JPS53149947A - New derivative of phenoxypropylamine and method for production of its salt - Google Patents

New derivative of phenoxypropylamine and method for production of its salt

Info

Publication number
JPS53149947A
JPS53149947A JP3982678A JP3982678A JPS53149947A JP S53149947 A JPS53149947 A JP S53149947A JP 3982678 A JP3982678 A JP 3982678A JP 3982678 A JP3982678 A JP 3982678A JP S53149947 A JPS53149947 A JP S53149947A
Authority
JP
Japan
Prior art keywords
phenoxypropylamine
salt
production
new derivative
derivative
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP3982678A
Other languages
English (en)
Other versions
JPS5549071B2 (ja
Inventor
Tsueerusu Geruharuto
Pitsutoneru Heriberuto
Shiyutooruman Meningeru Haimo
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Patheon Austria GmbH and Co KG
Original Assignee
Chemie Linz AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Chemie Linz AG filed Critical Chemie Linz AG
Publication of JPS53149947A publication Critical patent/JPS53149947A/ja
Publication of JPS5549071B2 publication Critical patent/JPS5549071B2/ja
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D303/00—Compounds containing three-membered rings having one oxygen atom as the only ring hetero atom
    • C07D303/02—Compounds containing oxirane rings
    • C07D303/12—Compounds containing oxirane rings with hydrocarbon radicals, substituted by singly or doubly bound oxygen atoms
    • C07D303/18—Compounds containing oxirane rings with hydrocarbon radicals, substituted by singly or doubly bound oxygen atoms by etherified hydroxyl radicals
    • C07D303/20—Ethers with hydroxy compounds containing no oxirane rings
    • C07D303/22—Ethers with hydroxy compounds containing no oxirane rings with monohydroxy compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C275/00—Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups
    • C07C275/28—Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of urea groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton
    • C07C275/38—Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of urea groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton being further substituted by doubly-bound oxygen atoms

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Cardiology (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
JP3982678A 1973-12-20 1978-04-06 New derivative of phenoxypropylamine and method for production of its salt Granted JPS53149947A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
AT1066673A AT334385B (de) 1973-12-20 1973-12-20 Verfahren zur herstellung von neuen phenoxypropylaminderivaten und deren salzen

Publications (2)

Publication Number Publication Date
JPS53149947A true JPS53149947A (en) 1978-12-27
JPS5549071B2 JPS5549071B2 (ja) 1980-12-10

Family

ID=3623884

Family Applications (2)

Application Number Title Priority Date Filing Date
JP14586074A Expired JPS5412461B2 (ja) 1973-12-20 1974-12-20
JP3982678A Granted JPS53149947A (en) 1973-12-20 1978-04-06 New derivative of phenoxypropylamine and method for production of its salt

Family Applications Before (1)

Application Number Title Priority Date Filing Date
JP14586074A Expired JPS5412461B2 (ja) 1973-12-20 1974-12-20

Country Status (19)

Country Link
US (1) US4034009A (ja)
JP (2) JPS5412461B2 (ja)
AT (1) AT334385B (ja)
BE (1) BE823411A (ja)
CA (1) CA1001626A (ja)
CH (1) CH612417A5 (ja)
CS (1) CS185669B2 (ja)
DD (1) DD118421A1 (ja)
ES (1) ES433145A1 (ja)
FR (1) FR2255058B1 (ja)
GB (1) GB1441359A (ja)
IE (1) IE40310B1 (ja)
IL (1) IL46259A (ja)
LU (2) LU71514A1 (ja)
PL (1) PL94095B1 (ja)
RO (1) RO69147A (ja)
SU (1) SU547174A3 (ja)
YU (1) YU36492B (ja)
ZA (1) ZA748067B (ja)

Families Citing this family (30)

* Cited by examiner, † Cited by third party
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US4177280A (en) * 1978-07-03 1979-12-04 Syntex (U.S.A.) Inc. Bicyclo[3.1.0]hexyl-substituted carbonylaminophenoxy cardiovascular agents
JPS5757231U (ja) * 1980-09-19 1982-04-03
US4470965A (en) * 1982-10-27 1984-09-11 Usv Pharmaceutical Corporation Celiprolol for the treatment of glaucoma
JPS60164639A (ja) * 1984-02-07 1985-08-27 Hitachi Ltd 燃料噴射弁の駆動制御装置
DE3410380A1 (de) * 1984-03-21 1985-10-10 Lentia GmbH Chem. u. pharm. Erzeugnisse - Industriebedarf, 8000 München S(-)-celiprolol, dessen pharmazeutisch vertraegliche salze, verfahren zu dessen herstellung, verwendung in der therapie und pharmazeutische zubereitungen
DE3544172A1 (de) * 1985-12-13 1987-06-19 Lentia Gmbh Neue kristalline salze von aryloxy-propanolaminen, verfahren zu ihrer herstellung und ihre verwendung
DE3636209A1 (de) * 1986-10-24 1988-04-28 Lentia Gmbh Verfahren zur herstellung eines bindemittelfreien tablettierfaehigen celiprololhydrochlorid-granulates
AP2005003232A0 (en) 2002-08-19 2005-03-31 Pfizer Prod Inc Combination therapy for hyperproliferative diseases.
JP4901474B2 (ja) * 2003-05-30 2012-03-21 ランバクシー ラボラトリーズ リミテッド 置換ピロール誘導体
GT200600381A (es) 2005-08-25 2007-03-28 Compuestos organicos
WO2007029155A2 (en) * 2005-09-05 2007-03-15 Ranbaxy Laboratories Limited An improved process for preparation of pure celiprolol base
US7741317B2 (en) 2005-10-21 2010-06-22 Bristol-Myers Squibb Company LXR modulators
KR101329112B1 (ko) * 2005-11-08 2013-11-14 랜박시 래보러터리스 리미티드 (3ｒ,5ｒ)-7-〔2-(4-플루오로페닐)-5-이소프로필-3-페닐-4-〔(4-히드록시 메틸 페닐 아미노)카르보닐〕-피롤-1-일〕-3,5-디히드록시 헵탄산 헤미 칼슘염의 제조 방법
US7888376B2 (en) 2005-11-23 2011-02-15 Bristol-Myers Squibb Company Heterocyclic CETP inhibitors
US20070238716A1 (en) * 2006-03-14 2007-10-11 Murthy Ayanampudi S R Statin stabilizing dosage formulations
EP2049102A4 (en) * 2006-07-14 2010-12-22 Ranbaxy Lab Ltd POLYMORPHIC FORMS OF AN HMG COA REDUCTASE HEATHER AND USE
ES2382009T3 (es) 2006-12-01 2012-06-04 Bristol-Myers Squibb Company Derivados de N-((3-bencil)-2,2-(bis-fenil-)-propan-1-amina como inhibidores de CETP para el tratamiento de aterosclerosis y enfermedades cardiovasculares
CA3089569C (en) 2007-06-04 2023-12-05 Synergy Pharmaceuticals Inc. Agonists of guanylate cyclase useful for the treatment of gastrointestinal disorders, inflammation, cancer and other disorders
US8969514B2 (en) 2007-06-04 2015-03-03 Synergy Pharmaceuticals, Inc. Agonists of guanylate cyclase useful for the treatment of hypercholesterolemia, atherosclerosis, coronary heart disease, gallstone, obesity and other cardiovascular diseases
US20100120694A1 (en) 2008-06-04 2010-05-13 Synergy Pharmaceuticals, Inc. Agonists of Guanylate Cyclase Useful for the Treatment of Gastrointestinal Disorders, Inflammation, Cancer and Other Disorders
EP2050441A1 (en) * 2007-10-19 2009-04-22 Université Victor Segalen Bordeaux 2 Use of beta blocker for the manufacture of a medicament for the treatment of hemangiomas
US8987262B2 (en) 2007-10-19 2015-03-24 Universite de Bordeaux Use of a beta blocker for the manufacture of a medicament for the treatment of hemangiomas
EP2321341B1 (en) 2008-07-16 2017-02-22 Synergy Pharmaceuticals Inc. Agonists of guanylate cyclase useful for the treatment of gastrointestinal, inflammation, cancer and other disorders
US9616097B2 (en) 2010-09-15 2017-04-11 Synergy Pharmaceuticals, Inc. Formulations of guanylate cyclase C agonists and methods of use
EP2970384A1 (en) 2013-03-15 2016-01-20 Synergy Pharmaceuticals Inc. Agonists of guanylate cyclase and their uses
JP2016514670A (ja) 2013-03-15 2016-05-23 シナジー ファーマシューティカルズ インコーポレイテッド 他の薬物と組み合わせたグアニル酸シクラーゼ受容体アゴニスト
CN105143203A (zh) 2013-04-17 2015-12-09 辉瑞大药厂 用于治疗心血管疾病的n-哌啶-3-基苯甲酰胺衍生物
RS65632B1 (sr) 2013-06-05 2024-07-31 Bausch Health Ireland Ltd Ultra-prečišćeni agonisti guanilat-ciklaze c, postupak njihove pripreme i upotrebe
WO2016055901A1 (en) 2014-10-08 2016-04-14 Pfizer Inc. Substituted amide compounds
WO2020150473A2 (en) 2019-01-18 2020-07-23 Dogma Therapeutics, Inc. Pcsk9 inhibitors and methods of use thereof

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1214012A (en) * 1967-12-21 1970-11-25 Allen & Hanburys Ltd Phenylethanolamines
AT292671B (de) * 1967-12-22 1971-09-10 May & Baker Ltd Verfahren zur Herstellung von neuen 3-(4'-Alkanoylamino-2'-acylphenoxy)-2-hydroxy-1-aminopropanen
US3935259A (en) * 1970-01-08 1976-01-27 Ciba-Geigy Corporation New amines and processes for their manufacture
SE354851B (ja) * 1970-02-18 1973-03-26 Haessle Ab
NL7115581A (ja) * 1970-11-13 1972-05-16 Dresden Arzneimittel
GB1396322A (en) * 1971-06-15 1975-06-04 Ici Ltd Alkanolamine derivatives
SE386892B (sv) * 1972-07-06 1976-08-23 Haessle Ab Forfarande for framstellning av oxaminoforeningar
GB1455116A (en) * 1972-12-15 1976-11-10 Ici Ltd Pharmaceutical compositions
AT330150B (de) * 1973-02-28 1976-06-10 Boehringer Sohn Ingelheim Verfahren zur herstellung von neuen 1-phenoxy-2-hydroxy -3- propargylaminopropanen und von deren saureadditionssalzen
GB1460593A (en) * 1973-06-22 1977-01-06 Ici Ltd Ethanolamine derivatives
FI65987C (fi) * 1973-12-12 1984-08-10 Ici Ltd Foerfarande foer framstaellning av nya terapeutiskt anvaendbara alkanolaminderivat
AT334386B (de) * 1973-12-21 1976-01-10 Chemie Linz Ag Verfahren zur herstellung von neuen phenoxypropylaminderivaten und deren salzen

Also Published As

Publication number Publication date
CS185669B2 (en) 1978-10-31
FR2255058A1 (ja) 1975-07-18
IL46259A (en) 1978-04-30
BE823411A (fr) 1975-06-16
ES433145A1 (es) 1976-11-16
ZA748067B (en) 1976-01-28
JPS5549071B2 (ja) 1980-12-10
IE40310L (en) 1975-06-20
FR2255058B1 (ja) 1978-07-28
AT334385B (de) 1976-01-10
IE40310B1 (en) 1979-04-25
CH612417A5 (ja) 1979-07-31
US4034009A (en) 1977-07-05
JPS5412461B2 (ja) 1979-05-23
PL94095B1 (ja) 1977-07-30
ATA1066673A (de) 1976-05-15
GB1441359A (en) 1976-06-30
LU88296I2 (fr) 1994-05-04
YU36492B (en) 1984-02-29
SU547174A3 (ru) 1977-02-15
YU327774A (en) 1982-02-25
AU7653874A (en) 1976-06-17
CA1001626A (en) 1976-12-14
LU71514A1 (ja) 1975-08-20
JPS5095246A (ja) 1975-07-29
RO69147A (ro) 1981-07-30
IL46259A0 (en) 1975-03-13
DD118421A1 (ja) 1976-03-05

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