (fr) Derives de 2-acyl-4-oxo-pyrazino-isoquinoleine et leur procede de preparation
BE824697A (fr) Derives de benzylamine et leur procede de preparation
BE746034A (fr) Nouveaux derives de la phenothiazine et procede pour leur preparation
BE823027A (fr) Derives d'isoquinoleine et leur procede de preparation
BE827582A (fr) Nouveaux derives de 2-arylamino-2-imidazoline et procede pour leur preparation
FR2296631A1 (fr) Derives de cyclopentane et leur procede de preparation
BE838079A (fr) Derives de tetrahydroisoquinoleine et leur procede de preparation
BE818048A (fr) Tetrahydroacridones ayant une activite chimiotherapeutique et leur procede de preparation
FR2295743A1 (fr) Derives acyles de dianhydro-hexitols ayant une activite antitumorale et procede pour leur preparation
FR2279410A1 (fr) Derives acyles de pyrazofurine et leur procede de preparation
BE840871A (fr) Derives de ll-oxo-prostaglandine et leur procede de preparation
FR2290207A1 (fr) Nouveaux derives de 3,4-dihydrocarbostyril et leur procede de preparation
BE814661A (fr) Derives benzimidazoliques et procede pour leur preparation
BE823873A (fr) Derives de benzopyranne et leur procede de preparation
FR2281102A1 (fr) Nouveaux derives de nitrosouree et procede pour leur preparation
BE769766A (fr) Nouveaux derives de spiramycine et leur procede de preparation
BE822766A (fr) Nouveaux derives d'amides alpha-aminoxycarboxyliques substitueset leur procede de preparation
FR2309229A1 (fr) Nouveaux derives de triazolobenzocycloalkylthiadiazine et leur procede de preparation
BE844520R (fr) Nouveaux derives de la phenothiazine et procede pour leur preparation
BE819591A (fr) Derives cephem et leur procede de preparation
BE826062A (fr) Derives de phenylbutanol et leur procede de preparation
FR2319608A1 (fr) Nouveaux derives de n-(a-cyanoalkyl)- diaminomaleonitriles et leur procede de preparation
FR2331334A1 (fr) Derives d-substitues de la negamycine et procede pour leur synthese
BE830582A (fr) Nouveaux derives de la benzodiazepine et leur procede de preparation

Legal Events

Date Code Title Description
ST Notification of lapse