BE823411A - Nouveaux derives de la phenoxypropylamine et procede pour leur preparation - Google Patents

Nouveaux derives de la phenoxypropylamine et procede pour leur preparation

Info

Publication number
BE823411A
BE823411A BE151557A BE151557A BE823411A BE 823411 A BE823411 A BE 823411A BE 151557 A BE151557 A BE 151557A BE 151557 A BE151557 A BE 151557A BE 823411 A BE823411 A BE 823411A
Authority
BE
Belgium
Prior art keywords
phenoxypropylamine
preparation
new derivatives
derivatives
new
Prior art date
Application number
BE151557A
Other languages
English (en)
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed filed Critical
Publication of BE823411A publication Critical patent/BE823411A/fr

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D303/00—Compounds containing three-membered rings having one oxygen atom as the only ring hetero atom
    • C07D303/02—Compounds containing oxirane rings
    • C07D303/12—Compounds containing oxirane rings with hydrocarbon radicals, substituted by singly or doubly bound oxygen atoms
    • C07D303/18—Compounds containing oxirane rings with hydrocarbon radicals, substituted by singly or doubly bound oxygen atoms by etherified hydroxyl radicals
    • C07D303/20—Ethers with hydroxy compounds containing no oxirane rings
    • C07D303/22—Ethers with hydroxy compounds containing no oxirane rings with monohydroxy compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C275/00—Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups
    • C07C275/28—Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of urea groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton
    • C07C275/38—Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of urea groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton being further substituted by doubly-bound oxygen atoms

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Cardiology (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
BE151557A 1973-12-20 1974-12-16 Nouveaux derives de la phenoxypropylamine et procede pour leur preparation BE823411A (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
AT1066673A AT334385B (de) 1973-12-20 1973-12-20 Verfahren zur herstellung von neuen phenoxypropylaminderivaten und deren salzen

Publications (1)

Publication Number Publication Date
BE823411A true BE823411A (fr) 1975-06-16

Family

ID=3623884

Family Applications (1)

Application Number Title Priority Date Filing Date
BE151557A BE823411A (fr) 1973-12-20 1974-12-16 Nouveaux derives de la phenoxypropylamine et procede pour leur preparation

Country Status (19)

Country Link
US (1) US4034009A (fr)
JP (2) JPS5412461B2 (fr)
AT (1) AT334385B (fr)
BE (1) BE823411A (fr)
CA (1) CA1001626A (fr)
CH (1) CH612417A5 (fr)
CS (1) CS185669B2 (fr)
DD (1) DD118421A1 (fr)
ES (1) ES433145A1 (fr)
FR (1) FR2255058B1 (fr)
GB (1) GB1441359A (fr)
IE (1) IE40310B1 (fr)
IL (1) IL46259A (fr)
LU (2) LU71514A1 (fr)
PL (1) PL94095B1 (fr)
RO (1) RO69147A (fr)
SU (1) SU547174A3 (fr)
YU (1) YU36492B (fr)
ZA (1) ZA748067B (fr)

Families Citing this family (30)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4177280A (en) * 1978-07-03 1979-12-04 Syntex (U.S.A.) Inc. Bicyclo[3.1.0]hexyl-substituted carbonylaminophenoxy cardiovascular agents
JPS5757231U (fr) * 1980-09-19 1982-04-03
US4470965A (en) * 1982-10-27 1984-09-11 Usv Pharmaceutical Corporation Celiprolol for the treatment of glaucoma
JPS60164639A (ja) * 1984-02-07 1985-08-27 Hitachi Ltd 燃料噴射弁の駆動制御装置
DE3410380A1 (de) * 1984-03-21 1985-10-10 Lentia GmbH Chem. u. pharm. Erzeugnisse - Industriebedarf, 8000 München S(-)-celiprolol, dessen pharmazeutisch vertraegliche salze, verfahren zu dessen herstellung, verwendung in der therapie und pharmazeutische zubereitungen
DE3544172A1 (de) * 1985-12-13 1987-06-19 Lentia Gmbh Neue kristalline salze von aryloxy-propanolaminen, verfahren zu ihrer herstellung und ihre verwendung
DE3636209A1 (de) * 1986-10-24 1988-04-28 Lentia Gmbh Verfahren zur herstellung eines bindemittelfreien tablettierfaehigen celiprololhydrochlorid-granulates
CN1681495B (zh) 2002-08-19 2010-05-12 辉瑞产品公司 用于治疗过度增生性疾病的组合物
WO2004106299A2 (fr) * 2003-05-30 2004-12-09 Ranbaxy Laboratories Limited Derives pyrroliques substitues
GT200600381A (es) 2005-08-25 2007-03-28 Compuestos organicos
WO2007029155A2 (fr) * 2005-09-05 2007-03-15 Ranbaxy Laboratories Limited Procede de preparation ameliore d'une base de celiprolol pure
US7741317B2 (en) 2005-10-21 2010-06-22 Bristol-Myers Squibb Company LXR modulators
KR101329112B1 (ko) * 2005-11-08 2013-11-14 랜박시 래보러터리스 리미티드 (3ｒ,5ｒ)-7-〔2-(4-플루오로페닐)-5-이소프로필-3-페닐-4-〔(4-히드록시 메틸 페닐 아미노)카르보닐〕-피롤-1-일〕-3,5-디히드록시 헵탄산 헤미 칼슘염의 제조 방법
US7888376B2 (en) 2005-11-23 2011-02-15 Bristol-Myers Squibb Company Heterocyclic CETP inhibitors
WO2008020314A2 (fr) * 2006-03-14 2008-02-21 Ranbaxy Laboratories Limited Formulations de dosage stabilisantes à base de statine
MX2009000439A (es) * 2006-07-14 2009-02-04 Ranbaxy Lab Ltd Formas polimorficas de un inhibidor de hmg-coa reductasa y usos de las mismas.
CN101663262B (zh) 2006-12-01 2014-03-26 百时美施贵宝公司 用于治疗动脉粥样硬化和心血管疾病的作为cetp抑制剂的n-(3-苄基)-2,2-(二苯基)-丙-1胺衍生物
ES2393885T7 (es) 2007-06-04 2014-01-30 Synergy Pharmaceuticals Inc. Agonistas de la guanilato ciclasa útiles para el tratamiento de trastornos gastrointestinales, inflamación, cáncer y otros trastornos
US8969514B2 (en) 2007-06-04 2015-03-03 Synergy Pharmaceuticals, Inc. Agonists of guanylate cyclase useful for the treatment of hypercholesterolemia, atherosclerosis, coronary heart disease, gallstone, obesity and other cardiovascular diseases
EP2050441A1 (fr) * 2007-10-19 2009-04-22 Université Victor Segalen Bordeaux 2 Utilisation de bêtabloquants pour la fabrication d'un médicament pour le traitement d'hémangiomes
US8987262B2 (en) 2007-10-19 2015-03-24 Universite de Bordeaux Use of a beta blocker for the manufacture of a medicament for the treatment of hemangiomas
ES2522968T3 (es) 2008-06-04 2014-11-19 Synergy Pharmaceuticals Inc. Agonistas de guanilato ciclasa útiles para el tratamiento de trastornos gastrointestinales, inflamación, cáncer y otros trastornos
AU2009270833B2 (en) 2008-07-16 2015-02-19 Bausch Health Ireland Limited Agonists of guanylate cyclase useful for the treatment of gastrointestinal, inflammation, cancer and other disorders
US9616097B2 (en) 2010-09-15 2017-04-11 Synergy Pharmaceuticals, Inc. Formulations of guanylate cyclase C agonists and methods of use
CA2905435A1 (fr) 2013-03-15 2014-09-25 Synergy Pharmaceuticals Inc. Compositions utiles pour le traitement de troubles gastro-intestinaux
JP2016514671A (ja) 2013-03-15 2016-05-23 シナジー ファーマシューティカルズ インコーポレイテッド グアニル酸シクラーゼのアゴニストおよびその使用
WO2014170786A1 (fr) 2013-04-17 2014-10-23 Pfizer Inc. Dérivés de n-pipéridin-3-ylbenzamide dans le traitement des maladies cardiovasculaires
US10011637B2 (en) 2013-06-05 2018-07-03 Synergy Pharmaceuticals, Inc. Ultra-pure agonists of guanylate cyclase C, method of making and using same
WO2016055901A1 (fr) 2014-10-08 2016-04-14 Pfizer Inc. Composés d'amide substitué
CN113574055A (zh) 2019-01-18 2021-10-29 阿斯利康(瑞典)有限公司 Pcsk9抑制剂及其使用方法

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1214012A (en) * 1967-12-21 1970-11-25 Allen & Hanburys Ltd Phenylethanolamines
AT292671B (de) * 1967-12-22 1971-09-10 May & Baker Ltd Verfahren zur Herstellung von neuen 3-(4'-Alkanoylamino-2'-acylphenoxy)-2-hydroxy-1-aminopropanen
US3935259A (en) * 1970-01-08 1976-01-27 Ciba-Geigy Corporation New amines and processes for their manufacture
SE354851B (fr) * 1970-02-18 1973-03-26 Haessle Ab
NL7115581A (fr) * 1970-11-13 1972-05-16 Dresden Arzneimittel
GB1396322A (en) * 1971-06-15 1975-06-04 Ici Ltd Alkanolamine derivatives
SE386892B (sv) * 1972-07-06 1976-08-23 Haessle Ab Forfarande for framstellning av oxaminoforeningar
GB1455116A (en) * 1972-12-15 1976-11-10 Ici Ltd Pharmaceutical compositions
AT330150B (de) * 1973-02-28 1976-06-10 Boehringer Sohn Ingelheim Verfahren zur herstellung von neuen 1-phenoxy-2-hydroxy -3- propargylaminopropanen und von deren saureadditionssalzen
GB1460593A (en) * 1973-06-22 1977-01-06 Ici Ltd Ethanolamine derivatives
FI65987C (fi) * 1973-12-12 1984-08-10 Ici Ltd Foerfarande foer framstaellning av nya terapeutiskt anvaendbara alkanolaminderivat
AT334386B (de) * 1973-12-21 1976-01-10 Chemie Linz Ag Verfahren zur herstellung von neuen phenoxypropylaminderivaten und deren salzen

Also Published As

Publication number Publication date
SU547174A3 (ru) 1977-02-15
ES433145A1 (es) 1976-11-16
YU327774A (en) 1982-02-25
FR2255058A1 (fr) 1975-07-18
JPS5412461B2 (fr) 1979-05-23
RO69147A (fr) 1981-07-30
US4034009A (en) 1977-07-05
JPS5095246A (fr) 1975-07-29
CS185669B2 (en) 1978-10-31
JPS53149947A (en) 1978-12-27
LU88296I2 (fr) 1994-05-04
ATA1066673A (de) 1976-05-15
LU71514A1 (fr) 1975-08-20
FR2255058B1 (fr) 1978-07-28
GB1441359A (en) 1976-06-30
CA1001626A (en) 1976-12-14
AT334385B (de) 1976-01-10
ZA748067B (en) 1976-01-28
AU7653874A (en) 1976-06-17
IE40310B1 (en) 1979-04-25
YU36492B (en) 1984-02-29
PL94095B1 (fr) 1977-07-30
CH612417A5 (fr) 1979-07-31
IE40310L (en) 1975-06-20
IL46259A0 (en) 1975-03-13
JPS5549071B2 (fr) 1980-12-10
DD118421A1 (fr) 1976-03-05
IL46259A (en) 1978-04-30

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Legal Events

Date Code Title Description
CCPA Application for a supplementary protection certificate

Free format text: 093C0095

CN Change of patent owner's name
RE20 Patent expired

Owner name: RHONE-POULENC RORER INTERNATIONAL (HOLDINGS) INC.

Effective date: 19941216

CCPV Grant of a supplementary protection certificate

Free format text: 093C0095, EXPIRES 19991216