ZA748067B - Phenoxypropylamine derivatives and preparation thereof - Google Patents

Phenoxypropylamine derivatives and preparation thereof

Info

Publication number
ZA748067B
ZA748067B ZA00748067A ZA748067A ZA748067B ZA 748067 B ZA748067 B ZA 748067B ZA 00748067 A ZA00748067 A ZA 00748067A ZA 748067 A ZA748067 A ZA 748067A ZA 748067 B ZA748067 B ZA 748067B
Authority
ZA
South Africa
Prior art keywords
preparation
phenoxypropylamine derivatives
phenoxypropylamine
derivatives
Prior art date
Application number
ZA00748067A
Other languages
English (en)
Inventor
Stormann-Menninger-Lerchenthal
G Zoelz
H Pittner
Original Assignee
Chemie Linz Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Chemie Linz Ag filed Critical Chemie Linz Ag
Publication of ZA748067B publication Critical patent/ZA748067B/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D303/00—Compounds containing three-membered rings having one oxygen atom as the only ring hetero atom
    • C07D303/02—Compounds containing oxirane rings
    • C07D303/12—Compounds containing oxirane rings with hydrocarbon radicals, substituted by singly or doubly bound oxygen atoms
    • C07D303/18—Compounds containing oxirane rings with hydrocarbon radicals, substituted by singly or doubly bound oxygen atoms by etherified hydroxyl radicals
    • C07D303/20—Ethers with hydroxy compounds containing no oxirane rings
    • C07D303/22—Ethers with hydroxy compounds containing no oxirane rings with monohydroxy compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C275/00—Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups
    • C07C275/28—Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of urea groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton
    • C07C275/38—Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of urea groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton being further substituted by doubly-bound oxygen atoms

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Cardiology (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
ZA00748067A 1973-12-20 1974-12-18 Phenoxypropylamine derivatives and preparation thereof ZA748067B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
AT1066673A AT334385B (de) 1973-12-20 1973-12-20 Verfahren zur herstellung von neuen phenoxypropylaminderivaten und deren salzen

Publications (1)

Publication Number Publication Date
ZA748067B true ZA748067B (en) 1976-01-28

Family

ID=3623884

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA00748067A ZA748067B (en) 1973-12-20 1974-12-18 Phenoxypropylamine derivatives and preparation thereof

Country Status (19)

Country Link
US (1) US4034009A (ja)
JP (2) JPS5412461B2 (ja)
AT (1) AT334385B (ja)
BE (1) BE823411A (ja)
CA (1) CA1001626A (ja)
CH (1) CH612417A5 (ja)
CS (1) CS185669B2 (ja)
DD (1) DD118421A1 (ja)
ES (1) ES433145A1 (ja)
FR (1) FR2255058B1 (ja)
GB (1) GB1441359A (ja)
IE (1) IE40310B1 (ja)
IL (1) IL46259A (ja)
LU (2) LU71514A1 (ja)
PL (1) PL94095B1 (ja)
RO (1) RO69147A (ja)
SU (1) SU547174A3 (ja)
YU (1) YU36492B (ja)
ZA (1) ZA748067B (ja)

Families Citing this family (30)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4177280A (en) * 1978-07-03 1979-12-04 Syntex (U.S.A.) Inc. Bicyclo[3.1.0]hexyl-substituted carbonylaminophenoxy cardiovascular agents
JPS5757231U (ja) * 1980-09-19 1982-04-03
US4470965A (en) * 1982-10-27 1984-09-11 Usv Pharmaceutical Corporation Celiprolol for the treatment of glaucoma
JPS60164639A (ja) * 1984-02-07 1985-08-27 Hitachi Ltd 燃料噴射弁の駆動制御装置
DE3410380A1 (de) * 1984-03-21 1985-10-10 Lentia GmbH Chem. u. pharm. Erzeugnisse - Industriebedarf, 8000 München S(-)-celiprolol, dessen pharmazeutisch vertraegliche salze, verfahren zu dessen herstellung, verwendung in der therapie und pharmazeutische zubereitungen
DE3544172A1 (de) * 1985-12-13 1987-06-19 Lentia Gmbh Neue kristalline salze von aryloxy-propanolaminen, verfahren zu ihrer herstellung und ihre verwendung
DE3636209A1 (de) * 1986-10-24 1988-04-28 Lentia Gmbh Verfahren zur herstellung eines bindemittelfreien tablettierfaehigen celiprololhydrochlorid-granulates
JP3835763B2 (ja) 2002-08-19 2006-10-18 ファイザー・プロダクツ・インク 増殖亢進疾患のための組み合わせ治療
WO2004106299A2 (en) * 2003-05-30 2004-12-09 Ranbaxy Laboratories Limited Substituted pyrrole derivatives and their use as hmg-co inhibitors
GT200600381A (es) 2005-08-25 2007-03-28 Compuestos organicos
WO2007029155A2 (en) * 2005-09-05 2007-03-15 Ranbaxy Laboratories Limited An improved process for preparation of pure celiprolol base
US7741317B2 (en) 2005-10-21 2010-06-22 Bristol-Myers Squibb Company LXR modulators
WO2007054896A1 (en) * 2005-11-08 2007-05-18 Ranbaxy Laboratories Limited Process for (3r, 5r)-7-[2-(4-fluorophenyl)-5-isopropyl-3-phenyl-4- [(4-hydroxy methyl phenyl amino) carbonyl]-pyrrol-1-yl]-3, 5-dihydroxy-heptanoic acid hemi calcium salt
US7888376B2 (en) 2005-11-23 2011-02-15 Bristol-Myers Squibb Company Heterocyclic CETP inhibitors
WO2008020314A2 (en) * 2006-03-14 2008-02-21 Ranbaxy Laboratories Limited Statin stabilizing dosage formulations
RU2009105089A (ru) * 2006-07-14 2010-08-27 Ранбакси Лабораториз Лимитед (In) ПОЛИМОРФНЫЕ ФОРМЫ ГМГ-КоА-РЕДУКТАЗЫ И ИХ ПРИМЕНЕНИЕ
ES2382009T3 (es) 2006-12-01 2012-06-04 Bristol-Myers Squibb Company Derivados de N-((3-bencil)-2,2-(bis-fenil-)-propan-1-amina como inhibidores de CETP para el tratamiento de aterosclerosis y enfermedades cardiovasculares
US8969514B2 (en) 2007-06-04 2015-03-03 Synergy Pharmaceuticals, Inc. Agonists of guanylate cyclase useful for the treatment of hypercholesterolemia, atherosclerosis, coronary heart disease, gallstone, obesity and other cardiovascular diseases
US20100120694A1 (en) 2008-06-04 2010-05-13 Synergy Pharmaceuticals, Inc. Agonists of Guanylate Cyclase Useful for the Treatment of Gastrointestinal Disorders, Inflammation, Cancer and Other Disorders
US8034782B2 (en) 2008-07-16 2011-10-11 Synergy Pharmaceuticals, Inc. Agonists of guanylate cyclase useful for the treatment of gastrointestinal disorders, inflammation, cancer and other disorders
EP2527360B1 (en) 2007-06-04 2015-10-28 Synergy Pharmaceuticals Inc. Agonists of guanylate cyclase useful for the treatment of gastrointestinal disorders, inflammation, cancer and other disorders
US8987262B2 (en) 2007-10-19 2015-03-24 Universite de Bordeaux Use of a beta blocker for the manufacture of a medicament for the treatment of hemangiomas
EP2050441A1 (en) * 2007-10-19 2009-04-22 Université Victor Segalen Bordeaux 2 Use of beta blocker for the manufacture of a medicament for the treatment of hemangiomas
US9616097B2 (en) 2010-09-15 2017-04-11 Synergy Pharmaceuticals, Inc. Formulations of guanylate cyclase C agonists and methods of use
CA2905435A1 (en) 2013-03-15 2014-09-25 Synergy Pharmaceuticals Inc. Compositions useful for the treatment of gastrointestinal disorders
EP2970384A1 (en) 2013-03-15 2016-01-20 Synergy Pharmaceuticals Inc. Agonists of guanylate cyclase and their uses
BR112015026513A2 (pt) 2013-04-17 2017-07-25 Pfizer derivados de n-piperidin-3-ilbenzamida para tratar as doenças cardiovasculares
EA201592263A1 (ru) 2013-06-05 2016-05-31 Синерджи Фармасьютикалз, Инк. Ультрачистые агонисты гуанилатциклазы c, способ их получения и использования
WO2016055901A1 (en) 2014-10-08 2016-04-14 Pfizer Inc. Substituted amide compounds
EA202191892A1 (ru) 2019-01-18 2022-02-24 Астразенека Аб Ингибиторы pcsk9 и способы их применения

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1214012A (en) * 1967-12-21 1970-11-25 Allen & Hanburys Ltd Phenylethanolamines
AT292671B (de) * 1967-12-22 1971-09-10 May & Baker Ltd Verfahren zur Herstellung von neuen 3-(4'-Alkanoylamino-2'-acylphenoxy)-2-hydroxy-1-aminopropanen
US3935259A (en) * 1970-01-08 1976-01-27 Ciba-Geigy Corporation New amines and processes for their manufacture
SE354851B (ja) * 1970-02-18 1973-03-26 Haessle Ab
NL7115581A (ja) * 1970-11-13 1972-05-16 Dresden Arzneimittel
GB1396322A (en) * 1971-06-15 1975-06-04 Ici Ltd Alkanolamine derivatives
SE386892B (sv) * 1972-07-06 1976-08-23 Haessle Ab Forfarande for framstellning av oxaminoforeningar
GB1455116A (en) * 1972-12-15 1976-11-10 Ici Ltd Pharmaceutical compositions
AT330150B (de) * 1973-02-28 1976-06-10 Boehringer Sohn Ingelheim Verfahren zur herstellung von neuen 1-phenoxy-2-hydroxy -3- propargylaminopropanen und von deren saureadditionssalzen
GB1460593A (en) * 1973-06-22 1977-01-06 Ici Ltd Ethanolamine derivatives
FI65987C (fi) * 1973-12-12 1984-08-10 Ici Ltd Foerfarande foer framstaellning av nya terapeutiskt anvaendbara alkanolaminderivat
AT334386B (de) * 1973-12-21 1976-01-10 Chemie Linz Ag Verfahren zur herstellung von neuen phenoxypropylaminderivaten und deren salzen

Also Published As

Publication number Publication date
YU36492B (en) 1984-02-29
JPS5549071B2 (ja) 1980-12-10
LU71514A1 (ja) 1975-08-20
CS185669B2 (en) 1978-10-31
YU327774A (en) 1982-02-25
ES433145A1 (es) 1976-11-16
US4034009A (en) 1977-07-05
CH612417A5 (ja) 1979-07-31
CA1001626A (en) 1976-12-14
IL46259A0 (en) 1975-03-13
RO69147A (ro) 1981-07-30
PL94095B1 (ja) 1977-07-30
LU88296I2 (fr) 1994-05-04
DD118421A1 (ja) 1976-03-05
ATA1066673A (de) 1976-05-15
BE823411A (fr) 1975-06-16
IE40310B1 (en) 1979-04-25
FR2255058B1 (ja) 1978-07-28
IE40310L (en) 1975-06-20
SU547174A3 (ru) 1977-02-15
FR2255058A1 (ja) 1975-07-18
JPS53149947A (en) 1978-12-27
GB1441359A (en) 1976-06-30
JPS5095246A (ja) 1975-07-29
IL46259A (en) 1978-04-30
AU7653874A (en) 1976-06-17
AT334385B (de) 1976-01-10
JPS5412461B2 (ja) 1979-05-23

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